• 16769 Citations
  • 60 Scopus h-Index
1988 …2020

Research output per year

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Article
2020

Asthma control in eosinophilic granulomatosis with polyangiitis treated with rituximab

Casal Moura, M., Berti, A., Keogh, K. A., Volcheck, G. W., Specks, U. & Baqir, M., May 1 2020, In : Clinical rheumatology. 39, 5, p. 1581-1590 10 p.

Research output: Contribution to journalArticle

Chronic rhinosinusitis in eosinophilic granulomatosis with polyangiitis: clinical presentation and antineutrophil cytoplasmic antibodies

Low, C. M., Keogh, K. A., Saba, E. S., Gruszczynski, N. R., Berti, A., Specks, U., Baqir, M., Smith, B. M., Choby, G., Stokken, J. K. & O'Brien, E. K., Feb 1 2020, In : International Forum of Allergy and Rhinology. 10, 2, p. 217-222 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Eosinophilic Granulomatosis With Polyangiitis: Clinical Predictors of Long-term Asthma Severity

Berti, A., Cornec, D., Casal Moura, M., Smyth, R. J., Dagna, L., Specks, U. & Keogh, K. A., May 2020, In : Chest. 157, 5, p. 1086-1099 14 p.

Research output: Contribution to journalArticle

1 Scopus citations

Evaluation of Potential Serum Biomarkers of Disease Activity in Diverse Forms of Vasculitis

Rodriguez-Pla, A., Warner, R. L., Cuthbertson, D., Carette, S., Khalidi, N. A., Koening, C. L., Langford, C. A., McAlear, C. A., Moreland, L. W., Pagnoux, C., Seo, P., Specks, U., Sreih, A. G., Ytterberg, S. R., Johnson, K. J., Merkel, P. A. & Monach, P. A., Jul 1 2020, In : Journal of Rheumatology. 47, 7, p. 1001-1010 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Plasma exchange and glucocorticoids in severe ANCA-associated vasculitis

Walsh, M., Merkel, P. A., Peh, C. A., Szpirt, W. M., Puechal, X., Fujimoto, S., Hawley, C. M., Khalidi, N., Flosmann, O., Wald, R., Girard, L. P., Levin, A., Gregorini, G., Harper, L., Clark, W. F., Pagnoux, C., Specks, U., Smyth, L., Tesar, V., Ito-Ihara, T. & 15 others, De Zoysa, J. R., Szczeklik, W., Flores-Suarez, L. F., Carette, S., Guillevin, L., Pusey, C. D., Casian, A. L., Brezina, B., Mazzetti, A., McAlear, C. A., Broadhurst, E., Reidlinger, D., Mehta, S., Ives, N. & Jayne, D. R. W., Feb 13 2020, In : New England Journal of Medicine. 382, 7, p. 622-631 10 p.

Research output: Contribution to journalArticle

17 Scopus citations
7 Scopus citations
2019
Open Access
3 Scopus citations

Disease Activity, Antineutrophil Cytoplasmic Antibody Type, and Lipid Levels in Antineutrophil Cytoplasmic Antibody–Associated Vasculitis

Wallace, Z. S., Fu, X., Liao, K., Kallenberg, C. G. M., Langford, C. A., Merkel, P. A., Monach, P., Seo, P., Specks, U., Spiera, R., St.Clair, E. W., Zhang, Y., Choi, H. & Stone, J. H., Nov 1 2019, In : Arthritis and Rheumatology. 71, 11, p. 1879-1887 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Evaluation of clinical benefit from treatment with mepolizumab for patients with eosinophilic granulomatosis with polyangiitis

Steinfeld, J., Bradford, E. S., Brown, J., Mallett, S., Yancey, S. W., Akuthota, P., Cid, M. C., Gleich, G. J., Jayne, D., Khoury, P., Langford, C. A., Merkel, P. A., Moosig, F., Specks, U., Weller, P. F. & Wechsler, M. E., Jun 2019, In : Journal of Allergy and Clinical Immunology. 143, 6, p. 2170-2177 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Exostosin 1/exostosin 2–associated membranous nephropathy

Sethi, S., Madden, B. J., Debiec, H., Cristine Charlesworth, M., Gross, L., Ravindran, A., Hummel, A. M., Specks, U., Fervenza, F. C. & Ronco, P., Jun 2019, In : Journal of the American Society of Nephrology. 30, 6, p. 1123-1136 14 p.

