• 2933 Citations
  • 25 Scopus h-Index
20012020

Research output per year

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Research Output

2020

Detection of DNA mismatch repair deficient crypts in random colonoscopic biopsies identifies Lynch syndrome patients

Brand, R. E., Dudley, B., Karloski, E., Das, R., Fuhrer, K., Pai, R. K. & Pai, R. K., Jan 1 2020, (Accepted/In press) In : Familial Cancer.

Research output: Contribution to journalArticle

Editorial: histologic normalisation in ulcerative colitis

Pai, R. K., Jairath, V. & Feagan, B. G., Feb 1 2020, In : Alimentary Pharmacology and Therapeutics. 51, 3, p. 399-401 3 p.

Research output: Contribution to journalEditorial

Open Access
1 Scopus citations

Histopathology Scoring Systems of Stenosis Associated With Small Bowel Crohn's Disease: A Systematic Review

Stenosis Therapy and Anti-Fibrotic Research (STAR) Consortium, Jan 2020, In : Gastroenterology. 158, 1, p. 137-150.e1

Research output: Contribution to journalArticle

4 Scopus citations

Image Analysis of Eosinophil Peroxidase Immunohistochemistry for Diagnosis of Eosinophilic Esophagitis

Wright, B. L., Doyle, A. D., Shim, K. P., Pai, R. K., Barshow, S. M., Horsley-Silva, J. L., Luo, H., Rank, M. A., Jacobsen, E. A., Katzka, D. A., Kita, H. & Dellon, E. S., Jan 1 2020, (Accepted/In press) In : Digestive diseases and sciences.

Research output: Contribution to journalArticle

2019

An update on the morphology and molecular pathology of serrated colorectal polyps and associated carcinomas

Pai, R., Bettington, M., Srivastava, A. & Rosty, C., Jan 1 2019, In : Modern Pathology.

Research output: Contribution to journalReview article

6 Scopus citations
Open Access

Editorial: evolving histological assessment of NASH. Authors' reply

Pai, R. K., Feagan, B. G., Parker, C. E., Jairath, V. & Loomba, R., Dec 1 2019, In : Alimentary Pharmacology and Therapeutics. 50, 11-12, p. 1245-1246 2 p.

Research output: Contribution to journalEditorial

Open Access

Evaluation of optimal biopsy location for assessment of histological activity, transcriptomic and immunohistochemical analyses in patients with active Crohn’s disease

Novak, G., Stevens, T., Van Viegen, T., Bossuyt, P., Štabuc, B., Jeyarajah, J., Zou, G., Gaemers, I. C., McKee, T. D., Fu, F., Shackelton, L. M., Khanna, R., van den Brink, G. R., Sandborn, W. J., Feagan, B. G., Pai, R. K., Jairath, V., Vande Casteele, N. & D’Haens, G., Jun 2019, In : Alimentary Pharmacology and Therapeutics. 49, 11, p. 1401-1409 9 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Gastrointestinal Mastocytosis: A Potential Diagnostic Pitfall to Be Aware

Zanelli, M., Pai, R., Grazia Zorzi, M., Zizzo, M., Martino, G., Morelli, L., Parisi, A., De Marco, L., Annessi, V. & Ascani, S., Jan 1 2019, In : International Journal of Surgical Pathology.

Research output: Contribution to journalArticle

Gene expression changes accompanying the duodenal adenoma-carcinoma sequence in familial adenomatous polyposis

Thiruvengadam, S. S., O’Malley, M., Laguardia, L., Lopez, R., Wang, Z., Shadrach, B. L., Chen, Y., Li, C., Veigl, M. L., Barnholtz-Sloan, J. S., Pai, R. K., Church, J. M., Kalady, M. F., Matthew Walsh, R. & Burke, C. A., Jun 1 2019, In : Clinical and translational gastroenterology. 10, 6, e-00053.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Histologic Healing Rates of Medical Therapies for Ulcerative Colitis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Battat, R., Duijvestein, M., Guizzetti, L., Choudhary, D., Boland, B. S., Dulai, P. S., Parker, C. E., Nguyen, T. M., Singh, S., Vande Casteele, N., Pai, R. K., Feagan, B. G., Sandborn, W. J. & Jairath, V., May 1 2019, In : The American Journal of Gastroenterology. 114, 5, p. 733-745 13 p.

