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Research Output 1979 2019

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2009
14 Citations (Scopus)

B-type natriuretic peptide 8-32, which is produced from mature BNP 1-32 by the metalloprotease meprin A, has reduced bioactivity

Boerrigter, G., Costello-Boerrigter, L. C., Harty, G. J., Huntley, B. K., Cataliotti, A., Lapp, H. & Burnett, J. C. J., Jun 2009, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 296, 6

Research output: Contribution to journalArticle

meprin A
Brain Natriuretic Peptide
Metalloproteases
peptide 32
46 Citations (Scopus)
Brain Natriuretic Peptide
Peptides
Digestion
Assays
Heart Failure
17 Citations (Scopus)

Designer natriuretic peptides

Lee, C. Y. W., Lieu, H. & Burnett, J. C. J., Jan 1 2009, In : Journal of Investigative Medicine. 57, 1, p. 18-21 4 p.

Research output: Contribution to journalArticle

Natriuretic Peptides
Peptides
Amino Acid Substitution
Substitution reactions
Pharmacology

Designer natriuretic peptides

Lee, C. Y. W., Lieu, H. & Burnett, J. C. J., Jan 2009, In : Journal of Investigative Medicine. 57, 1, p. 18-21 4 p.

Research output: Contribution to journalArticle

Natriuretic Peptides
Peptides
Amino Acid Substitution
Substitution reactions
Pharmacology
55 Citations (Scopus)

Effects of tolvaptan on dyspnoea relief from the EVEREST trials

Pang, P. S., Konstam, M. A., Krasa, H. B., Swedberg, K., Zannad, F., Blair, J. E. A., Zimmer, C., Teerlink, J. R., Maggioni, A. P., Burnett, J. C. J., Grinfeld, L., Ouyang, J., Udelson, J. E. & Gheorghiade, M., Sep 2009, In : European Heart Journal. 30, 18, p. 2233-2240 8 p.

Research output: Contribution to journalArticle

Dyspnea
Therapeutics
Heart Failure
tolvaptan
Clinical Trials

Erratum: Designer natriuretic peptides (J Investigat Med. (2009) 57 (18-21)).

Lee, C. Y. W., Lieu, H. & Burnett, J. C. J., Feb 2009, In : Journal of Investigative Medicine. 57, 2, p. 487 1 p.

Research output: Contribution to journalArticle

Natriuretic Peptides
5 Citations (Scopus)

Ethical issues in cardiovascular research involving humans

Frye, R. L., Simari, R. D., Gersh, B. J., Burnett, J. C. J., Brumm, S., Myerle, K., Jaffe, A. S., Holmes, D., Lerman, A. & Terzic, A., Nov 2009, In : Circulation. 120, 21, p. 2113-2121 9 p.

Research output: Contribution to journalArticle

Therapeutic Misconception
Human Experimentation
Conflict of Interest
Privacy
Informed Consent
18 Citations (Scopus)

Local Renal Delivery of a Natriuretic Peptide. A Renal-Enhancing Strategy for B-Type Natriuretic Peptide in Overt Experimental Heart Failure

Chen, H. H., Cataliotti, A., Schirger, J. A., Martin, F. L., Harstad, L. K. & Burnett, J. C. J., Apr 14 2009, In : Journal of the American College of Cardiology. 53, 15, p. 1302-1308 7 p.

Research output: Contribution to journalArticle

Natriuretic Peptides
Brain Natriuretic Peptide
Heart Failure
Kidney
Glomerular Filtration Rate
41 Citations (Scopus)

Low-dose nesiritide in human anterior myocardial infarction suppresses aldosterone and preserves ventricular function and structure: A proof of concept study

Chen, H. H., Martin, F. L., Gibbons, R. J., Schirger, J. A., Wright, R. S., Schears, R. M., Redfield, M. M., Simari, R. D., Lerman, A., Cataliotti, A. & Burnett, J. C. J., Aug 2009, In : Heart. 95, 16, p. 1315-1319 5 p.

