Laura E. H. Raffals, MD, MS

  • 1368 Citations
  • 22 Scopus h-Index
20042020

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2020

Impact of Bariatric Surgery on the Long-term Disease Course of Inflammatory Bowel Disease

Braga Neto, M. B., Gregory, M. H., Ramos, G. P., Bazerbachi, F., Bruining, D. H., Abu Dayyeh, B. K., Kushnir, V. M., Raffals, L. E. H., Ciorba, M. A., Loftus, E. V. & Deepak, P., Jun 18 2020, In : Inflammatory bowel diseases. 26, 7, p. 1089-1097 9 p.

Research output: Contribution to journalArticle

Medical Education Interest, Exposure, and Career Planning in Subspecialty Trainees

Marshall, A. L., Thompson, C. A., Cullen, M. W., Raffals, L. E. & Oxentenko, A. S., 2020, (Accepted/In press) In : Medical Science Educator.

Research output: Contribution to journalArticle

Prospective multicenter study to evaluate capsule endoscopy competency using a validated assessment tool

Rajan, E., Martinez, M., Gorospe, E., Al Bawardy, B., Dobashi, A., Mara, K. C., Hansel, S. L., Bruining, D. H., Murray, J. A., Leggett, C. L., Nehra, V., Iyer, P. G., Pasha, S. F., Leighton, J. A., Shiff, A. D., Gurudu, S. R., Raffals, L. E., Lavey, C., Katzka, D. A. & Chen, C. H. H., May 2020, In : Gastrointestinal endoscopy. 91, 5, p. 1140-1145 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Unique Phenotypic Characteristics and Clinical Course in Patients with Ulcerative Colitis and Primary Sclerosing Cholangitis: A Multicenter US Experience

Wang, M. H., Mousa, O. Y., Friton, J. J., Raffals, L. E., Leighton, J. A., Pasha, S. F., Picco, M. F., Cushing, K. C., Monroe, K., Nix, B. D., Newberry, R. D. & Faubion, W. A., Apr 11 2020, In : Inflammatory bowel diseases. 26, 5, p. 774-779 6 p.

Research output: Contribution to journalArticle

2019

A Comprehensive Approach to Pouch Disorders

Quinn, K. P., Lightner, A., Faubion, W. A. & Raffals, L. E. H., Feb 21 2019, In : Inflammatory bowel diseases. 25, 3, p. 460-471 12 p.

Research output: Contribution to journalArticle

6 Scopus citations

An Increased Abundance of Clostridiaceae Characterizes Arthritis in Inflammatory Bowel Disease and Rheumatoid Arthritis: A Cross-sectional Study

Muñiz Pedrogo, D. A., Chen, J., Hillmann, B., Jeraldo, P., Al-Ghalith, G., Taneja, V., Davis, J. M., Knights, D., Nelson, H., Faubion, W. A., Raffals, L. & Kashyap, P. C., Apr 11 2019, In : Inflammatory bowel diseases. 25, 5, p. 902-913 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

Anti-TNF biologic therapy does not increase postoperative morbidity in pediatric Crohn's patients

Lightner, A., McKenna, N. P., Alsughayer, A., Loftus, Jr, E. V., Raffals, L. E. H., Faubion, W. A. & Moir, C., Jan 1 2019, In : Journal of pediatric surgery.

Research output: Contribution to journalArticle

3 Scopus citations

Appropriate Therapeutic Drug Monitoring of Biologic Agents for Patients With Inflammatory Bowel Diseases

Papamichael, K., Cheifetz, A. S., Melmed, G. Y., Irving, P. M., Vande Casteele, N., Kozuch, P. L., Raffals, L. E., Baidoo, L., Bressler, B., Devlin, S. M., Jones, J., Kaplan, G. G., Sparrow, M. P., Velayos, F. S., Ullman, T. & Siegel, C. A., Aug 2019, In : Clinical Gastroenterology and Hepatology. 17, 9, p. 1655-1668.e3

Research output: Contribution to journalArticle

Open Access
21 Scopus citations

Biologics and 30-Day Postoperative Complications after Abdominal Operations for Crohn's Disease: Are There Differences in the Safety Profiles?

