• 14729 Citations
  • 67 Scopus h-Index
1987 …2020
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Research Output 1987 2019

2019
1 Citation (Scopus)

An empiric analysis of 5 counter measures against surgical site infections following spine surgery—a pragmatic approach and review of the literature

Tomov, M., Wanderman, N., Berbari, E., Currier, B., Yaszemski, M. J., Nassr, A., Huddleston, P., Bydon, M. & Freedman, B., Feb 1 2019, In : Spine Journal. 19, 2, p. 267-275 9 p.

Research output: Contribution to journalArticle

Surgical Wound Infection
Spine
Povidone-Iodine
Costs and Cost Analysis
Laminectomy

A Novel Anatomic Landmark to Assess Adequate Decompression in Anterior Cervical Spine Surgery: The Posterior Endplate Valley (PEV)

Aleem, I. S., Alder, J., Popper, J., Freedman, B., Nassr, A., Bydon, M., Yaszemski, M. J. & Currier, B. L., Jan 1 2019, (Accepted/In press) In : Clinical Spine Surgery.

Research output: Contribution to journalArticle

Anatomic Landmarks
Decompression
Spine
Phthiraptera
Retrospective Studies

Combinatorial tissue engineering partially restores function after spinal cord injury

Hakim, J. S., Rodysill, B. R., Chen, B. K., Schmeichel, A. M., Yaszemski, M. J., Windebank, A. J. & Madigan, N. N., Jan 1 2019, In : Journal of Tissue Engineering and Regenerative Medicine.

Research output: Contribution to journalArticle

Sirolimus
Tissue Engineering
Spinal Cord Injuries
Tissue engineering
Scaffolds

Effect of Biomaterial Electrical Charge on Bone Morphogenetic Protein-2-Induced In Vivo Bone Formation

Olthof, M. G. L., Kempen, D. H. R., Liu, X., Dadsetan, M., Tryfonidou, M. A., Yaszemski, M. J., Dhert, W. J. A. & Lu, L., Jul 1 2019, In : Tissue Engineering - Part A. 25, 13-14, p. 1037-1052 16 p.

Research output: Contribution to journalArticle

Bone Morphogenetic Protein 2
Biocompatible Materials
Osteogenesis
Biomaterials
Bone

Low dose radiotherapy is associated with local complications but not disease control in sacral chordoma

Other Members of the Sacral Tumor Society, Jan 1 2019, In : Journal of Surgical Oncology.

Research output: Contribution to journalArticle

Chordoma
Radiotherapy
Confidence Intervals
Radiation
Recurrence

Mechanical testing setups affect spine segment fracture outcomes

Rezaei, A., Giambini, H., Carlson, K. D., Xu, H., Uthamaraj, S., Dragomir Daescu, M. D., Yaszemski, M. J. & Lu, L., Dec 1 2019, In : Journal of the Mechanical Behavior of Biomedical Materials. 100, 103399.

Research output: Contribution to journalArticle

Mechanical testing
Testing
1 Citation (Scopus)

The Osteoinductive Effect of Controlled Bone Morphogenic Protein 2 Release Is Location Dependent

Olthof, M. G. L., Lu, L., Tryfonidou, M. A., Loozen, L. D., Pouran, B., Yaszemski, M. J., Meij, B. P., Dhert, W. J. A., Alblas, J. & Kempen, D. H. R., Feb 1 2019, In : Tissue Engineering - Part A. 25, 3-4, p. 193-202 10 p.

Research output: Contribution to journalArticle

Bone
Proteins
Bone and Bones
Osteogenesis
Porifera

Translating Orthopaedic Technologies Into Clinical Practice: Challenges and Solutions

Maher, S. A., Kyle, R., Morrey, B. F. & Yaszemski, M. J., Jan 1 2019, In : The Journal of the American Academy of Orthopaedic Surgeons. 27, 1, p. e9-e16

Research output: Contribution to journalArticle

Orthopedics
Intellectual Property
Technology
Cost of Illness
Critical Pathways
2018
3 Citations (Scopus)

A Combination of a Polycaprolactone Fumarate Scaffold with Polyethylene Terephthalate Sutures for Intra-Articular Ligament Regeneration

Parry, J. A., Wagner, E. R., Kok, P. L., Dadsetan, M., Yaszemski, M. J., van Wijnen, A. J. & Kakar, S., Feb 1 2018, In : Tissue Engineering - Part A. 24, 3-4, p. 245-253 9 p.

