A scoring instrument to predict the survival prognoses of patients with metastatic epidural spinal cord compression from gynecological malignancies

Stefan Janssen, Amira Bajrovic, Steven E. Schild, Dirk Rades

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Aim: To design a scoring instrument for rating overall survival (OS) of patients with metastatic epidural sinal cord compression (MESCC) from gynecological malignancies. Patients and Methods: In 22 patients treated with radiotherapy alone for MESCC from gynecological malignancies, ten factors were analyzed for effects on OS. Factors significantly associated with OS on multivariate analysis were included in a scoring instrument. Results: On multivariate analyses, no visceral metastases (p=0.004) and affection of 1-2 vertebrae (p=0.012) were significant. Scoring points for each factor were 0 or 1, depending on OS rates. After summing, scores of 0 (n=6), 1 (n=9) or 2 points (n=9) were obtained. OS rates were 0%, 78% and 100%, respectively, at 3 months and 0%, 33% and 86%, respectively, at 6 months (p<0.001). Conclusion: An instrument was developed for estimating the lifespan of patients with MESCC from gynecological malignancies. This instrument can support physicians when picking an individual treatment.

Original languageEnglish (US)
Pages (from-to)5469-5472
Number of pages4
JournalAnticancer Research
Volume36
Issue number10
DOIs
StatePublished - Oct 1 2016

Keywords

  • Gynecological cancer
  • MESCC
  • Overall survival
  • Radiotherapy
  • Scoring instrument

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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