Lightner, A., McKenna, N. P., Alsughayer, A., Harmsen, W. S., Taparra, K., Parker, M. E., Raffals, L. E. & Loftus, E. V., Nov 1 2019, In : Diseases of the colon and rectum. 62, 11, p. 1352-1362 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Efficacy of Vedolizumab for Refractory Pouchitis of the Ileo-anal Pouch: Results from a Multicenter US Cohort

Gregory, M., Weaver, K. N., Hoversten, P., Hicks, S. B., Patel, D., Ciorba, M. A., Gutierrez, A. M., Beniwal-Patel, P., Palam, S., Syal, G., Herfarth, H. H., Christophi, G., Raffals, L., Barnes, E. L. & Deepak, P., Sep 1 2019, In : Inflammatory bowel diseases. 25, 9, p. 1569-1576 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Novel Genetic Risk Variants Can Predict Anti-TNF Agent Response in Patients with Inflammatory Bowel Disease

Wang, M. H., Friton, J. J., Raffals, L. E., Leighton, J. A., Pasha, S. F., Picco, M. F., Cushing, K. C., Monroe, K., Nix, B. D., Newberry, R. D. & Faubion, W. A., Aug 14 2019, In : Journal of Crohn's and Colitis. 13, 8, p. 1036-1043 8 p., jjz017.

Research output: Contribution to journalArticle

1 Scopus citations

Submucosal Vascular Malformation as the Cause of Recurrent Obscure Bleed

Bies, M., Vijayvargiya, P. & Raffals, L., Jan 1 2019, In : Clinical Gastroenterology and Hepatology.

Research output: Contribution to journalArticle

Switching Between Biologics and Biosimilars in Inflammatory Bowel Disease

Raffals, L. E. H., Nguyen, G. C. & Rubin, D. T., Jan 1 2019, In : Clinical Gastroenterology and Hepatology.

Research output: Contribution to journalArticle

6 Scopus citations

Ustekinumab is effective for the treatment of crohn's disease of the pouch in a multicenter cohort

Weaver, K. N., Gregory, M., Syal, G., Hoversten, P., Hicks, S. B., Patel, D., Christophi, G., Beniwal-Patel, P., Isaacs, K. L., Raffals, L. E. H., Deepak, P., Herfarth, H. H. & Barnes, E. L., Mar 14 2019, In : Inflammatory bowel diseases. 25, 4, p. 767-774 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Vedolizumab Drug Level Correlation With Clinical Remission, Biomarker Normalization, and Mucosal Healing in Inflammatory Bowel Disease

Al-Bawardy, B., Ramos, G. P., Willrich, M. A. V., Jenkins, S. M., Park, S. H., Aniwan, S., Schoenoff, S. A., Bruining, D. H., Papadakis, K., Raffals, L. E. H., Tremaine, W. J. & Loftus, Jr, E. V., Feb 21 2019, In : Inflammatory bowel diseases. 25, 3, p. 580-586 7 p.

Research output: Contribution to journalArticle

14 Scopus citations

Vedolizumab in the Perioperative Management of Inflammatory Bowel Disease

Lightner, A., Edward V Loftus, V. L., McKenna, N. P. & Raffals, L. E., Jan 1 2019, In : Current drug targets. 20, 13, p. 1317-1322 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Volvulus of the ileal pouch-anal anastomosis: A meta-narrative systematic review of frequency, diagnosis, and treatment outcomes

Jawoosh, M., Haffar, S., Deepak, P., Meyers, A., Lightner, A. L., Larson, D. W., Raffals, L. H., Murad, M. H., Buttar, N. & Bazerbachi, F., Dec 1 2019, In : Gastroenterology Report. 7, 6, p. 403-410 8 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2018

AlphaE Integrin Expression Is Increased in the Ileum Relative to the Colon and Unaffected by Inflammation

Ichikawa, R., Lamb, C. A., Eastham-Anderson, J., Scherl, A., Raffals, L., Faubion, W. A., Bennett, M. R., Long, A. K., Mansfield, J. C., Kirby, J. A. & Keir, M. E., Nov 9 2018, In : Journal of Crohn's & colitis. 12, 10, p. 1191-1199 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

Antibiotic use and new-onset inflammatory bowel disease in Olmsted county, Minnesota: A population-based case-control study

Aniwan, S., Tremaine, W. J., Raffals, L. E. H., Kane, S. V. & Loftus, Jr, E. V., Jan 24 2018, In : Journal of Crohn's and Colitis. 12, 2, p. 137-144 8 p., jjx135.

Research output: Contribution to journalArticle

13 Scopus citations

Appropriateness of Combination Therapy for Patients With Inflammatory Bowel Diseases: One Size Still Does Not Fit All

Melmed, G. Y., Kaplan, G. G., Sparrow, M. P., Velayos, F. S., Baidoo, L., Bressler, B., Cheifetz, A. S., Devlin, S. M., Irving, P. M., Jones, J., Kozuch, P. L., Raffals, L. E. H. & Siegel, C. A., Jan 1 2018, (Accepted/In press) In : Clinical Gastroenterology and Hepatology.