Research output: Contribution to journalArticle

Articular Ligaments
Polycaprolactone
Polyethylene Terephthalates
Ligaments
Scaffolds

Bone biology and engineering

Westendorf, J. J., Lu, L. & Yaszemski, M. J., Jan 1 2018, Orthopaedic Basic Science: Foundations of Clinical Practice, Fourth Edition. Wolters Kluwer Health, p. 281-293 13 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Bone and Bones
6 Citations (Scopus)

Bone morphogenetic protein-2 release profile modulates bone formation in phosphorylated hydrogel

Olthof, M. G. L., Kempen, D. H. R., Liu, X., Dadsetan, M., Tryfonidou, M. A., Yaszemski, M. J., Dhert, W. J. A. & Lu, L., Jan 1 2018, (Accepted/In press) In : Journal of Tissue Engineering and Regenerative Medicine.

Research output: Contribution to journalArticle

Bone Morphogenetic Protein 2
Hydrogel
Osteogenesis
Hydrogels
Bone
2 Citations (Scopus)

Decreased local and systemic levels of sFRP3 protein in osteosarcoma patients

Bravo, D., Salduz, A., Shogren, K. L., Okuno, M. N., Herrick, J. L., Okuno, S. H., Galindo, M., van Wijnen, A. J., Yaszemski, M. J. & Maran, A., Oct 20 2018, In : Gene. 674, p. 1-7 7 p.

Research output: Contribution to journalArticle

Osteosarcoma
Proteins
Neoplasms
Wnt Proteins
Tissue Array Analysis

Do Cervical Spine Surgery Patients Recall Their Preoperative Status? A Cohort Study of Recall Bias in Patient-reported Outcomes

Aleem, I. S., Currier, B. L., Yaszemski, M. J., Poppendeck, H., Huddleston, P., Eck, J., Rhee, J., Bydon, M., Freedman, B. & Nassr, A., Jan 1 2018, (Accepted/In press) In : Clinical Spine Surgery.

Research output: Contribution to journalArticle

Spine
Cohort Studies
Confidence Intervals
Arm
Neck Pain
1 Citation (Scopus)

Does recombinant human bone morphogenic protein 2 affect perioperative blood loss after lumbar and thoracic spinal fusion?

Wanderman, N., Carlson, B., Robinson, W., Bydon, M., Yaszemski, M. J., Huddleston, P. & Freedman, B., Jan 1 2018, In : Asian Spine Journal. 12, 5, p. 880-886 7 p.

Research output: Contribution to journalArticle

Spinal Fusion
Thorax
Bone and Bones
Proteins
Confidence Intervals
1 Citation (Scopus)

Does subcutaneous infiltration of liposomal bupivacaine following single-level transforaminal lumbar interbody fusion surgery improve immediate postoperative pain control?

Tomov, M., Tou, K., Winkel, R., Puffer, R., Bydon, M., Nassr, A., Huddleston, P., Yaszemski, M. J., Currier, B. & Freedman, B., Feb 1 2018, In : Asian Spine Journal. 12, 1, p. 85-93 9 p.

Research output: Contribution to journalArticle

Bupivacaine
Postoperative Pain
Narcotics
Patient-Controlled Analgesia
Pain
1 Citation (Scopus)

Efflux inhibition by IWR-1-endo confers sensitivity to doxorubicin effects in osteosarcoma cells

Gustafson, C. T., Mamo, T., Maran, A. & Yaszemski, M. J., Apr 1 2018, In : Biochemical Pharmacology. 150, p. 141-149 9 p.

Research output: Contribution to journalArticle

Osteosarcoma
Doxorubicin
Chemotherapy
Drug Therapy
Tankyrases

Establishing a current good manufacturing practice facility for biomaterials and biomolecules in an academic medical center

Greenberg-Worisek, A. J., Runge, B. K., Solyntjes, S. A., Helene-Kraft, J., Glass, S. L., Waletzki, B. E., Herrick, J. L., Miller, A. L., Yaszemski, M. J., Windebank, A. J. & Wang, H. D., Dec 1 2018, In : Tissue Engineering - Part B: Reviews. 24, 6, p. 493-498 6 p.

