Keith L Knutson, PhD

  • 11116 Citations
  • 49 Scopus h-Index
1993 …2020
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Research Output 1993 2019

  • 11116 Citations
  • 49 Scopus h-Index
  • 145 Article
  • 3 Chapter
  • 2 Review article
  • 1 Comment/debate
2019

Effects of age and immune landscape on outcome in HER2-positive breast cancer in the NCCTG N9831 (Alliance) and NSABP B-31 (NRG) trials

Chumsri, S., Serie, D. J., Li, Z., Pogue-Geile, K. L., Soyano-Muller, A. E., Mashadi-Hossein, A., Warren, S., Lou, Y., Colon-Otero, G., Knutson, K. L., Perez, E. A., Moreno Aspitia, A. & Thompson, E. A., Jan 1 2019, In : Clinical Cancer Research. 25, 14, p. 4422-4430 9 p.

Research output: Contribution to journalArticle

Breast Neoplasms
adjuvant P40
B 31
Trastuzumab

Hypereosinophilia in a patient with metastatic non-small-cell lung cancer treated with antiprogrammed cell death 1 (anti-PD-1) therapy

Lou, Y., Marin-Acevedo, J. A., Vishnu, P., Manochakian, R., Dholaria, B., Soyano, A., Luo, Y., Zhang, Y. & Knutson, K. L., May 1 2019, In : Immunotherapy. 11, 7, p. 577-584 8 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Eosinophilia
Cell Death
Therapeutics
Eosinophils
1 Citation (Scopus)

The evolving clinical landscape for dendritic cell vaccines and cancer immunotherapy

Cannon, M. J., Block, M. S., Morehead, L. C. & Knutson, K. L., Feb 1 2019, In : Immunotherapy. 11, 2, p. 75-79 5 p.

Research output: Contribution to journalComment/debate

Cancer Vaccines
Glioblastoma
Pancreatic Neoplasms
Acute Myeloid Leukemia
Ovarian Neoplasms
2018
32 Citations (Scopus)

Cancer immunotherapy beyond immune checkpoint inhibitors

Marin-Acevedo, J. A., Soyano, A. E., Dholaria, B., Knutson, K. L. & Lou, Y., Jan 12 2018, In : Journal of Hematology and Oncology. 11, 1, 8.

Research output: Contribution to journalReview article

Immunotherapy
Immune System
Neoplasms
CD274 Antigen
Programmed Cell Death 1 Receptor
6 Citations (Scopus)

Folate receptor alpha peptide vaccine generates immunity in breast and ovarian cancer patients

Kalli, K. R., Block, M. S., Kasi, P. M., Erskine, C. L., Hobday, T. J., Dietz, A. B., Padley, D., Gustafson, M., Shreeder, B., Puglisi-Knutson, D., Visscher, D. W., Mangskau, T. K., Wilson, G. & Knutson, K. L., Jul 1 2018, In : Clinical Cancer Research. 24, 13, p. 3014-3025 12 p.

Research output: Contribution to journalArticle

Folate Receptor 1
Subunit Vaccines
Ovarian Neoplasms
Immunity
Breast Neoplasms
1 Citation (Scopus)

Generation of HER2-specific antibody immunity during trastuzumab adjuvant therapy associates with reduced relapse in resected HER2 breast cancer

Norton, N., Fox, N., McCarl, C. A., Tenner, K. S., Ballman, K., Erskine, C. L., Necela, B. M., Northfelt, D. W., Tan, W., Calfa, C., Pegram, M., Colon-Otero, G., Perez, E. A., Clynes, R. & Knutson, K. L., Jun 14 2018, In : Breast Cancer Research. 20, 1, 52.

