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Rish Pai, MD, PhD

20012024

Research activity per year

Search results

  • 2024

    Allometric versus traditional body-shape indices and risk of colorectal cancer: a Mendelian randomization analysis

    Rontogianni, M. O., Bouras, E., Aglago, E. K., Freisling, H., Murphy, N., Cotterchio, M., Hampe, J., Lindblom, A., Pai, R. K., Pharoah, P. D. P., Phipps, A. I., van Duijnhoven, F. J. B., Visvanathan, K., van Guelpen, B., Li, C. I., Brenner, H., Pellatt, A. J., Ogino, S., Gunter, M. J., Peters, U., & 2 othersChristakoudi, S. & Tsilidis, K. K., 2024, (Accepted/In press) In: International Journal of Obesity.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • An End-to-End Platform for Digital Pathology Using Hyperspectral Autofluorescence Microscopy and Deep Learning-Based Virtual Histology

    McNeil, C., Wong, P. F., Sridhar, N., Wang, Y., Santori, C., Wu, C. H., Homyk, A., Gutierrez, M., Behrooz, A., Tiniakos, D., Burt, A. D., Pai, R. K., Tekiela, K., Patel, H., Cameron Chen, P. H., Fischer, L., Martins, E. B., Seyedkazemi, S., Freedman, D., Kim, C. C., & 1 othersCimermancic, P., Feb 2024, In: Modern Pathology. 37, 2, 100377.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Causal relationships between risk of venous thromboembolism and 18 cancers: a bidirectional Mendelian randomization analysis

    InterLymph Consortium & INVENT-MVP Consortium, Feb 1 2024, In: International journal of epidemiology. 53, 1, dyad170.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Circulating white blood cell traits and colorectal cancer risk: A Mendelian randomisation study

    Constantinescu, A. E., Bull, C. J., Jones, N., Mitchell, R., Burrows, K., Dimou, N., Bézieau, S., Brenner, H., Buchanan, D. D., D'Amato, M., Jenkins, M. A., Moreno, V., Pai, R. K., Um, C. Y., White, E., Murphy, N., Gunter, M., Timpson, N. J., Huyghe, J. R. & Vincent, E. E., Jan 1 2024, In: International Journal of Cancer. 154, 1, p. 94-103 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Clinical Data Do Not Reliably Predict Duodenal Histology at Follow-up in Celiac Disease: A 13 Center Correlative Study

    Patel, N., Leffler, D. A., Al-Toma, A., Mulder, C. J., Elli, L., Gan, G., Patil, P., Atsawarungruangkit, A., Kuijpers, K. C., Del Gobbo, A., Goldsmith, J., Hintze, Z., Pacheco, M. C., Vieth, M., Melcher, B., Salomao, M., Pai, R., Hart, J., Olivas, A., Naini, B., & 10 othersMeyerson, C., Choi, W. T., Kakar, S., Westerhoff, M., Cheng, J., Gopal, P., Hammer, S., Moreno Prats, M., Bronner, M. P. & Robert, M. E., Feb 1 2024, In: American Journal of Surgical Pathology. 48, 2, p. 212-220 9 p.

    Research output: Contribution to journal › Article › peer-review

  • Effects of Mirikizumab on Histologic Resolution of Crohn's Disease in a Randomized Controlled Phase 2 Trial

    Magro, F., Protic, M., De Hertogh, G., Chan, L. S., Pollack, P., Jairath, V., Carlier, H., Hon, E., Feagan, B. G., Harpaz, N., Pai, R. & Reinisch, W., 2024, (Accepted/In press) In: Clinical Gastroenterology and Hepatology.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Epithelial overexpression of IL-33 induces eosinophilic esophagitis dependent on IL-13

    Masuda, M. Y., Pyon, G. C., Luo, H., LeSuer, W. E., Putikova, A., Dao, A., Ortiz, D. R., Schulze, A. R., Fritz, N., Kobayashi, T., Iijima, K., Klein-Szanto, A. J., Shimonosono, M., Flashner, S., Morimoto, M., Pai, R. K., Rank, M. A., Nakagawa, H., Kita, H., Wright, B. L., & 1 othersDoyle, A. D., May 2024, In: Journal of Allergy and Clinical Immunology. 153, 5, p. 1355-1368 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Histologic assessments in ulcerative colitis: the evidence behind a new endpoint in clinical trials

    Pai, R. K., D’Haens, G., Kobayashi, T., Sands, B. E., Travis, S., Jairath, V., De Hertogh, G., Park, B., McGinnis, K., Redondo, I., Lipitz, N. G., Gibble, T. H. & Magro, F., 2024, In: Expert Review of Gastroenterology and Hepatology. 18, 1-3, p. 73-87 15 p.

    Research output: Contribution to journal › Review article › peer-review

    Open Access

  • Identification of immune cell markers associated with ulcerative colitis histological disease activity in colonic biopsies

    Lefevre, P. L. C., Wang, Z., Teft, W., Zou, G., Van Viegen, T., Linggi, B., Jairath, V., Feagan, B. G., Pai, R. K. & Vande Casteele, N., 2024, (Accepted/In press) In: Journal of clinical pathology. jcp-2023-209327.