Research output: Contribution to journalReview article

Biocompatible Materials
Biomolecules
Biomaterials
Research Personnel
Equipment and Supplies
2 Citations (Scopus)

Extracellular matrix protein production in human adipose-derived mesenchymal stem cells on three-dimensional polycaprolactone (PCL) scaffolds responds to GDF5 or FGF2

Su, Y., Denbeigh, J. M., Camilleri, E. T., Riester, S. M., Parry, J. A., Wagner, E. R., Yaszemski, M. J., Dietz, A. B., Cool, S. M., van Wijnen, A. J. & Kakar, S., Mar 1 2018, In : Gene Reports. 10, p. 149-156 8 p.

Research output: Contribution to journalArticle

Growth Differentiation Factor 5
Extracellular Matrix Proteins
Fibroblast Growth Factor 2
Mesenchymal Stromal Cells
Tenascin
5 Citations (Scopus)

Inhibition of STAT3 blocks protein synthesis and tumor metastasis in osteosarcoma cells 06 Biological Sciences 0601 Biochemistry and Cell Biology

Zuo, D., Shogren, K. L., Zang, J., Jewison, D. E., Waletzki, B. E., Miller, A. L., Okuno, S. H., Cai, Z., Yaszemski, M. J. & Maran, A., Oct 4 2018, In : Journal of Experimental and Clinical Cancer Research. 37, 1, 244.

Research output: Contribution to journalArticle

Biological Science Disciplines
Osteosarcoma
Transducers
Biochemistry
Cell Biology
1 Citation (Scopus)

In Vitro and In Vivo Correlation of Bone Morphogenetic Protein-2 Release Profiles from Complex Delivery Vehicles

Olthof, M. G. L., Tryfonidou, M. A., Dadsetan, M., Dhert, W. J. A., Yaszemski, M. J., Kempen, D. H. R. & Lu, L., Jul 1 2018, In : Tissue Engineering - Part C: Methods. 24, 7, p. 379-390 12 p.

Research output: Contribution to journalArticle

Bone Morphogenetic Protein 2
Bone
Proteins
Bone Regeneration
Buffers
1 Citation (Scopus)

Joint contracture is reduced by intra-articular implantation of rosiglitazone-loaded hydrogels in a rabbit model of arthrofibrosis

Arsoy, D., Salib, C. G., Trousdale, W. H., Tibbo, M. E., Limberg, A. K., Viste, A., Lewallen, E. A., Reina, N., Yaszemski, M. J., Berry, D. J., van Wijnen, A. J., Morrey, M. E., Sanchez-Sotelo, J. & Abdel, M., Jan 1 2018, (Accepted/In press) In : Journal of Orthopaedic Research.

Research output: Contribution to journalArticle

rosiglitazone
Hydrogels
Contracture
Joints
Rabbits

Minimum 20-Year Health-Related Quality of Life and Surgical Rates After the Treatment of Adolescent Idiopathic Scoliosis

Larson, A. N., Baky, F., Ashraf, A., Baghdadi, Y. M., Treder, V., Polly, D. W. & Yaszemski, M. J., Jan 1 2018, (Accepted/In press) In : Spine Deformity.

Research output: Contribution to journalArticle

Scoliosis
Quality of Life
Therapeutics
Spine
Observation
5 Citations (Scopus)

Phosphate Functional Groups Improve Oligo[(Polyethylene Glycol) Fumarate] Osteoconduction and BMP-2 Osteoinductive Efficacy

Olthof, M. G. L., Tryfonidou, M. A., Liu, X., Pouran, B., Meij, B. P., Dhert, W. J. A., Yaszemski, M. J., Lu, L., Alblas, J. & Kempen, D. H. R., May 1 2018, In : Tissue Engineering - Part A. 24, 9-10, p. 819-829 11 p.

Research output: Contribution to journalArticle

Fumarates
Bone Regeneration
Functional groups
Polyethylene glycols
Bone

Raman spectroscopic and microscopic analysis for monitoring renal osteodystrophy signatures

Ciubuc, J. D., Manciu, M., Maran, A., Yaszemski, M. J., Sundin, E. M., Bennet, K. E. & Manciu, F. S., Apr 8 2018, In : Biosensors. 8, 2, 38.