Research output: Contribution to journalArticle

Immunity
Breast Neoplasms
Recurrence
Antibodies
Disease-Free Survival
9 Citations (Scopus)

Macrophagic "crown-like structures" are associated with an increased risk of breast cancer in Benign Breast Disease

Carter, J., Hoskin, T. L., Pena, M. A., Brahmbhatt, R., Winham, S. J., Frost, M. H., Stallings-Mann, M., Radisky, D. C., Knutson, K. L., Visscher, D. W. & Degnim, A. C., Feb 1 2018, In : Cancer Prevention Research. 11, 2, p. 113-119 7 p.

Research output: Contribution to journalArticle

Breast Diseases
Crowns
Breast Neoplasms
Breast
Tissue Banks
89 Citations (Scopus)

Next generation of immune checkpoint therapy in cancer: New developments and challenges

Marin-Acevedo, J. A., Dholaria, B., Soyano, A. E., Knutson, K. L., Chumsri, S. & Lou, Y., Mar 15 2018, In : Journal of Hematology and Oncology. 11, 1, 39.

Research output: Contribution to journalReview article

CD274 Antigen
Neoplasms
Cytotoxic T-Lymphocytes
Programmed Cell Death 1 Receptor
Therapeutics
8 Citations (Scopus)

Peripheral blood biomarkers correlate with outcomes in advanced non-small cell lung Cancer patients treated with anti-PD-1 antibodies

Soyano, A. E., Dholaria, B., Marin-Acevedo, J. A., Diehl, N., Hodge, D., Luo, Y., Manochakian, R., Chumsri, S., Adjei, A., Knutson, K. L. & Lou, Y., Nov 23 2018, In : Journal for ImmunoTherapy of Cancer. 6, 1, 129.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Cell Death
Lymphocyte Count
Biomarkers
Neutrophils
2017
10 Citations (Scopus)

Alterations in the immune cell composition in premalignant breast tissue that precede breast cancer development

Degnim, A. C., Hoskin, T. L., Arshad, M., Frost, M. H., Winham, S. J., Brahmbhatt, R. A., Pena, A., Carter, J., Stallings-Mann, M. L., Murphy, L. M., Miller, E. E., Denison, L. A., Vachon, C. M., Knutson, K. L., Radisky, D. C. & Visscher, D. W., Jul 15 2017, In : Clinical Cancer Research. 23, 14, p. 3945-3952 8 p.

Research output: Contribution to journalArticle

Breast Diseases
Breast
Breast Neoplasms
B-Lymphocytes
Tissue Banks
1 Citation (Scopus)

CD56+ immune cell infiltration and MICA are decreased in breast lobules with fibrocystic changes

Kerekes, D., Visscher, D. W., Hoskin, T. L., Radisky, D. C., Brahmbhatt, R. D., Pena, A., Frost, M. H., Arshad, M., Stallings-Mann, M., Winham, S. J., Murphy, L., Denison, L., Carter, J., Knutson, K. L. & Degnim, A. C., Nov 1 2017, (Accepted/In press) In : Breast Cancer Research and Treatment. p. 1-10 10 p.

Research output: Contribution to journalArticle

Natural Killer Cells
Breast
Breast Diseases
Ligands
Neoplasms
2 Citations (Scopus)
Knee Replacement Arthroplasties
Neuropeptides
Cytokines
Pain
Substance P

Downregulation of TAP1 and TAP2 in early stage breast cancer

Henle, A. M., Nassar, A., Puglisi-Knutson, D., Youssef, B. & Knutson, K. L., Nov 1 2017, In : PLoS One. 12, 11, e0187323.

Research output: Contribution to journalArticle

breast neoplasms
Tumors
Down-Regulation
Breast Neoplasms
neoplasms
18 Citations (Scopus)

IL10 release upon PD-1 blockade sustains immunosuppression in ovarian cancer

Lamichhane, P., Karyampudi, L., Shreeder, B., Krempski, J., Bahr, D., Daum, J., Kalli, K. R., Goode, E. L., Block, M. S., Cannon, M. J. & Knutson, K. L., Dec 1 2017, In : Cancer Research. 77, 23, p. 6667-6678 12 p.

