Acute renal failure associated with albendazole therapy in a patient with trichinosis

Cassandra M arie Batzlaff, Jakrapun Pupaibool, M. Rizwan Sohail

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

A 72-year-old Caucasian woman presented with a 3-week history of confusion, cramping abdominal pain, nausea, vomiting, diarrhoea, fatigue and dehydration. By history, she reported consumption of raw pork and bacon that was salted and cured in brine, but not boiled or cooked. Laboratory testing was significant for an absolute eosinophil count of 3.09×10(9)/L. She was found to have a positive Trichinella serology by ELISA testing. Based on history of raw pork consumption, symptoms, peripheral eosinophilia and positive serology, a diagnosis of trichinosis was made. Treatment was started with oral albendazole. Following initiation of therapy, the patient developed acute kidney injury presumably secondary to albendazole. Therapy was discontinued. Her serum creatinine returned to baseline over the following days. The decision was made to proceed with observation alone, as she did not tolerate treatment. At the 3-week follow-up, her gastrointestinal symptoms had improved and her eosinophilia had resolved.

Original languageEnglish (US)
JournalBMJ Case Reports
Volume2014
DOIs
StatePublished - 2014

Fingerprint

Trichinellosis
Albendazole
Acute Kidney Injury
Eosinophilia
Serology
Trichinella
Therapeutics
Dehydration
Eosinophils
Nausea
Abdominal Pain
Vomiting
Fatigue
Diarrhea
Creatinine
History
Enzyme-Linked Immunosorbent Assay
Observation
Serum
Red Meat

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Acute renal failure associated with albendazole therapy in a patient with trichinosis. / Batzlaff, Cassandra M arie; Pupaibool, Jakrapun; Sohail, M. Rizwan.

In: BMJ Case Reports, Vol. 2014, 2014.

Research output: Contribution to journalArticle

Batzlaff, Cassandra M arie ; Pupaibool, Jakrapun ; Sohail, M. Rizwan. / Acute renal failure associated with albendazole therapy in a patient with trichinosis. In: BMJ Case Reports. 2014 ; Vol. 2014.
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