A Guide to Utilization of the Microbiology Laboratory for Diagnosis of Infectious Diseases: 2018 Update by the Infectious Diseases Society of America and the American Society for Microbiology

J. Michael Miller, Matthew J. Binnicker, Sheldon Campbell, Karen C. Carroll, Kimberle C. Chapin, Peter H. Gilligan, Mark D. Gonzalez, Robert C. Jerris, Sue C. Kehl, Robin Patel, Bobbi S. Pritt, Sandra S. Richter, Barbara Robinson-Dunn, Joseph D. Schwartzman, James W. Snyder, Sam Telford, Elitza S. Theel, Richard B. Thomson, Melvin P. Weinstein, Joseph D. Yao

Research output: Contribution to journalArticle

63 Scopus citations

Abstract

The critical nature of the microbiology laboratory in infectious disease diagnosis calls for a close, positive working relationship between the physician/advanced practice provider and the microbiologists who provide enormous value to the healthcare team. This document, developed by experts in laboratory and adult and pediatric clinical medicine, provides information on which tests are valuable and in which contexts, and on tests that add little or no value for diagnostic decisions. This document presents a system-based approach rather than specimen-based approach, and includes bloodstream and cardiovascular system infections, central nervous system infections, ocular infections, soft tissue infections of the head and neck, upper and lower respiratory infections, infections of the gastrointestinal tract, intra-abdominal infections, bone and joint infections, urinary tract infections, genital infections, and other skin and soft tissue infections; or into etiologic agent groups, including arthropod-borne infections, viral syndromes, and blood and tissue parasite infections. Each section contains introductory concepts, a summary of key points, and detailed tables that list suspected agents; the most reliable tests to order; the samples (and volumes) to collect in order of preference; specimen transport devices, procedures, times, and temperatures; and detailed notes on specific issues regarding the test methods, such as when tests are likely to require a specialized laboratory or have prolonged turnaround times. In addition, the pediatric needs of specimen management are also emphasized. There is intentional redundancy among the tables and sections, as many agents and assay choices overlap. The document is intended to serve as a guidance for physicians in choosing tests that will aid them to quickly and accurately diagnose infectious diseases in their patients.

Original languageEnglish (US)
Pages (from-to)e1-e94
JournalClinical Infectious Diseases
Volume67
Issue number6
DOIs
StatePublished - Aug 31 2018

Keywords

  • clinical correlation
  • clinical relevance
  • microbiology specimens.
  • specimen collection
  • specimen management

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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    Miller, J. M., Binnicker, M. J., Campbell, S., Carroll, K. C., Chapin, K. C., Gilligan, P. H., Gonzalez, M. D., Jerris, R. C., Kehl, S. C., Patel, R., Pritt, B. S., Richter, S. S., Robinson-Dunn, B., Schwartzman, J. D., Snyder, J. W., Telford, S., Theel, E. S., Thomson, R. B., Weinstein, M. P., & Yao, J. D. (2018). A Guide to Utilization of the Microbiology Laboratory for Diagnosis of Infectious Diseases: 2018 Update by the Infectious Diseases Society of America and the American Society for Microbiology. Clinical Infectious Diseases, 67(6), e1-e94. https://doi.org/10.1093/cid/ciy381