Research output: Contribution to journalArticle

Interleukin-10
Ovarian Neoplasms
Immunosuppression
Cell Death
Dendritic Cells
4 Citations (Scopus)
Lymphoma
Central Nervous System
Monoclonal Antibodies
Therapeutics
32 Citations (Scopus)

Multivalent bi-specific nanobioconjugate engager for targeted cancer immunotherapy

Yuan, H., Jiang, W., von Roemeling, C. A., Qie, Y., Liu, X., Chen, Y., Wang, Y., Wharen, R. E., Yun, K., Bu, G. D., Knutson, K. L. & Kim, Y. S. B., May 1 2017, (Accepted/In press) In : Nature Nanotechnology.

Research output: Contribution to journalArticle

Tumors
cancer
Cells
tumors
Calreticulin
1 Citation (Scopus)

The Association of Peripheral Blood Regulatory T-Cell Concentrations with Epithelial Ovarian Cancer: A Brief Report

Cannioto, R. A., Sucheston-Campbell, L. E., Hampras, S., Goode, E. L., Knutson, K. L., Ness, R., Modugno, F., Wallace, P. K., Szender, J. B., Mayor, P., Hong, C. C., Joseph, J. M., Friel, G., Davis, W., Nesline, M., Eng, K. H., Edwards, R. P., Kruszka, B., Schmitt, K., Odunsi, K. & 1 others, Moysich, K. B., Jan 1 2017, In : International Journal of Gynecological Cancer. 27, 1, p. 11-16 6 p.

Research output: Contribution to journalArticle

Regulatory T-Lymphocytes
Neoplasms
Odds Ratio
Confidence Intervals
Ovarian epithelial cancer

Viral-like proteins

Karyampudi, L. & Knutson, K. L., Jan 1 2017, Cancer Therapeutic Targets. Springer New York, Vol. 1-2. p. 545-559 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Viral Proteins
Neoplasms
Proteins
Immunotherapy
Carcinogenesis
2016
2 Citations (Scopus)

Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with risk of clear cell ovarian cancer

On behalf of the Australian Ovarian Cancer Study Group, 2016, In : Oncotarget. 7, 43, p. 69097-69110 14 p.

Research output: Contribution to journalArticle

Immunosuppressive Agents
Ovarian Neoplasms
Regulatory T-Lymphocytes
Genes
Single Nucleotide Polymorphism
22 Citations (Scopus)

Improved survival of HER2+ breast cancer patients treated with trastuzumab and chemotherapy is associated with host antibody immunity against the HER2 intracellular domain

Knutson, K. L., Clynes, R., Shreeder, B., Yeramian, P., Kemp, K. P., Ballman, K., Tenner, K. S., Erskine, C. L., Norton, N., Northfelt, D. W., Tan, W., Calfa, C., Pegram, M., Mittendorf, E. A. & Perez, E. A., Jul 1 2016, In : Cancer Research. 76, 13, p. 3702-3710 9 p.

Research output: Contribution to journalArticle

Immunity
Breast Neoplasms
Drug Therapy
Survival
Antibodies
18 Citations (Scopus)

PD-1 blunts the function of ovarian tumor-infiltrating dendritic cells by inactivating NF-κB

Karyampudi, L., Lamichhane, P., Krempski, J., Kalli, K. R., Behrens, M. D., Vargas, D. M., Hartmann, L. C., Janco, J. M. T., Dong, H. M., Hedin, K. E., Dietz, A. B., Goode, E. L. & Knutson, K. L., Jan 15 2016, In : Cancer Research. 76, 2, p. 239-250 12 p.

