Nilufer Ertekin-Taner, MD, PhD

  • 6155 Citations
  • 37 Scopus h-Index
19962020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

1996

New thiazolo[3,2-a] pyrimidine derivatives, synthesis and calcium antagonistic activities

Balkan, A., Tozkoparan, B., Ertan, M., Sara, Y. & Ertekin, N., Dec 1 1996, In : Bollettino Chimico Farmaceutico. 135, 11, p. 648-652 5 p.

Research output: Contribution to journalArticle

5 Scopus citations
2000

Linkage of plasma Aβ42 to a quantitative locus on chromosome 10 in late-onset Alzheimer's disease pedigrees

Ertekin-Taner, N., Graff-Radford, N., Younkin, L. H., Eckman, C., Baker, M., Adamson, J., Ronald, J., Blangero, J., Hutton, M. & Younkin, S. G., Dec 22 2000, In : Science. 290, 5500, p. 2303-2304 2 p.

Research output: Contribution to journalArticle

306 Scopus citations
2001

Heritability of plasma amyloid β in typical late-onset Alzheimer's disease pedigrees

Ertekin-Taner, N., Graff-Radford, N., Younkin, L. H., Eckman, C., Adamson, J., Schaid, D. J., Blangero, J., Hutton, M. & Younkin, S. G., Jul 18 2001, In : Genetic epidemiology. 21, 1, p. 19-30 12 p.

Research output: Contribution to journalArticle

37 Scopus citations
2003

Fine mapping of the α-T catenin gene to a quantitative trait locus on chromosome 10 in late-onset Alzheimer's disease pedigrees

Ertekin-Taner, N., Ronald, J., Asahara, H., Younkin, L., Hella, M., Jain, S., Gnida, E., Younkin, S., Fadale, D., Ohyagi, Y., Singleton, A., Scanlin, L., de Andrade, M., Petersen, R., Graff-Radford, N., Hutton, M. & Younkin, S., Dec 1 2003, In : Human molecular genetics. 12, 23, p. 3133-3143 11 p.

Research output: Contribution to journalArticle

63 Scopus citations

Live discussion: Amyloid-β degradation: The forgotten half of Alzheimer's disease

Whitaker, C., Eckman, C., Almeida, C., Feinstein, D., Atwood, C., Eckman, E., Crutcher, K., Hersh, L., Leissring, M., LaVoie, M., Ertekin-Taner, N., Shapiro, P., Takahashi, R., Yamin, R., Mansourian, S., Estus, S., Lesné, S., Turner, T. & Farris, W., Dec 2003, In : Journal of Alzheimer's Disease. 5, 6, p. 491-497 7 p.

Research output: Contribution to journalComment/debate

6 Scopus citations
2004

Genetic Variants in a Haplotype Block Spanning IDE are Significantly Associated with Plasma Aβ42 Levels and Risk for Alzheimer Disease

Ertekin-Taner, N., Allen, M., Fadale, D., Scanlin, L., Younkin, L., Petersen, R. C., Graff-Radford, N. & Younkin, S. G., Apr 22 2004, In : Human mutation. 23, 4, p. 334-342 9 p.

Research output: Contribution to journalArticle

87 Scopus citations
2005

Elevated amyloid β protein (Aβ42) and late onset Alzheimer's disease are associated with single nucleotide polymorphisms in the urokinase-type plasminogen activator gene

Ertekin-Taner, N., Roland, J., Feuk, L., Prince, J., Tucker, M., Younkin, L., Hella, M., Jain, S., Hackett, A., Scanlin, L., Kelly, J., Kihiko-Ehman, M., Neltner, M., Hersch, L., Kindy, M., Markesbery, W., Hutton, M., de Andrade, M., Petersen, R. C., Graff-Radford, N. & 3 others, Estus, S., Brookes, A. J. & Younkin, S. G., Feb 1 2005, In : Human molecular genetics. 14, 3, p. 447-460 14 p.

Research output: Contribution to journalArticle

48 Scopus citations
2007

Genetics of Alzheimer's Disease: A Centennial Review

Ertekin-Taner, N., Aug 1 2007, In : Neurologic clinics. 25, 3, p. 611-667 57 p.

Research output: Contribution to journalReview article

160 Scopus citations
2008

Plasma amyloid β protein is elevated in late-onset Alzheimer disease families

Ertekin-Taner, N., Younkin, L. H., Yager, D. M., Parfitt, F., Baker, M. C., Asthana, S., Hutton, M. L., Younkin, S. G. & Graff-Radford, N. R., Feb 2008, In : Neurology. 70, 8, p. 596-606 11 p.