Research output: Contribution to journalArticle

5 Scopus citations

Prognostic Implications of Pathological Response to Neoadjuvant Chemoradiation in Pathologic Stage III Rectal Cancer

Karagkounis, G., Thai, L., Mace, A. G., Wiland, H., Pai, R. K., Steele, S. R., Church, J. M. & Kalady, M. F., Jun 1 2019, In : Annals of surgery. 269, 6, p. 1117-1123 7 p.

Research output: Contribution to journalArticle

12 Scopus citations

Standardising the interpretation of liver biopsies in non-alcoholic fatty liver disease clinical trials

Pai, R. K., Kleiner, D. E., Hart, J., Adeyi, O. A., Clouston, A. D., Behling, C. A., Jain, D., Kakar, S., Brahmania, M., Burgart, L., Batts, K. P., Valasek, M. A., Torbenson, M. S., Guindi, M., Wang, H. L., Ajmera, V., Adams, L. A., Parker, C. E., Feagan, B. G., Loomba, R. & 1 others, Jairath, V., Nov 1 2019, In : Alimentary Pharmacology and Therapeutics. 50, 10, p. 1100-1111 12 p.

Research output: Contribution to journalArticle

4 Scopus citations

What is the role of histopathology in the evaluation of disease activity in Crohn's disease?

Pai, R. & Jairath, V., Feb 1 2019, In : Best Practice and Research: Clinical Gastroenterology. 38-39, 101601.

Research output: Contribution to journalReview article

1 Scopus citations
2018

Centrilobular ductular reaction correlates with fibrosis stage and fibrosis progression in non-alcoholic steatohepatitis

Zhao, L., Westerhoff, M., Pai, R., Choi, W. T., Gao, Z. H. & Hart, J., Jan 1 2018, In : Modern Pathology. 31, 1, p. 150-159 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Colorectal carcinomas with isolated loss of PMS2 staining by immunohistochemistry

Alpert, L., Pai, R. K., Srivastava, A., McKinnon, W., Wilcox, R., Yantiss, R. K., Arcega, R., Wang, H. L., Robert, M. E., Liu, X., Pai, R. K., Zhao, L., Westerhoff, M., Hampel, H., Kupfer, S., Setia, N., Xiao, S. Y., Hart, J. & Frankel, W. L., Apr 2018, In : Archives of Pathology and Laboratory Medicine. 142, 4, p. 523-528 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Definitions of response and remission for the Robarts Histopathology Index

Pai, R., Khanna, R., D'Haens, G. R., Sandborn, W. J., Jeyarajah, J., Feagan, B. G., Vande Casteele, N. & Jairath, V., Jan 1 2018, (Accepted/In press) In : Gut.

Research output: Contribution to journalArticle

2 Scopus citations

Disease activity and mucosal healing in inflammatory bowel disease: a new role for histopathology?

Pai, R. & Geboes, K., Jan 1 2018, In : Virchows Archiv. 472, 1, p. 99-110 12 p.

Research output: Contribution to journalArticle

10 Scopus citations

DNA mismatch repair protein deficient non-neoplastic colonic crypts: a novel indicator of Lynch syndrome

Pai, R., Dudley, B., Karloski, E., Brand, R. E., O’Callaghan, N., Rosty, C., Buchanan, D. D., Jenkins, M. A., Thibodeau, S. N., French, A. J., Lindor, N. M. & Pai, R. K., Jun 8 2018, (Accepted/In press) In : Modern Pathology. p. 1-11 11 p.

Research output: Contribution to journalArticle

6 Scopus citations

Editorial: validating reliability of the eosinophilic oesophagitis histological scoring system (EOE-HSS)—an important first step. Authors’ reply

Pai, R., Bredenoord, A., Feagan, B. G. & Jairath, V., Jun 1 2018, In : Alimentary Pharmacology and Therapeutics. 47, 12, p. 1714-1715 2 p.

Research output: Contribution to journalEditorial

Gastric pyloric gland adenoma: a multicentre clinicopathological study of 67 cases

Choi, W. T., Brown, I., Ushiku, T., Yozu, M., Setia, N., Srivastava, A., Johncilla, M., Pai, R., Gill, R. M., Fukayama, M., Misdraji, J. & Lauwers, G. Y., May 1 2018, In : Histopathology. 72, 6, p. 1007-1014 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Heterogeneity in Clinical, Endoscopic, and Histologic Outcome Measures and Placebo Response Rates in Clinical Trials of Eosinophilic Esophagitis: A Systematic Review