Research output: Contribution to journalArticle

Dendritic Cells
Neoplasms
Lymphocytes
Antigen Presentation
Myeloid Cells
1 Citation (Scopus)

Retraction Note: Retraction note to: Targeted immune therapy of ovarian cancer

Knutson, K. L., Karyampudi, L., Lamichhane, P. & Preston, C., May 30 2016, (Accepted/In press) In : Cancer and Metastasis Reviews. p. 1 1 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Melissa
Neoplasm Metastasis
Immunotherapy
Immune System
50 Citations (Scopus)

The microbiome of aseptically collected human breast tissue in benign and malignant disease

Hieken, T. J., Chen, J., Hoskin, T. L., Walther-Antonio, M., Johnson, S., Ramaker, S., Xiao, J., Radisky, D. C., Knutson, K. L., Kalari, K. R., Yao, J. Z., Baddour, L. M., Chia, N. D. & Degnim, A. C., Aug 3 2016, In : Scientific Reports. 6, 30751.

Research output: Contribution to journalArticle

Microbiota
Breast
Skin
Neoplasms
Gluconacetobacter
2015
2 Citations (Scopus)

Cancer vaccines in the new era of cancer immunotherapy

Knutson, K. L. & Mittendorf, E. A., Dec 16 2015, In : Vaccine. 33, 51, p. 7376 1 p.

Research output: Contribution to journalArticle

Cancer Vaccines
immunotherapy
Drug Discovery
Immunotherapy
vaccines
13 Citations (Scopus)

Combinatorial immunoprofiling in latent tuberculosis infection: Toward better risk stratification

Escalante, P., Peikert, T. D., Van Keulen, V. P., Erskine, C. L., Bornhorst, C. L., Andrist, B. R., McCoy, K., Pease, L. R., Abraham, R. S., Knutson, K. L., Kita, H., Schrum, A. G. & Limper, A. H., Sep 1 2015, In : American Journal of Respiratory and Critical Care Medicine. 192, 5, p. 605-617 13 p.

Research output: Contribution to journalArticle

Latent Tuberculosis
Immunoassay
Tuberculosis
Phenotype
T-Lymphocytes
68 Citations (Scopus)

Oncolytic measles virus expressing the sodium iodide symporter to treat drug-resistant ovarian cancer

Galanis, E., Atherton, P. J., Maurer, M. J., Knutson, K. L., Dowdy, S. C., Cliby, W. A., Haluska, P., Long, H. J., Oberg, A. L., Aderca, I., Block, M. S., Bakkum-Gamez, J. N., Federspiel, M. J., Russell, S. J., Kalli, K. R., Keeney, G., Peng, K-W. & Hartmann, L. C., Jan 1 2015, In : Cancer Research. 75, 1, p. 22-30 9 p.

Research output: Contribution to journalArticle

Oncolytic Viruses
Measles virus
Ovarian Neoplasms
Pharmaceutical Preparations
Neoplasms
14 Citations (Scopus)

Plasma immune analytes in patients with epithelial ovarian cancer

Block, M. S., Maurer, M. J., Goergen, K., Kalli, K. R., Erskine, C. L., Behrens, M. D., Oberg, A. L. & Knutson, K. L., May 1 2015, In : Cytokine. 73, 1, p. 108-113 6 p.

Research output: Contribution to journalArticle

Plasmas
Interleukin-6
Intercellular Signaling Peptides and Proteins
Interleukin-8
Antigens
21 Citations (Scopus)

Regulatory T cells, inherited variation, and clinical outcome in epithelial ovarian cancer

Knutson, K. L., Maurer, M. J., Preston, C. C., Moysich, K. B., Goergen, K., Hawthorne, K. M., Cunningham, J. M., Odunsi, K., Hartmann, L. C., Kalli, K. R., Oberg, A. L. & Goode, E. L., Aug 23 2015, (Accepted/In press) In : Cancer Immunology, Immunotherapy.