Research output: Contribution to journalArticle

Ventricular Function
Brain Natriuretic Peptide
Aldosterone
Myocardial Infarction
Stroke Volume
31 Citations (Scopus)

Modulation of cGMP in heart failure: A new therapeutic paradigm

Boerrigter, G., Lapp, H. & Burnett, J. C. J., 2009, In : Handbook of Experimental Pharmacology. 191, p. 485-506 22 p.

Research output: Contribution to journalArticle

Guanylate Cyclase
Cyclic GMP
Heart Failure
Modulation
Natriuretic Peptides
47 Citations (Scopus)

Natriuretic Peptides in the Diagnosis and Management of Chronic Heart Failure

Boerrigter, G., Costello-Boerrigter, L. C. & Burnett, J. C. J., Oct 2009, In : Heart Failure Clinics. 5, 4, p. 501-514 14 p.

Research output: Contribution to journalArticle

Natriuretic Peptides
Heart Failure
Systems Biology
Single Nucleotide Polymorphism
Cardiovascular Diseases
29 Citations (Scopus)
Natriuretic Peptides
Brain Natriuretic Peptide
Heart Failure
Hazards
Hospitalization
79 Citations (Scopus)

Pharmacodynamics of a novel designer natriuretic peptide, CD-NP, in a first-in-human clinical trial in healthy subjects

Lee, C. Y. W., Chen, H. H., Lisy, O., Swan, S., Cannon, C., Lieu, H. D. & Burnett, J. C. J., Jun 2009, In : Journal of Clinical Pharmacology. 49, 6, p. 668-673 6 p.

Research output: Contribution to journalArticle

Natriuretic Peptides
Healthy Volunteers
Clinical Trials
C-Type Natriuretic Peptide
Hypotension
28 Citations (Scopus)

Pharmacology of vasopressin antagonists

Costello-Boerrigter, L. C., Boerrigter, G. & Burnett, J. C. J., 2009, In : Heart Failure Reviews. 14, 2, p. 75-82 8 p.

Research output: Contribution to journalArticle

Vasopressin Receptors
Pharmacology
Water
Aquaporin 2
Aquaporins
11 Citations (Scopus)

Prognostic Value of Multiple Biomarkers in American Indians Free of Clinically Overt Cardiovascular Disease (from the Strong Heart Study)

Kizer, J. R., Krauser, D. G., Rodeheffer, R. J., Burnett, J. C. J., Okin, P. M., Roman, M. J., Umans, J. G., Best, L. G., Lee, E. T. & Devereux, R. B., Jul 15 2009, In : American Journal of Cardiology. 104, 2, p. 247-253 7 p.

Research output: Contribution to journalArticle

North American Indians
Cardiovascular Diseases
Biomarkers
Albumins
Creatinine
2 Citations (Scopus)

Response to Cardiac Resynchronization Therapy Improves Renal Function: Importance of Forward and Backward Failure

Boerrigter, G., Costello-Boerrigter, L. C., Abraham, W. T., St. John Sutton, M. G., Heublein, D. M., Kruger, K. M., Hill, M. R. S., McCullough, P. A. & Burnett, J. C. J., Feb 2009, In : Journal of Cardiac Failure. 15, 1, p. 79-80 2 p.

Research output: Contribution to journalArticle

Cardiac Resynchronization Therapy
Kidney
13 Citations (Scopus)

Role for precursor Pro-B type natriuretic peptide in assessing response to therapy and prognosis in patients with decompensated heart failure treated with nesiritide

Miller, W. L., Burnett, J. C. J., Hartman, K. A., Hodge, D. O., Giuliani, I., Minard, F., Larue, C. & Jaffe, A. S., Aug 11 2009, In : Clinica Chimica Acta. 406, 1-2, p. 119-123 5 p.

Research output: Contribution to journalArticle

Brain Natriuretic Peptide
Heart Failure
Therapeutics
Biomarkers
Hospital Mortality
14 Citations (Scopus)

Soluble guanylate cyclase: Not a dull enzyme

Boerrigter, G. & Burnett, J. C. J., Jun 2 2009, In : Circulation. 119, 21, p. 2752-2754 3 p.