Research output: Contribution to journalArticle

Clinical benefit of capsule endoscopy in Crohn's disease: Impact on patient management and prevalence of proximal small bowel involvement

Hansel, S. L., McCurdy, J. D., Barlow, J. M., Fidler, J. L., Fletcher, J. G., Becker, B., Prabhu, N. C., Faubion, W. A., Hanson, K. A., Kane, S. V., Kisiel, J. B., Loftus, E. V., Papadakis, K. A., Pardi, D. S., Raffals, L. E., Schoenoff, S., Tremaine, W. J. & Bruining, D. H., Jan 1 2018, In : Inflammatory Bowel Diseases. 24, 7, p. 1582-1588 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Clinical Response and Complications are not Associated with Drug Levels in Patients with Severe Ulcerative Colitis on IV Cyclosporine Induction Therapy

Patel, P., Yarur, A., Dalal, S., Sakuraba, A., Rubin, D. T., Hanauer, S. B., Hanan, I., Raffals, L. H., Cohen, R. D. & Pekow, J., May 18 2018, In : Inflammatory bowel diseases. 24, 6, p. 1291-1297 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

De-novo inflammatory bowel disease after bariatric surgery: A large case series

Neto, M. B. B., Gregory, M., Ramos, G. P., Loftus, E. V., Ciorba, M. A., Bruining, D. H., Bazerbachi, F., Abu Dayyeh, B. K., Kushnir, V. M., Shah, M., Collazo-Clavell, M. L., Raffals, L. E. & Deepak, P., Apr 2018, In : Journal of Crohn's and Colitis. 12, 4, p. 452-457 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

Depression is associated with more aggressive inflammatory bowel disease

Kochar, B., Barnes, E. L., Long, M. D., Cushing, K. C., Galanko, J., Martin, C. F., Raffals, L. E. H. & Sandler, R. S., Jan 1 2018, In : American Journal of Gastroenterology. 113, 1, p. 80-85 6 p.

Research output: Contribution to journalArticle

33 Scopus citations
21 Scopus citations

Hyperbaric oxygen therapy is well tolerated and effective for ulcerative colitis patients hospitalized for moderate–severe flares: a phase 2A pilot multi-center, randomized, double-blind, sham-controlled trial

Dulai, P. S., Buckey, J. C., Raffals, L. E. H., Swoger, J. M., Claus, P. L., O’Toole, K., Ptak, J. A., Gleeson, M. W., Widjaja, C. E., Chang, J. T., Adler, J. M., Patel, N., Skinner, L. A., Haren, S. P., Goldby-Reffner, K., Thompson, K. D. & Siegel, C. A., Feb 16 2018, (Accepted/In press) In : American Journal of Gastroenterology. p. 1-8 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Natural History of Established and de Novo Inflammatory Bowel Disease after Liver Transplantation for Primary Sclerosing Cholangitis

Loftus, E. V., Mouchli, M. A., Singh, S., Boardman, L., Bruining, D. H., Lightner, A. L., Rosen, C. B., Heimbach, J. K., Hasan, B., Poterucha, J. J., Watt, K. D., Kane, S. V. & Raffals, L. E., Apr 23 2018, In : Inflammatory bowel diseases. 24, 5, p. 1074-1081 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Non–Clostridium difficile Bacterial Infections Are Rare in Patients With Flares of Inflammatory Bowel Disease

Hanada, Y., Khanna, S., Loftus, Jr, E. V., Raffals, L. E. H. & Pardi, D. S., Apr 1 2018, In : Clinical Gastroenterology and Hepatology. 16, 4, p. 528-533 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Postoperative outcomes in Ustekinumab- treated patients undergoing abdominal operations for Crohn's disease

Lightner, A. L., McKenna, N. P., Tse, C. S., Hyman, N., Smith, R., Ovsepyan, G., Fleshner, P., Crowell, K., Koltun, W., Ferrante, M., D'Hoore, A., Lauwers, N., Verstockt, B., Spinelli, A., DiCandido, F., Raffals, L. E., Mathis, K. L. & Loftus, E. V., Apr 2018, In : Journal of Crohn's and Colitis. 12, 4, p. 402-407 6 p.