Research output: Contribution to journalArticle

13 Scopus citations

Feasibility and construct validation of the patient reported outcomes measurement information system in systemic vasculitis

Tomasson, G., Farrar, J. T., Cuthbertson, D., McAlear, C. A., Ashdown, S., Cronholm, P. F., Dawson, J., Gebhart, D., Lanier, G., Luqmani, R. A., Milman, N., Peck, J., Robson, J. C., Shea, J. A., Carette, S., Khalidi, N., Koening, C. L., Langford, C. A., Monach, P. A., Moreland, L. & 5 others, Pagnoux, C., Specks, U., Sreih, A. G., Ytterberg, S. R. & Merkel, P. A., Aug 1 2019, In : Journal of Rheumatology. 46, 8, p. 928-934 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Non-Linear Rituximab Pharmacokinetics and Complex Relationship between Rituximab Concentrations and Anti-Neutrophil Cytoplasmic Antibodies (ANCA) in ANCA-Associated Vasculitis: The RAVE Trial Revisited

Bensalem, A., Mulleman, D., Paintaud, G., Azzopardi, N., Gouilleux-Gruart, V., Cornec, D., Specks, U. & Ternant, D., Jan 1 2019, (Accepted/In press) In : Clinical Pharmacokinetics.

Research output: Contribution to journalArticle

1 Scopus citations

Remote activation of a latent epitope in an autoantigen decoded with simulated b-factors

Pang, Y. P., Moura, M. C., Thompson, G. E., Nelson, D. R., Hummel, A. M., Jenne, D. E., Emerling, D., Volkmuth, W., Robinson, W. H. & Specks, U., Jan 1 2019, In : Frontiers in immunology. 10, OCT, 2467.

Research output: Contribution to journalArticle

Open Access

Serum cytokine and chemokine levels in patients with eosinophilic granulomatosis with polyangiitis, hypereosinophilic syndrome, or eosinophilic asthma

Vasculitis Clinical Research Consortium, Mar 1 2019, In : Clinical and experimental rheumatology. 37, 2, p. 40-44 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Subglottic stenosis and endobronchial disease in granulomatosis with polyangiitis

Quinn, K. A., Gelbard, A., Sibley, C., Sirajuddin, A., Ferrada, M. A., Chen, M., Cuthbertson, D., Carette, S., Khalidi, N. A., Koening, C. L., Langford, C. A., Mcalear, C. A., Monach, P. A., Moreland, L. W., Pagnoux, C., Seo, P., Specks, U., Sreih, A. G., Ytterberg, S. R., Merkel, P. A. & 1 others, Grayson, P. C., Dec 1 2019, In : Rheumatology (United Kingdom). 58, 12, p. 2203-2211 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

The association of serum interleukin-6 levels with clinical outcomes in antineutrophil cytoplasmic antibody-associated vasculitis

RAVE-ITN Research Group, Dec 2019, In : Journal of Autoimmunity. 105, 102302.

Research output: Contribution to journalArticle

1 Scopus citations
2018

Acquired cyclic neutropenia associated with cocaine-induced anti-neutrophil cytoplasmic antibodies binding to human neutrophil elastase

Schieppati, F., Gregorini, G., Hummel, A. M., D'Adda, M., Borlenghi, E., Lamorgese, C., Specks, U. & Rossi, G., Jan 1 2018, (Accepted/In press) In : American Journal of Hematology.