Research output: Contribution to journalArticle

Vasomotor System
Morpholines
Pyrazoles
Pyridines
Pyrimidines
60 Citations (Scopus)

Weight changes after hospitalization for worsening heart failure and subsequent re-hospitalization and mortality in the EVEREST trial

Blair, J. E. A., Khan, S., Konstam, M. A., Swedberg, K., Zannad, F., Burnett, J. C. J., Grinfeld, L., Maggioni, A. P., Udelson, J. E., Zimmer, C. A., Ouyang, J., Chen, C. F. & Gheorghiade, M., Jul 2009, In : European Heart Journal. 30, 13, p. 1666-1673 8 p.

Research output: Contribution to journalArticle

Hospitalization
Heart Failure
Weights and Measures
Mortality
Body Weight
2010
20 Citations (Scopus)

A novel atrial natriuretic peptide based therapeutic in experimental angiotensin II mediated acute hypertension

McKie, P., Cataliotti, A., Boerrigter, G., Chen, H. H., Sangaralingham, S. J., Martin, F. L., Ichiki, T. & Burnett, J. C. J., Dec 2010, In : Hypertension. 56, 6, p. 1152-1159 8 p.

Research output: Contribution to journalArticle

Atrial Natriuretic Factor
Angiotensin II
Hypertension
Therapeutics
Natriuretic Peptides
25 Citations (Scopus)

A novel chimeric natriuretic peptide reduces cardiomyocyte hypertrophy through the NHE-1-calcineurin pathway

Kilić, A., Rajapurohitam, V., Sandberg, S. M., Zeidan, A., Hunter, J. C., Said Faruq, N., Lee, C. Y., Burnett, J. C. J. & Karmazyn, M., Dec 1 2010, In : Cardiovascular Research. 88, 3, p. 434-442 9 p.

Research output: Contribution to journalArticle

Natriuretic Peptides
Calcineurin
Cardiac Myocytes
Hypertrophy
Cyclic GMP
13 Citations (Scopus)

B-type natriuretic peptide and extracellular matrix protein interactions in human cardiac fibroblasts

Huntley, B. K., Ichiki, T., Sangaralingham, S. J., Chen, H. H. & Burnett, J. C. J., Oct 2010, In : Journal of Cellular Physiology. 225, 1, p. 251-255 5 p.

Research output: Contribution to journalArticle

Extracellular Matrix Proteins
Brain Natriuretic Peptide
Cyclic GMP
Fibroblasts
Fibronectins
32 Citations (Scopus)
Guanylate Cyclase-Coupled Receptors
Natriuretic Peptides
C-Type Natriuretic Peptide
Brain Natriuretic Peptide
Pressure effects
2 Citations (Scopus)
Predictive Value of Tests
Brain Natriuretic Peptide
Electrocardiography
Biomarkers
Myocardial Infarction
15 Citations (Scopus)

Improving limits of detection for B-type natriuretic peptide using PC-IDMS: An application of the ALiPHAT strategy

Shuford, C. M., Comins, D. L., Whitten, J. L., Burnett, J. C. J. & Muddiman, D. C., 2010, In : Analyst. 135, 1, p. 36-41 6 p.

Research output: Contribution to journalArticle

Brain Natriuretic Peptide
Alkylation
peptide
Limit of Detection
tagging
51 Citations (Scopus)

Mineralocorticoid accelerates transition to heart failure with preserved ejection fraction via "nongenomic effects"

Mohammed, S. F., Ohtani, T., Korinek, J., Lam, C. S. P., Larsen, K., Simari, R. D., Valencik, M. L., Burnett, J. C. J. & Redfield, M. M., Jul 27 2010, In : Circulation. 122, 4, p. 370-378 9 p.