Research output: Contribution to journalArticle

Regulatory T-Lymphocytes
T-Lymphocytes
Ovarian Neoplasms
Interleukin-10
Survival
24 Citations (Scopus)

Targeted immune therapy of ovarian cancer

Knutson, K. L., Karyampudi, L., Lamichhane, P. & Preston, C., 2015, In : Cancer and Metastasis Reviews. 34, 1, p. 53-74 22 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Immune System
Immunity
Tumor Microenvironment
Therapeutics
116 Citations (Scopus)

Tumor-infiltrating dendritic cells in cancer pathogenesis

Janco, J. M. T., Lamichhane, P., Karyampudi, L. & Knutson, K. L., Apr 1 2015, In : Journal of Immunology. 194, 7, p. 2985-2991 7 p.

Research output: Contribution to journalArticle

Dendritic Cells
Neoplasms
Tumor Microenvironment
Immune System Diseases
Immunosuppressive Agents
2014
70 Citations (Scopus)

Accumulation of memory precursor cd8 t cells in regressing tumors following combination therapy with vaccine and anti-pd-1 antibody

Karyampudi, L., Lamichhane, P., Scheid, A. D., Kalli, K. R., Shreeder, B., Krempski, J. W., Behrens, M. D. & Knutson, K. L., Jun 1 2014, In : Cancer Research. 74, 11, p. 2974-2985 12 p.

Research output: Contribution to journalArticle

Active Immunotherapy
Tumor Microenvironment
Breast Neoplasms
T-Lymphocytes
Vaccines
23 Citations (Scopus)

Association studies of Fcγ receptor polymorphisms with outcome in HER2+ breast cancer patients treated with trastuzumab in NCCTG (Alliance) Trial N9831

Norton, N., Olson, R. M., Pegram, M., Tenner, K., Ballman, K. V., Clynes, R., Knutson, K. L. & Perez, E. A., Oct 1 2014, In : Cancer immunology research. 2, 10, p. 962-969 8 p.

Research output: Contribution to journalArticle

Fc Receptors
Breast Neoplasms
Genotype
Disease-Free Survival
Drug Therapy
113 Citations (Scopus)

AXL induces epithelial-to-mesenchymal transition and regulates the function of breast cancer stem cells

Asiedu, M. K., Beauchamp-Perez, F. D., Ingle, J. N., Behrens, M. D., Radisky, D. C. & Knutson, K. L., 2014, In : Oncogene. 33, 10, p. 1316-1324 9 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Neoplastic Stem Cells
Breast Neoplasms
Breast
Epithelial Cells
28 Citations (Scopus)

Immune cell quantitation in normal breast tissue lobules with and without lobulitis

Degnim, A. C., Brahmbhatt, R. D., Radisky, D. C., Hoskin, T. L., Stallings-Mann, M., Laudenschlager, M., Mansfield, A., Frost, M. H., Murphy, L., Knutson, K. L. & Visscher, D. W., 2014, In : Breast Cancer Research and Treatment. 144, 3, p. 539-549 11 p.

Research output: Contribution to journalArticle

Breast
Dendritic Cells
Monocytes
Macrophages
T-Lymphocytes
14 Citations (Scopus)

Large-scale evaluation of common variation in regulatory T cell-related genes and ovarian cancer outcome

AOCS Group, Apr 1 2014, In : Cancer immunology research. 2, 4, p. 332-340 9 p.

Research output: Contribution to journalArticle

Regulatory T-Lymphocytes
Ovarian Neoplasms
Single Nucleotide Polymorphism
Confidence Intervals
Survival
27 Citations (Scopus)

Risk of ovarian cancer and the NF-kB pathway: Genetic association with IL1A and TNFSF10