Research output: Contribution to journalArticle

Chronic Kidney Disease-Mineral and Bone Disorder
Bone
Monitoring
Bone and Bones
Phenylalanine
2 Citations (Scopus)

RNA sequencing identifies gene regulatory networks controlling extracellular matrix synthesis in intervertebral disk tissues

Riester, S. M., Lin, Y., Wang, W., Cong, L., Mohamed Ali, A. M., Peck, S. H., Smith, L. J., Currier, B. L., Clark, M., Huddleston, P., Krauss, W., Yaszemski, M. J., Morrey, M. E., Abdel, M., Bydon, M., Qu, W., Larson, A. N., van Wijnen, A. J. & Nassr, A., Jan 1 2018, (Accepted/In press) In : Journal of Orthopaedic Research.

Research output: Contribution to journalArticle

RNA Sequence Analysis
Gene Regulatory Networks
Intervertebral Disc
Extracellular Matrix
Intercellular Signaling Peptides and Proteins

Skull base plasmacytoma: A unique case of POEMS syndrome with a plasmacytoma causing craniocervical instability

Gilder, H., Murphy, M. E., Alvi, M. A., Kerezoudis, P., Shepherd, D., Maloney, P. R., Yaszemski, M. J., Morris, J. M., Dispenzieri, A., Matsumoto, J. M. & Bydon, M., Jan 1 2018, In : Journal of Clinical Neuroscience. 47, p. 254-257 4 p.

Research output: Contribution to journalArticle

POEMS Syndrome
Plasmacytoma
Skull Base
Induction Chemotherapy
Plasma Cells
1 Citation (Scopus)

The American Orthopaedic Association’s Own the Bone® database: a national quality improvement project for the treatment of bone health in fragility fracture patients

Carlson, B. C., Robinson, W. A., Wanderman, N. R., Nassr, A. N., Huddleston, P. M., Yaszemski, M. J., Currier, B. L., Jeray, K. J., Kirk, K. L., Bunta, A. D., Murphy, S., Patel, B., Watkins, C. M., Sietsema, D. L., Edwards, B. J., Tosi, L. L., Anderson, P. A. & Freedman, B., Jun 1 2018, (Accepted/In press) In : Osteoporosis International. p. 1-9 9 p.

Research output: Contribution to journalArticle

Quality Improvement
Orthopedics
Databases
Bone and Bones
Registries

VEGF-mediated angiogenesis and vascularization of a fumarate-crosslinked polycaprolactone (PCLF) scaffold

Wagner, E. R., Parry, J., Dadsetan, M., Bravo, D., Riester, S. M., van Wijnen, A. J., Yaszemski, M. J. & Kakar, S., Mar 8 2018, (Accepted/In press) In : Connective Tissue Research. p. 1-8 8 p.

Research output: Contribution to journalArticle

Fumarates
Scaffolds
Vascular Endothelial Growth Factor A
Tissue
Tissue Scaffolds
2017
7 Citations (Scopus)

2-Methoxyestradiol-Mediated Induction of Frzb Contributes to Cell Death and Autophagy in MG63 Osteosarcoma Cells

Bravo, D., Shogren, K. L., Zuo, D., Wagner, E. R., Sarkar, G., Yaszemski, M. J. & Maran, A., Jun 1 2017, In : Journal of Cellular Biochemistry. 118, 6, p. 1497-1504 8 p.

Research output: Contribution to journalArticle

Autophagy
Cell death
Osteosarcoma
Cell Death
Tumors
2 Citations (Scopus)

A method to estimate cadaveric femur cortical strains during fracture testing using digital image correlation

Rossman, T., Uthamaraj, S., Rezaei, A., McEligot, S., Giambini, H., Jasiuk, I., Yaszemski, M. J., Lu, L. & Dragomir Daescu, M. D., Sep 14 2017, In : Journal of Visualized Experiments. 2017, 127, e54942.