Research output: Contribution to journalArticle

66 Scopus citations
2009

Development of monoclonal antibodies and quantitative ELISAs targeting insulin-degrading enzyme

Delledonne, A., Kouri, N., Reinstatler, L., Sahara, T., Li, L., Zhao, J., Dickson, D. W., Ertekin-Taner, N. & Leissring, M. A., Oct 16 2009, In : Molecular neurodegeneration. 4, 1

Research output: Contribution to journalArticle

5 Scopus citations

Genetic variation in PCDH11X is associated with susceptibility to late-onset Alzheimer's disease

Carrasquillo, M. M., Zou, F., Pankratz, V. S., Wilcox, S. L., Ma, L., Walker, L. P., Younkin, S. G., Younkin, C. S., Younkin, L. H., Bisceglio, G. D., Ertekin-Taner, N., Crook, J. E., Dickson, D. W., Petersen, R. C., Graff-Radford, N. R. & Younkin, S. G., Feb 1 2009, In : Nature Genetics. 41, 2, p. 192-198 7 p.

Research output: Contribution to journalArticle

213 Scopus citations
2010

Concordant association of Insulin Degrading Enzyme gene (IDE) Variants with IDE mRNA, Aß, and Alzheimer's disease

Carrasquillo, M. M., Belbin, O., Zou, F., Allen, M., Ertekin-Taner, N., Ansari, M., Wilcox, S. L., Kashino, M. R., Ma, L., Younkin, L. H., Younkin, S. G., Younkin, C. S., Dincman, T. A., Howard, M. E., Howell, C. C., Stanton, C. M., Watson, C. M., Crump, M., Vitart, V., Hayward, C. & 25 others, Hastie, N. D., Rudan, I., Campbell, H., Polasek, O., Brown, K., Passmore, P., Craig, D., McGuinness, B., Todd, S., Kehoe, P. G., Mann, D. M., Smith, A. D., Beaumont, H., Warden, D., Holmes, C., Heun, R., Kölsch, H., Kalsheker, N., Pankratz, V. S., Dickson, D. W., Graff-Radford, N. R., Petersen, R. C., Wright, A. F., Younkin, S. G. & Morgan, K., Jan 19 2010, In : PloS one. 5, 1, e8764.

Research output: Contribution to journalArticle

35 Scopus citations

Gene expression levels as endophenotypes in genome-wide association studies of Alzheimer disease

Zou, F., Carrasquillo, M. M., Pankratz, V. S., Belbin, O., Morgan, K., Allen, M., Wilcox, S. L., Ma, L., Walker, L. P., Kouri, N., Burgess, J. D., Younkin, L. H., Younkin, S. G., Younkin, C. S., Bisceglio, G. D., Crook, J. E., Dickson, D. W., Petersen, R. C., Graff-Radford, N., Younkin, S. G. & 1 others, Ertekin-Taner, N., Feb 2010, In : Neurology. 74, 6, p. 480-486 7 p.

Research output: Contribution to journalArticle

25 Scopus citations

Genetics of Alzheimer disease in the pre- and post-GWAS era

Ertekin-Taner, N., Mar 23 2010, In : Alzheimer's Research and Therapy. 2, 1, 3.

Research output: Contribution to journalReview article

74 Scopus citations

Genetics of Alzheimer's disease: Lessons learned in two decades

Taner, N. E., Jun 1 2010, In : Turk Noroloji Dergisi. 16, 1, p. 1-11 11 p.

Research output: Contribution to journalReview article

1 Scopus citations

Genetic variation in PCDH11X is associated with susceptibility to late onset alzheimer's disease

Carrasquillo, M. M., Zou, F., Pankratz, V. S., Wilcox, S. L., Ma, L., Walker, L. P., Younkin, C. S., Younkin, L. H., Bisceglio, G. D., Ertekin-Taner, N., Crook, J. E., Dickson, D. W., Petersen, R. C., Graff-Radford, N. R. & Younkin, S. G., Jul 8 2010, In : Hirosaki Medical Journal. 61, SUPPL., p. S125-S134

Research output: Contribution to journalArticle

Meta-analysis confirms CR1, CLU, and PICALM as Alzheimer disease risk loci and reveals interactions with APOE genotypes

Jun, G., Naj, A. C., Beecham, G. W., Wang, L. S., Buros, J., Gallins, P. J., Buxbaum, J. D., Ertekin-Taner, N., Fallin, M. D., Friedland, R., Inzelberg, R., Kramer, P., Rogaeva, E., St George-Hyslop, P., Cantwell, L. B., Dombroski, B. A., Saykin, A. J., Reiman, E. M., Bennett, D. A., Morris, J. C. & 16 others, Lunetta, K. L., Martin, E. R., Montine, T. J., Goate, A. M., Blacker, D., Tsuang, D. W., Beekly, D., Cupples, L. A., Hakonarson, H., Kukull, W., Foroud, T. M., Haines, J., Mayeux, R., Farrer, L. A., Pericak-Vance, M. A. & Schellenberg, G. D., Dec 2010, In : Archives of neurology. 67, 12, p. 1473-1484 12 p.

