Virginia M Shapiro, PhD

  • 2224 Citations
  • 19 Scopus h-Index
1986 …2021
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  • 8 Similar Profiles
T-Lymphocytes Medicine & Life Sciences
T-cells Chemical Compounds
Interleukin-2 Medicine & Life Sciences
T-Cell Antigen Receptor Medicine & Life Sciences
Transcription Factor AP-1 Medicine & Life Sciences
Up-Regulation Medicine & Life Sciences
Natural Killer T-Cells Medicine & Life Sciences
Chemical activation Chemical Compounds

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Projects 1986 2021

T-Lymphocytes
Co-Repressor Proteins
Jurkat Cells
Thymocytes
Costimulatory and Inhibitory T-Cell Receptors
training program
student
graduate
career
trainee
Erythropoiesis
Erythroblasts
Embryonic Structures
Mitochondria
Iron

Research Output 1995 2019

  • 2224 Citations
  • 19 Scopus h-Index
  • 49 Article

Cutting Edge: HDAC3 Protects Double-Positive Thymocytes from P2X7 Receptor-Induced Cell Death

Philips, R. L., McCue, S. A., Rajcula, M. J. & Shapiro, V. M., Feb 15 2019, In : Journal of immunology (Baltimore, Md. : 1950). 202, 4, p. 1033-1038 6 p.

Research output: Contribution to journalArticle

Purinergic P2X7 Receptors
Thymocytes
Cell Death
Adenosine Triphosphate
Regulatory T-Lymphocytes

HDAC3 restrains CD8-lineage genes to maintain a bi-potential state in CD4+CD8+ thymocytes for CD4-lineage commitment

Philips, R. L., Lee, J. H., Gaonkar, K., Chanana, P., Chung, J. Y., Romero Arocha, S. R., Schwab, A., Ordog, T. & Shapiro, V. M., Jan 18 2019, In : eLife. 8

Research output: Contribution to journalArticle

Thymocytes
Genes
T-cells
T-Lymphocytes
Acetylation

Murine T cell maturation entails protection from Mbl2, but complement proteins do not drive clearance of cells that fail maturation in the absence of NKAP

Dash, B., Belmonte, P. J., Fine, S. R., Shapiro, M. J., Chung, J. Y., Schwab, A. D., McCue, S. A., Rajcula, M. J. & Shapiro, V. M., Jan 1 2019, In : Journal of Immunology. 203, 2, p. 408-417 10 p.

Research output: Contribution to journalArticle

Complement System Proteins
T-Lymphocytes
Thymocytes
Lymphopenia
Lectins

NKAP Must Associate with HDAC3 to Regulate Hematopoietic Stem Cell Maintenance and Survival

Shapiro, M. J., Lehrke, M. J., Chung, J. Y., Romero Arocha, S. & Shapiro, V. M., Apr 15 2019, In : Journal of immunology (Baltimore, Md. : 1950). 202, 8, p. 2287-2295 9 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Cell Survival
Maintenance
Alanine
Fibroblasts

The Chemoattractant Receptor Ebi2 Drives Intranodal Naive CD4 + T Cell Peripheralization to Promote Effective Adaptive Immunity

Baptista, A. P., Gola, A., Huang, Y., Milanez-Almeida, P., Torabi-Parizi, P., Urban, J. F., Shapiro, V. M., Gerner, M. Y. & Germain, R. N., May 21 2019, In : Immunity. 50, 5, p. 1188-1201.e6

Research output: Contribution to journalArticle

Formyl Peptide Receptor
Adaptive Immunity
Lymph Nodes
T-Lymphocytes
Antigens