A member of the ras gene superfamily is expressed specifically in T, B and myeloid hemopoietic cells

N. V. Shirsat, R. J. Pignolo, B. L. Kreider, G. Rovera

Research output: Contribution to journalArticle

88 Scopus citations

Abstract

A 1.26 kb murine cDNA having 31% homology with human ras and 55% homology with human rho proteins was isolated using an oligonucleotide probe homologous to catalytic subdomain of a tyrosine kinase subfamily. Northern blot analysis indicates that the expression of the murine gene is restricted to the cells of hemopoietic lineages and the mRNA levels increase with the terminal differentiation of hemopoietic cells into granulocytes.

Original languageEnglish (US)
Pages (from-to)769-772
Number of pages4
JournalOncogene
Volume5
Issue number5
StatePublished - Jun 6 1990

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Cancer Research

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