Ma, C., van Rhijn, B. D., Jairath, V., Nguyen, T. M., Parker, C. E., Aceves, S. S., Furuta, G. T., Gupta, S. K., Katzka, D. A., Safroneeva, E., Schoepfer, A. M., Straumann, A., Spergel, J. M., Pai, R. K., Feagan, B. G., Hirano, I., Dellon, E. S. & Bredenoord, A. J., Nov 2018, In : Clinical Gastroenterology and Hepatology. 16, 11, p. 1714-1729.e3

Research output: Contribution to journalReview article

6 Scopus citations

Heterogeneity in Definitions of Efficacy and Safety Endpoints for Clinical Trials of Crohn's Disease: A Systematic Review

Ma, C., Hussein, I. M., Al-Abbar, Y. J., Panaccione, R., Fedorak, R. N., Parker, C. E., Nguyen, T. M., Khanna, R., Siegel, C. A., Peyrin-Biroulet, L., Pai, R., Vande Casteele, N., D'Haens, G. R., Sandborn, W. J., Feagan, B. G. & Jairath, V., Sep 1 2018, In : Clinical Gastroenterology and Hepatology. 16, 9, p. 1407-1419.e22

Research output: Contribution to journalReview article

19 Scopus citations
1 Scopus citations

Pathologic assessment of gastrointestinal tract and pancreatic carcinoma after neoadjuvant therapy

Pai, R. K. & Pai, R., Jan 1 2018, In : Modern Pathology. 31, 1, p. 4-23 20 p.

Research output: Contribution to journalReview article

8 Scopus citations

Reliability of histologic assessment in patients with eosinophilic oesophagitis

Warners, M. J., Ambarus, C. A., Bredenoord, A. J., Verheij, J., Lauwers, G. Y., Walsh, J. C., Katzka, D. A., Nelson, S., van Viegen, T., Furuta, G. T., Gupta, S. K., Stitt, L., Zou, G., Parker, C. E., Shackelton, L. M., D'Haens, G. R., Sandborn, W. J., Dellon, E. S., Feagan, B. G., Collins, M. H. & 2 others, Jairath, V. & Pai, R., Apr 1 2018, In : Alimentary Pharmacology and Therapeutics. 47, 7, p. 940-950 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

Responsiveness of histological disease activity indices in ulcerative colitis: A post hoc analysis using data from the TOUCHSTONE randomised controlled trial

Jairath, V., Peyrin-Biroulet, L., Zou, G., Mosli, M., Vande Casteele, N., Pai, R. K., Valasek, M. A., Marchal-Bressenot, A., Stitt, L. W., Shackelton, L. M., Khanna, R., D'Haens, G. R., Sandborn, W. J., Olson, A., Feagan, B. G. & Pai, R., Jan 1 2018, (Accepted/In press) In : Gut.

Research output: Contribution to journalArticle

10 Scopus citations

Small Intestine Neuroendocrine Tumor in a Patient With MUTYH Adenomatous Polyposis—Case Report and SEER Analysis

Weidner, T. K., Kidwell, J. T., Glasgow, A. E., Menias, C. O., Ahn, D., Pai, R., Heigh, R. I. & Mishra, N., Jan 1 2018, (Accepted/In press) In : Clinical Colorectal Cancer.

Research output: Contribution to journalArticle

Substantial Interobserver Agreement in the Diagnosis of Dysplasia in Barrett Esophagus Upon Review of a Patient's Entire Set of Biopsies

Salomao, M. A., Lam-Himlin, D. & Pai, R. K., Jan 1 2018, In : American Journal of Surgical Pathology. 42, 3, p. 376-381 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Systematic review with meta-analysis: endoscopic and histologic placebo rates in induction and maintenance trials of ulcerative colitis

Ma, C., Guizzetti, L., Panaccione, R., Fedorak, R. N., Pai, R., Parker, C. E., Nguyen, T. M., Khanna, R., Vande Casteele, N., D'Haens, G., Sandborn, W. J., Feagan, B. G. & Jairath, V., Jun 1 2018, In : Alimentary Pharmacology and Therapeutics. 47, 12, p. 1578-1596 19 p.

Research output: Contribution to journalReview article

10 Scopus citations

The emerging role of histologic disease activity assessment in ulcerative colitis.

Pai, R., Jairath, V., Vande Casteele, N., Rieder, F., Parker, C. E. & Lauwers, G. Y., Jan 1 2018, (Accepted/In press) In : Gastrointestinal Endoscopy.

