Julian R Molina, MD, PhD

  • 8583 Citations
  • 38 Scopus h-Index
19962020

Research output per year

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Research Output

  • 8583 Citations
  • 38 Scopus h-Index
  • 112 Article
  • 2 Review article
  • 1 Chapter
  • 1 Editorial
2020

A Randomized Double-Blind Phase II Study of the Seneca Valley Virus (NTX-010) versus Placebo for Patients with Extensive-Stage SCLC (ES SCLC) Who Were Stable or Responding after at Least Four Cycles of Platinum-Based Chemotherapy: North Central Cancer Treatment Group (Alliance) N0923 Study

Schenk, E. L., Mandrekar, S. J., Dy, G. K., Aubry, M. C., Tan, A. D., Dakhil, S. R., Sachs, B. A., Nieva, J. J., Bertino, E., Lee Hann, C., Schild, S. E., Wadsworth, T. W., Adjei, A. A. & Molina, J. R., Jan 2020, In : Journal of Thoracic Oncology. 15, 1, p. 110-119 10 p.

Research output: Contribution to journalArticle

2019

A Phase II Study of Pazopanib in Patients with Malignant Pleural Mesothelioma: NCCTG N0623 (Alliance)

Parikh, K., Mandrekar, S. J., Allen-Ziegler, K., Esplin, B., Tan, A. D., Marchello, B., Adjei, A. A. & Molina, J. R., Jan 1 2019, (Accepted/In press) In : Oncologist.

Research output: Contribution to journalArticle

Loss of ATRX expression predicts worse prognosis in pulmonary carcinoid tumors

Terra, S. B. S. P., Xie, H., Boland, J. M., Mansfield, A. S., Molina, J. R. & Roden, A. C., Dec 2019, In : Human Pathology. 94, p. 78-85 8 p.

Research output: Contribution to journalArticle

Non–Small Cell Lung Cancer: Epidemiology, Screening, Diagnosis, and Treatment

Duma, N., Santana-Davila, R. & Molina, J. R., Aug 1 2019, In : Mayo Clinic proceedings. 94, 8, p. 1623-1640 18 p.

Research output: Contribution to journalReview article

Open Access
9 Scopus citations

Oncolytic Measles Virotherapy and Opposition to Measles Vaccination

Russell, S. J., Babovic-Vuksanovic, D., Bexon, A., Cattaneo, R., Dingli, D., Dispenzieri, A., Deyle, D. R., Federspiel, M. J., Fielding, A., Galanis, E., Lacy, M. Q., Leibovich, B. C., Liu, M. C., Muñoz-Alía, M., Miest, T. C., Molina, J. R., Mueller, S., Okuno, S. H., Packiriswamy, N., Peikert, T. & 6 others, Raffel, C., Van Rhee, F., Ungerechts, G., Young, P. R., Zhou, Y. & Peng, K. W., Jan 1 2019, In : Mayo Clinic proceedings.

Research output: Contribution to journalReview article

Open Access
1 Scopus citations

PFKFB3 inhibition reprograms malignant pleural mesothelioma to nutrient stress-induced macropinocytosis and ER stress as independent binary adaptive responses

Sarkar Bhattacharya, S., Thirusangu, P., Jin, L., Roy, D., Jung, D., Xiao, Y., Staub, J., Roy, B., Molina, J. R. & Shridhar, V., Oct 1 2019, In : Cell Death and Disease. 10, 10, 725.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Treatment-Related Adverse Events of PD-1 and PD-L1 Inhibitors in Clinical Trials: A Systematic Review and Meta-analysis

Wang, Y., Zhou, S., Yang, F., Qi, X., Wang, X., Guan, X., Shen, C., Duma, N., Vera Aguilera, J., Chintakuntlawar, A., Price, K. A., Molina, J. R., Pagliaro, L. C., Halfdanarson, T. R., Grothey, A. F., Markovic, S. N., Nowakowski, G. S., Ansell, S. M. & Wang, M. L., Jan 1 2019, In : JAMA Oncology.