    Research output: Contribution to journal › Article › peer-review

  • Observational and genetic associations between cardiorespiratory fitness and cancer: a UK Biobank and international consortia study

    Watts, E. L., Gonzales, T. I., Strain, T., Saint-Maurice, P. F., Bishop, D. T., Chanock, S. J., Johansson, M., Keku, T. O., Le Marchand, L., Moreno, V., Newcomb, P. A., Newton, C. C., Pai, R. K., Purdue, M. P., Ulrich, C. M., Smith-Byrne, K., Van Guelpen, B., Eeles, R. A., Haiman, C. A., Kote-Jarai, Z., & 74 othersSchumacher, F. R., Benlloch, S., Olama, A. A. A., Muir, K. R., Berndt, S. I., Conti, D. V., Wiklund, F., Chanock, S. J., Wang, Y., Tangen, C. M., Batra, J., Clements, J. A., Grönberg, H., Pashayan, N., Schleutker, J., Albanes, D., Weinstein, S. J., Wolk, A., West, C. M. L., Mucci, L. A., Cancel-Tassin, G., Koutros, S., Sørensen, K. D., Grindedal, E. M., Neal, D. E., Hamdy, F. C., Donovan, J. L., Travis, R. C., Hamilton, R. J., Ingles, S. A., Rosenstein, B. S., Lu, Y. J., Giles, G. G., MacInnis, R. J., Kibel, A. S., Vega, A., Kogevinas, M., Penney, K. L., Park, J. Y., Stanford, J. L., Cybulski, C., Nordestgaard, B. G., Nielsen, S. F., Brenner, H., Maier, C., Kim, J., John, E. M., Teixeira, M. R., Neuhausen, S. L., De Ruyck, K., Razack, A., Newcomb, L. F., Lessel, D., Kaneva, R., Usmani, N., Claessens, F., Townsend, P. A., Castelao, J. E., Roobol, M. J., Menegaux, F., Khaw, K. T., Cannon-Albright, L., Pandha, H., Thibodeau, S. N., Hunter, D. J., Kraft, P., Blot, W. J., Riboli, E., Day, F. R., Wijndaele, K., Wareham, N. J., Matthews, C. E., Moore, S. C. & Brage, S., Jan 31 2024, In: British journal of cancer. 130, 1, p. 114-124 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Reliability and Responsiveness of Histologic Indices for the Assessment of Crohn's Disease Activity

    Solitano, V., Schaeffer, D. F., Hogan, M., Vande Casteele, N., Pai, R. K., Zou, G., Pai, R. K., Parker, C. E., Rémillard, J., Christensen, B., Danese, S., Peyrin-Biroulet, L., Panaccione, R., Sands, B. E., D'Haens, G., Feagan, B. G., Ma, C. & Jairath, V., 2024, (Accepted/In press) In: Clinical Gastroenterology and Hepatology.

    Research output: Contribution to journal › Article › peer-review

  • Standardizing Randomized Controlled Trials in Celiac Disease: An International Multidisciplinary Appropriateness Study

    Lebwohl, B., Ma, C., Lagana, S. M., Pai, R. K., Baker, K. A., Zayadi, A., Hogan, M., Bouma, G., Cellier, C., Goldsmith, J. D., Lundin, K. E. A., Pinto-Sanchez, M. I., Robert, M. E., Rubio-Tapia, A., Sanders, D. S., Schaeffer, D. F., Semrad, C. E., Silvester, J. A., Verdú, E. F., Verma, R., & 5 othersWu, T. T., Feagan, B. G., Crowley, E., Jairath, V. & Murray, J. A., Jan 2024, In: Gastroenterology. 166, 1, p. 88-102 15 p.

    Research output: Contribution to journal › Article › peer-review

  • 2023

    A Genetic Locus within the FMN1/GREM1 Gene Region Interacts with Body Mass Index in Colorectal Cancer Risk

    Aglago, E. K., Kim, A., Lin, Y., Qu, C., Evangelou, M., Ren, Y., Morrison, J., Albanes, D., Arndt, V., Barry, E. L., Baurley, J. W., Berndt, S. I., Bien, S. A., Bishop, D. T., Bouras, E., Brenner, H., Buchanan, D. D., Budiarto, A., Carreras-Torres, R., Casey, G., & 85 othersCenggoro, T. W., Chan, A. T., Chang-Claude, J., Chen, X., Conti, D. V., Devall, M., Diez-Obrero, V., Dimou, N., Drew, D., Figueiredo, J. C., Gallinger, S., Giles, G. G., Gruber, S. B., Gsur, A., Gunter, M. J., Hampel, H., Harlid, S., Hidaka, A., Harrison, T. A., Hoffmeister, M., Huyghe, J. R., Jenkins, M. A., Jordahl, K., Joshi, A. D., Kawaguchi, E. S., Keku, T. O., Kundaje, A., Larsson, S. C., Le Marchand, L., Lewinger, J. P., Li, L., Lynch, B. M., Mahesworo, B., Mandic, M., Obón-Santacana, M., Moreno, V., Murphy, N., Nan, H., Nassir, R., Newcomb, P. A., Ogino, S., Ose, J., Pai, R. K., Palmer, J. R., Papadimitriou, N., Pardamean, B., Peoples, A. R., Platz, E. A., Potter, J. D., Prentice, R. L., Rennert, G., Ruiz-Narvaez, E., Sakoda, L. C., Scacheri, P. C., Schmit, S. L., Schoen, R. E., Shcherbina, A., Slattery, M. L., Stern, M. C., Su, Y. R., Tangen, C. M., Thibodeau, S. N., Thomas, D. C., Tian, Y., Ulrich, C. M., van Duijnhoven, F. J. B., Van Guelpen, B., Visvanathan, K., Vodicka, P., Wang, J., White, E., Wolk, A., Woods, M. O., Wu, A. H., Zemlianskaia, N., Hsu, L., Gauderman, W. J., Peters, U., Tsilidis, K. K., Campbell, P. T., Hsu, L., Gauderman, W. J., Peters, U., Tsilidis, K. K. & Campbell, P. T., Aug 1 2023, In: Cancer research. 83, 15, p. 2572-2583 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • A Highly Sensitive Pan-Cancer Test for Microsatellite Instability

    Bacher, J. W., Udho, E. B., Strauss, E. E., Vyazunova, I., Gallinger, S., Buchanan, D. D., Pai, R. K., Templeton, A. S., Storts, D. R., Eshleman, J. R. & Halberg, R. B., Nov 2023, In: Journal of Molecular Diagnostics. 25, 11, p. 806-826 21 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Author Correction: Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries (Nature Genetics, (2023), 55, 1, (89-99), 10.1038/s41588-022-01222-9)