Research output: Contribution to journalArticle

288 Scopus citations
2011

Association of common KIBRA variants with episodic memory and AD risk

Burgess, J. D., Pedraza, O., Graff-Radford, N. R., Hirpa, M., Zou, F., Miles, R., Nguyen, T., Li, M., Lucas, J. A., Ivnik, R. J., Crook, J., Pankratz, V. S., Dickson, D. W., Petersen, R. C., Younkin, S. G. & Ertekin-Taner, N., Mar 2011, In : Neurobiology of aging. 32, 3, p. 557.e1-557.e9

Research output: Contribution to journalArticle

36 Scopus citations

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

Naj, A. C., Jun, G., Beecham, G. W., Wang, L. S., Vardarajan, B. N., Buros, J., Gallins, P. J., Buxbaum, J. D., Jarvik, G. P., Crane, P. K., Larson, E. B., Bird, T. D., Boeve, B. F., Graff-Radford, N. R., De Jager, P. L., Evans, D., Schneider, J. A., Carrasquillo, M. M., Ertekin-Taner, N., Younkin, S. G. & 135 others, Cruchaga, C., Kauwe, J. S. K., Nowotny, P., Kramer, P., Hardy, J., Huentelman, M. J., Myers, A. J., Barmada, M. M., Demirci, F. Y., Baldwin, C. T., Green, R. C., Rogaeva, E., George-Hyslop, P. S., Arnold, S. E., Barber, R., Beach, T., Bigio, E. H., Bowen, J. D., Boxer, A., Burke, J. R., Cairns, N. J., Carlson, C. S., Carney, R. M., Carroll, S. L., Chui, H. C., Clark, D. G., Corneveaux, J., Cotman, C. W., Cummings, J. L., Decarli, C., Dekosky, S. T., Diaz-Arrastia, R., Dick, M., Dickson, D. W., Ellis, W. G., Faber, K. M., Fallon, K. B., Farlow, M. R., Ferris, S., Frosch, M. P., Galasko, D. R., Ganguli, M., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Gilman, S., Giordani, B., Glass, J. D., Growdon, J. H., Hamilton, R. L., Harrell, L. E., Head, E., Honig, L. S., Hulette, C. M., Hyman, B. T., Jicha, G. A., Jin, L. W., Johnson, N., Karlawish, J., Karydas, A., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Lah, J. J., Levey, A. I., Lieberman, A. P., Lopez, O. L., MacK, W. J., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Parisi, J. E., Perl, D. P., Peskind, E., Petersen, R. C., Poon, W. W., Quinn, J. F., Rajbhandary, R. A., Raskind, M., Reisberg, B., Ringman, J. M., Roberson, E. D., Rosenberg, R. N., Sano, M., Schneider, L. S., Seeley, W., Shelanski, M. L., Slifer, M. A., Smith, C. D., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Trojanowski, J. Q., Troncoso, J. C., Van Deerlin, V. M., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Woltjer, R. L., Cantwell, L. B., Dombroski, B. A., Beekly, D., Lunetta, K. L., Martin, E. R., Kamboh, M. I., Saykin, A. J., Reiman, E. M., Bennett, D. A., Morris, J. C., Montine, T. J., Goate, A. M., Blacker, D., Tsuang, D. W., Hakonarson, H., Kukull, W. A., Foroud, T. M., Haines, J. L., Mayeux, R., Pericak-Vance, M. A., Farrer, L. A. & Schellenberg, G. D., May 1 2011, In : Nature Genetics. 43, 5, p. 436-443 8 p.

Research output: Contribution to journalArticle

1148 Scopus citations
21 Scopus citations

Novel p.Ile151Val mutation in VCP in A patient of african american descent with sporadic ALS

DeJesus-Hernandez, M., Desaro, P., Johnston, A., Ross, O. A., Wszolek, Z. K., Ertekin-Taner, N., Graff-Radford, N. R., Rademakers, R. & Boylan, K., Sep 13 2011, In : Neurology. 77, 11, p. 1102-1103 2 p.

Research output: Contribution to journalArticle

37 Scopus citations
2012

An evaluation of the impact of MAPT, SNCA and APOE on the burden of Alzheimer's and Lewy body pathology

Wider, C., Ross, O. A., Nishioka, K., Heckman, M. G., Vilariño-Güell, C., Jasinska-Myga, B., Erketin-Taner, N., Rademakers, R., Graff-Radford, N. R., Mash, D. C., Papapetropoulos, S., Duara, R., Uchikado, H., Wszolek, Z. K., Farrer, M. J. & Dickson, D. W., Apr 1 2012, In : Journal of Neurology, Neurosurgery and Psychiatry. 83, 4, p. 424-429 6 p.

