A method for determination of the anisotropic properties of biomembranes

Zong Ping Luo, John Grabowski, Kai Nan An

Research output: Contribution to journalArticle

Abstract

A methodology was developed for potential determination of the anisotropic properties of biomembranes. This method is based on the theoretical discretization of a continuous membrane used for finite element analysis and the simultaneous measurement of the displacement of nodes on the surface of a membrane. From the given loads and measured nodal displacements, one can assemble the resulting stiffness matrix and approximate the material properties associated with the membrane. Mathematical estimations and computer simulations were performed to determine the perturbation of load and displacement errors on the resulting material properties. The results indicated that the material properties are particularly sensitive to displacement errors. The displacement measurements may require an accuracy of 20μm for a 4 x 4 cm2 specimen. Significant inaccuracies occur close to the points of load application.

Original languageEnglish (US)
Pages (from-to)125-132
Number of pages8
JournalJournal of Biomedical Materials Research
Volume32
Issue number1
DOIs
StatePublished - Sep 1 1996

ASJC Scopus subject areas

  • Biomaterials
  • Biomedical Engineering

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