Research output: Contribution to journalArticle

Circulating Cytokine Profiles and Antineutrophil Cytoplasmic Antibody Specificity in Patients With Antineutrophil Cytoplasmic Antibody-Associated Vasculitis

Berti, A., Warner, R., Johnson, K., Cornec, D., Schroeder, D., Kabat, B., Langford, C. A., Hoffman, G. S., Fervenza, F. C., Kallenberg, C. G. M., Seo, P., Spiera, R., St.Clair, E. W., Brunetta, P., Stone, J. H., Merkel, P. A., Specks, U. & Monach, P. A., Jan 1 2018, (Accepted/In press) In : Arthritis and Rheumatology.

Research output: Contribution to journalArticle

15 Scopus citations

Pharmacokinetics of rituximab and clinical outcomes in patients with anti-neutrophil cytoplasmic antibody associated vasculitis

Cornec, D., Kabat, B. F., Mills, J. R., Cheu, M., Hummel, A. M., Schroeder, D. R., Cascino, M. D., Brunetta, P., Murray, D. L., Snyder, M. R., Fervenza, F. C., Hoffman, G. S., Kallenberg, C. G. M., Langford, C. A., Merkel, P. A., Monach, P. A., Seo, P., Spiera, R. F., William St Clair, E., Stone, J. H. & 2 others, Barnidge, D. R. & Specks, U., Apr 1 2018, In : Rheumatology (United Kingdom). 57, 4, p. 639-650 12 p.

Research output: Contribution to journalArticle

6 Scopus citations
16 Scopus citations

Role of Macrophage Migration Inhibitory Factor in Granulomatosis With Polyangiitis

Sreih, A. G., Ezzedine, R., Leng, L., Fan, J., Yao, J., Reid, D., Piecychna, M., Carette, S., Cuthbertson, D., Dellaripa, P., Hoffman, G. S., Khalidi, N. A., Koening, C. L., Langford, C. A., Mahr, A., McAlear, C. A., Maksimowicz-Mckinnon, K., Monach, P. A., Seo, P., Specks, U. & 6 others, St.Clair, E. W., Stone, J. H., Ytterberg, S. R., Edberg, J., Merkel, P. A. & Bucala, R., Jan 1 2018, (Accepted/In press) In : Arthritis and Rheumatology.

Research output: Contribution to journalArticle

4 Scopus citations

Serum periostin as a biomarker in eosinophilic granulomatosis with polyangiitis

Rhee, R. L., Holweg, C. T. J., Wong, K., Cuthbertson, D., Carette, S., Khalidi, N. A., Koening, C. L., Langford, C. A., McAlear, C. A., Monach, P. A., Moreland, L. W., Pagnoux, C., Seo, P., Specks, U., Sreih, A. G., Ytterberg, S. R. & Merkel, P. A., Oct 2018, In : PloS one. 13, 10, e0205768.

Research output: Contribution to journalArticle

2 Scopus citations

Severe/uncontrolled asthma and overall survival in atopic patients with eosinophilic granulomatosis with polyangiitis

Berti, A., Volcheck, G. W., Cornec, D., Smyth, R. J., Specks, U. & Keogh, K. A., Sep 1 2018, In : Respiratory Medicine. 142, p. 66-72 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

The utility of urinalysis in determining the risk of renal relapse in ANCA-associated vasculitis

Rhee, R. L., Davis, J. C., Ding, L., Fervenza, F. C., Hoffman, G. S., Kallenberg, C. G. M., Langford, C. A., McCune, W. J., Monach, P. A., Seo, P., Spiera, R., St. Clair, E. W., Specks, U., Stone, J. H. & Merkel, P. A., Feb 7 2018, In : Clinical Journal of the American Society of Nephrology. 13, 2, p. 251-257 7 p.

Research output: Contribution to journalArticle

8 Scopus citations
2017

A Genome-wide Association Study Identifies Risk Alleles in Plasminogen and P4HA2 Associated with Giant Cell Arteritis

Spanish CGA Group, UKGCA Consortium, Vasculitis Clinical Research Consortium, UKGCA Consortium, Vasculitis Clinical Research Consortium & Vasculitis Clinical Research Consortium, Jan 5 2017, In : American journal of human genetics. 100, 1, p. 64-74 11 p.