Research output: Contribution to journalArticle

29 Scopus citations

Postoperative outcomes in vedolizumab-treated Crohn's disease patients undergoing major abdominal operations

Lightner, A., McKenna, N. P., Tse, C. S., Raffals, L. E. H., Loftus, Jr, E. V. & Mathis, K. L., Mar 1 2018, In : Alimentary Pharmacology and Therapeutics. 47, 5, p. 573-580 8 p.

Research output: Contribution to journalArticle

31 Scopus citations

Response to Dai et al. and Gracie et al.

Kochar, B., Barnes, E. L., Long, M. D., Cushing, K. C., Galanko, J., Martin, C. F., Raffals, L. E. H. & Sandler, R. S., Apr 23 2018, (Accepted/In press) In : American Journal of Gastroenterology. 1 p.

Research output: Contribution to journalArticle

Response to Levenstein and Prantera

Kochar, B., Barnes, E. L., Long, M. D., Cushing, K. C., Galanko, J., Martin, C. F., Raffals, L. E. H. & Sandler, R. S., Jan 1 2018, (Accepted/In press) In : American Journal of Gastroenterology.

Research output: Contribution to journalArticle

Vedolizumab and early postoperative complications in nonintestinal surgery: a case-matched analysis

Kotze, P. G., Ma, C., Mckenna, N., Almutairdi, A., Kaplan, G. G., Raffals, L. E. H., Loftus, Jr, E. V., Panaccione, R. & Lightner, A., Jan 1 2018, In : Therapeutic Advances in Gastroenterology. 11

Research output: Contribution to journalArticle

3 Scopus citations
2017

Crohn's Disease of the Pouch: A True Diagnosis or an Oversubscribed Diagnosis of Exclusion?

Lightner, A., Fletcher, J. G., Pemberton, J. H., Mathis, K. L., Raffals, L. E. H. & Smyrk, T. C., Nov 1 2017, In : Diseases of the Colon and Rectum. 60, 11, p. 1201-1208 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

Early Transcriptomic Changes in the Ileal Pouch Provide Insight into the Molecular Pathogenesis of Pouchitis and Ulcerative Colitis

Huang, Y., Dalal, S., Antonopoulos, D., Hubert, N., Raffals, L. H., Dolan, K., Weber, C., Messer, J. S., Jabri, B., Bendelac, A., Eren, A. M., Rubin, D. T., Sogin, M. & Chang, E. B., Mar 1 2017, In : Inflammatory bowel diseases. 23, 3, p. 366-378 13 p.

Research output: Contribution to journalArticle

3 Scopus citations

Inflammatory Bowel Disease is Similar in Patients with Older Onset and Younger Onset

Kochar, B., Long, M. D., Galanko, J., Raffals, L. E. H., Ananthakrishnan, A. & Sandler, R. S., Jul 1 2017, In : Inflammatory Bowel Diseases. 23, 7, p. 1187-1194 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Isolated Acute Terminal Ileitis Without Preexisting Inflammatory Bowel Disease Rarely Progresses to Crohn’s Disease

Tse, C. S., Deepak, P., Smyrk, T. C. & Raffals, L. E. H., Oct 24 2017, (Accepted/In press) In : Digestive Diseases and Sciences. p. 1-6 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Nonrelaxing Pelvic Floor Dysfunction Is an Underestimated Complication of Ileal Pouch-Anal Anastomosis

Quinn, K. P., Tse, C. S., Lightner, A., Pendegraft, R. S., Enders, F. T. & Raffals, L. E. H., 2017, (Accepted/In press) In : Clinical Gastroenterology and Hepatology.

Research output: Contribution to journalArticle

16 Scopus citations

Postoperative Outcomes in Vedolizumab-Treated Patients Undergoing Abdominal Operations for Inflammatory Bowel Disease

Lightner, A., Raffals, L. E. H., Mathis, K. L., Cima, R. R., Tse, C. S., Pemberton, J. H., Dozois, E. & Loftus, Jr, E. V., Feb 1 2017, In : Journal of Crohn's & colitis. 11, 2, p. 185-190 6 p.

Research output: Contribution to journalArticle

65 Scopus citations

Preoperative Clostridium difficile Infection Does Not Affect Pouch Outcomes in Patients with Ulcerative Colitis Who Undergo Ileal Pouch-anal Anastomosis

Lightner, A. L., Tse, C. S., Quinn, K., Bergquist, J. R., Enders, F., Pendegraft, R., Khanna, S. & Raffals, L., Jul 1 2017, In : Inflammatory bowel diseases. 23, 7, p. 1195-1201 7 p.