Research output: Contribution to journalArticle

43 Scopus citations

Use of archival versus newly collected tumor samples for assessing PD-L1 expression and overall survival: An updated analysis of keynote-010 trial

Herbst, R. S., Baas, P., Perez-Gracia, J. L., Felip, E., Kim, D. W., Han, J. Y., Molina, J. R., Kim, J. H., Dubos Arvis, C., Ahn, M. J., Majem, M., Fidler, M. J., Surmont, V., De Castro, G., Garrido, M., Shentu, Y., Emancipator, K., Samkari, A., Jensen, E. H., Lubiniecki, G. M. & 1 others, Garon, E. B., Feb 1 2019, In : Annals of Oncology. 30, 2, p. 281-289 9 p.

Research output: Contribution to journalArticle

14 Scopus citations
2018
1 Scopus citations
1 Scopus citations

BAP1 loss is unusual in well-differentiated papillary mesothelioma and may predict development of malignant mesothelioma

Lee, H. E., Molina, J. R., Sukov, W. R., Roden, A. & Yi, E. S., Sep 1 2018, In : Human Pathology. 79, p. 168-176 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Carcinoid Heart Disease in Patients With Bronchopulmonary Carcinoid

De Jesus, T., Luis, S. A., Ryu, J. H., Molina, J. R., Connolly, H. M., Maleszewski, J. & Pellikka, P., Oct 1 2018, In : Journal of Thoracic Oncology. 13, 10, p. 1602-1605 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

Characterization of Comorbidities Limiting the Recruitment of Patients in Early Phase Clinical Trials

Duma, N., Kothadia, S. M., Azam, T. U., Yadav, S., Paludo, J., Vera Aguilera, J., Gonzalez Velez, M., Halfdanarson, T. R., Molina, J. R., Hubbard, J. M., Go, R. S., Mansfield, A. & Adjei, A., Jan 1 2018, (Accepted/In press) In : Oncologist.

Research output: Contribution to journalArticle

1 Scopus citations

Identification and Development of a Lung Adenocarcinoma PDX Model With STRN-ALK Fusion

Ren, H., Hou, X., Eiken, P. W., Zhang, J., Pierson, K. E., Nair, A. A., Davila, J. I., Kovarikova, H., Jang, J. S., Johnson, S. H., Molina, J. R., Marks, R. S., Yang, P., Yi, J. E., Mansfield, A. & Jen, J., Jan 1 2018, (Accepted/In press) In : Clinical Lung Cancer.

Research output: Contribution to journalArticle

1 Scopus citations

NCCN guidelines® insights: Small cell lung cancer, version 2.2018 featured updates to the NCCN guidelines

Kalemkerian, G. P., Loo, B. W., Akerley, W., Attia, A., Bassetti, M., Boumber, Y., Decker, R., Dobelbower, M. C., Dowlati, A., Downey, R. J., Florsheim, C., Ganti, A. K. P., Grecula, J. C., Gubens, M. A., Hann, C. L., Hayman, J. A., Heist, R. S., Koczywas, M., Merritt, R. E., Mohindra, N. & 11 others, Molina, J. R., Moran, C. A., Morgensztern, D., Pokharel, S., Portnoy, D. C., Rhodes, D., Rusthoven, C., Santana-Davila, R., Williams, C. C., Hoffmann, K. G. & Hughes, M., Oct 1 2018, In : JNCCN Journal of the National Comprehensive Cancer Network. 16, 10, p. 1171-1182 12 p.

Research output: Contribution to journalArticle

21 Scopus citations

Nomogram prediction of overall survival for patients with non-small-cell lung cancer incorporating pretreatment peripheral blood markers

Xie, D., Allen, M. S., Marks, R. S., Jiang, G., Sun, Z. D., Nichols, F., Zhang, M., Chen, C., Aubry, M. C., Jatoi, A., Garces, Y. I., Mansfield, A., Wigle, D. A., Molina, J. R., Deschamps, C. & Yang, P., Jun 1 2018, In : European Journal of Cardio-thoracic Surgery. 53, 6, p. 1214-1222 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Pathways impacted by genomic alterations in pulmonary carcinoid tumors

Asiedu, M. K., Thomas, C. F., Dong, J., Schulte, S. C., Khadka, P., Sun, Z. D., Kosari, F., Jen, J., Molina, J. R., Vasmatzis, G., Kuang, R., Aubry, M. C., Yang, P. & Wigle, D. A., Apr 1 2018, In : Clinical Cancer Research. 24, 7, p. 1691-1704 14 p.

