Acute changes in lipoprotein subclasses during exercise

Esben Søndergaard; Marianne K. Poulsen; Michael D. Jensen; Søren Nielsen

doi:10.1016/j.metabol.2013.08.011

Acute changes in lipoprotein subclasses during exercise

Esben Søndergaard, Marianne K. Poulsen, Michael D. Jensen, Søren Nielsen

Endocrinology, Diabetes, Metabolism, and Nutrition

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Objective Lipids are important substrates for oxidation in the basal fasting state and during exercise. Studies have demonstrated beneficial changes in lipoprotein subclass composition the day after an exercise bout. However, the acute effect of exercise on TG concentration and lipoprotein subclass composition remains unclear. Materials/Methods Sixteen lean, healthy individuals (8 men and 8 women) were recruited (age 20-30 years, BMI < 25 kg/m ²). The subjects were studied during basal fasting conditions as well as during and after 90 min of cycling at 50% of VO₂peak. Lipoprotein subclass composition was measured with ¹H NMR spectroscopy. Results During exercise, LDL and HDL particle concentration increased significantly (p < 0.05) despite lower total TG concentration. In addition, exercise resulted in a shift towards smaller VLDL particles in men (p < 0.05), but VLDL-TG concentration was unaltered. Conclusions Acute exercise induces beneficial changes in lipoprotein subclass composition. These changes are similar to the effects of exercise training.

Original language	English (US)
Pages (from-to)	61-68
Number of pages	8
Journal	Metabolism: Clinical and Experimental
Volume	63
Issue number	1
DOIs	https://doi.org/10.1016/j.metabol.2013.08.011
State	Published - Jan 2014

Keywords

H NMR spectroscopy
HDL
LDL
Triglyceride
VLDL

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Endocrinology

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10.1016/j.metabol.2013.08.011

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title = "Acute changes in lipoprotein subclasses during exercise",

abstract = "Objective Lipids are important substrates for oxidation in the basal fasting state and during exercise. Studies have demonstrated beneficial changes in lipoprotein subclass composition the day after an exercise bout. However, the acute effect of exercise on TG concentration and lipoprotein subclass composition remains unclear. Materials/Methods Sixteen lean, healthy individuals (8 men and 8 women) were recruited (age 20-30 years, BMI < 25 kg/m 2). The subjects were studied during basal fasting conditions as well as during and after 90 min of cycling at 50% of VO2peak. Lipoprotein subclass composition was measured with 1H NMR spectroscopy. Results During exercise, LDL and HDL particle concentration increased significantly (p < 0.05) despite lower total TG concentration. In addition, exercise resulted in a shift towards smaller VLDL particles in men (p < 0.05), but VLDL-TG concentration was unaltered. Conclusions Acute exercise induces beneficial changes in lipoprotein subclass composition. These changes are similar to the effects of exercise training.",

keywords = "H NMR spectroscopy, HDL, LDL, Triglyceride, VLDL",

author = "Esben S{\o}ndergaard and Poulsen, {Marianne K.} and Jensen, {Michael D.} and S{\o}ren Nielsen",

note = "Funding Information: This work was supported by grants from the Danish Medical Research Council , the Novo Nordic Foundation , and the Danish Diabetes Foundation (to S.N.). ",

year = "2014",

month = jan,

doi = "10.1016/j.metabol.2013.08.011",

language = "English (US)",

volume = "63",

pages = "61--68",

journal = "Metabolism: Clinical and Experimental",

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T1 - Acute changes in lipoprotein subclasses during exercise

AU - Søndergaard, Esben

AU - Poulsen, Marianne K.

AU - Jensen, Michael D.

AU - Nielsen, Søren

N1 - Funding Information: This work was supported by grants from the Danish Medical Research Council , the Novo Nordic Foundation , and the Danish Diabetes Foundation (to S.N.).

PY - 2014/1

Y1 - 2014/1

N2 - Objective Lipids are important substrates for oxidation in the basal fasting state and during exercise. Studies have demonstrated beneficial changes in lipoprotein subclass composition the day after an exercise bout. However, the acute effect of exercise on TG concentration and lipoprotein subclass composition remains unclear. Materials/Methods Sixteen lean, healthy individuals (8 men and 8 women) were recruited (age 20-30 years, BMI < 25 kg/m 2). The subjects were studied during basal fasting conditions as well as during and after 90 min of cycling at 50% of VO2peak. Lipoprotein subclass composition was measured with 1H NMR spectroscopy. Results During exercise, LDL and HDL particle concentration increased significantly (p < 0.05) despite lower total TG concentration. In addition, exercise resulted in a shift towards smaller VLDL particles in men (p < 0.05), but VLDL-TG concentration was unaltered. Conclusions Acute exercise induces beneficial changes in lipoprotein subclass composition. These changes are similar to the effects of exercise training.

AB - Objective Lipids are important substrates for oxidation in the basal fasting state and during exercise. Studies have demonstrated beneficial changes in lipoprotein subclass composition the day after an exercise bout. However, the acute effect of exercise on TG concentration and lipoprotein subclass composition remains unclear. Materials/Methods Sixteen lean, healthy individuals (8 men and 8 women) were recruited (age 20-30 years, BMI < 25 kg/m 2). The subjects were studied during basal fasting conditions as well as during and after 90 min of cycling at 50% of VO2peak. Lipoprotein subclass composition was measured with 1H NMR spectroscopy. Results During exercise, LDL and HDL particle concentration increased significantly (p < 0.05) despite lower total TG concentration. In addition, exercise resulted in a shift towards smaller VLDL particles in men (p < 0.05), but VLDL-TG concentration was unaltered. Conclusions Acute exercise induces beneficial changes in lipoprotein subclass composition. These changes are similar to the effects of exercise training.

KW - H NMR spectroscopy

KW - HDL

KW - LDL

KW - Triglyceride

KW - VLDL

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Acute changes in lipoprotein subclasses during exercise

Abstract

Keywords

ASJC Scopus subject areas

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