Research output: Contribution to journalArticle

13 Scopus citations

The role of biopsies in the treatment of colitis: Scoring of disease activity

Pai, R. & Geboes, K., Jun 13 2018, Colitis: A Practical Approach to Colon and Ileum Biopsy Interpretation. Springer International Publishing, p. 243-250 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2017

Biopsy Specimens From Allograft Liver Contain Histologic Features of Hepatitis C Virus Infection After Virus Eradication

Whitcomb, E., Choi, W. T., Jerome, K. R., Cook, L., Landis, C., Ahn, J., Te, H. S., Esfeh, J., Hanouneh, I. A., Rayhill, S. C., Gibson, W., Plesec, T., Koo, J., Wang, H. L., Hart, J., Pai, R. K. & Westerhoff, M., Aug 2017, In : Clinical Gastroenterology and Hepatology. 15, 8, p. 1279-1285 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

Colorectal carcinomas with submucosal invasion (pT1): Analysis of histopathological and molecular factors predicting lymph node metastasis

Pai, R. K., Chen, Y., Jakubowski, M. A., Shadrach, B. L., Plesec, T. P. & Pai, R., Jan 1 2017, In : Modern Pathology. 30, 1, p. 113-122 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

Development and validation of a histological index for UC

Mosli, M. H., Feagan, B. G., Zou, G., Sandborn, W. J., D'Haens, G., Khanna, R., Shackelton, L. M., Walker, C. W., Nelson, S., Vandervoort, M. K., Frisbie, V., Samaan, M. A., Jairath, V., Driman, D. K., Geboes, K., Valasek, M. A., Pai, R., Lauwers, G. Y., Riddell, R., Stitt, L. W. & 1 others, Levesque, B. G., Jan 1 2017, In : Gut. 66, 1, p. 50-58 9 p.

Research output: Contribution to journalArticle

74 Scopus citations

Epithelial neoplasms of the colon

Pai, R., Gonzalo, D. H. & Schaeffer, D. F., Jan 1 2017, Fenoglio-Preisers Gastrointestinal Pathology, Fourth Edition. Wolters Kluwer Health, p. 855-940 86 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Histologic scoring indices for evaluation of disease activity in Crohn's disease

Novak, G., Parker, C. E., Pai, R., Macdonald, J. K., Feagan, B. G., Sandborn, W. J., D'Haens, G., Jairath, V. & Khanna, R., Jul 21 2017, In : Cochrane Database of Systematic Reviews. 2017, 7, CD012351.

Research output: Contribution to journalReview article

1 Scopus citations

Low and High Birth Weights Are Risk Factors for Nonalcoholic Fatty Liver Disease in Children

Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN), Aug 1 2017, In : Journal of Pediatrics. 187, p. 141-146.e1

Research output: Contribution to journalArticle

24 Scopus citations

Patient Sex, Reproductive Status, and Synthetic Hormone Use Associate With Histologic Severity of Nonalcoholic Steatohepatitis

Yang, J. D., Abdelmalek, M. F., Guy, C. D., Gill, R. M., Lavine, J. E., Yates, K., Klair, J., Terrault, N. A., Clark, J. M., Unalp-Arida, A., Diehl, A. M., Suzuki, A., Dasarathy, S., Dasarathy, J., Hawkins, C., McCullough, A. J., Pagadala, M., Pai, R., Sargent, R., Bashir, M. & 80 others, Buie, S., Kigongo, C., Pan, Y. P., Piercy, D., Chalasani, N., Cummings, O. W., Gawrieh, S., Ghabril, M., Marri, S., Ragozzino, L., Sandrasegaran, K., Vuppalanchi, R., King, D., Osmack, P., Siegner, J., Stewart, S., Neuschwander-Tetri, B. A., Torretta, S., Ang, B., Behling, C., Bhatt, A., Loomba, R., Middleton, M., Patton, H., Sirlin, C., Aouizerat, B., Bass, N. M., Brandman, D., Ferrell, L. D., Hameed, B., Ramos, C., Ungermann, A., Atla, P., Croft, B., Garcia, R., Garcia, S., Sheikh, M., Singh, M., Boyett, S., Carucci, L., Contos, M. J., Kraft, K., Luketic, V. A. C., Puri, P., Sanyal, A. J., Schlosser, J., Siddiqui, M. S., Wolford, B., Ackermann, S., Cooney, S., Coy, D., Gelinas, K., Kowdley, K. V., Lee, M., Pierce, T., Mooney, J., Nelson, J. E., Shaw, C., Siddique, A., Wang, C., Brunt, E. M., Fowler, K., Kleiner, D. E., Grave, G. D., Doo, E. C., Hoofnagle, J. H., Robuck, P. R., Sherker, A., Belt, P., Donithan, M., Hallinan, E., Isaacson, M., May, K. P., Miriel, L., Sternberg, A., Tonascia, J., Ünalp-Arida, A., Van Natta, M., Vaughn, I. & Wilson, L., Jan 1 2017, In : Clinical Gastroenterology and Hepatology. 15, 1, p. 127-131.e2