Research output: Contribution to journalArticle

41 Scopus citations

Approach to the patient with dementia

Taner, N. & Graff Radford, N. R., Oct 22 2012, Practical Neurology: Fourth Edition. Wolters Kluwer Health Pharma Solutions (Europe) Ltd, p. 10-22 13 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Association and heterogeneity at the GAPDH locus in Alzheimer's disease

Allen, M., Cox, C., Belbin, O., Ma, L., Bisceglio, G. D., Wilcox, S. L., Howell, C. C., Hunter, T. A., Culley, O., Walker, L. P., Carrasquillo, M. M., Dickson, D. W., Petersen, R. C., Graff-Radford, N. R., Younkin, S. G. & Ertekin-Taner, N., Jan 2012, In : Neurobiology of aging. 33, 1, p. 203.e25-203.e33

Research output: Contribution to journalArticle

14 Scopus citations

Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants

Zou, F., Chai, H. S., Younkin, C. S., Allen, M., Crook, J., Pankratz, V. S., Carrasquillo, M. M., Rowley, C. N., Nair, A. A., Middha, S., Maharjan, S., Nguyen, T., Ma, L., Malphrus, K. G., Palusak, R., Lincoln, S., Bisceglio, G., Georgescu, C., Kouri, N., Kolbert, C. P. & 11 others, Jen, J., Haines, J. L., Mayeux, R., Pericak-Vance, M. A., Farrer, L. A., Schellenberg, G. D., Petersen, R. C., Graff-Radford, N. R., Dickson, D. W., Younkin, S. G. & Ertekin-Taner, N., Jun 1 2012, In : PLoS genetics. 8, 6, e1002707.

Research output: Contribution to journalArticle

138 Scopus citations

Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis

Whitcomb, D. C., LaRusch, J., Krasinskas, A. M., Klei, L., Smith, J. P., Brand, R. E., Neoptolemos, J. P., Lerch, M. M., Tector, M., Sandhu, B. S., Guda, N. M., Orlichenko, L., Alkaade, S., Amann, S. T., Anderson, M. A., Baillie, J., Banks, P. A., Conwell, D., Coté, G. A., Cotton, P. B. & 178 others, DiSario, J., Farrer, L. A., Forsmark, C. E., Johnstone, M., Gardner, T. B., Gelrud, A., Greenhalf, W., Haines, J. L., Hartman, D. J., Hawes, R. A., Lawrence, C., Lewis, M., Mayerle, J., Mayeux, R., Melhem, N. M., Money, M. E., Muniraj, T., Papachristou, G. I., Pericak-Vance, M. A., Romagnuolo, J., Schellenberg, G. D., Sherman, S., Simon, P., Singh, V. P., Slivka, A., Stolz, D., Sutton, R., Weiss, F. U., Wilcox, C. M., Zarnescu, N. O., Wisniewski, S. R., O'Connell, M. R., Kienholz, M. L., Roeder, K., Barmada, M. M., Yadav, D., Devlin, B., Albert, M. S., Albin, R. L., Apostolova, L. G., Arnold, S. E., Baldwin, C. T., Barber, R., Barnes, L. L., Beach, T. G., Beecham, G. W., Beekly, D., Bennett, D. A., Bigio, E. H., Bird, T. D., Blacker, D., Boxer, A., Burke, J. R., Buxbaum, J. D., Cairns, N. J., Cantwell, L. B., Cao, C., Carney, R. M., Carroll, S. L., Chui, H. C., Clark, D. G., Cribbs, D. H., Crocco, E. A., Cruchaga, C., DeCarli, C., Demirci, F. Y., Dick, M., Dickson, D. W., Duara, R., Ertekin-Taner, N., Faber, K. M., Fallon, K. B., Farlow, M. R., Ferris, S., Foroud, T. M., Frosch, M. P., Galasko, D. R., Ganguli, M., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Gilman, S., Glass, J. D., Goate, A. M., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hakonarson, H., Hamilton-Nelson, K. L., Hamilton, R. L., Harrell, L. E., Head, E., Honig, L. S., Hulette, C. M., Hyman, B. T., Jicha, G. A., Jin, L. W., Jun, G., Kamboh, M. I., Karydas, A., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, J. H., Kramer, P., Kukul, W. A., LaFerla, F. M., Lah, J. J., Leverenz, J. B., Levey, A. I., Li, G., Lin, C. F., Lieberman, A. P., Lopez, O. L., Lunetta, K. L., Lyketsos, C. G., MacK, W. J., Marson, D. C., Martin, E. R., Martiniuk, F., Mash, D. C., Masliah, E., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Montine, T. J., Morris, J. C., Murrel, J. R., Naj, A. C., Olichney, J. M., Parisi, J. E., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reiman, E. M., Reisberg, B., Reitz, C., Ringman, J. M., Roberson, E. D., Rosen, H. J., Rosenberg, R. N., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Valladares, O., Van Deerlin, V. M., Van Eldik, L. J., Vardarajan, B. N., Vinters, H. V., Vonsatte, J. P., Wang, L. S., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Woltjer, R. L., Wright, C. B., Younkin, S. G., Yu, C. E. & Yu, L., Dec 1 2012, In : Nature Genetics. 44, 12, p. 1349-1354 6 p.