Charbonneau, B., Block, M. S., Bamlet, W. R., Vierkant, R. A., Kalli, K. R., Fogarty, Z., Rider, D. N., Sellers, T. A., Tworoger, S. S., Poole, E., Risch, H. A., Salvesen, H. B., Kiemeney, L. A., Baglietto, L., Giles, G. G., Severi, G., Trabert, B., Wentzensen, N., Chenevix-Trench, G., Whittemore, A. S. & 109 others, Sieh, W., Chang-Claude, J., Bandera, E. V., Orlow, I., Terry, K., Goodman, M. T., Thompson, P. J., Cook, L. S., Rossing, M. A., Ness, R. B., Narod, S. A., Kupryjanczyk, J., Lu, K., Butzow, R., Dork, T., Pejovic, T., Campbell, I., Le, N. D., Bunker, C. H., Bogdanova, N., Runnebaum, I. B., Eccles, D., Paul, J., Wu, A. H., Gayther, S. A., Hogdall, E., Heitz, F., Kaye, S. B., Karlan, B. Y., Anton-Culver, H., Gronwald, J., Hogdall, C. K., Lambrechts, D., Fasching, P. A., Menon, U., Schildkraut, J., Pearce, C. L., Levine, D. A., Kjaer, S. K., Cramer, D., Flanagan, J. M., Phelan, C. M., Brown, R., Massuger, L. F. A. G., Song, H., Doherty, J. A., Krakstad, C., Liang, D., Odunsi, K., Berchuck, A., Jensen, A., Lubinski, J., Nevanlinna, H., Bean, Y. T., Lurie, G., Ziogas, A., Walsh, C., Despierre, E., Brinton, L., Hein, A., Rudolph, A., Dansonka-Mieszkowska, A., Olson, S. H., Harter, P., Tyrer, J., Vitonis, A. F., Brooks-Wilson, A., Aben, K. K., Pike, M. C., Ramus, S. J., Wik, E., Cybulski, C., Lin, J., Sucheston, L., Edwards, R., McGuire, V., Lester, J., Du Bois, A., Lundvall, L., Wang-Gohrke, S., Szafron, L. M., Lambrechts, S., Yang, H., Beckmann, M. W., Pelttari, L. M., Van Altena, A. M., Van Den Berg, D., Halle, M. K., Gentry-Maharaj, A., Schwaab, I., Chandran, U., Menkiszak, J., Ekici, A. B., Wilkens, L. R., Leminen, A., Modugno, F., Friel, G., Rothstein, J. H., Vergote, I., Garcia-Closas, M., Hildebrandt, M. A. T., Sobiczewski, P., Kelemen, L. E., Pharoah, P. D. P., Moysich, K., Knutson, K. L., Cunningham, J. M., Fridley, B. L. & Goode, E. L., Feb 1 2014, In : Cancer Research. 74, 3, p. 852-861 10 p.

Research output: Contribution to journalArticle

NF-kappa B
Interleukins
Ovarian Neoplasms
Single Nucleotide Polymorphism
Confidence Intervals
13 Citations (Scopus)

Tumor hypomethylation at 6p21.3 associates with longer time to recurrence of high-grade serous epithelial ovarian cancer

Wang, C., Cicek, M., Charbonneau, B., Kalli, K. R., Armasu, S. M., Larson, M. C., Konecny, G. E., Winterhoff, B., Fan, J. B., Bibikova, M., Chien, J., Shridhar, V., Block, M. S., Hartmann, L. C., Visscher, D. W., Cunningham, J. M., Knutson, K. L., Fridley, B. L. & Goode, E. L., Jun 1 2014, In : Cancer Research. 74, 11, p. 3084-3091 8 p.

Research output: Contribution to journalArticle

Methylation
Recurrence
Neoplasms
Carcinoma
Cluster Analysis
11 Citations (Scopus)

Variation in NF-κB signaling pathways and survival in invasive epithelial ovarian cancer