    Fernandez-Rozadilla, C., Timofeeva, M., Chen, Z., Law, P., Thomas, M., Schmit, S., Díez-Obrero, V., Hsu, L., Fernandez-Tajes, J., Palles, C., Sherwood, K., Briggs, S., Svinti, V., Donnelly, K., Farrington, S., Blackmur, J., Vaughan-Shaw, P., Shu, X. O., Long, J., Cai, Q., & 190 othersGuo, X., Lu, Y., Broderick, P., Studd, J., Huyghe, J., Harrison, T., Conti, D., Dampier, C., Devall, M., Schumacher, F., Melas, M., Rennert, G., Obón-Santacana, M., Martín-Sánchez, V., Moratalla-Navarro, F., Oh, J. H., Kim, J., Jee, S. H., Jung, K. J., Kweon, S. S., Shin, M. H., Shin, A., Ahn, Y. O., Kim, D. H., Oze, I., Wen, W., Matsuo, K., Matsuda, K., Tanikawa, C., Ren, Z., Gao, Y. T., Jia, W. H., Hopper, J., Jenkins, M., Win, A. K., Pai, R., Figueiredo, J., Haile, R., Gallinger, S., Woods, M., Newcomb, P., Duggan, D., Cheadle, J., Kaplan, R., Maughan, T., Kerr, R., Kerr, D., Kirac, I., Böhm, J., Mecklin, L. P., Jousilahti, P., Knekt, P., Aaltonen, L., Rissanen, H., Pukkala, E., Eriksson, J., Cajuso, T., Hänninen, U., Kondelin, J., Palin, K., Tanskanen, T., Renkonen-Sinisalo, L., Zanke, B., Männistö, S., Albanes, D., Weinstein, S., Ruiz-Narvaez, E., Palmer, J., Buchanan, D., Platz, E., Visvanathan, K., Ulrich, C., Siegel, E., Brezina, S., Gsur, A., Campbell, P., Chang-Claude, J., Hoffmeister, M., Brenner, H., Slattery, M., Potter, J., Tsilidis, K., Schulze, M., Gunter, M., Murphy, N., Castells, A., Castellví-Bel, S., Moreira, L., Arndt, V., Shcherbina, A., Stern, M., Pardamean, B., Bishop, T., Giles, G., Southey, M., Idos, G., McDonnell, K., Abu-Ful, Z., Greenson, J., Shulman, K., Lejbkowicz, F., Offit, K., Su, Y. R., Steinfelder, R., Keku, T., van Guelpen, B., Hudson, T., Hampel, H., Pearlman, R., Berndt, S., Hayes, R., Martinez, M. E., Thomas, S., Corley, D., Pharoah, P., Larsson, S., Yen, Y., Lenz, H. J., White, E., Li, L., Doheny, K., Pugh, E., Shelford, T., Chan, A., Cruz-Correa, M., Lindblom, A., Hunter, D., Joshi, A., Schafmayer, C., Scacheri, P., Kundaje, A., Nickerson, D., Schoen, R., Hampe, J., Stadler, Z., Vodicka, P., Vodickova, L., Vymetalkova, V., Papadopoulos, N., Edlund, C., Gauderman, W., Thomas, D., Shibata, D., Toland, A., Markowitz, S., Kim, A., Chanock, S., van Duijnhoven, F., Feskens, E., Sakoda, L., Gago-Dominguez, M., Wolk, A., Naccarati, A., Pardini, B., FitzGerald, L., Lee, S. C., Ogino, S., Bien, S., Kooperberg, C., Li, C., Lin, Y., Prentice, R., Qu, C., Bézieau, S., Tangen, C., Mardis, E., Yamaji, T., Sawada, N., Iwasaki, M., Haiman, C., Le Marchand, L., Wu, A., Qu, C., McNeil, C., Coetzee, G., Hayward, C., Deary, I., Harris, S., Theodoratou, E., Reid, S., Walker, M., Ooi, L. Y., Moreno, V., Casey, G., Gruber, S., Tomlinson, I., Zheng, W., Dunlop, M., Houlston, R. & Peters, U., Mar 2023, In: Nature Genetics. 55, 3, p. 519-520 2 p.

    Research output: Contribution to journal › Comment/debate › peer-review

    Open Access

  • Beyond Neutrophils for Predicting Relapse and Remission in Ulcerative Colitis

    El-Zimaity, H., Shaffer, S. R., Riddell, R. H., Pai, R. K. & Bernstein, C. N., May 1 2023, In: Journal of Crohn's and Colitis. 17, 5, p. 767-776 10 p.

    Research output: Contribution to journal › Article › peer-review

  • Combining Asian and European genome-wide association studies of colorectal cancer improves risk prediction across racial and ethnic populations

    Thomas, M., Su, Y. R., Rosenthal, E. A., Sakoda, L. C., Schmit, S. L., Timofeeva, M. N., Chen, Z., Fernandez-Rozadilla, C., Law, P. J., Murphy, N., Carreras-Torres, R., Diez-Obrero, V., van Duijnhoven, F. J. B., Jiang, S., Shin, A., Wolk, A., Phipps, A. I., Burnett-Hartman, A., Gsur, A., Chan, A. T., & 109 othersZauber, A. G., Wu, A. H., Lindblom, A., Um, C. Y., Tangen, C. M., Gignoux, C., Newton, C., Haiman, C. A., Qu, C., Bishop, D. T., Buchanan, D. D., Crosslin, D. R., Conti, D. V., Kim, D. H., Hauser, E., White, E., Siegel, E., Schumacher, F. R., Rennert, G., Giles, G. G., Hampel, H., Brenner, H., Oze, I., Oh, J. H., Lee, J. K., Schneider, J. L., Chang-Claude, J., Kim, J., Huyghe, J. R., Zheng, J., Hampe, J., Greenson, J., Hopper, J. L., Palmer, J. R., Visvanathan, K., Matsuo, K., Matsuda, K., Jung, K. J., Li, L., Le Marchand, L., Vodickova, L., Bujanda, L., Gunter, M. J., Matejcic, M., Jenkins, M. A., Slattery, M. L., D’Amato, M., Wang, M., Hoffmeister, M., Woods, M. O., Kim, M., Song, M., Iwasaki, M., Du, M., Udaltsova, N., Sawada, N., Vodicka, P., Campbell, P. T., Newcomb, P. A., Cai, Q., Pearlman, R., Pai, R. K., Schoen, R. E., Steinfelder, R. S., Haile, R. W., Vandenputtelaar, R., Prentice, R. L., Küry, S., Castellví-Bel, S., Tsugane, S., Berndt, S. I., Lee, S. C., Brezina, S., Weinstein, S. J., Chanock, S. J., Jee, S. H., Kweon, S. S., Vadaparampil, S., Harrison, T. A., Yamaji, T., Keku, T. O., Vymetalkova, V., Arndt, V., Jia, W. H., Shu, X. O., Lin, Y., Ahn, Y. O., Stadler, Z. K., Van Guelpen, B., Ulrich, C. M., Platz, E. A., Potter, J. D., Li, C. I., Meester, R., Moreno, V., Figueiredo, J. C., Casey, G., Lansdorp Vogelaar, I., Dunlop, M. G., Gruber, S. B., Hayes, R. B., Pharoah, P. D. P., Houlston, R. S., Jarvik, G. P., Tomlinson, I. P., Zheng, W., Corley, D. A., Peters, U. & Hsu, L., Dec 2023, In: Nature communications. 14, 1, 6147.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries

    Fernandez-Rozadilla, C., Timofeeva, M., Chen, Z., Law, P., Thomas, M., Schmit, S., Díez-Obrero, V., Hsu, L., Fernandez-Tajes, J., Palles, C., Sherwood, K., Briggs, S., Svinti, V., Donnelly, K., Farrington, S., Blackmur, J., Vaughan-Shaw, P., Shu, X. O., Long, J., Cai, Q., & 190 othersGuo, X., Lu, Y., Broderick, P., Studd, J., Huyghe, J., Harrison, T., Conti, D., Dampier, C., Devall, M., Schumacher, F., Melas, M., Rennert, G., Obón-Santacana, M., Martín-Sánchez, V., Moratalla-Navarro, F., Oh, J. H., Kim, J., Jee, S. H., Jung, K. J., Kweon, S. S., Shin, M. H., Shin, A., Ahn, Y. O., Kim, D. H., Oze, I., Wen, W., Matsuo, K., Matsuda, K., Tanikawa, C., Ren, Z., Gao, Y. T., Jia, W. H., Hopper, J., Jenkins, M., Win, A. K., Pai, R., Figueiredo, J., Haile, R., Gallinger, S., Woods, M., Newcomb, P., Duggan, D., Cheadle, J., Kaplan, R., Maughan, T., Kerr, R., Kerr, D., Kirac, I., Böhm, J., Mecklin, L. P., Jousilahti, P., Knekt, P., Aaltonen, L., Rissanen, H., Pukkala, E., Eriksson, J., Cajuso, T., Hänninen, U., Kondelin, J., Palin, K., Tanskanen, T., Renkonen-Sinisalo, L., Zanke, B., Männistö, S., Albanes, D., Weinstein, S., Ruiz-Narvaez, E., Palmer, J., Buchanan, D., Platz, E., Visvanathan, K., Ulrich, C., Siegel, E., Brezina, S., Gsur, A., Campbell, P., Chang-Claude, J., Hoffmeister, M., Brenner, H., Slattery, M., Potter, J., Tsilidis, K., Schulze, M., Gunter, M., Murphy, N., Castells, A., Castellví-Bel, S., Moreira, L., Arndt, V., Shcherbina, A., Stern, M., Pardamean, B., Bishop, T., Giles, G., Southey, M., Idos, G., McDonnell, K., Abu-Ful, Z., Greenson, J., Shulman, K., Lejbkowicz, F., Offit, K., Su, Y. R., Steinfelder, R., Keku, T., van Guelpen, B., Hudson, T., Hampel, H., Pearlman, R., Berndt, S., Hayes, R., Martinez, M. E., Thomas, S., Corley, D., Pharoah, P., Larsson, S., Yen, Y., Lenz, H. J., White, E., Li, L., Doheny, K., Pugh, E., Shelford, T., Chan, A., Cruz-Correa, M., Lindblom, A., Hunter, D., Joshi, A., Schafmayer, C., Scacheri, P., Kundaje, A., Nickerson, D., Schoen, R., Hampe, J., Stadler, Z., Vodicka, P., Vodickova, L., Vymetalkova, V., Papadopoulos, N., Edlund, C., Gauderman, W., Thomas, D., Shibata, D., Toland, A., Markowitz, S., Kim, A., Chanock, S., van Duijnhoven, F., Feskens, E., Sakoda, L., Gago-Dominguez, M., Wolk, A., Naccarati, A., Pardini, B., FitzGerald, L., Lee, S. C., Ogino, S., Bien, S., Kooperberg, C., Li, C., Lin, Y., Prentice, R., Qu, C., Bézieau, S., Tangen, C., Mardis, E., Yamaji, T., Sawada, N., Iwasaki, M., Haiman, C., Le Marchand, L., Wu, A., Qu, C., McNeil, C., Coetzee, G., Hayward, C., Deary, I., Harris, S., Theodoratou, E., Reid, S., Walker, M., Ooi, L. Y., Moreno, V., Casey, G., Gruber, S., Tomlinson, I., Zheng, W., Dunlop, M., Houlston, R. & Peters, U., Jan 2023, In: Nature Genetics. 55, 1, p. 89-99 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Deep Learning and Colon Cancer Interpretation: Rise of the Machine

    McHugh, K. & Pai, R. K., Dec 2023, In: Surgical Pathology Clinics. 16, 4, p. 651-658 8 p.