Research output: Contribution to journalArticle

17 Scopus citations

Randomised non-inferiority trial: 1600 mg versus 400 mg tablets of mesalazine for the treatment of mild-to-moderate ulcerative colitis

D'Haens, G. R., Sandborn, W. J., Zou, G., Stitt, L. W., Rutgeerts, P. J., Gilgen, D., Jairath, V., Hindryckx, P., Shackelton, L. M., Vandervoort, M. K., Parker, C. E., Muller, C., Pai, R., Levchenko, O., Marakhouski, Y., Horynski, M., Mikhailova, E., Kharchenko, N., Pimanov, S. & Feagan, B. G., Aug 1 2017, In : Alimentary Pharmacology and Therapeutics. 46, 3, p. 292-302 11 p.

Research output: Contribution to journalArticle

10 Scopus citations
2016

A practical approach to the evaluation of gastrointestinal tract carcinomas for lynch syndrome

Pai, R. & Pai, R. K., Jan 1 2016, In : American Journal of Surgical Pathology. 40, 4, p. e17-e34

Research output: Contribution to journalArticle

20 Scopus citations

Expression of Annexin A10 in Serrated Polyps Predicts the Development of Metachronous Serrated Polyps

Macaron, C., Lopez, R., Pai, R. & Burke, C. A., Dec 1 2016, In : Clinical and Translational Gastroenterology. 7, 12, e205.

Research output: Contribution to journalArticle

5 Scopus citations

Gastric bypass surgery is protective from high-fat diet-induced non-alcoholic fatty liver disease and hepatic endoplasmic reticulum stress

Mosinski, J. D., Pagadala, M. R., Mulya, A., Huang, H., Dan, O., Shimizu, H., Batayyah, E., Pai, R., Schauer, P. R., Brethauer, S. A. & Kirwan, J. P., Jun 1 2016, In : Acta Physiologica. 217, 2, p. 141-151 11 p.

Research output: Contribution to journalArticle

19 Scopus citations

Gastric proteins MUC5AC and TFF1 as potential diagnostic markers of colonic sessile serrated adenomas/polyps

Khaidakov, M., Lai, K. K., Roudachevski, D., Sargsyan, J., Goyne, H. E., Pai, R., Lamps, L. W. & Hagedorn, C. H., Jan 1 2016, In : American Journal of Clinical Pathology. 146, 5, p. 530-537 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Histologic scoring indices for evaluation of disease activity in Crohn's disease

Novak, G., Parker, C. E., Lacey, C., Pai, R., Feagan, B. G., Sandborn, W. J., D'Haens, G., Macdonald, J. K., Levesque, B. G., Jairath, V. & Khanna, R., Sep 8 2016, In : Cochrane Database of Systematic Reviews. 2016, 9, CD012351.

Research output: Contribution to journalArticle

13 Scopus citations

Increased parenchymal damage and steatohepatitis in Caucasian non-alcoholic fatty liver disease patients with common IL1B and IL6 polymorphisms

the NASH Clinical Research Network, Dec 1 2016, In : Alimentary Pharmacology and Therapeutics. 44, 11-12, p. 1253-1264 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Interobserver variability in intraductal papillary mucinous neoplasm subtypes and application of their mucin immunoprofiles

Kwak, H. A., Liu, X., Allende, D. S., Pai, R., Hart, J. & Xiao, S. Y., Sep 1 2016, In : Modern Pathology. 29, 9, p. 977-984 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

NPTX2 is associated with neoadjuvant therapy response in rectal cancer

Karagkounis, G., Thai, L., Devecchio, J., Gantt, G. A., Duraes, L., Pai, R. & Kalady, M. F., May 1 2016, In : Journal of Surgical Research. 202, 1, p. 112-117 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Prevalence of Helicobacter pylori in Gastric Hyperplastic Polyps

Horvath, B. & Pai, R., Dec 1 2016, In : International Journal of Surgical Pathology. 24, 8, p. 704-708 5 p.

Research output: Contribution to journalArticle

4 Scopus citations