Research output: Contribution to journalArticle

27 Scopus citations

Association of Serum Calprotectin (S100A8/A9) Level With Disease Relapse in Proteinase 3–Antineutrophil Cytoplasmic Antibody–Associated Vasculitis

the RAVE–Immune Tolerance Network Research Group, Jan 1 2017, In : Arthritis and Rheumatology. 69, 1, p. 185-193 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

Clinical characteristics of inflammatory ocular disease in anti-neutrophil cytoplasmic antibody associated vasculitis: a retrospective cohort study

Ungprasert, P., Crowson, C., Cartin-Ceba, R., Garrity, J. A., Smith, W. M., Specks, U., Matteson, E. L. & Makol, A., Oct 1 2017, In : Rheumatology (Oxford, England). 56, 10, p. 1763-1770 8 p.

Research output: Contribution to journalArticle

9 Scopus citations
23 Scopus citations

Effect of Disease Activity, Glucocorticoid Exposure, and Rituximab on Body Composition During Induction Treatment of Antineutrophil Cytoplasmic Antibody–Associated Vasculitis

Wallace, Z. S., Miloslavsky, E. M., Cascino, M., Unizony, S. H., Lu, N., Hoffman, G. S., Kallenberg, C. G. M., Langford, C. A., Merkel, P. A., Monach, P. A., Seo, P., Spiera, R., St.Clair, E. W., Specks, U., Brunetta, P., Choi, H. K. & Stone, J. H., Jul 1 2017, In : Arthritis Care and Research. 69, 7, p. 1004-1010 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Experience with direct-to-patient recruitment for enrollment into a clinical trial in a rare disease: A web-based study

Krischer, J., Cronholm, P. F., Burroughs, C., McAlear, C. A., Borchin, R., Easley, E., Davis, T., Kullman, J., Carette, S., Khalidi, N., Koening, C., Langford, C. A., Monach, P., Moreland, L., Pagnoux, C., Specks, U., Sreih, A. G., Ytterberg, S. & Merkel, P. A., Feb 2017, In : Journal of medical Internet research. 19, 2, e50.

Research output: Contribution to journalArticle

8 Scopus citations
13 Scopus citations

Identification of Functional and Expression Polymorphisms Associated With Risk for Antineutrophil Cytoplasmic Autoantibody–Associated Vasculitis

for the Vasculitis Clinical Research Consortium, May 2017, In : Arthritis and Rheumatology. 69, 5, p. 1054-1066 13 p.

Research output: Contribution to journalArticle

46 Scopus citations

IgA antibodies to myeloperoxidase in patients with eosinophilic granulomatosis with polyangiitis (Churg-Strauss)

Vasculitis Clinical Research Consortium, Mar 1 2017, In : Clinical and Experimental Rheumatology. 35, 1, p. 98-101 4 p.

Research output: Contribution to journalArticle

7 Scopus citations

Immunoglobulin (Ig)M antibodies to proteinase 3 in granulomatosis with polyangiitis and microscopic polyangiitis

for the WGET and RAVE-ITN Research Groups, Apr 1 2017, In : Clinical and Experimental Immunology. 188, 1, p. 174-181 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Interstitial Immunostaining and Renal Outcomes in Antineutrophil Cytoplasmic Antibody-Associated Glomerulonephritis

Geetha, D., Sethi, S. M., De Vriese, A. S., Specks, U., Kallenberg, C. G. M., Lim, N., Spiera, R., St. Clair, E. W., Merkel, P. A., Seo, P., Monach, P. A., Lepori, N., Fessler, B. J., Langford, C. A., Hoffman, G. S., Sharma, R., Stone, J. H. & Fervenza, F. C., Sep 8 2017, (Accepted/In press) In : American Journal of Nephrology. p. 231-238 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Mepolizumab or placebo for eosinophilic granulomatosis with polyangiitis

EGPA Mepolizumab Study Team, May 18 2017, In : New England Journal of Medicine. 376, 20, p. 1921-1932 12 p.