Research output: Contribution to journalArticle

156 Scopus citations

Evidence for a role of the rare p.A152T variant in mapt in increasing the risk for FTD-spectrum and Alzheimer's diseases

Coppola, G., Chinnathambi, S., Lee, J. J. Y., Dombroski, B. A., Baker, M. C., Soto-ortolaza, A. I., Lee, S. E., Klein, E., Huang, A. Y., Sears, R., Lane, J. R., Karydas, A. M., Kenet, R. O., Biernat, J., Wang, L. S., Cotman, C. W., Decarli, C. S., Levey, A. I., Ringman, J. M., Mendez, M. F. & 210 others, Chui, H. C., Le ber, I., Brice, A., Lupton, M. K., Preza, E., Lovestone, S., Powell, J., Graff-radford, N., Petersen, R. C., Boeve, B. F., Lippa, C. F., Bigio, E. H., Mackenzie, I., Finger, E., Kertesz, A., Caselli, R. J., Gearing, M., Juncos, J. L., Ghetti, B., Spina, S., Bordelon, Y. M., Tourtellotte, W. W., Frosch, M. P., Vonsattel, J. P. G., Zarow, C., Beach, T. G., Albin, R. L., Lieberman, A. P., Lee, V. M., Trojanowski, J. Q., Van deerlin, V. M., Bird, T. D., Galasko, D. R., Masliah, E., White, C. L., Troncoso, J. C., Hannequin, D., Boxer, A. L., Geschwind, M. D., Kumar, S., Mandelkow, E. M., Wszolek, Z. K., Uitti, R. J., Dickson, D. W., Haines, J. L., Mayeux, R., Pericak-vance, M. A., Farrer, L. A., Apostolova, L. G., Arnold, S. E., Baldwin, C. T., Barber, R., Barmada, M. M., Beach, T., Beecham, G. W., Beekly, D., Bennett, D. A., Bigio, E. H., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Buros, J., Buxbaum, J. D., Cairns, N. J., Cantwell, L. B., Cao, C., Carlson, C. S., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Chui, H. C., Clark, D. G., Corneveaux, J., Cotman, C. W., Crane, P. K., Cruchaga, C., Cummings, J. L., De Jager, P. L., DeCarli, C., DeKosky, S. T., Demirci, F. Y., Diaz-Arrastia, R., Dick, M., Dickson, D. W., Dombroski, B. A., Duara, R., Ellis, W. G., Ertekin-Taner, N. N., Evans, D., Faber, K. M., Fallon, K. B., Farlow, M. R., Ferris, S., Foroud, T. M., Frosch, M. P., Galasko, D. R., Gallins, P. J., Ganguli, M., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Gilman, S., Giordani, B., Glass, J. D., Goate, A. M., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hakonarson, H., Hamilton, R. L., Hardy, J., Harrell, L. E., Head, E., Honig, L. S., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Johnson, N., Jun, G., Kamboh, M. I., Karlawish, J., Karydas, A., Kauwe, J. S. K., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, P., Kukull, W. A., Lah, J. J., Larson, E. B., Levey, A. I., Lieberman, A. P., Lopez, O. L., Lunetta, K. L., Mack, W. J., Marson, D. C., Martin, E. R., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Montine, T. J., Morris, J. C., Myers, A. J., Naj, A. C., Nowotny, P., Parisi, J. E., Perl, D. P., Peskind, E., Petersen, R. C., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Rajbhandary, R. A., Raskind, M., Reiman, E. M., Reisberg, B., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosenberg, R. N., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W., Shelanski, M. L., Slifer, M. A., Smith, C. D., Sonnen, J. A., Spina, S., George-Hyslop, P. S., Stern, R. A., Tanzi, R. E., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Van Deerlin, V. M., Vardarajan, B. N., Vinters, H. V., Vonsattel, J. P., Wang, L. S., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Woltjer, R. L., Younkin, S. G., Ross, O. A., Rademakers, R., Schellenberg, G. D., Miller, B. L., Mandelkow, E. & Geschwind, D. H., Aug 2012, In : Human molecular genetics. 21, 15, p. 3500-3512 13 p.

Research output: Contribution to journalArticle

139 Scopus citations

Genetic architecture of resilience of executive functioning

Mukherjee, S., Kim, S., Gibbons, L. E., Nho, K., Risacher, S. L., Glymour, M. M., Habeck, C., Lee, G. J., Mormino, E., Ertekin-Taner, N., Montine, T. J., DeCarli, C., Saykin, A. J. & Crane, P. K., Jun 19 2012, In : Brain Imaging and Behavior. 6, 4, p. 621-633 13 p.

Research output: Contribution to journalArticle

17 Scopus citations

Glutathione S-transferase omega genes in Alzheimer and Parkinson disease risk, age-at-diagnosis and brain gene expression: An association study with mechanistic implications

Allen, M., Zou, F., Chai, H. S., Younkin, C. S., Miles, R., Nair, A. A., Crook, J. E., Pankratz, V. S., Carrasquillo, M. M., Rowley, C. N., Nguyen, T., Ma, L., Malphrus, K. G., Bisceglio, G., Ortolaza, A. I., Palusak, R., Middha, S., Maharjan, S., Georgescu, C., Schultz, D. & 14 others, Rakhshan, F., Kolbert, C. P., Jen, J., Sando, S. B., Aasly, J. O., Barcikowska, M., Uitti, R. J., Wszolek, Z. K., Ross, O. A., Petersen, R. C., Graff-Radford, N. R., Dickson, D. W., Younkin, S. G. & Ertekin-Taner, N., Apr 12 2012, In : Molecular neurodegeneration. 7, 1, 13.