Research output: Contribution to journalArticle

Fracture testing
Femur
Finite Element Analysis
Paint
Thigh
3 Citations (Scopus)

A New Vertebral Body Replacement Strategy Using Expandable Polymeric Cages

Liu, X., Paulsen, A., Giambini, H., Guo, J., Miller, A. L., Lin, P. C., Yaszemski, M. J. & Lu, L., Mar 1 2017, In : Tissue Engineering - Part A. 23, 5-6, p. 223-232 10 p.

Research output: Contribution to journalArticle

Hydrogel
Nerve Tissue
Fumarates
Biocompatible Materials
Operative Time
Skeletal Muscle
Staining and Labeling
Muscles
Photobleaching
Antigens
3 Citations (Scopus)

Anticancer efficiency of curcumin-loaded invertible polymer micellar nanoassemblies

Hevus, I., Voronov, A., Yaszemski, M. J., Maran, A., Kohut, A. & Voronov, S., Apr 14 2017, Nanostructures for Cancer Therapy. Elsevier Inc., p. 351-382 32 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Polymers
Cell membranes
Macromolecules
Conformations
Water
3 Citations (Scopus)

Are DXA/aBMD and QCT/FEA Stiffness and Strength Estimates Sensitive to Sex and Age?

Rezaei, A., Giambini, H., Rossman, T., Carlson, K. D., Yaszemski, M. J., Lu, L. & Dragomir Daescu, M. D., Sep 22 2017, (Accepted/In press) In : Annals of Biomedical Engineering. p. 1-10 10 p.

Research output: Contribution to journalArticle

Tomography
Bone
Minerals
Stiffness
Finite element method
1 Citation (Scopus)

Biopolymer-based intra-articular delivery of DKK1 into the contracted rabbit knee

Jo, S., Lewallen, E. A., Morrey, L. B., Riester, S. M., Trousdale, W. H., Salib, C. G., Reina, N., Yaszemski, M. J., Sanchez-Sotelo, J., Morrey, M. E., van Wijnen, A. J. & Abdel, M., Sep 1 2017, In : Gene Reports. 8, p. 69-74 6 p.

Research output: Contribution to journalArticle

Biopolymers
Knee
Joints
Rabbits
Contracture

Bone graft and bone graft alternatives in spine surgery: From bench to bedside

Parry, J. A. & Yaszemski, M. J., Jan 1 2017, Translating Biomaterials for Bone Graft: Bench-Top to Clinical Applications. CRC Press, p. 167-188 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Grafts
Surgery
Bone
Spine
Transplants
3 Citations (Scopus)

Chondrocyte Attachment, Proliferation, and Differentiation on Three-Dimensional Polycaprolactone Fumarate Scaffolds

Wagner, E. R., Parry, J., Dadsetan, M., Bravo, D., Riester, S. M., van Wijnen, A. J., Yaszemski, M. J. & Kakar, S., Jul 1 2017, In : Tissue Engineering - Part A. 23, 13-14, p. 622-629 8 p.

Research output: Contribution to journalArticle

Polycaprolactone
Chondrocytes
Scaffolds
Collagen
Blood Platelets
6 Citations (Scopus)

Effect of different sustained bone morphogenetic protein-2 release kinetics on bone formation in poly(propylene fumarate) scaffolds

Olthof, M. G. L., Kempen, D. H. R., Herrick, J. L., Yaszemski, M. J., Dhert, W. J. A. & Lu, L., 2017, (Accepted/In press) In : Journal of Biomedical Materials Research - Part B Applied Biomaterials.

Research output: Contribution to journalArticle

Bone Morphogenetic Protein 2
Scaffolds (biology)
Scaffolds
Polypropylenes
Bone
4 Citations (Scopus)

FH535 suppresses osteosarcoma growth in vitro and inhibits wnt signaling through tankyrases

Gustafson, C. T., Mamo, T., Shogren, K. L., Maran, A. & Yaszemski, M. J., May 23 2017, In : Frontiers in Pharmacology. 8, MAY, 285.

Research output: Contribution to journalArticle

Tankyrases
Osteosarcoma
Growth
Catenins
Enzymes
10 Citations (Scopus)
Hydrogel
Schwann Cells
Nerve Growth Factors
Spinal Cord Injuries
Hydrogels
8 Citations (Scopus)

Inhibiting DNA-PKCS radiosensitizes human osteosarcoma cells

Mamo, T., Mladek, A. C., Shogren, K. L., Gustafson, C., Gupta, S. K., Riester, S. M., Maran, A., Galindo, M., van Wijnen, A. J., Sarkaria, J. N. & Yaszemski, M. J., Apr 29 2017, In : Biochemical and Biophysical Research Communications. 486, 2, p. 307-313 7 p.