Research output: Contribution to journalArticle

Mineralocorticoids
Mineralocorticoid Receptors
Desoxycorticosterone
Heart Failure
Hypertrophy
50 Citations (Scopus)

National heart, lung, and blood institute working group on emergency department management of acute heart failure: Research challenges and opportunities

Peacock, W. F., Braunwald, E., Abraham, W., Albert, N., Burnett, J. C. J., Christenson, R., Collins, S., Diercks, D., Fonarow, G., Hollander, J., Kellerman, A., Gheorghiade, M., Kirk, D., Levy, P., Maisel, A., Massie, B. M., O'Connor, C., Pang, P., Shah, M., Sopko, G. & 3 others, Stevenson, L., Storrow, A. & Teerlink, J., Jul 27 2010, In : Journal of the American College of Cardiology. 56, 5, p. 343-351 9 p.

Research output: Contribution to journalArticle

National Heart, Lung, and Blood Institute (U.S.)
Hospital Emergency Service
Heart Failure
Research
Biotechnology
16 Citations (Scopus)
Neprilysin
Natriuretic Peptides
Pharmacogenetics
Genes
Isoenzymes
54 Citations (Scopus)

Progression of preclinical diastolic dysfunction to the development of symptoms

Correa De Sa, D. D., Hodge, D. O., Slusser, J. P., Redfield, M. M., Simari, R. D., Burnett, J. C. J. & Chen, H. H., Apr 2010, In : Heart. 96, 7, p. 528-532 5 p.

Research output: Contribution to journalArticle

Heart Failure
Dyspnea
Hypertension
Fatigue
Echocardiography
2 Citations (Scopus)

Regulation of circulating progenitor cells in left ventricular dysfunction.

Boilson, B. A., Larsen, K., Harbuzariu, A., Delacroix, S., Korinek, J., Froehlich, H., Bailey, K. R., Scott, C. G., Shapiro, B. P., Boerrigter, G., Chen, H. H., Redfield, M. M., Burnett, J. C. J. & Simari, R. D., Sep 1 2010, In : Circulation. Heart failure. 3, 5, p. 635-642 8 p.

Research output: Contribution to journalArticle

Left Ventricular Dysfunction
Stem Cells
Desoxycorticosterone
Mineralocorticoids
Acetates
21 Citations (Scopus)

Renal and anti-aldosterone actions of vasopressin-2 receptor antagonism and B-type natriuretic peptide in experimental heart failure

Costello-Boerrigter, L. C., Boerrigter, G., Cataliotti, A., Harty, G. J. & Burnett, J. C. J., May 2010, In : Circulation: Heart Failure. 3, 3, p. 412-419 8 p.

Research output: Contribution to journalArticle

Vasopressin Receptors
Brain Natriuretic Peptide
Aldosterone
Heart Failure
Kidney
78 Citations (Scopus)
Brain Natriuretic Peptide
Heart Failure
Healthy Volunteers
Stroke
Myocardial Infarction
18 Citations (Scopus)

Utilizing spectral counting to quantitatively characterize tandem removal of abundant proteins (TRAP) in human plasma

Shuford, C. M., Hawkridge, A. M., Burnett, J. C. J. & Muddiman, D. C., Dec 15 2010, In : Analytical Chemistry. 82, 24, p. 10179-10185 7 p.

Research output: Contribution to journalArticle

Plasma (human)
Plasmas
Proteins
Brain Natriuretic Peptide
Biomarkers
2011
60 Citations (Scopus)

A genetic variant of the atrial natriuretic peptide gene is associated with cardiometabolic protection in the general community

Cannone, V., Boerrigter, G., Cataliotti, A., Costello-Boerrigter, L. C., Olson, T. M., McKie, P., Heublein, D. M., Lahr, B. D., Bailey, K. R., Averna, M., Redfield, M. M., Rodeheffer, R. J. & Burnett, J. C. J., Aug 2 2011, In : Journal of the American College of Cardiology. 58, 6, p. 629-636 8 p.

Research output: Contribution to journalArticle

Atrial Natriuretic Factor
Alleles
Blood Pressure
Body Mass Index
Genes
3 Citations (Scopus)

Can a cardiac peptide predict mortality in human hypertension?

Cannone, V., McKie, P. & Burnett, J. C. J., Apr 2011, In : Hypertension. 57, 4, p. 670-671 2 p.