Research output: Contribution to journalArticle

45 Scopus citations

Novel late-onset Alzheimer disease loci variants associate with brain gene expression

Allen, M., Zou, F., Chai, H. S., Younkin, C. S., Crook, J., Pankratz, V. S., Carrasquillo, M. M., Rowley, C. N., Nair, A. A., Middha, S., Maharjan, S., Nguyen, T., Ma, L., Malphrus, K. G., Palusak, R., Lincoln, S., Bisceglio, G., Georgescu, C., Schultz, D., Rakhshan, F. & 12 others, Kolbert, C. P., Jen, J., Haines, J. L., Mayeux, R., Pericak-Vance, M. A., Farrer, L. A., Schellenberg, G. D., Petersen, R. C., Graff-Radford, N. R., Dickson, D. W., Younkin, S. G. & Ertekin-Taner, N., Jul 17 2012, In : Neurology. 79, 3, p. 221-228 8 p.

Research output: Contribution to journalArticle

91 Scopus citations
2013

Alzheimer disease: The quest for Alzheimer disease genes-focus on CSF tau

Ertekin-Taner, N., Jul 1 2013, In : Nature Reviews Neurology. 9, 7, p. 368-370 3 p.

Research output: Contribution to journalShort survey

5 Scopus citations

DNMT1 mutation hot spot causes varied phenotypes of HSAN1 with dementia and hearing loss

Klein, C. J., Bird, T., Ertekin-Taner, N., Lincoln, S., Hjorth, R., Wu, Y., Kwok, J., Mer, G., Dyck, P. J. & Nicholson, G. A., Feb 26 2013, In : Neurology. 80, 9, p. 824-828 5 p.

Research output: Contribution to journalArticle

35 Scopus citations

LRRTM3 Interacts with APP and BACE1 and Has Variants Associating with Late-Onset Alzheimer's Disease (LOAD)

Lincoln, S., Allen, M., Cox, C. L., Walker, L. P., Malphrus, K., Qiu, Y., Nguyen, T., Rowley, C., Kouri, N., Crook, J., Pankratz, V. S., Younkin, S., Younkin, L., Carrasquillo, M., Zou, F., Abdul-Hay, S. O., Springer, W., Sando, S. B., Aasly, J. O., Barcikowska, M. & 8 others, Wszolek, Z. K., Lewis, J. M., Dickson, D., Graff-Radford, N. R., Petersen, R. C., Eckman, E., Younkin, S. G. & Ertekin-Taner, N., Jun 4 2013, In : PloS one. 8, 6, e64164.

Research output: Contribution to journalArticle

7 Scopus citations

Other genes implicated in Alzheimer's disease

Carrasquillo, M. M., Allen, M. & Taner, N., Apr 1 2013, Genetic variants in Alzheimer's disease. Springer New York, p. 209-230 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

TMEM106B p.T185S regulates TMEM106B protein levels: Implications for frontotemporal dementia

Nicholson, A. M., Finch, N. A., Wojtas, A., Baker, M. C., Perkerson, R. B., Castanedes-Casey, M., Rousseau, L., Benussi, L., Binetti, G., Ghidoni, R., Hsiung, G. Y. R., Mackenzie, I. R., Finger, E., Boeve, B. F., Ertekin-Taner, N., Graff-Radford, N. R., Dickson, D. W. & Rademakers, R., Sep 1 2013, In : Journal of neurochemistry. 126, 6, p. 781-791 11 p.

Research output: Contribution to journalArticle

44 Scopus citations

TREM2 in neurodegeneration: Evidence for association of the p.R47H variant with frontotemporal dementia and Parkinson's disease

Rayaprolu, S., Mullen, B., Baker, M., Lynch, T., Finger, E., Seeley, W. W., Hatanpaa, K. J., Lomen-Hoerth, C., Kertesz, A., Bigio, E. H., Lippa, C., Josephs, K. A., Knopman, D. S., White, C. L., Caselli, R., Mackenzie, I. R., Miller, B. L., Boczarska-Jedynak, M., Opala, G., Krygowska-Wajs, A. & 13 others, Barcikowska, M., Younkin, S. G., Petersen, R. C., Ertekin-Taner, N., Uitti, R. J., Meschia, J. F., Boylan, K. B., Boeve, B. F., Graff-Radford, N. R., Wszolek, Z. K., Dickson, D. W., Rademakers, R. & Ross, O. A., Jun 25 2013, In : Molecular neurodegeneration. 8, 1, 19.