Research output: Contribution to journalArticle

12 Scopus citations

Sarcomatoid Carcinoma of the Lung: The Mayo Clinic Experience in 127 Patients

Maneenil, K., Xue, Z., Liu, M., Boland, J., Wu, F., Stoddard, S. M., Molina, J. R. & Yang, P., Jan 1 2018, (Accepted/In press) In : Clinical Lung Cancer.

Research output: Contribution to journalArticle

9 Scopus citations

Smoking, sex, and non–Small cell lung cancer: Steroid hormone receptors in tumor tissue (S0424)

Cheng, T. Y. D., Darke, A. K., Redman, M. W., Zirpoli, G. R., Davis, W., Ondracek, R. P., Bshara, W., Omilian, A. R., Kratzke, R., Reid, M. E., Molina, J. R., Kolesar, J. M., Chen, Y., MacRae, R. M., Moon, J., Mack, P., Gandara, D. R., Kelly, K., Santella, R. M., Albain, K. S. & 1 others, Ambrosone, C. B., Jan 1 2018, In : Journal of the National Cancer Institute. 110, 7, p. 734-742 9 p.

Research output: Contribution to journalArticle

4 Scopus citations
2017

A phase I study of cilengitide and paclitaxel in patients with advanced solid tumors

Haddad, T. C., Qin, R., Lupu, R., Satele, D., Eadens, M., Goetz, M. P., Erlichman, C. & Molina, J. R., Jun 1 2017, In : Cancer Chemotherapy and Pharmacology. 79, 6, p. 1221-1227 7 p.

Research output: Contribution to journalArticle

14 Scopus citations

A regulatory circuit composed of DNA methyltransferases and receptor tyrosine kinases controls lung cancer cell aggressiveness

Yan, F., Shen, N., Pang, J., Zhao, N., Deng, B., Li, B., Yang, Y. D., Yang, P., Molina, J. R. & Liu, S., Dec 14 2017, In : Oncogene. 36, 50, p. 6919-6928 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

Digit-a tool for detection and identification of genomic interchromosomal translocations

Meier, R., Graw, S., Beyerlein, P., Koestler, D., Molina, J. R. & Chien, J., May 19 2017, In : Nucleic Acids Research. 45, 9, p. e72

Research output: Contribution to journalArticle

Editorial: Pleural recurrence of thymoma-what is the value of intra-thoracic chemo-hyperthermia?

Roden, A. & Molina, J. R., Oct 1 2017, In : Journal of Thoracic Disease. 9, 10, p. 3583-3586 4 p.

Research output: Contribution to journalEditorial

Management of Multifocal Lung Cancer: Results of a Survey

Leventakos, K., Peikert, T. D., Midthun, D. E., Molina, J. R., Blackmon, S., Nichols, F. C., Garces, Y. I., Hallemeier, C., Murphy, S. J., Vasmatzis, G., Kratz, S. L., Holland, W. P., Thomas, C. F., Mullon, J. J., Shen, K. R., Cassivi, S. D., Marks, R. S., Aubry, M. C., Adjei, A., Yang, P. & 4 others, Allen, M. S., Edell, E., Wigle, D. A. & Mansfield, A., 2017, (Accepted/In press) In : Journal of Thoracic Oncology.

Research output: Contribution to journalArticle

8 Scopus citations

Phase III Randomized, placebo-controlled, double-blind trial of celecoxib in addition to standard chemotherapy for advanced non-small-cell lung cancer with cyclooxygenase-2 overexpression: CALGB 30801 (Alliance)

Edelman, M. J., Wang, X., Hodgson, L., Cheney, R. T., Baggstrom, M. Q., Thomas, S. P., Gajra, A., Bertino, E., Reckamp, K. L., Molina, J. R., Schiller, J. H., Mitchell-Richards, K., Friedman, P. N., Ritter, J., Milne, G., Hahn, O. M., Stinchcombe, T. E. & Vokes, E. E., Jul 1 2017, In : Journal of Clinical Oncology. 35, 19, p. 2184-2192 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