    Research output: Contribution to journal › Review article › peer-review

  • DNA methylation profile in CpG-depleted regions uncovers a high-risk subtype of early-stage colorectal cancer

    Yu, H., Wang, X., Bai, L., Tang, G., Carter, K. T., Cui, J., Huang, P., Liang, L., Ding, Y., Cai, M., Huang, M., Liu, H., Cao, G., Gallinger, S., Pai, R. K., Buchanan, D. D., Win, A. K., Newcomb, P. A., Wang, J., Grady, W. M., & 1 othersLuo, Y., Jan 1 2023, In: Journal of the National Cancer Institute. 115, 1, p. 52-61 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • DNA Mismatch Repair Gene Variant Classification: Evaluating the Utility of Somatic Mutations and Mismatch Repair Deficient Colonic Crypts and Endometrial Glands

    on behalf of ANGELS Study, Oct 2023, In: Cancers. 15, 20, 4925.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Elucidating the Risk of Colorectal Cancer for Variants in Hereditary Colorectal Cancer Genes

    Gecco-Ccfr Consortium, Oct 2023, In: Gastroenterology. 165, 4, p. 1070-1076.e3

    Research output: Contribution to journal › Short survey › peer-review

    Open Access

  • Genetically proxied glucose-lowering drug target perturbation and risk of cancer: a Mendelian randomisation analysis

    The PRACTICAL Consortium, VA Million Veteran Program & APCB BioResource (Australian Prostate Cancer BioResource), Aug 2023, In: Diabetologia. 66, 8, p. 1481-1500 20 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Genome-wide Interaction Study with Smoking for Colorectal Cancer Risk Identifies Novel Genetic Loci Related to Tumor Suppression, Inflammation, and Immune Response

    Carreras-Torres, R., Kim, A. E., Lin, Y., Díez-Obrero, V., Bien, S. A., Qu, C., Wang, J., Dimou, N., Aglago, E. K., Albanes, D., Arndt, V., Baurley, J. W., Berndt, S. I., Bezieau, S., Bishop, D. T., Bouras, E., Brenner, H., Budiarto, A., Campbell, P. T., Casey, G., & 69 othersChan, A. T., Chang-Claude, J., Chen, X., Conti, D. V., Dampier, C. H., Devall, M. A. M., Drew, D. A., Figueiredo, J. C., Gallinger, S., Giles, G. G., Gruber, S. B., Gsur, A., Gunter, M. J., Harrison, T. A., Hidaka, A., Hoffmeister, M., Huyghe, J. R., Jenkins, M. A., Jordahl, K. M., Kawaguchi, E., Keku, T. O., Kundaje, A., Le Marchand, L., Lewinger, J. P., Li, L., Mahesworo, B., Morrison, J. L., Murphy, N., Nan, H., Nassir, R., Newcomb, P. A., Obon-Santacana, M., Ogino, S., Ose, J., Pai, R. K., Palmer, J. R., Papadimitriou, N., Pardamean, B., Peoples, A. R., Pharoah, P. D. P., Platz, E. A., Rennert, G., Ruiz-Narvaez, E., Sakoda, L. C., Scacheri, P. C., Schmit, S. L., Schoen, R. E., Shcherbina, A., Slattery, M. L., Stern, M. C., Su, Y. R., Tangen, C. M., Thomas, D. C., Tian, Y., Tsilidis, K. K., Ulrich, C. M., van Duijnhoven, F. J. B., Van Guelpen, B., Visvanathan, K., Vodicka, P., Cenggoro, T. W., Weinstein, S. J., White, E., Wolk, A., Woods, M. O., Hsu, L., Peters, U., Moreno, V. & Gauderman, W. J., Mar 1 2023, In: Cancer Epidemiology Biomarkers and Prevention. 32, 3, p. 315-328 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Identifying metabolic features of colorectal cancer liability using Mendelian randomization

    Bull, C., Hazelwood, E., Bell, J. A., Tan, V., Constantinescu, A. E., Borges, C., Legge, D., Burrows, K., Huyghe, J. R., Brenner, H., Castellvi-Bel, S., Chan, A. T., Kweon, S. S., Marchand, L. L., Li, L., Cheng, I., Pai, R. K., Figueiredo, J. C., Murphy, N., Gunter, M. J., & 2 othersTimpson, N. J. & Vincent, E. E., Dec 2023, In: eLife. 12, RP87894.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Molecular Characteristics of Early-Onset Colorectal Cancer According to Detailed Anatomical Locations: Comparison With Later-Onset Cases

    Ugai, T., Haruki, K., Harrison, T. A., Cao, Y., Qu, C., Chan, A. T., Campbell, P. T., Akimoto, N., Berndt, S., Brenner, H., Buchanan, D. D., Chang-Claude, J., Fujiyoshi, K., Gallinger, S. J., Gunter, M. J., Hidaka, A., Hoffmeister, M., Hsu, L., Jenkins, M. A., Milne, R. L., & 21 othersMoreno, V., Newcomb, P. A., Nishihara, R., Pai, R. K., Sakoda, L. C., Slattery, M. L., Sun, W., Amitay, E. L., Alwers, E., Thibodeau, S. N., Toland, A. E., Van Guelpen, B., Woods, M. O., Zaidi, S. H., Potter, J. D., Giannakis, M., Song, M., Nowak, J. A., Phipps, A. I., Peters, U. & Ogino, S., Apr 1 2023, In: American Journal of Gastroenterology. 118, 4, p. 712-726 15 p.

    Research output: Contribution to journal › Article › peer-review

  • Performance of an Artificial Intelligence Model for Recognition and Quantitation of Histologic Features of Eosinophilic Esophagitis on Biopsy Samples

    Ricaurte Archila, L., Smith, L., Sihvo, H. K., Koponen, V., Jenkins, S. M., O'Sullivan, D. M., Cardenas Fernandez, M. C., Wang, Y., Sivasubramaniam, P., Patil, A., Hopson, P. E., Absah, I., Ravi, K., Mounajjed, T., Dellon, E. S., Bredenoord, A. J., Pai, R., Hartley, C. P., Graham, R. P. & Moreira, R. K., Oct 2023, In: Modern Pathology. 36, 10, 100285.

