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Xiaolei H Xu, PhD

  • 6339 Citations
  • 24 Scopus h-Index
19972019
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Zebrafish Medicine & Life Sciences
Cardiomyopathies Medicine & Life Sciences
Sarcomeres Medicine & Life Sciences
Dilated Cardiomyopathy Medicine & Life Sciences
Sirolimus Medicine & Life Sciences
Connectin Medicine & Life Sciences
Cardiac Myocytes Medicine & Life Sciences
Catenins Medicine & Life Sciences

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Projects 2005 2019

Microsensors to Study Electrical and Mechanical Coupling of Injured Myocardium

Xu, X. H.

Project: Research project

Discovering cardiomyopathy modifiers in TOR signaling via zebrafish genetics

Xu, X. H.

National Institutes of Health

4/1/11 → 4/30/19

Project: Research project

Zebrafish
Cardiomyopathies
Sirolimus
Autophagy
Modifier Genes

Genetic Studies of Sarcomere-based Cardiac Diseases

Xu, X. H.

National Institutes of Health

8/1/05 → 7/31/16

Project: Research project

Sarcomeres
Heart Diseases
Connectin
Cardiomyopathies
Zebrafish

Research Output 1997 2019

1 Citation (Scopus)

Acquisition, Processing and Analysis of Electrocardiogram in Awake Zebrafish

Le, T., Lenning, M., Clark, I., Bhimani, I., Fortunato, J., Marsh, P., Xu, X. H. & Cao, H., Jun 1 2019, In : IEEE Sensors Journal. 19, 11, p. 4283-4289 7 p., 8636511.

Research output: Contribution to journal › Article

electrocardiography
Electrocardiography
acquisition
drugs
electrophysiology

Displacement analysis of myocardial mechanical deformation (DIAMOND) reveals segmental susceptibility to doxorubicin-induced injury and regeneration

Chen, J., Ding, Y., Chen, M., Gau, J., Jen, N., Nahal, C., Tu, S., Chen, C., Zhou, S., Chang, C. C., Lyu, J., Xu, X. H., Hsiai, T. K. & Packard, R. R. S., Jan 1 2019, In : JCI Insight. 4, 8, e125362.

Research output: Contribution to journal › Article

Open Access
Zebrafish
Doxorubicin
Regeneration
Wounds and Injuries
Mechanics

Haploinsufficiency of mechanistic target of rapamycin ameliorates bag3 cardiomyopathy in adult zebrafish

Ding, Y., Dvornikov, A. V., Ma, X., Zhang, H., Wang, Y., Lowerison, M., Packard, R. R., Wang, L., Chen, J., Zhang, Y., Hsiai, T., Lin, X. & Xu, X., Oct 1 2019, In : Disease models & mechanisms. 12, 10

Research output: Contribution to journal › Article

Open Access
Haploinsufficiency
Zebrafish
Sirolimus
Cardiomyopathies
Dilated Cardiomyopathy

Phenotyping an adult zebrafish lamp2 cardiomyopathy model identifies mTOR inhibition as a candidate therapy

Dvornikov, A. V., Wang, M., Yang, J., Zhu, P., Le, T., Lin, X., Cao, H. & Xu, X. H., Aug 1 2019, In : Journal of Molecular and Cellular Cardiology. 133, p. 199-208 10 p.

Research output: Contribution to journal › Article

Glycogen Storage Disease Type IIb
Hypertrophic Cardiomyopathy
Zebrafish
Cardiomyopathies
Actomyosin
5 Citations (Scopus)

A doxorubicin-induced cardiomyopathy model in adult zebrafish

Ma, X., Ding, Y., Wang, Y. & Xu, X. H., Jun 7 2018, In : Journal of Visualized Experiments. 2018, 136, e57567.

Research output: Contribution to journal › Article

Zebrafish
Cardiomyopathies
Doxorubicin
Genetic Testing
Intraperitoneal Injections