Block, M. S., Charbonneau, B., Vierkant, R. A., Fogarty, Z., Bamlet, W. R., Pharoah, P. D. P., Chenevix-Trench, G., Rossing, M. A., Cramer, D., Pearce, C. L., Schildkraut, J., Menon, U., Kjaer, S. K., Levine, D. A., Gronwald, J., Culver, H. A., Whittemore, A. S., Karlan, B. Y., Lambrechts, D., Wentzensen, N. & 72 others, Kupryjanczyk, J., Chang-Claude, J., Bandera, E. V., Hogdall, E., Heitz, F., Kaye, S. B., Fasching, P. A., Campbell, I., Goodman, M. T., Pejovic, T., Bean, Y. T., Hays, L. E., Lurie, G., Eccles, D., Hein, A., Beckmann, M. W., Ekici, A. B., Paul, J., Brown, R., Flanagan, J. M., Harter, P., Du Bois, A., Schwaab, I., Hogdall, C. K., Lundvall, L., Olson, S. H., Orlow, I., Paddock, L. E., Rudolph, A., Eilber, U., Dansonka-Mieszkowska, A., Rzepecka, I. K., Ziolkowska-Seta, I., Brinton, L. A., Yang, H., Garcia-Closas, M., Despierre, E., Lambrechts, S., Vergote, I., Walsh, C. S., Lester, J., Sieh, W., McGuire, V., Rothstein, J. H., Ziogas, A., Lubinski, J., Cybulski, C., Menkiszak, J., Jensen, A., Gayther, S. A., Ramus, S. J., Gentry-Maharaj, A., Berchuck, A., Wu, A. H., Pike, M. C., Van Den Berg, D., Terry, K. L., Vitonis, A. F., Ramirez, S. M., Rider, D. N., Knutson, K. L., Sellers, T. A., Phelan, C. M., Doherty, J. A., Johnatty, S. E., De Fazio, A., Song, H., Tyrer, J., Kalli, K. R., Fridley, B. L., Cunningham, J. M. & Goode, E. L., 2014, In : Cancer Epidemiology Biomarkers and Prevention. 23, 7, p. 1421-1427 7 p.

Research output: Contribution to journalArticle

Survival
Confidence Intervals
Histology
Transmembrane Activator and CAML Interactor Protein
Immunity
2013
6 Citations (Scopus)

Enzymatic discovery of a HER-2/neu epitope that generates cross-reactive T cells

Henle, A. M., Erskine, C. L., Benson, L. M., Clynes, R. & Knutson, K. L., Jan 1 2013, In : Journal of Immunology. 190, 1, p. 479-488 10 p.

Research output: Contribution to journalArticle

HLA-A2 Antigen
Epitopes
Proteasome Endopeptidase Complex
Breast Neoplasms
T-Lymphocytes
7 Citations (Scopus)
Cytomegalovirus
Immunity
Rheumatoid Arthritis
Human Herpesvirus 4
Joints
18 Citations (Scopus)

Inherited Variants in Regulatory T Cell Genes and Outcome of Ovarian Cancer

Goode, E. L., DeRycke, M., Kalli, K. R., Oberg, A. L., Cunningham, J. M., Maurer, M. J., Fridley, B. L., Armasu, S. M., Serie, D. J., Ramar, P., Goergen, K., Vierkant, R. A., Rider, D. N., Sicotte, H., Wang, C., Winterhoff, B., Phelan, C. M., Schildkraut, J. M., Weber, R. P., Iversen, E. & 21 others, Berchuck, A., Sutphen, R., Birrer, M. J., Hampras, S., Preus, L., Gayther, S. A., Ramus, S. J., Wentzensen, N., Yang, H. P., Garcia-Closas, M., Song, H., Tyrer, J., Pharoah, P. P. D., Konecny, G., Sellers, T. A., Ness, R. B., Sucheston, L. E., Odunsi, K., Hartmann, L. C., Moysich, K. B. & Knutson, K. L., Jan 30 2013, In : PLoS One. 8, 1, e53903.