Research output: Contribution to journalArticle

Brain Natriuretic Peptide
Hypertension
Peptides
Mortality
101 Citations (Scopus)

Cardiorenal actions of TRV120027, a novel ß-arrestin-biased ligand at the angiotensin II type i receptor, in healthy and heart failure canines: A novel therapeutic strategy for acute heart failure

Boerrigter, G., Lark, M. W., Whalen, E. J., Soergel, D. G., Violin, J. D. & Burnett, J. C. J., Nov 2011, In : Circulation: Heart Failure. 4, 6, p. 770-778 9 p.

Research output: Contribution to journalArticle

Arrestin
Angiotensin Receptors
Canidae
Heart Failure
Ligands
88 Citations (Scopus)

Changes in renal function during hospitalization and soon after discharge in patients admitted for worsening heart failure in the placebo group of the EVEREST trial

Blair, J. E. A., Pang, P. S., Schrier, R. W., Metra, M., Traver, B., Cook, T., Campia, U., Ambrosy, A., Burnett, J. C. J., Grinfeld, L., Maggioni, A. P., Swedberg, K., Udelson, J. E., Zannad, F., Konstam, M. A. & Gheorghiade, M., Oct 2011, In : European Heart Journal. 32, 20, p. 2563-2572 10 p.

Research output: Contribution to journalArticle

Patient Discharge
Hospitalization
Heart Failure
Placebos
Kidney
1 Citation (Scopus)

Controlling the flood gates: Vaptans, furosemide and the quest for a renal protective diuresis

Costello-Boerrigter, L. C. & Burnett, J. C. J., Dec 2011, In : Journal of Cardiac Failure. 17, 12, p. 990-992 3 p.

Research output: Contribution to journalArticle

Benzazepines
Systolic Heart Failure
Sodium Potassium Chloride Symporter Inhibitors
Vasopressin Receptors
Diuresis
67 Citations (Scopus)

Corin is present in the normal human heart, kidney, and blood, with Pro-B-type natriuretic peptide processing in the circulation

Ichiki, T., Huntley, B. K., Heublein, D. M., Sandberg, S. M., McKie, P., Martin, F. L., Jougasaki, M. & Burnett, J. C. J., Jan 2011, In : Clinical Chemistry. 57, 1, p. 40-47 8 p.

Research output: Contribution to journalArticle

Brain Natriuretic Peptide
Blood
Kidney
Processing
Plasmas
17 Citations (Scopus)

Designer natriuretic peptides: A vision for the future of heart failure therapeutics

Zakeri, R. & Burnett, J. C. J., Aug 2011, In : Canadian Journal of Physiology and Pharmacology. 89, 8, p. 593-601 9 p.

Research output: Contribution to journalArticle

Natriuretic Peptides
Heart Failure
Brain Natriuretic Peptide
Therapeutics
Peptides
11 Citations (Scopus)

Effect of cardiac resynchronization therapy on broad neurohormone biomarkers in heart failure.

Dong, Y. X., Burnett, J. C. J., Chen, H. H., Sandberg, S., Yang, Y. Z., Zhang, Y., Chen, P. S. & Cha, Y-M., Apr 2011, In : Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing. 30, 3, p. 241-249 9 p.

Research output: Contribution to journalArticle

Cardiac Resynchronization Therapy
Neurotransmitter Agents
Heart Failure
Biomarkers
Nerve Growth Factor
31 Citations (Scopus)

Effects of tolvaptan on physician-assessed symptoms and signs in patients hospitalized with acute heart failure syndromes: Analysis from the Efficacy of Vasopressin Antagonism in Heart Failure Outcome Study with Tolvaptan (EVEREST) Trials

Pang, P. S., Gheorghiade, M., Dihu, J., Swedberg, K., Khan, S., Maggioni, A. P., Grinfeld, L., Zannad, F., Burnett, J. C. J., Ouyang, J., Udelson, J. E. & Konstam, M. A., Jun 2011, In : American Heart Journal. 161, 6, p. 1067-1072 6 p.

Research output: Contribution to journalArticle

Vasopressins
Signs and Symptoms
Heart Failure
Outcome Assessment (Health Care)
Physicians
1 Citation (Scopus)

Heart failure: Furosemide-to DOSE or not to DOSE, that is the question

Costello-Boerrigter, L. C. & Burnett, J. C. J., Jul 2011, In : Nature Reviews Cardiology. 8, 7, p. 365-366 2 p.