Research output: Contribution to journalArticle

201 Scopus citations

Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein e ε4, and the risk of late-onset Alzheimer disease in African Americans

Reitz, C., Jun, G., Naj, A., Rajbhandary, R., Vardarajan, B. N., Wang, L. S., Valladares, O., Lin, C. F., Larson, E. B., Graff-Radford, N. R., Evans, D., De Jager, P. L., Crane, P. K., Buxbaum, J. D., Murrell, J. R., Raj, T., Ertekin-Taner, N., Logue, M., Baldwin, C. T., Green, R. C. & 22 others, Barnes, L. L., Cantwell, L. B., Fallin, M. D., Go, R. C. P., Griffith, P., Obisesan, T. O., Manly, J. J., Lunetta, K. L., Kamboh, M. I., Lopez, O. L., Bennett, D. A., Hendrie, H., Hall, K. S., Goate, A. M., Byrd, G. S., Kukull, W. A., Foroud, T. M., Haines, J. L., Farrer, L. A., Pericak-Vance, M. A., Schellenberg, G. D. & Mayeux, R., Apr 10 2013, In : JAMA - Journal of the American Medical Association. 309, 14, p. 1483-1492 10 p.

Research output: Contribution to journalArticle

202 Scopus citations
2014

ALS-FTD complex disorder due to C9ORF72 gene mutation: Description of first polish family

Siuda, J., Lewicka, T., Bujak, M., Opala, G., Golenia, A., Slowik, A., Van Blitterswijk, M., Baker, M., Ertekin-Taner, N., Wszolek, Z. K. & Rademakers, R., Jul 2014, In : European Neurology. 72, 1-2, p. 64-71 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Alzheimer's disease: Early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci

De Jager, P. L., Srivastava, G., Lunnon, K., Burgess, J., Schalkwyk, L. C., Yu, L., Eaton, M. L., Keenan, B. T., Ernst, J., McCabe, C., Tang, A., Raj, T., Replogle, J., Brodeur, W., Gabriel, S., Chai, H. S., Younkin, C., Younkin, S. G., Zou, F., Szyf, M. & 9 others, Epstein, C. B., Schneider, J. A., Bernstein, B. E., Meissner, A., Ertekin-Taner, N., Chibnik, L. B., Kellis, M., Mill, J. & Bennett, D. A., Sep 1 2014, In : Nature Neuroscience. 17, 9, p. 1156-1163 8 p.

Research output: Contribution to journalArticle

379 Scopus citations

ApoE variant p.V236E is associated with markedly reduced risk of Alzheimer's disease

Medway, C. W., Abdul-Hay, S., Mims, T., Ma, L., Bisceglio, G., Zou, F., Pankratz, S., Sando, S. B., Aasly, J. O., Barcikowska, M., Siuda, J., Wszolek, Z. K., Ross, O. A., Carrasquillo, M., Dickson, D. W., Graff-Radford, N., Petersen, R. C., Ertekin-Taner, N., Morgan, K., Bu, G. & 1 others, Younkin, S. G., Mar 10 2014, In : Molecular neurodegeneration. 9, 1, 11.

Research output: Contribution to journalArticle

19 Scopus citations

Association of MAPT haplotypes with Alzheimer's disease risk and MAPT brain gene expression levels

Allen, M., Kachadoorian, M., Quicksall, Z., Zou, F., Chai, H. S., Younkin, C., Crook, J. E., Pankratz, V. S., Carrasquillo, M. M., Krishnan, S., Nguyen, T., Ma, L., Malphrus, K., Lincoln, S., Bisceglio, G., Kolbert, C. P., Jen, J., Mukherjee, S., Kauwe, J. K., Crane, P. K. & 11 others, Haines, J. L., Mayeux, R., Pericak-Vance, M. A., Farrer, L. A., Schellenberg, G. D., Parisi, J. E., Petersen, R. C., Graff-Radford, N. R., Dickson, D. W., Younkin, S. G. & Ertekin-Taner, N., Jul 1 2014, In : Alzheimer's Research and Therapy. 6, 4, 39.

Research output: Contribution to journalArticle

55 Scopus citations

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: A genome-wide association study

Alzheimer Disease Genetics Consortium, Nov 1 2014, In : JAMA neurology. 71, 11, p. 1394-1404 11 p.

Research output: Contribution to journalArticle

93 Scopus citations

Evaluation of memory endophenotypes for association with CLU, CR1, and PICALM variants in black and white subjects

Pedraza, O., Allen, M., Jennette, K., Carrasquillo, M., Crook, J., Serie, D., Pankratz, V. S., Palusak, R., Nguyen, T., Malphrus, K., Ma, L., Bisceglio, G., Roberts, R. O., Lucas, J. A., Ivnik, R. J., Smith, G. E., Graff-Radford, N. R., Petersen, R. C., Younkin, S. G. & Ertekin-Taner, N., Mar 2014, In : Alzheimer's and Dementia. 10, 2, p. 205-213 9 p.

Research output: Contribution to journalArticle

29 Scopus citations

Gene-based GWAS and biological pathway analysis of the resilience of executive functioning

Mukherjee, S., Kim, S., Ramanan, V. K., Gibbons, L. E., Nho, K., Glymour, M. M., Ertekin-Taner, N., Montine, T. J., Saykin, A. J. & Crane, P. K., Feb 25 2014, In : Brain Imaging and Behavior. 8, 1, p. 110-118 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

Genome-wide association interaction analysis for Alzheimer's disease

GERAD1 Consortium, Nov 1 2014, In : Neurobiology of aging. 35, 11, p. 2436-2443 8 p.