Research output: Contribution to journalArticle

ovarian neoplasms
T-cells
Regulatory T-Lymphocytes
Ovarian Neoplasms
Single Nucleotide Polymorphism
65 Citations (Scopus)
Clinical Trials, Phase I
Stem cells
Mesenchymal Stromal Cells
Viruses
Ovarian Neoplasms
96 Citations (Scopus)

Rheumatoid arthritis and cardiovascular disease

Crowson, C., Liao, K. P., Davis, J. M. III., Solomon, D. H., Matteson, E. L., Knutson, K. L., Hlatky, M. A. & Gabriel, S. E., Oct 2013, In : American Heart Journal. 166, 4

Research output: Contribution to journalArticle

Heart Diseases
Rheumatoid Arthritis
Cardiovascular Diseases
Rheumatic Diseases
Inflammation
13 Citations (Scopus)

The epitope integration site for vaccine antigens determines virus control while maintaining efficacy in an engineered cancer vaccine

Pavelko, K. D., Bell, M. P., Karyampudi, L., Hansen, M. J., Allen, K. S., Knutson, K. L. & Pease, L. R., May 2013, In : Molecular Therapy. 21, 5, p. 1087-1095 9 p.

Research output: Contribution to journalArticle

Cancer Vaccines
Theilovirus
Immunotherapy
Picornaviridae
Epitopes

The immune system in breast cancer initiation and progression: Role of epithelial to mesenchymal transition

Knutson, K. L. & Radisky, D. C., Jun 1 2013, Cell and Molecular Biology of Breast Cancer. Humana Press Inc., Vol. 9781627036344. p. 43-64 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Epithelial-Mesenchymal Transition
Immune system
Immune System
Human Mammary Glands
Breast Neoplasms
32 Citations (Scopus)

The immune system in the pathogenesis of ovarian cancer

Bridget, C., Goode, E. L., Kalli, K. R., Knutson, K. L. & DeRycke, M. S., 2013, In : Critical Reviews in Immunology. 33, 2, p. 137-164 28 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Immune System
Immunity
Cytokines
Inborn Genetic Diseases
87 Citations (Scopus)

The ratios of CD8+ T cells to CD4+CD25+ FOXP3+ and FOXP3- T cells correlate with poor clinical outcome in human serous ovarian cancer

Preston, C. C., Maurer, M. J., Oberg, A. L., Visscher, D. W., Kalli, K. R., Hartmann, L. C., Goode, E. L. & Knutson, K. L., Nov 14 2013, In : PLoS One. 8, 11, e80063.

Research output: Contribution to journalArticle

ovarian neoplasms
T-cells
Ovarian Neoplasms
T-lymphocytes
T-Lymphocytes
3 Citations (Scopus)

Toward understanding the genetics of regulatory t cells in ovarian cancer

DeRycke, M. S., Charbonneau, B., Preston, C. C., Kalli, K. R., Knutson, K. L., Rider, D. N. & Goode, E. L., Jun 2013, In : OncoImmunology. 2, 6, e24572.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Immune Evasion
Regulatory T-Lymphocytes
Single Nucleotide Polymorphism
Neoplasms
15 Citations (Scopus)

Utility of progranulin and serum leukocyte protease inhibitor as diagnostic and prognostic biomarkers in ovarian cancer

Carlson, A. M., Maurer, M. J., Goergen, K. M., Kalli, K. R., Erskine, C. L., Behrens, M. D., Knutson, K. L. & Block, M. S., Oct 2013, In : Cancer Epidemiology Biomarkers and Prevention. 22, 10, p. 1730-1735 6 p.

Research output: Contribution to journalArticle

Protease Inhibitors
Ovarian Neoplasms
Leukocytes
Biomarkers
Serum
2012
11 Citations (Scopus)

A profile of immune response to herpesvirus is associated with radiographic joint damage in rheumatoid arthritis

Davis, J. M. III., Knutson, K. L., Skinner, J. A., Strausbauch, M. A., Crowson, C., Therneau, T. M., Wettstein, P. J., Matteson, E. L. & Gabriel, S. E., Jan 31 2012, In : Arthritis Research and Therapy. 14, 1, R24.

Research output: Contribution to journalArticle

Herpesviridae
Cytomegalovirus
Human Herpesvirus 4
Rheumatoid Arthritis
Joints