    Research output: Contribution to journal › Article › peer-review

  • Probing the diabetes and colorectal cancer relationship using gene – environment interaction analyses

    Dimou, N., Kim, A. E., Flanagan, O., Murphy, N., Diez-Obrero, V., Shcherbina, A., Aglago, E. K., Bouras, E., Campbell, P. T., Casey, G., Gallinger, S., Gruber, S. B., Jenkins, M. A., Lin, Y., Moreno, V., Ruiz-Narvaez, E., Stern, M. C., Tian, Y., Tsilidis, K. K., Arndt, V., & 68 othersBarry, E. L., Baurley, J. W., Berndt, S. I., Bézieau, S., Bien, S. A., Bishop, D. T., Brenner, H., Budiarto, A., Carreras-Torres, R., Cenggoro, T. W., Chan, A. T., Chang-Claude, J., Chanock, S. J., Chen, X., Conti, D. V., Dampier, C. H., Devall, M., Drew, D. A., Figueiredo, J. C., Giles, G. G., Gsur, A., Harrison, T. A., Hidaka, A., Hoffmeister, M., Huyghe, J. R., Jordahl, K., Kawaguchi, E., Keku, T. O., Larsson, S. C., Le Marchand, L., Lewinger, J. P., Li, L., Mahesworo, B., Morrison, J., Newcomb, P. A., Newton, C. C., Obon-Santacana, M., Ose, J., Pai, R. K., Palmer, J. R., Papadimitriou, N., Pardamean, B., Peoples, A. R., Pharoah, P. D. P., Platz, E. A., Potter, J. D., Rennert, G., Scacheri, P. C., Schoen, R. E., Su, Y. R., Tangen, C. M., Thibodeau, S. N., Thomas, D. C., Ulrich, C. M., Um, C. Y., van Duijnhoven, F. J. B., Visvanathan, K., Vodicka, P., Vodickova, L., White, E., Wolk, A., Woods, M. O., Qu, C., Kundaje, A., Hsu, L., Gauderman, W. J., Gunter, M. J. & Peters, U., Aug 24 2023, In: British journal of cancer. 129, 3, p. 511-520 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Prognostic role of detailed colorectal location and tumor molecular features: analyses of 13,101 colorectal cancer patients including 2994 early-onset cases

    Ugai, T., Akimoto, N., Haruki, K., Harrison, T. A., Cao, Y., Qu, C., Chan, A. T., Campbell, P. T., Berndt, S. I., Buchanan, D. D., Cross, A. J., Diergaarde, B., Gallinger, S. J., Gunter, M. J., Harlid, S., Hidaka, A., Hoffmeister, M., Brenner, H., Chang-Claude, J., Hsu, L., & 26 othersJenkins, M. A., Lin, Y., Milne, R. L., Moreno, V., Newcomb, P. A., Nishihara, R., Obon-Santacana, M., Pai, R. K., Sakoda, L. C., Schoen, R. E., Slattery, M. L., Sun, W., Amitay, E. L., Alwers, E., Thibodeau, S. N., Toland, A. E., Van Guelpen, B., Zaidi, S. H., Potter, J. D., Meyerhardt, J. A., Giannakis, M., Song, M., Nowak, J. A., Peters, U., Phipps, A. I. & Ogino, S., Mar 2023, In: Journal of gastroenterology. 58, 3, p. 229-245 17 p.

    Research output: Contribution to journal › Article › peer-review

  • Resolving Histological Inflammation in Ulcerative Colitis With Mirikizumab in the LUCENT Induction and Maintenance Trial Programmes

    Magro, F., Pai, R. K., Kobayashi, T., Jairath, V., Rieder, F., Redondo, I., Lissoos, T., Morris, N., Shan, M., Park, M. & Peyrin-Biroulet, L., Sep 1 2023, In: Journal of Crohn's and Colitis. 17, 9, p. 1457-1470 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Separating the effects of early and later life adiposity on colorectal cancer risk: a Mendelian randomization study

    Papadimitriou, N., Bull, C. J., Jenab, M., Hughes, D. J., Bell, J. A., Sanderson, E., Timpson, N. J., Smith, G. D., Albanes, D., Campbell, P. T., Küry, S., Le Marchand, L., Ulrich, C. M., Visvanathan, K., Figueiredo, J. C., Newcomb, P. A., Pai, R. K., Peters, U., Tsilidis, K. K., Boer, J. M. A., & 5 othersVincent, E. E., Mariosa, D., Gunter, M. J., Richardson, T. G. & Murphy, N., Dec 2023, In: BMC Medicine. 21, 1, 5.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Using DEPendency of Association on the Number of Top Hits (DEPTH) as a Complementary Tool to Identify Novel Colorectal Cancer Susceptibility Loci

    Lai, J., Wong, C. K., Schmidt, D. F., Kapuscinski, M. K., Alpen, K., MacInnis, R. J., Buchanan, D. D., Win, A. K., Figueiredo, J. C., Chan, A. T., Harrison, T. A., Hoffmeister, M., White, E., Le Marchand, L., Pai, R. K., Peters, U., Hopper, J. L., Jenkins, M. A. & Makalic, E., Sep 1 2023, In: Cancer Epidemiology Biomarkers and Prevention. 32, 9, p. 1153-1159 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
  • 2022

    Associations between Glycemic Traits and Colorectal Cancer: A Mendelian Randomization Analysis

    Murphy, N., Song, M., Papadimitriou, N., Carreras-Torres, R., Langenberg, C., Martin, R. M., Tsilidis, K. K., Barroso, I., Chen, J., Frayling, T. M., Bull, C. J., Vincent, E. E., Cotterchio, M., Gruber, S. B., Pai, R. K., Newcomb, P. A., Perez-Cornago, A., Van Duijnhoven, F. J. B., Van Guelpen, B., Vodicka, P., & 5 othersWolk, A., Wu, A. H., Peters, U., Chan, A. T. & Gunter, M. J., May 1 2022, In: Journal of the National Cancer Institute. 114, 5, p. 740-752 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Beyond GWAS of Colorectal Cancer: Evidence of Interaction with Alcohol Consumption and Putative Causal Variant for the 10q24.2 Region