Survival in Response to Multimodal Therapy in Anaplastic Thyroid Cancer

Prasongsook, N., Kumar, A., Chintakuntlawar, A., Foote, R. L., Kasperbauer, J., Molina, J. R., Garces, Y. I., Ma, D., Wittich, M. A. N., Rubin, J., Richardson, R., Morris, J., Hay, I. D., Fatourechi, V., McIver, B., Ryder, M., Thompson, G., Grant, C., Richards, M., Sebo, T. J. & 5 others, Rivera, M., Suman, V. J., Jenkins, S. M., Smallridge, R. C. & Bible, K. C., Dec 1 2017, In : The Journal of clinical endocrinology and metabolism. 102, 12, p. 4506-4514 9 p.

Research output: Contribution to journalArticle

20 Scopus citations
2016

88P: Use of brain imaging in the management of patients with lymph node negative multifocal lung cancer

Leventakos, K., Mansfield, A., Blackmon, S., Cassivi, S., Shen, R., Nichols, F. C., Molina, J. R., Allen, M. S., Aubry, M. C. & Wigle, D. A., Apr 1 2016, In : Journal of Thoracic Oncology. 11, 4, p. S93-S94

Research output: Contribution to journalArticle

1 Scopus citations

A first-in-human phase i study of the oral p38 MAPK inhibitor, ralimetinib (LY2228820 Dimesylate), in patients with advanced cancer

Patnaik, A., Haluska, P., Tolcher, A. W., Erlichman, C., Papadopoulos, K. P., Lensing, J. L., Beeram, M., Molina, J. R., Rasco, D. W., Arcos, R. R., Kelly, C. S., Wijayawardana, S. R., Zhang, X., Stancato, L. F., Bell, R., Shi, P., Kulanthaivel, P., Pitou, C., Mulle, L. B., Farrington, D. L. & 2 others, Chan, E. M. & Goetz, M. P., Mar 1 2016, In : Clinical Cancer Research. 22, 5, p. 1095-1102 8 p.

Research output: Contribution to journalArticle

32 Scopus citations

A genetic cell context-dependent role for ZEB1 in lung cancer

Zhang, T., Guo, L., Creighton, C. J., Lu, Q., Gibbons, D. L., Yi, E. S., Deng, B., Molina, J. R., Sun, Z. D., Yang, P. & Yang, Y. D., Jul 26 2016, In : Nature Communications. 7, 12231.

Research output: Contribution to journalArticle

30 Scopus citations

C-Met expression and MET amplification in malignant pleural mesothelioma

Bois, M. C., Mansfield, A., Sukov, W. R., Jenkins, S. M., Moser, J. C., Sattler, C. A., Smith, C. Y., Molina, J. R., Peikert, T. D. & Roden, A., Aug 1 2016, In : Annals of Diagnostic Pathology. 23, p. 1-7 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Comprehensive genomic profiling identifies a subset of Crizotinib- responsive ALK-rearranged non-small cell lung cancer not detected by fluorescence in situ hybridization

Ali, S. M., Hensing, T., Schrock, A. B., Allen, J., Sanford, E., Gowen, K., Kulkarni, A., He, J., Suh, J. H., Lipson, D., Elvin, J. A., Yelensky, R., Chalmers, Z., Chmielecki, J., Peled, N., Klempner, S. J., Firozvi, K., Frampton, G. M., Molina, J. R., Amenon, S. & 14 others, Brahmer, J. R., MacMahon, H., Nowak, J., Ignatius Ou, S. H., Zauderer, M., Ladanyi, M., Zakowski, M., Fischbach, N., Ross, J. S., Stephens, P. J., Miller, V. A., Wakelee, H., Ganesan, S. & Salgia, R., Jun 1 2016, In : Oncologist. 21, 6, p. 762-770 9 p.

