• 23550 Citations
  • 71 Scopus h-Index
1979 …2020

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Article

Increased renal cellular senescence in murine high-fat diet: effect of the senolytic drug quercetin

Kim, S. R., Jiang, K., Ogrodnik, M., Chen, X., Zhu, X. Y., Lohmeier, H., Ahmed, L., Tang, H., Tchkonia, T., Hickson, L. T. J., Kirkland, J. L. & Lerman, L. O., Nov 2019, In : Translational Research. 213, p. 112-123 12 p.

Research output: Contribution to journalArticle

18 Scopus citations

Increased oxidative stress in experimental renovascular hypertension

Lerman, L. O., Nath, K. A., Rodriguez-Porcel, M., Krier, J. D., Schwartz, R. S., Napoli, C. & Romero, J. C., 2001, In : Hypertension. 37, 2 II, p. 541-546 6 p.

Research output: Contribution to journalArticle

Open Access
231 Scopus citations

Increased hypoxia and reduced renal tubular response to furosemide detected by BOLD magnetic resonance imaging in swine renovascular hypertension

Gomez, S. I., Warner, L., Haas, J. A., Bolterman, R. J., Textor, S. C., Lerman, L. O. & Romero, J. C., Oct 2009, In : American Journal of Physiology - Renal Physiology. 297, 4, p. F981-F986

Research output: Contribution to journalArticle

41 Scopus citations

Increased glomerular filtration rate in early metabolic syndrome is associated with renal adiposity and microvascular proliferation

Li, Z., Woollard, J. R., Wang, S., Korsmo, M. J., Ebrahimi, B., Grande, J. P., Textor, S. C., Lerman, A. & Lerman, L. O., Nov 2011, In : American Journal of Physiology - Renal Physiology. 301, 5, p. F1078-F1087

Research output: Contribution to journalArticle

65 Scopus citations

Increased circulating inflammatory endothelial cells in blacks with essential hypertension

Eirin, A., Zhu, X. Y., Woollard, J. R., Herrmann, S. M., Gloviczki, M. L., Saad, A., Juncos, L. A., Calhoun, D. A., Rule, A. D., Lerman, A., Textor, S. C. & Lerman, L. O., Sep 2013, In : Hypertension. 62, 3, p. 585-591 7 p.

Research output: Contribution to journalArticle

22 Scopus citations

Increased cellular senescence in the murine and human stenotic kidney: Effect of mesenchymal stem cells

Kim, S. R., Zou, X., Tang, H., Puranik, A. S., Abumoawad, A. M., Zhu, X. Y., Hickson, L. T. J., Tchkonia, T., Textor, S. C., Kirkland, J. L. & Lerman, L. O., 2020, (Accepted/In press) In : Journal of Cellular Physiology.

Research output: Contribution to journalArticle

4 Scopus citations

Improved survival of mesenchymal stromal cell after hypoxia preconditioning: Role of oxidative stress

Peterson, K. M., Aly, A., Lerman, A., Lerman, L. O. & Rodriguez-Porcel, M., Jan 3 2011, In : Life Sciences. 88, 1-2, p. 65-73 9 p.

Research output: Contribution to journalArticle

76 Scopus citations

Improved renal outcomes after revascularization of the stenotic renal artery in pigs by prior treatment with low-energy extracorporeal shockwave therapy

Chen, X. J., Zhang, X., Jiang, K., Krier, J. D., Zhu, X., Lerman, A. & Lerman, L. O., Oct 1 2019, In : Journal of hypertension. 37, 10, p. 2074-2082 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Impaired renal vascular endothelial function in vitro in experimental hypercholesterolemia

Stulak, J. M., Lerman, A., Caccitolo, J. A., Wilson, S. H., Romero, J. C., Schaff, H. V., Porcel, M. R. & Lerman, L. O., Jan 8 2001, In : Atherosclerosis. 154, 1, p. 195-201 7 p.

Research output: Contribution to journalArticle

37 Scopus citations

Impaired myocardial perfusion reserve in experimental hypercholesterolemia is independent of myocardial neovascularization

Mannheim, D., Versari, D., Daghini, E., Gössl, M., Galili, O., Chade, A., Rajkumar, V. S., Ritman, E. L., Lerman, L. O. & Lerman, A., May 1 2007, In : American Journal of Physiology - Heart and Circulatory Physiology. 292, 5, p. H2449-H2458

Research output: Contribution to journalArticle

9 Scopus citations

Impaired myocardial autophagy linked to energy metabolism disorders

Li, Z. L. & Lerman, L. O., Jun 2012, In : Autophagy. 8, 6, p. 992-994 3 p.

