Abstract
Aim: To design a scoring instrument for rating overall survival (OS) of patients with metastatic epidural sinal cord compression (MESCC) from gynecological malignancies. Patients and Methods: In 22 patients treated with radiotherapy alone for MESCC from gynecological malignancies, ten factors were analyzed for effects on OS. Factors significantly associated with OS on multivariate analysis were included in a scoring instrument. Results: On multivariate analyses, no visceral metastases (p=0.004) and affection of 1-2 vertebrae (p=0.012) were significant. Scoring points for each factor were 0 or 1, depending on OS rates. After summing, scores of 0 (n=6), 1 (n=9) or 2 points (n=9) were obtained. OS rates were 0%, 78% and 100%, respectively, at 3 months and 0%, 33% and 86%, respectively, at 6 months (p<0.001). Conclusion: An instrument was developed for estimating the lifespan of patients with MESCC from gynecological malignancies. This instrument can support physicians when picking an individual treatment.
Original language | English (US) |
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Pages (from-to) | 5469-5472 |
Number of pages | 4 |
Journal | Anticancer research |
Volume | 36 |
Issue number | 10 |
DOIs | |
State | Published - Oct 2016 |
Keywords
- Gynecological cancer
- MESCC
- Overall survival
- Radiotherapy
- Scoring instrument
ASJC Scopus subject areas
- Oncology
- Cancer Research