Research output: Contribution to journalArticle

lysyl-arginyl-alanyl-lysyl-alanyl-lysyl-threonyl-threonyl-lysyl-lysyl-arginine
Osteosarcoma
DNA
Cells
Cell Line
1 Citation (Scopus)

Interpreting the DXA analysis: When should you hold off on spinal fusion?

Wanderman, N., Freedman, B., Currier, B., Huddleston, P., Yaszemski, M. J. & Nassr, A., 2017, (Accepted/In press) In : Seminars in Spine Surgery.

Research output: Contribution to journalArticle

Spinal Fusion
Osteoporosis
X-Rays
Bone Density
Compression Fractures
2 Citations (Scopus)
Negotiating
Communication
Organizations
Medical Economics
Sexism
3 Citations (Scopus)

Method and Instrumented Fixture for Femoral Fracture Testing in a Sideways Fall-on-the-Hip Position

Dragomir Daescu, M. D., Rezaei, A., Rossman, T., Uthamaraj, S., Entwistle, R., McEligot, S., Lambert, V., Giambini, H., Jasiuk, I., Yaszemski, M. J. & Lu, L., Aug 17 2017, In : Journal of visualized experiments : JoVE. 126

Research output: Contribution to journalArticle

Fracture testing
Femoral Fractures
Femur
Hip
Bone
1 Citation (Scopus)

Molecular strategies for modulating Wnt signaling

Gustafson, C. T., Mamo, T., Maran, A. & Yaszemski, M. J., Jan 1 2017, In : Frontiers in bioscience (Landmark edition). 22, p. 137-156 20 p.

Research output: Contribution to journalReview article

Hedgehog Proteins
Wnt Proteins
Developmental Biology
Bone Morphogenetic Proteins
Regenerative Medicine
7 Citations (Scopus)

Novel porous poly(propylene fumarate-co-caprolactone) scaffolds fabricated by thermally induced phase separation

Guo, J., Liu, X., Lee Miller, A., Waletzki, B. E., Yaszemski, M. J. & Lu, L., Jan 1 2017, In : Journal of Biomedical Materials Research - Part A. 105, 1, p. 226-235 10 p.

Research output: Contribution to journalArticle

Scaffolds
Phase separation
Polypropylenes
Fumarates
Propylene
4 Citations (Scopus)
Pelvis
Spine
Transplants
Neoplasms
Disease-Free Survival
4 Citations (Scopus)

Proximal cadaveric femur preparation for fracture strength testing and quantitative CT-based finite element analysis

Dragomir Daescu, M. D., Rezaei, A., Uthamaraj, S., Rossman, T., Bronk, J. T., Bolander, M., Lambert, V., McEligot, S., Entwistle, R., Giambini, H., Jasiuk, I., Yaszemski, M. J. & Lu, L., Mar 11 2017, In : Journal of Visualized Experiments. 2017, 121, e54925.

Research output: Contribution to journalArticle

Finite Element Analysis
Femur
Fracture toughness
Bone
Finite element method

Sacral biomechanics and reconstruction

Sim, F. H., Houdek, M. T., Rose, P. S., Moran, S. L. & Yaszemski, M. J., May 30 2017, Tumors of the Sacrum: Diagnosis and Treatment of Benign and Malignant Tumors. Springer International Publishing, p. 321-332 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Biomechanical Phenomena
4 Citations (Scopus)

Three-Dimension-Printed Porous Poly(Propylene Fumarate) Scaffolds with Delayed rhBMP-2 Release for Anterior Cruciate Ligament Graft Fixation

Parry, J. A., Olthof, M. G. L., Shogren, K. L., Dadsetan, M., van Wijnen, A. J., Yaszemski, M. J. & Kakar, S., Apr 1 2017, In : Tissue Engineering - Part A. 23, 7-8, p. 359-365 7 p.

Research output: Contribution to journalArticle

Anterior Cruciate Ligament
Ligaments
Scaffolds (biology)
Grafts
Scaffolds