Research output: Contribution to journalArticle

12 Scopus citations
Open Access
3 Scopus citations

Imaging: BOLD assessment - Effects of RAAS inhibition in CKD

Lerman, L. O., 2014, In : Nature Reviews Nephrology. 10, 5, p. 247-248 2 p.

Research output: Contribution to journalArticle

Imaging: BOLD assessment - Effects of RAAS inhibition in CKD

Lerman, L. O., May 2014, In : Nature Reviews Nephrology. 10, 5, p. 247-248 2 p.

Research output: Contribution to journalArticle

1 Scopus citations

Hypothyroidism Is Associated With Coronary Endothelial Dysfunction in Women

Sara, J. D., Zhang, M., Gharib, H., Lerman, L. O. & Lerman, A., Jul 29 2015, In : Journal of the American Heart Association. 4, 8, p. e002225

Research output: Contribution to journalArticle

21 Scopus citations

Hypertension exacerbates the effect of hypercholesterolemia on the myocardial microvasculature

Rodriguez-Porcel, M., Lerman, A., Herrmann, J., Schwartz, R. S., Sawamura, T., Condorelli, M., Napoli, C. & Lerman, L. O., May 1 2003, In : Cardiovascular research. 58, 1, p. 213-221 9 p.

Research output: Contribution to journalArticle

34 Scopus citations

Hypertension and hypercholesterolemia differentially affect the function and structure of pig carotid artery

Versari, D., Gossl, M., Mannheim, D., Daghini, E., Galili, O., Napoli, C., Lerman, L. O. & Lerman, A., Dec 2007, In : Hypertension. 50, 6, p. 1063-1068 6 p.

Research output: Contribution to journalArticle

11 Scopus citations
2 Scopus citations
77 Scopus citations
69 Scopus citations

Human renovascular disease: Estimating fractional tissue hypoxia to analyze blood oxygen level-dependent MR

Saad, A., Crane, J., Glockner, J. F., Herrmann, S. M. S., Friedman, H., Ebrahimi, B., Lerman, L. O. & Textor, S. C., Sep 2013, In : Radiology. 268, 3, p. 770-778 9 p.

Research output: Contribution to journalArticle

46 Scopus citations

Human Obesity Induces Dysfunction and Early Senescence in Adipose Tissue-Derived Mesenchymal Stromal/Stem Cells

Conley, S. M., Hickson, L. T. J., Kellogg, T. A., McKenzie, T., Heimbach, J. K., Taner, T., Tang, H., Jordan, K. L., Saadiq, I. M., Woollard, J. R., Isik, B., Afarideh, M., Tchkonia, T., Kirkland, J. L. & Lerman, L. O., Mar 26 2020, In : Frontiers in Cell and Developmental Biology. 8, 197.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Humanin prevents intra-renal microvascular remodeling and inflammation in hypercholesterolemic ApoE deficient mice

Zhang, X., Urbieta-Caceres, V. H., Eirin, A., Bell, C. C., Crane, J. A., Tang, H., Jordan, K. L., Oh, Y. K., Zhu, X. Y., Korsmo, M. J., Bachar, A. R., Cohen, P., Lerman, A. & Lerman, L. O., Sep 4 2012, In : Life Sciences. 91, 5-6, p. 199-206 8 p.

Research output: Contribution to journalArticle

38 Scopus citations

Humanin preserves endothelial function and prevents atherosclerotic plaque progression in hypercholesterolemic ApoE deficient mice

Oh, Y. K., Bachar, A. R., Zacharias, D. G., Kim, S. G., Wan, J., Cobb, L. J., Lerman, L. O., Cohen, P. & Lerman, A., Nov 2011, In : Atherosclerosis. 219, 1, p. 65-73 9 p.

Research output: Contribution to journalArticle

71 Scopus citations

Humanin is expressed in human vascular walls and has a cytoprotective effect against oxidized LDL-induced oxidative stress

Bachar, A. R., Scheffer, L., Schroeder, A. S., Nakamura, H. K., Cobb, L. J., Oh, Y. K., Lerman, L. O., Pagano, R. E., Cohen, P. & Lerman, A., Nov 1 2010, In : Cardiovascular research. 88, 2, p. 360-366 7 p.

