1,25-Dihydroxyvitamin D3 receptors in developing dorsal root ganglia of fetal rats

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38 Scopus citations

Abstract

We observed immunostaining for the 1,25-dihydroxyvitamin D3 receptor (VDR) and calbindin-D(28k) in neurons, but not glial cells, of fetal rat dorsal root ganglia (DRG) from days 13 through 21 of gestation. Dispersed cultures of DRG collected from rat fetuses at gestational day 15 also contained epitopes for VDR and calbindin-D(28k) in neurons, but not in glial cells. 1,25-Dihydroxyvitamin D3, through VDR, may perform significant functions in the development of neuronal cells.

Original languageEnglish (US)
Pages (from-to)120-124
Number of pages5
JournalDevelopmental Brain Research
Volume92
Issue number1
DOIs
StatePublished - Mar 29 1996

Keywords

  • 1,25-Dihydroxyvitamin D receptor
  • Calbindin-D(28k)
  • Dorsal root ganglia
  • Fetal
  • Neuron
  • Rat

ASJC Scopus subject areas

  • Developmental Neuroscience
  • Developmental Biology

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