Research output: Contribution to journalArticle

63 Scopus citations

DNA damage-induced ephrin-B2 reverse signaling promotes chemoresistance and drives EMT in colorectal carcinoma harboring mutant p53

Alam, S. K., Yadav, V. K., Bajaj, S., Datta, A., Dutta, S. K., Bhattacharyya, M., Bhattacharya, S., Debnath, S., Roy, S., Boardman, L. A., Smyrk, T. C., Molina, J. R., Chakrabarti, S., Chowdhury, S., Mukhopadhyay, D. & Roychoudhury, S., Apr 1 2016, In : Cell Death and Differentiation. 23, 4, p. 707-722 16 p.

Research output: Contribution to journalArticle

39 Scopus citations

Elevated cellular PD1/PD-L1 expression confers acquired resistance to cisplatin in small cell lung cancer cells

Yan, F., Pang, J., Peng, Y., Molina, J. R., Yang, P. & Liu, S., Sep 1 2016, In : PLoS One. 11, 9, e0162925.

Research output: Contribution to journalArticle

23 Scopus citations

Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): A randomised controlled trial

Herbst, R. S., Baas, P., Kim, D. W., Felip, E., Pérez-Gracia, J. L., Han, J. Y., Molina, J. R., Kim, J. H., Arvis, C. D., Ahn, M. J., Majem, M., Fidler, M. J., De Castro, G., Garrido, M., Lubiniecki, G. M., Shentu, Y., Im, E., Dolled-Filhart, M. & Garon, E. B., Apr 9 2016, In : The Lancet. 387, 10027, p. 1540-1550 11 p.

Research output: Contribution to journalArticle

2409 Scopus citations

Response of uveal metastases to alk inhibitors in alk-positive non-small-cell lung cancer

Abdellatief, A., Molina, J. R. & Pulido, J. S., Jan 1 2016, In : Retinal Cases and Brief Reports. 10, 1, p. 37-40 4 p.

Research output: Contribution to journalArticle

2015

Dopamine D2 receptor agonists inhibit lung cancer progression by reducing angiogenesis and tumor infiltrating myeloid derived suppressor cells

Hoeppner, L. H., Wang, Y., Sharma, A., Javeed, N., Van Keulen, V. P., Wang, E., Yang, P., Roden, A., Peikert, T. D., Molina, J. R. & Mukhopadhyay, D., Jan 1 2015, In : Molecular Oncology. 9, 1, p. 270-281 12 p.

Research output: Contribution to journalArticle

25 Scopus citations

First-in-human study of PF-05212384 (PKI-587), a small-molecule, intravenous, dual inhibitor of PI3K and mTOR in patients with advanced cancer

Shapiro, G. I., Bell-McGuinn, K. M., Molina, J. R., Bendell, J., Spicer, J., Kwak, E. L., Pandya, S. S., Millham, R., Borzillo, G., Pierce, K. J., Han, L., Houk, B. E., Gallo, J. D., Alsina, M., Braña, I. & Tabernero, J., Apr 15 2015, In : Clinical Cancer Research. 21, 8, p. 1888-1895 8 p.

Research output: Contribution to journalArticle

48 Scopus citations
37 Scopus citations

Pulmonary artery agenesis associated with emphysema and multiple invasive non-small cell lung cancers

Makdisi, G., Edell, E., Maleszewski, J., Molina, J. R. & Deschamps, C., Jun 1 2015, In : Annals of Thoracic Surgery. 99, 6, p. 2192-2195 4 p.

Research output: Contribution to journalArticle

2 Scopus citations
19 Scopus citations
2014

Adjuvant chemoradiation therapy with high-dose versus weekly cisplatin for resected, locally-advanced HPV/p16-positive and negative head and neck squamous cell carcinoma

Geiger, J. L., Lazim, A. F., Walsh, F. J., Foote, R. L., Moore, E. J., Okuno, S. H., Olsen, K. D., Kasperbauer, J., Price, D. L., Garces, Y. I., Ma, D. J., Neben-Wittich, M. A., Molina, J. R., Garcia, J. J. & Price, K. A. R., 2014, In : Oral Oncology. 50, 4, p. 311-318 8 p.

