Projects per year
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Dive into the research topics where Mercedes Prudencio is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Discovery of novel TDP-43 splicing targets: the Achilles heel for FTD and towards sensitive biomarkers and therapeutic targets
Gitler, A. D., Fratta, P., Petrucelli, L., Prudencio, M., Prudencio, M. M. & Seeley, W. W.
9/15/21 → 8/31/24
Project: Research project
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Stathmin-2 and TDP-43 neurodegeneration in Alzheimer?s and multi-etiology dementias
Josephs, K. A. & Prudencio, M.
National Institute of Neurological Disorders and Stroke
4/1/21 → 3/31/24
Project: Research project
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Erratum: Neurofilament light chain and vaccination status associate with clinical outcomes in severe COVID-19 (iScience (2022) 25(11), (S2589004222015449), (10.1016/j.isci.2022.105272))
Erben, Y., Prudencio, M., Marquez, C. P., Jansen-West, K. R., Heckman, M. G., White, L. J., Dunmore, J. A., Cook, C. N., Lilley, M. T., Qosja, N., Song, Y., Al Shaikh, R. H., Daughrity, L. M., Bartfield, J. L., Day, G. S., Oskarsson, B., Nicholson, K. A., Wszolek, Z. K., Hoyne, J. B., Gendron, T. F., & 2 others , Apr 19 2024, In: iScience. 27, 4, 109501.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases
Calliari, A., Daughrity, L. M., Albagli, E. A., Castellanos Otero, P., Yue, M., Jansen-West, K., Islam, N. N., Caulfield, T., Rawlinson, B., DeTure, M., Cook, C., Graff-Radford, N. R., Day, G. S., Boeve, B. F., Knopman, D. S., Petersen, R. C., Josephs, K. A., Oskarsson, B., Gitler, A. D., Dickson, D. W., & 5 others , Dec 2024, In: Molecular neurodegeneration. 19, 1, 29.Research output: Contribution to journal › Letter › peer-review
Open Access -
Mis-spliced transcripts generate de novo proteins in TDP-43–related Als/FTD
Seddighi, S., Qi, Y. A., Brown, A. L., Wilkins, O. G., Bereda, C., Belair, C., Zhang, Y. J., Prudencio, M., Keuss, M. J., Khandeshi, A., Pickles, S., Kargbo-Hill, S. E., Hawrot, J., Ramos, D. M., Yuan, H., Roberts, J., Sacramento, E. K., Shah, S. I., Nalls, M. A., Colón-Mercado, J. M., & 31 others , 2024, In: Science translational medicine. 16, 734, eadg7162.Research output: Contribution to journal › Article › peer-review
Open Access -
TMEM106B core deposition associates with TDP-43 pathology and is increased in risk SNP carriers for frontotemporal dementia
Marks, J. D., Ayuso, V. E., Carlomagno, Y., Yue, M., Todd, T. W., Hao, Y., Li, Z., McEachin, Z. T., Shantaraman, A., Duong, D. M., Daughrity, L. M., Jansen-West, K., Shao, W., Calliari, A., Bejarano, J. G., DeTure, M., Rawlinson, B., Casey, M. C., Lilley, M. T., Donahue, M. H., & 16 others , Jan 17 2024, In: Science translational medicine. 16, 730, eadf9735.Research output: Contribution to journal › Article › peer-review
Open Access -
Author Correction: Toxic expanded GGGGCC repeat transcription is mediated by the PAF1 complex in C9orf72-associated FTD (Nature Neuroscience, (2019), 22, 6, (863-874), 10.1038/s41593-019-0396-1)
Goodman, L. D., Prudencio, M., Kramer, N. J., Martinez-Ramirez, L. F., Srinivasan, A. R., Lan, M., Parisi, M. J., Zhu, Y., Chew, J., Cook, C. N., Berson, A., Gitler, A. D., Petrucelli, L. & Bonini, N. M., Mar 2023, In: Nature Neuroscience. 26, 3, p. 528 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access