Research output: Contribution to journalArticle

212 Scopus citations

Non-ischemic cardiomyopathy after rituximab treatment for membranous nephropathy

Cheungpasitporn, W., Kopecky, S. L., Specks, U., Bharucha, K. & Fervenza, F. C., 2017, In : Journal of Renal Injury Prevention. 6, 1, p. 18-25 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Reply

Rovin, B. H., Birmingham, D., Cartin-Ceba, R., Specks, U. & Stone, J. H., 2017, (Accepted/In press) In : Arthritis and Rheumatology.

Research output: Contribution to journalArticle

Revised 2017 international consensus on testing of ANCAs in granulomatosis with polyangiitis and microscopic polyangiitis

Bossuyt, X., Cohen Tervaert, J. W., Arimura, Y., Blockmans, D., Flores-Suáez, L. F., Guillevin, L., Hellmich, B., Jayne, D., Jennette, J. C., Kallenberg, C. G. M., Moiseev, S., Novikov, P., Radice, A., Anne Savige, J., Alberto Sinico, R., Specks, U., Van Paassen, P., Zhao, M. H., Rasmussen, N., Damoiseaux, J. & 1 others, Csernok, E., 2017, In : Nature Reviews Rheumatology. 13, 11, p. 683-692 10 p.

Research output: Contribution to journalArticle

86 Scopus citations
25 Scopus citations
12 Scopus citations
2016

ANCA-associated vasculitis — clinical utility of using ANCA specificity to classify patients

Cornec, D., Gall, E. C. L., Fervenza, F. C. & Specks, U., Jul 28 2016, (Accepted/In press) In : Nature Reviews Rheumatology.

Research output: Contribution to journalArticle

89 Scopus citations

Biopsy-proven pulmonary capillaritis: A retrospective study of aetiologies including an in-depth look at isolated pulmonary capillaritis

Thompson, G., Klecka, M., Roden, A., Specks, U. & Cartin-Ceba, R., 2016, (Accepted/In press) In : Respirology.

Research output: Contribution to journalArticle

11 Scopus citations

Clinical outcomes of treatment of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis based on ANCA type

Unizony, S., Villarreal, M., Miloslavsky, E. M., Lu, N., Merkel, P. A., Spiera, R., Seo, P., Langford, C. A., Hoffman, G. S., Kallenberg, C. G. M., St. Clair, E. W., Ikle, D., Tchao, N. K., Ding, L., Brunetta, P., Choi, H. K., Monach, P. A., Fervenza, F., Stone, J. H. & Specks, U., Jun 2016, In : Annals of the rheumatic diseases. 75, 6, p. 1166-1169 4 p.

Research output: Contribution to journalArticle

88 Scopus citations

Diffuse Alveolar Hemorrhage Secondary to Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: Predictors of Respiratory Failure and Clinical Outcomes

Cartin-Ceba, R., Diaz-Caballero, L., Al-Qadi, M. O., Tryfon, S., Fervenza, F. C., Ytterberg, S. R. & Specks, U., Jun 1 2016, In : Arthritis and Rheumatology. 68, 6, p. 1467-1476 10 p.

Research output: Contribution to journalArticle

35 Scopus citations

Factors Determining the Clinical Utility of Serial Measurements of Antineutrophil Cytoplasmic Antibodies Targeting Proteinase 3

for the Rituximab in ANCA-Associated Vasculitis–Immune Tolerance Network Research Group, Jul 1 2016, In : Arthritis and Rheumatology. 68, 7, p. 1700-1710 11 p.

Research output: Contribution to journalArticle

58 Scopus citations

Inhibitors and antibody fragments as potential anti-inflammatory therapeutics targeting neutrophil proteinase 3 in human disease

Korkmaz, B., Lesner, A., Guarino, C., Wysocka, M., Kellenberger, C., Watier, H., Specks, U., Gauthier, F. & Jenne, D. E., Jun 1 2016, In : Pharmacological Reviews. 68, 3, p. 603-630 28 p.

Research output: Contribution to journalArticle

15 Scopus citations