    Jordahl, K. M., Shcherbina, A., Kim, A. E., Su, Y. R., Lin, Y., Wang, J., Qu, C., Albanes, D., Arndt, V., Baurley, J. W., Berndt, S. I., Bien, S. A., Bishop, D. T., Bouras, E., Brenner, H., Buchanan, D. D., Budiarto, A., Campbell, P. T., Carreras-Torres, R., Casey, G., & 74 othersCenggoro, T. W., Chan, A. T., Conti, D. V., Dampier, C. H., Devall, M. A., Díez-Obrero, V., Dimou, N., Drew, D. A., Figueiredo, J. C., Gallinger, S., Giles, G. G., Gruber, S. B., Gsur, A., Gunter, M. J., Hampel, H., Harlid, S., Harrison, T. A., Hidaka, A., Hoffmeister, M., Huyghe, J. R., Jenkins, M. A., Joshi, A. D., Keku, T. O., Larsson, S. C., Le Marchand, L., Lewinger, J. P., Li, L., Mahesworo, B., Moreno, V., Morrison, J. L., Murphy, N., Nan, H., Nassir, R., Newcomb, P. A., Obon-Santacana, M., Ogino, S., Ose, J., Pai, R. K., Palmer, J. R., Papadimitriou, N., Pardamean, B., Peoples, A. R., Pharoah, P. D. P., Platz, E. A., Potter, J. D., Prentice, R. L., Rennert, G., Ruiz-Narvaez, E., Sakoda, L. C., Scacheri, P. C., Schmit, S. L., Schoen, R. E., Slattery, M. L., Stern, M. C., Tangen, C. M., Thibodeau, S. N., Thomas, D. C., Tian, Y., Tsilidis, K. K., Ulrich, C. M., van Duijnhoven, F. J. B., Van Guelpen, B., Visvanathan, K., Vodicka, P., White, E., Wolk, A., Woods, M. O., Wu, A. H., Zemlianskaia, N., Chang-Claude, J., Gauderman, W. J., Hsu, L., Kundaje, A. & Peters, U., May 2022, In: Cancer Epidemiology Biomarkers and Prevention. 31, 5, p. 1077-1089 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Cancer Risk C (CR-C), a functional genomics test is a sensitive and rapid test for germline mismatch repair deficiency

    Alim, I., Loke, J., Yam, S., Templeton, A. S., Newcomb, P., Lindor, N. M., Pai, R. K., Jenkins, M. A., Buchanan, D. D., Gallinger, S., Klugman, S. & Ostrer, H., Sep 2022, In: Genetics in Medicine. 24, 9, p. 1821-1830 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium

    The European Hereditary Tumour Group (EHTG) and the International Mismatch Repair Consortium (IMRC), Dec 2022, In: Hereditary Cancer in Clinical Practice. 20, 1, 36.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Development and technical validation of an artificial intelligence model for quantitative analysis of histopathologic features of eosinophilic esophagitis

    Archila, L. R., Smith, L., Sihvo, H. K., Westerling-Bui, T., Koponen, V., O'Sullivan, D. M., Fernandez, M. C. C., Alexander, E. E., Wang, Y., Sivasubramaniam, P., Patil, A., Hopson, P. E., Absah, I., Ravi, K., Mounajjed, T., Pai, R., Hagen, C., Hartley, C., Graham, R. P. & Moreira, R. K., Jan 2022, In: Journal of Pathology Informatics. 13, 100144.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Development and Validation of a Digital Analysis Method to Quantify CD3-immunostained T Lymphocytes in Whole Slide Images of Crohn's Disease Biopsies

    Lefèvre, P., Guizzetti, L., McKee, T. D., Zou, G., Van Viegen, T., McFarlane, S. C., Shackelton, L., Feagan, B. G., Jairath, V., Pai, R. K. & Casteele, N. V., Aug 1 2022, In: Applied Immunohistochemistry and Molecular Morphology. 30, 7, p. 486-492 7 p.

    Research output: Contribution to journal › Article › peer-review

  • Development of a core outcome set for therapeutic studies in eosinophilic esophagitis (COREOS)

    The COREOS Collaborators:, Feb 2022, In: Journal of Allergy and Clinical Immunology. 149, 2, p. 659-670 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Editorial: protecting hypoxia-inducible factor 1a and gut integrity with GB004—a promising therapeutic approach for ulcerative colitis? Authors' reply

    Danese, S., Levesque, B. G., Feagan, B. G., Jucov, A., Bhandari, B. R., Pai, R. K., Meadows, K. T., Kirby, B. J., Bruey, J. M., Olson, A., Osterhout, R., Van Biene, C., Ford, J., Aranda, R., Raghupathi, K. & Sandborn, W. J., Mar 2022, In: Alimentary Pharmacology and Therapeutics. 55, 6, p. 735-736 2 p.

    Research output: Contribution to journal › Editorial › peer-review

  • FGFR2-IIIb Expression by Immunohistochemistry Has High Specificity in Cholangiocarcinoma with FGFR2 Genomic Alterations

    Uson Junior, P. L. S., DeLeon, T. T., Bogenberger, J. M., Pai, R. K., Kosiorek, H. E., Yin, J., Ahn, D. H., Sonbol, M. B., Bekaii-Saab, T., Mansfield, A. S., Buetow, K., Gores, G. J., Smoot, R., Vasmatzis, G., Kipp, B. R., Mahipal, A., Baker, A. T., Babiker, H., Barro, O., Dumbauld, C., & 11 othersZhou, Y., Aslam, F. N., Barrett, M., Jacobs, B., Meurice, N., Arora, M., Petit, J., Elliott, N., Nagalo, B., Salomao, M. A. & Borad, M. J., Aug 2022, In: Digestive diseases and sciences. 67, 8, p. 3797-3805 9 p.