Research output: Contribution to journalArticle

89 Scopus citations

Humanin, a cytoprotective peptide, is expressed in carotid artherosclerotic plaques in humans

Zacharias, D. G., Kim, S. G., Massat, A. E., Bachar, A. R., Oh, Y. K., Herrmann, J., Rodriguez-Porcel, M., Cohen, P., Lerman, L. O. & Lerman, A., Feb 6 2012, In : PloS one. 7, 2, e31065.

Research output: Contribution to journalArticle

33 Scopus citations

Human ghrelin: A gastric hormone with cardiovascular properties

Virdis, A., Lerman, L. O., Regoli, F., Ghiadoni, L., Lerman, A. & Taddei, S., Jan 1 2016, In : Current pharmaceutical design. 22, 1, p. 52-58 7 p.

Research output: Contribution to journalArticle

25 Scopus citations

High-sensitivity C-reactive protein is an independent marker of abnormal coronary vasoreactivity in patients with non-obstructive coronary artery disease

Sara, J. D. S., Prasad, M., Zhang, M., Lennon, R. J., Herrmann, J., Lerman, L. O. & Lerman, A., Aug 1 2017, In : American Heart Journal. 190, p. 1-11 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

High leukocyte count is associated with peripheral vascular dysfunction in individuals with low cardiovascular risk

Li, J., Flammer, A. J., Reriani, M. K., Matsuo, Y., Gulati, R., Friedman, P. A., Thomas, R. J., Sandhu, N. P., Lerman, L. O. & Lerman, A., 2013, In : Circulation Journal. 77, 3, p. 780-785 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Hemodynamic determinants of perivascular collateral development in swine renal artery stenosis

Krier, J. D., Crane, J. A., Eirin, A., Zhu, X. Y., Lerman, A. & Lerman, L. O., Feb 2013, In : American journal of hypertension. 26, 2, p. 209-217 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Heart rate-induced modifications of concentric left ventricular hypertrophy: Exploration of a novel therapeutic concept

Klein, F. J., Bell, S., Runte, K. E., Lobel, R., Ashikaga, T., Lerman, L. O., LeWinter, M. M. & Meyer, M., 2016, In : American Journal of Physiology - Heart and Circulatory Physiology. 311, 4, p. H1031-H1039

Research output: Contribution to journalArticle

4 Scopus citations
Open Access
2 Scopus citations

Glycoxidized low-density lipoprotein downregulates endothelial nitric oxide synthase in human coronary cells

Napoli, C., Lerman, L. O., De Nigris, F., Loscalzo, J. & Ignarro, L. J., Oct 16 2002, In : Journal of the American College of Cardiology. 40, 8, p. 1515-1522 8 p.

Research output: Contribution to journalArticle

35 Scopus citations

Glycoxidation of Low-Density Lipoprotein Increases TUNEL Positivity and CPP32 Activation in Human Coronary Cells

De Nigris, F., Tajana, G., Condorelli, M., D'Armiento, F. P., Sica, G., Lerman, L. O. & Napoli, C., Jan 1 2003, In : Annals of the New York Academy of Sciences. 1010, p. 710-715 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Glomerular volume and glomerulosclerosis at different depths within the human kidney

Denic, A., Ricaurte, L., Lopez, C. L., Narasimhan, R., Lerman, L. O., Lieske, J. C., Houston Thompson, R., Kremers, W. K. & Rule, A. D., Aug 2019, In : Journal of the American Society of Nephrology. 30, 8, p. 1471-1480 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Glomerular Hyperfiltration in Obese African American Hypertensive Patients Is Associated with Elevated Urinary Mitochondrial-DNA Copy Number

Eirin, A., Saad, A., Woollard, J. R., Juncos, L. A., Calhoun, D. A., Tang, H., Lerman, A., Textor, S. C. & Lerman, L. O., Nov 1 2017, In : American journal of hypertension. 30, 11, p. 1112-1119 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

Global epigenetic alterations of mesenchymal stem cells in obesity: the role of vitamin C reprogramming

Afarideh, M., Thaler, R., Khani, F., Tang, H., Jordan, K. L., Conley, S. M., Saadiq, I. M., Obeidat, Y., Pawar, A. S., Eirin, A., Zhu, X. Y., Lerman, A., van Wijnen, A. J. & Lerman, L. O., 2020, (Accepted/In press) In : Epigenetics.