Research output: Contribution to journalArticle

Results at Up to 30 Years after Ileal Pouch-Anal Anastomosis for Chronic Ulcerative Colitis

Lightner, A., Mathis, K. L., Dozois, E., Hahnsloser, D., Loftus, Jr, E. V., Raffals, L. E. H. & Pemberton, J. H., May 1 2017, In : Inflammatory Bowel Diseases. 23, 5, p. 781-790 10 p.

Research output: Contribution to journalArticle

31 Scopus citations

Surgical Outcomes in Vedolizumab-Treated Patients with Ulcerative Colitis

Lightner, A., McKenna, N. P., Moncrief, S., Pemberton, J. H., Raffals, L. E. H. & Mathis, K. L., Dec 1 2017, In : Inflammatory Bowel Diseases. 23, 12, p. 2197-2201 5 p.

Research output: Contribution to journalArticle

25 Scopus citations

The benefit of combination therapy depends on disease phenotype and duration in Crohn's disease

Ananthakrishnan, A. N., Sakuraba, A., Barnes, E. L., Pekow, J., Raffals, L. E. H., Long, M. D. & Sandler, R. S., Jul 1 2017, In : Alimentary Pharmacology and Therapeutics. 46, 2, p. 162-168 7 p.

Research output: Contribution to journalArticle

8 Scopus citations
17 Scopus citations
2016

A multidisciplinary approach to toxicity management of modern immune checkpoint inhibitors in cancer therapy

Kottschade, L., Brys, A., Peikert, T., Ryder, M., Raffals, L., Brewer, J., Mosca, P. & Markovic, S., Jan 1 2016, In : Melanoma research. 26, 5, p. 469-480 12 p.

Research output: Contribution to journalArticle

13 Scopus citations

Appropriateness of Testing for Anti–Tumor Necrosis Factor Agent and Antibody Concentrations, and Interpretation of Results

Melmed, G. Y., Irving, P. M., Jones, J., Kaplan, G. G., Kozuch, P. L., Velayos, F. S., Baidoo, L., Sparrow, M. P., Bressler, B., Cheifetz, A. S., Devlin, S. M., Raffals, L. E. H., Vande Casteele, N., Mould, D. R., Colombel, J. F., Dubinsky, M., Sandborn, W. J. & Siegel, C. A., 2016, In : Clinical Gastroenterology and Hepatology. 14, 9, p. 1302-1309 8 p.

Research output: Contribution to journalArticle

22 Scopus citations

Insights into the pathogenesis of ulcerative colitis from a murine model of stasis-induced dysbiosis, colonic metaplasia, and genetic susceptibility

Ward, M. A., Pierre, J. F., Leal, R. F., Huang, Y., Shogan, B., Dalal, S. R., Weber, C. R., Leone, V. A., Musch, M. W., An, G. C., Rao, M. C., Rubin, D. T., Raffals, L. E., Antonopoulos, D. A., Sogin, M. L., Hyman, N. H., Alverdy, J. C. & Chang, E. B., Jun 1 2016, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 310, 11, p. G973-G988

Research output: Contribution to journalArticle

16 Scopus citations

Patient-specific Bacteroides genome variants in pouchitis

Vineis, J. H., Ringus, D. L., Morrison, H. G., Delmont, T. O., Dalal, S., Raffals, L. H., Antonopoulos, D. A., Rubin, D. T., Eren, A. M., Chang, E. B. & Sogin, M. L., 2016, In : mBio. 7, 6, e01713-16.

Research output: Contribution to journalArticle

16 Scopus citations

Pouchitis Is a Common Complication in Patients With Familial Adenomatous Polyposis Following Ileal Pouch–Anal Anastomosis

Quinn, K. P., Lightner, A., Pendegraft, R. S., Enders, F. T., Boardman, L. A. & Raffals, L. E. H., 2016, In : Clinical Gastroenterology and Hepatology. 14, 9, p. 1296-1301 6 p.

Research output: Contribution to journalArticle

15 Scopus citations

Recommendations for quality colonoscopy reporting for patients with inflammatory bowel disease: Results from a RAND appropriateness panel

Devlin, S. M., Melmed, G. Y., Irving, P. M., Rubin, D. T., Kornbluth, A., Kozuch, P. L., Raffals, L. E. H., Velayos, F. S., Sparrow, M. P., Baidoo, L., Bressler, B., Cheifetz, A. S., Jones, J., Kaplan, G. G. & Siegel, C. A., Jun 1 2016, In : Inflammatory Bowel Diseases. 22, 6, p. 1418-1424 7 p.

Research output: Contribution to journalArticle

8 Scopus citations