Research output: Contribution to journalArticle

33 Scopus citations

A multicenter phase 2 trial of pazopanib in metastatic and progressive medullary thyroid carcinoma: MC057H

Bible, K. C., Suman, V. J., Molina, J. R., Smallridge, R. C., Maples, W. J., Menefee, M. E., Rubin, J., Karlin, N., Sideras, K., Morris, J. C., McIver, B., Hay, I. D., Fatourechi, V., Burton, J. K., Webster, K. P., Bieber, C., Traynor, A. M., Flynn, P. J., Goh, B. C., Isham, C. R. & 2 others, Harris, P. & Erlichman, C., 2014, In : Journal of Clinical Endocrinology and Metabolism. 99, 5, p. 1687-1693 7 p.

Research output: Contribution to journalArticle

57 Scopus citations

A Phase I/II Study of Bortezomib in Combination with Paclitaxel, Carboplatin and Concurrent Thoracic Radiation Therapy for Non-Small Cell Lung Cancer: NCCTG-N0321

Zhao, Y., Foster, N. R., Meyers, J. P., Thomas, S. P., Northfelt, D. W., Rowland, K. M., Mattar, B. I., Johnson, D. B., Molina, J. R., Mandrekar, S. J., Schild, S. E., Bearden, J. D., Aubry, M. C. & Adjei, A., Sep 22 2014, (Accepted/In press) In : Journal of Thoracic Oncology.

Research output: Contribution to journalArticle

21 Scopus citations

A phase II trial of the Src-kinase inhibitor saracatinib after four cycles of chemotherapy for patients with extensive stage small cell lung cancer: NCCTG trial N-0621

Molina, J. R., Foster, N. R., Reungwetwattana, T., Nelson, G. D., Grainger, A. V., Steen, P. D., Stella, P. J., Marks, R. S., Wright, J. & Adjei, A., 2014, In : Lung Cancer. 85, 2, p. 245-250 6 p.

Research output: Contribution to journalArticle

22 Scopus citations

Clinical biomarkers of pulmonary carcinoid tumors in never smokers via profiling miRNA and target mRNA

Deng, B., Molina, J. R., Aubry, M. C., Sun, Z. D., Wang, L., Eckloff, B. W., Vasmatzis, G., You, M., Wieben, E. D., Jen, J., Wigle, D. A. & Yang, P., Jul 9 2014, In : Cell and Bioscience. 4, 1, 35.

Research output: Contribution to journalArticle

6 Scopus citations

Concurrent MCL1 and JUN amplification in pseudomyxoma peritonei: A comprehensive genetic profiling and survival analysis

Sio, T. T., Mansfield, A., Grotz, T. E., Graham, R., Molina, J. R., Que, F. & Miller, R. C., 2014, In : Journal of Human Genetics. 59, 3, p. 124-128 5 p.

Research output: Contribution to journalArticle

17 Scopus citations

NCCTG N0821 (Alliance): A phase ii first-line study of pemetrexed, carboplatin, and bevacizumab in elderly patients with advanced nonsquamous non-small-cell lung cancer with good performance status

Dy, G. K., Molina, J. R., Qi, Y., Ansari, R., Thomas, S., Ross, H. J., Soori, G., Anderson, D., Christine Aubry, M., Meyers, J., Adjei, A. A., Mandrekar, S. J. & Adjei, A., 2014, In : Journal of Thoracic Oncology. 9, 8, p. 1146-1153 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Restoration ofmiR-101 suppresses lung tumorigenesis through inhibition of DNMT3a-dependent DNA methylation

Yan, F., Shen, N., Pang, J., Xie, D., Deng, B., Molina, J. R., Yang, P. & Liu, S., Jan 1 2014, In : Cell Death and Disease. 5, 9, e1413.

Research output: Contribution to journalArticle

42 Scopus citations
2013

A randomized phase II study of gemcitabine and carboplatin with or without cediranib as first-line therapy in advanced non-small-cell lung cancer: North central cancer treatment group study N0528

Adjei, A., Dy, G. K., Mandrekar, S. J., Nelson, G. D., Meyers, J. P., Adjei, A. A., Ross, H. J., Ansari, R. H., Lyss, A. P., Stella, P. J., Schild, S. E. & Molina, J. R., Jan 2013, In : Journal of Thoracic Oncology. 8, 1, p. 79-88 10 p.

Research output: Contribution to journalArticle

34 Scopus citations