Research output: Contribution to journalArticle

Genetic deficiency of Smad3 protects the kidneys from atrophy and interstitial fibrosis in 2K1C hypertension

Warner, G. M., Cheng, J., Knudsen, B. E., Gray, C. E., Deibel, A., Juskewitch, J. E., Lerman, L. O., Textor, S. C., Nath, K. A. & Grande, J. P., Jun 1 2012, In : American Journal of Physiology - Renal Physiology. 302, 11, p. F1455-F1464

Research output: Contribution to journalArticle

40 Scopus citations

Gained in translation: Protective paradigms for the poststenotic kidney

Lerman, L. O. & Textor, S. C., May 21 2015, In : Hypertension. 65, 5, p. 976-982 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Functional plasticity of adipose-derived stromal cells during development of obesity

Zhu, X. Y., Ma, S., Eirin, A., Woollard, J. R., Hickson, L. J., Sun, D., Lerman, A. & Lerman, L. O., 2016, In : Stem Cells Translational Medicine. 5, 7, p. 893-900 8 p.

Research output: Contribution to journalArticle

27 Scopus citations

Functional assessment of the kidney from magnetic resonance and computed tomography renography: Impulse retention approach to a multicompartment model

Zhang, J. L., Rusinek, H., Bokacheva, L., Lerman, L. O., Chen, Q., Prince, C., Oesingmann, N., Song, T. & Lee, V. S., Feb 2008, In : Magnetic Resonance in Medicine. 59, 2, p. 278-288 11 p.

Research output: Contribution to journalArticle

61 Scopus citations

Functional and structural remodeling of the myocardial microvasculature in early experimental hypertension

Rodriguez-Porcel, M., Zhu, X. Y., Chade, A. R., Amores-Arriaga, B., Caplice, N. M., Ritman, E. L., Lerman, A. & Lerman, L. O., Mar 2006, In : American Journal of Physiology - Heart and Circulatory Physiology. 290, 3, p. H978-H984

Research output: Contribution to journalArticle

39 Scopus citations

Fractional flow reserve with dobutamine challenge and coronary microvascular endothelial dysfunction in symptomatic myocardial bridging

Yoshino, S., Cassar, A., Matsuo, Y., Herrmann, J., Gulati, R., Prasad, A., Lennon, R. J., Lerman, L. O. & Lerman, A., 2014, In : Circulation Journal. 78, 3, p. 687-692 6 p.

Research output: Contribution to journalArticle

11 Scopus citations
9 Scopus citations

Extracellular vesicles released by adipose tissue-derived mesenchymal stromal/stem cells from obese pigs fail to repair the injured kidney

Eirin, A., Ferguson, C. M., Zhu, X. Y., Saadiq, I. M., Tang, H., Lerman, A. & Lerman, L. O., Aug 2020, In : Stem Cell Research. 47, 101877.

Research output: Contribution to journalArticle

Open Access

Extracellular matrix in cardiovascular pathophysiology: Chronic treatment with the mitochondrial peptide humanin prevents age-related myocardial fibrosis in mice

Qin, Q., Mehta, H., Yen, K., Navarrete, G., Brandhorst, S., Wan, J., Delrio, S., Zhang, X., Lerman, L. O., Cohen, P. & Lerman, A., Oct 2018, In : American Journal of Physiology - Heart and Circulatory Physiology. 315, 5, p. H1127-H1136

Research output: Contribution to journalArticle

16 Scopus citations

Expression of lipoprotein-associated phospholipase A2 in carotid artery plaques predicts long-term cardiac outcome

Herrmann, J., Mannheim, D., Wohlert, C., Versari, D., Meyer, F. B., McConnell, J. P., Gössl, M., Lerman, L. O. & Lerman, A., Dec 2009, In : European heart journal. 30, 23, p. 2930-2938 9 p.

Research output: Contribution to journalArticle

38 Scopus citations

Experimental renovascular disease induces endothelial cell mitochondrial damage and impairs endothelium-dependent relaxation of renal artery segments

Nargesi, A. A., Zhu, X. Y., Saadiq, I. M., Jordan, K. L., Lerman, A., Lerman, L. O. & Eirin, A., Aug 1 2020, In : American journal of hypertension. 33, 8, p. 765-774 10 p.

Research output: Contribution to journalArticle

Experimental Metabolic Syndrome Model Associated with Mechanical and Structural Degenerative Changes of the Aortic Valve

Go, J. L., Prem, K., Al-Hijji, M. A., Qin, Q., Noble, C., Young, M. D., Lerman, L. O. & Lerman, A., Dec 1 2018, In : Scientific reports. 8, 1, 17835.

Research output: Contribution to journalArticle

1 Scopus citations