Projects per year
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Collaborations and top research areas from the last five years
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Investigating the role of TMEM106b genetics and pathology in Alzheimer’s disease, LATE and FTLD
Petrucelli, L. & Josephs, K. K. A.
National Institute of Neurological Disorders and Stroke
9/22/23 → 8/31/24
Project: Research project
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Novel genetic modifiers of C9orf72 and Tau toxicity
Fryer, J. D. & Petrucelli, L.
8/15/20 → 3/31/24
Project: Research project
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Mayo Alzheimer's Disease Research Center
Petersen, R. R. C., Boeve, B. F., Bu, G. D., Dickson, D. W., Kantarci, K. M., Knopman, D. S., Kremers, W. K., Petrucelli, L. & Lucas, J. A.
7/1/19 → 4/30/24
Project: Research project
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The mechanism by which loss of stathmin-2 induces neurodegeneration in ALS
Koike, Y. Y. & Petrucelli, L.
1/31/21 → 1/30/23
Project: Research project
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Clinicopathologic features of a novel star-shaped transactive response DNA-binding protein 43 (TDP-43) pathology in the oldest old
Carlos, A. F., Sekiya, H., Koga, S., Gatto, R. G., Casey, M. C., Pham, N. T. T., Sintini, I., Machulda, M. M., Jack, C. R., Lowe, V. J., Whitwell, J. L., Petrucelli, L., Reichard, R. R., Petersen, R. C., Dickson, D. W. & Josephs, K. A., Jan 1 2024, In: Journal of Neuropathology and Experimental Neurology. 83, 1, p. 36-52 17 p.Research output: Contribution to journal › Article › peer-review
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Artificial microRNA suppresses C9ORF72 variants and decreases toxic dipeptide repeat proteins in vivo
Cabrera, G. T., Meijboom, K. E., Abdallah, A., Tran, H., Foster, Z., Weiss, A., Wightman, N., Stock, R., Gendron, T., Gruntman, A., Giampetruzzi, A., Petrucelli, L., Brown, R. H. & Mueller, C., 2023, (Accepted/In press) In: Gene Therapy.Research output: Contribution to journal › Article › peer-review
Open Access -
Association of Physical Activity With Neurofilament Light Chain Trajectories in Autosomal Dominant Frontotemporal Lobar Degeneration Variant Carriers
for the ALLFTD Consortium, Jan 1 2023, In: JAMA neurology. 80, 1, p. 82-90 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Author Correction: Toxic expanded GGGGCC repeat transcription is mediated by the PAF1 complex in C9orf72-associated FTD (Nature Neuroscience, (2019), 22, 6, (863-874), 10.1038/s41593-019-0396-1)
Goodman, L. D., Prudencio, M., Kramer, N. J., Martinez-Ramirez, L. F., Srinivasan, A. R., Lan, M., Parisi, M. J., Zhu, Y., Chew, J., Cook, C. N., Berson, A., Gitler, A. D., Petrucelli, L. & Bonini, N. M., Mar 2023, In: Nature Neuroscience. 26, 3, p. 528 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
CRISPR interference to evaluate modifiers of C9ORF72-mediated toxicity in FTD
Pickles, S., Zanetti Alepuz, D., Koike, Y., Yue, M., Tong, J., Liu, P., Zhou, Y., Jansen-West, K., Daughrity, L. M., Song, Y., DeTure, M., Oskarsson, B., Graff-Radford, N. R., Boeve, B. F., Petersen, R. C., Josephs, K. A., Dickson, D. W., Ward, M. E., Dong, L., Prudencio, M., & 2 others , 2023, In: Frontiers in Cell and Developmental Biology. 11, 1251551.Research output: Contribution to journal › Article › peer-review
Open Access