    Research output: Contribution to journal › Article › peer-review

  • Gastrointestinal stromal tumors (GISTs) arising in uncommon locations: clinicopathologic features and risk assessment of esophageal, colonic, and appendiceal GISTs

    Rare GIST Risk Stratification Group, Apr 2022, In: Modern Pathology. 35, 4, p. 554-563 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Genetically proxied therapeutic inhibition of antihypertensive drug targets and risk of common cancers: A mendelian randomization analysis

    Yarmolinsky, J., Díez-Obrero, V., Richardson, T. G., Pigeyre, M., Sjaarda, J., Paré, G., Walker, V. M., Vincent, E. E., Tan, V. Y., Obón-Santacana, M., Albanes, D., Hampe, J., Gsur, A., Hampel, H., Pai, R. K., Jenkins, M., Gallinger, S., Casey, G., Zheng, W., Amos, C. I., & 3 othersDavey Smith, G., Martin, R. M. & Moreno, V., Feb 2022, In: PLoS Medicine. 19, 2, e1003897.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Genetic Regulation of DNA Methylation Yields Novel Discoveries in GWAS of Colorectal Cancer

    Barfield, R., Huyghe, J. R., Lemire, M., Dong, X., Su, Y. R., Brezina, S., Buchanan, D. D., Figueiredo, J. C., Gallinger, S., Giannakis, M., Gsur, A., Gunter, M. J., Hampel, H., Harrison, T. A., Hopper, J. L., Hudson, T. J., Li, C. I., Moreno, V., Newcomb, P. A., Pai, R. K., & 10 othersPharoah, P. D. P., Phipps, A. I., Qu, C., Steinfelder, R. S., Sun, W., Win, A. K., Zaidi, S. H., Campbell, P. T., Peters, U. & Hsu, L., May 2022, In: Cancer Epidemiology Biomarkers and Prevention. 31, 5, p. 1068-1076 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Genetic variants associated with circulating C-reactive protein levels and colorectal cancer survival: Sex-specific and lifestyle factors specific associations

    Huang, Y., Hua, X., Labadie, J. D., Harrison, T. A., Dai, J. Y., Lindstrom, S., Lin, Y., Berndt, S. I., Buchanan, D. D., Campbell, P. T., Casey, G., Gallinger, S. J., Gunter, M. J., Hoffmeister, M., Jenkins, M. A., Sakoda, L. C., Schoen, R. E., Diergaarde, B., Slattery, M. L., White, E., & 9 othersGiles, G., Brenner, H., Chang-Claude, J., Joshi, A., Ma, W., Pai, R. K., Chan, A. T., Peters, U. & Newcomb, P. A., May 1 2022, In: International Journal of Cancer. 150, 9, p. 1447-1454 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Genome-wide association study identifies tumor anatomical site-specific risk variants for colorectal cancer survival

    Labadie, J. D., Savas, S., Harrison, T. A., Banbury, B., Huang, Y., Buchanan, D. D., Campbell, P. T., Gallinger, S. J., Giles, G. G., Gunter, M. J., Hoffmeister, M., Hsu, L., Jenkins, M. A., Lin, Y., Ogino, S., Phipps, A. I., Slattery, M. L., Steinfelder, R. S., Sun, W., Van Guelpen, B., & 8 othersHua, X., Figuieredo, J. C., Pai, R. K., Nassir, R., Qi, L., Chan, A. T., Peters, U. & Newcomb, P. A., Dec 2022, In: Scientific reports. 12, 1, 127.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • International consensus to standardise histopathological scoring for small bowel strictures in Crohn's disease

    Gordon, I. O., Bettenworth, D., Bokemeyer, A., Srivastava, A., Rosty, C., De Hertogh, G., Robert, M. E., Valasek, M. A., Mao, R., Li, J., Harpaz, N., Borralho, P., Pai, R. K., Odze, R., Feakins, R., Parker, C. E., Guizzetti, L., Nguyen, T., Shackelton, L. M., Sandborn, W. J., & 7 othersJairath, V., Baker, M., Bruining, D., Fletcher, J. G., Feagan, B. G., Pai, R. K. & Rieder, F., Mar 1 2022, In: Gut. 71, 3, p. 479-486 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Interobserver agreement of estimating the extent of intestinal metaplasia in patients with chronic atrophic gastritis

    Lerch, J. M., Pai, R. K., Brown, I., Gill, A. J., Jain, D., Kővári, B., Kushima, R., Sheahan, K., Slavik, T., Srivastava, A., Lauwers, G. Y. & Langner, C., Jun 2022, In: Virchows Archiv. 480, 6, p. 1277-1281 5 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Large-scale Integrated Analysis of Genetics and Metabolomic Data Reveals Potential Links Between Lipids and Colorectal Cancer Risk

    Shu, X., Chen, Z., Long, J., Guo, X., Yang, Y., Qu, C., Ahn, Y. O., Cai, Q., Casey, G., Gruber, S. B., Huyghe, J. R., Jee, S. H., Jenkins, M. A., Jia, W. H., Jung, K. J., Kamatani, Y., Kim, D. H., Kim, J., Kweon, S. S., Le Marchand, L., & 26 othersMatsuda, K., Matsuo, K., Newcomb, P. A., Oh, J. H., Ose, J., Oze, I., Pai, R. K., Pan, Z. Z., Pharoah, P. D. P., Playdon, M. C., Ren, Z. F., Schoen, R. E., Shin, A., Shin, M. H., Shu, X. O., Sun, X., Tangen, C. M., Tanikawa, C., Ulrich, C. M., van Duijnhoven, F. J. B., Van Guelpen, B., Wolk, A., Woods, M. O., Wu, A. H., Peters, U. & Zheng, W., Jun 2022, In: Cancer Epidemiology Biomarkers and Prevention. 31, 6, p. 1216-1226 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Measuring histologic activity in inflammatory bowel disease: Why and how

    Pai, R. K., Lauwers, G. Y. & Pai, R. K., Jan 1 2022, In: Advances in anatomic pathology. 29, 1, p. 37-47 11 p.

    Research output: Contribution to journal › Review article › peer-review

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