Leonard Petrucelli, PhD

Professor

  • 13685 Citations
  • 63 h-Index
1992 …2021
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Amyotrophic Lateral Sclerosis Medicine & Life Sciences
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Frontotemporal Lobar Degeneration Medicine & Life Sciences
Alzheimer Disease Medicine & Life Sciences
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Projects 1999 2021

Tauopathies
Genes
Progressive Supranuclear Palsy
Research
Parkinsonian Disorders
Dipeptides
Proteins
Yeasts
Karyopherins
Neurons
Amyotrophic Lateral Sclerosis
Frontotemporal Lobar Degeneration
Methylation
RNA-Binding Proteins
Histones
Histone Deacetylases
Acetylation
Tauopathies
Antisense Oligonucleotides
Pathology

MAYO ALZHEIMERS DISEASE RESEARCH CENTER

Petrucelli, L., Tangalos, E. G., Jack, C. R. J., Dickson, D. W., Boeve, B. F., Younkin, S. G., Kantarci, K. M., Smith, G. E., Rademakers, R. V., Petersen, R. C., Pankratz, V. S., Yen, S. C., Tangalos, E. G., Jack, C. R. J., Dickson, D. W., Vemuri, P. D., Lucas, J. A., Knopman, D. S., Hutton, M. L., Bu, G. D., Edland, S. D., Hutton, M. L., Clifford, J., Kokman, E., Ertekin-Taner, N., Hutton, M. L. & Ertekin-Taner, N.

National Institutes of Health

5/1/994/30/19

Project: Research project

Alzheimer Disease
Research
Dementia
Lewy Body Disease
Brain

Research Output 1992 2019

  • 13685 Citations
  • 63 h-Index
  • 183 Article
  • 4 Chapter
  • 3 Review article
  • 1 Comment/debate

Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy

Chew, J., Cook, C., Gendron, T. D., Jansen-West, K., Del Rosso, G., Daughrity, L. M., Castanedes-Casey, M., Kurti, A., Stankowski, J. N., Disney, M. D., Rothstein, J. D., Dickson, D. W., Fryer, J. D., Zhang, Y. J. & Petrucelli, L., Feb 15 2019, In : Molecular neurodegeneration. 14, 1, 1 p.

Research output: Contribution to journalArticle

TDP-43 Proteinopathies
Dipeptides
RNA
Proteins
Antisense RNA

Enhanced phosphorylation of T153 in soluble tau is a defining biochemical feature of the A152T tau risk variant

Carlomagno, Y., Chung, D. E. C., Yue, M., Kurti, A., Avendano, N. M., Castanedes-Casey, M., Hinkle, K. M., Jansen-West, K., Daughrity, L. M., Tong, J., Phillips, V., Rademakers, R. V., Deture, M., Fryer, J. D., Dickson, D. W., Petrucelli, L. & Cook, C., Jan 23 2019, In : Acta neuropathologica communications. 7, 1, 1 p.

Research output: Contribution to journalArticle

Dependovirus
Phosphorylation
Tauopathies
Brain
Progressive Supranuclear Palsy

Erratum: Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease (Neuron (2018) 99(5) (925–940.e7), (S0896627318306378) (10.1016/j.neuron.2018.07.039))

Eftekharzadeh, B., Daigle, J. G., Kapinos, L. E., Coyne, A., Schiantarelli, J., Carlomagno, Y., Cook, C., Miller, S. J., Dujardin, S., Amaral, A. S., Grima, J. C., Bennett, R. E., Tepper, K., Deture, M., Vanderburg, C. R., Corjuc, B. T., DeVos, S. L., Gonzalez, J. A., Chew, J., Vidensky, S. & 10 othersGage, F. H., Mertens, J., Troncoso, J., Mandelkow, E., Salvatella, X., Lim, R. Y. H., Petrucelli, L., Wegmann, S., Rothstein, J. D. & Hyman, B. T., Jan 16 2019, In : Neuron. 101, 2, 1 p.

Research output: Contribution to journalComment/debate

tau Proteins
Cell Nucleus Active Transport
Names
Publications
Alzheimer Disease

Genetic Convergence Brings Clarity to the Enigmatic Red Line in ALS

Cook, C. & Petrucelli, L., Mar 20 2019, In : Neuron. 101, 6, p. 1057-1069 13 p.

Research output: Contribution to journalReview article

Amyotrophic Lateral Sclerosis
Neurodegenerative Diseases
Quality Control
Nervous System
Genes

Pathological, imaging and genetic characteristics support the existence of distinct TDP-43 types in non-FTLD brains

Josephs, K. A., Murray, M. E., Tosakulwong, N., Weigand, S. D., Serie, A. M., Perkerson, R. B., Matchett, B. J., Jack, C. R. J., Knopman, D. S., Petersen, R. C., Parisi, J. E., Petrucelli, L., Baker, M., Rademakers, R. V., Whitwell, J. L. & Dickson, D. W., Jan 1 2019, (Accepted/In press) In : Acta Neuropathologica.

Research output: Contribution to journalArticle

Amygdala
Frontotemporal Lobar Degeneration
Brain
Neuroimaging
Hippocampus