Research output: Contribution to journalArticle

38 Scopus citations

Late-onset Alzheimer disease genetic variants in posterior cortical atrophy and posterior AD

Carrasquillo, M. M., Khan, Q. U. A., Murray, M. E., Krishnan, S., Aakre, J., Pankratz, V. S., Nguyen, T., Ma, L., Bisceglio, G., Petersen, R. C., Younkin, S. G., Dickson, D. W., Boeve, B. F., Graff-Radford, N. R. & Ertekin-Taner, N., Apr 22 2014, In : Neurology. 82, 16, p. 1455-1462 8 p.

Research output: Contribution to journalArticle

34 Scopus citations

Two rare AKAP9 variants are associated with Alzheimer's disease in African Americans

Logue, M. W., Schu, M., Vardarajan, B. N., Farrell, J., Bennett, D. A., Buxbaum, J. D., Byrd, G. S., Taner, N., Evans, D., Foroud, T., Goate, A., Graff Radford, N. R., Kamboh, M. I., Kukull, W. A., Manly, J. J., Hainesm, J. L., Mayeuxl, R., Pericak-Vancen, M. A., Schellenbergo, G. D., Lunettab, K. L. & 3 others, Baldwina, C. T., Daniele Fallinp, M. & Farrer, L. A., 2014, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

52 Scopus citations
2015

Association of long runs of homozygosity with Alzheimer disease among African American individuals

Ghani, M., Reitz, C., Cheng, R., Vardarajan, B. N., Jun, G., Sato, C., Naj, A., Rajbhandary, R., Wang, L. S., Valladares, O., Lin, C. F., Larson, E. B., Graff-Radford, N. R., Evans, D., De Jager, P. L., Crane, P. K., Buxbaum, J. D., Murrell, J. R., Raj, T., Ertekin-Taner, N. & 153 others, Logue, M., Baldwin, C. T., Green, R. C., Barnes, L. L., Cantwell, L. B., Fallin, M. D., Go, R. C. P., Griffith, P. A., Obisesan, T. O., Manly, J. J., Lunetta, K. L., Kamboh, M. I., Lopez, O. L., Bennett, D. A., Hendrie, H., Hall, K. S., Goate, A. M., Byrd, G. S., Kukull, W. A., Foroud, T. M., Haines, J. L., Farrer, L. A., Pericak-Vance, M. A., Lee, J. H., Schellenberg, G. D., St. George-Hyslop, P., Mayeux, R., Rogaeva, E., Albert, M. S., Albin, R. L., Apostolova, L. G., Arnold, S. E., Barber, R., Barmada, M. M., Beach, T. G., Beecham, G. W., Beekly, D., Bigio, E. H., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Cai, G., Cairns, N. J., Cao, C., Carlson, C. S., Carney, R. M., Carroll, S. L., Chui, H. C., Clark, D. G., Cribbs, D. H., Crocco, E. A., Cruchaga, C., DeCarli, C., DeKosky, S. T., Demirci, F. Y., Dick, M., Faber, K. M., Fallon, K. B., Ferris, S., Frosch, M. P., Galasko, D. R., Ganguli, M., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Gilman, S., Glass, J. D., Growdon, J. H., Hakonarson, H., Hamilton, R. L., Hamilton-Nelson, K. L., Haroutunian, V., Harrell, L. E., Honig, L. S., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Karydas, A., Kauwe, J. S. K., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, J. H., Kramer, P., LaFerla, F. M., Lah, J. J., Lang-Walker, R., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lyketsos, C. G., Mack, W. J., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Montine, T. J., Morris, J. C., Olichney, J. M., Parisi, J. E., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reiman, E. M., Reisberg, B., Ringman, J. M., Roberson, E. D., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Van Deerlin, V. M., Van Eldik, L. J., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Woltjer, R. L., Wright, C. B., Younkin, S. G., Yu, C. E. & Yu, L., Nov 2015, In : JAMA neurology. 72, 11, p. 1313-1323 11 p.

Research output: Contribution to journalArticle

18 Scopus citations

Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study

Alzheimer’s Disease Genetics Consortium, The GERAD1 Consortium & EPIC-InterAct Consortium, Jun 1 2015, In : PLoS Medicine. 12, 6, e1001841.

Research output: Contribution to journalArticle

69 Scopus citations

Genetically predicted body mass index and Alzheimer's disease-related phenotypes in three large samples: Mendelian randomization analyses

Adult Changes in Thought Study Investigators, Religious Orders Study/Memory and Aging Project Investigators & Alzheimer's Disease Genetics Consortium, Dec 1 2015, In : Alzheimer's and Dementia. 11, 12, p. 1439-1451 13 p.

Research output: Contribution to journalArticle

22 Scopus citations