Research output: Contribution to journalArticle

Furosemide
Diuretics
Disease Progression
Heart Failure
Biomarkers
43 Citations (Scopus)

Impaired natriuretic and renal endocrine response to acute volume expansion in pre-clinical systolic and diastolic dysfunction

McKie, P., Schirger, J. A., Costello-Boerrigter, L. C., Benike, S. L., Harstad, L. K., Bailey, K. R., Hodge, D. O., Redfield, M. M., Simari, R. D., Burnett, J. C. J. & Chen, H. H., Nov 8 2011, In : Journal of the American College of Cardiology. 58, 20, p. 2095-2103 9 p.

Research output: Contribution to journalArticle

Natriuresis
Cyclic GMP
Brain Natriuretic Peptide
Kidney
Healthy Volunteers
58 Citations (Scopus)

Long-term cardiac pro-B-type natriuretic peptide gene delivery prevents the development of hypertensive heart disease in spontaneously hypertensive rats

Cataliotti, A., Tonne, J. M., Bellavia, D., Martin, F. L., Oehler, E. A., Harders, G. E., Campbell, J. M., Peng, K-W., Russell, S. J., Malatino, L. S., Burnett, J. C. J. & Ikeda, Y. H., Mar 29 2011, In : Circulation. 123, 12, p. 1297-1305 9 p.

Research output: Contribution to journalArticle

Brain Natriuretic Peptide
Inbred SHR Rats
Heart Diseases
Dependovirus
Blood Pressure
3 Citations (Scopus)

Natriuretic peptides: Renal protective after all?

Boerrigter, G. & Burnett, J. C. J., Aug 23 2011, In : Journal of the American College of Cardiology. 58, 9, p. 904-906 3 p.

Research output: Contribution to journalArticle

Natriuretic Peptides
Atrial Natriuretic Factor
Chronic Renal Insufficiency
Coronary Artery Bypass
Thoracic Surgery
43 Citations (Scopus)
Brain Natriuretic Peptide
Atrial Natriuretic Factor
Heart Failure
Mortality
Myocardial Infarction
55 Citations (Scopus)

Pro-B-type natriuretic peptide 1-108 circulates in the general community: Plasma determinants and detection of left ventricular dysfunction

Macheret, F., Boerrigter, G., McKie, P., Costello-Boerrigter, L., Lahr, B., Heublein, D., Sandberg, S., Ikeda, Y. H., Cataliotti, A., Bailey, K. R., Rodeheffer, R. & Burnett, J. C. J., Mar 22 2011, In : Journal of the American College of Cardiology. 57, 12, p. 1386-1395 10 p.

Research output: Contribution to journalArticle

Brain Natriuretic Peptide
Left Ventricular Dysfunction
Biomarkers
Heart Failure
Population
327 Citations (Scopus)

Progression of left ventricular diastolic dysfunction and risk of heart failure

Kane, G. M., Karon, B. L., Mahoney, D. W., Redfield, M. M., Roger, V. L., Burnett, J. C. J., Jacobsen, S. J. & Rodeheffer, R. J., Aug 24 2011, In : JAMA - Journal of the American Medical Association. 306, 8, p. 856-863 8 p.

Research output: Contribution to journalArticle

Left Ventricular Dysfunction
Heart Failure
Confidence Intervals
Population
Left Ventricular Function
39 Citations (Scopus)

Secretion of glycosylated pro-B-type natriuretic peptide from normal cardiomyocytes

Tonne, J. M., Campbell, J. M., Cataliotti, A., Ohmine, S., Thatava, T., Sakuma, T., Macheret, F., Huntley, B. K., Burnett, J. C. J. & Ikeda, Y. H., Jun 2011, In : Clinical Chemistry. 57, 6, p. 864-873 10 p.

Research output: Contribution to journalArticle

Brain Natriuretic Peptide
Cardiac Myocytes
Glycosylation
Pro-BNP1-108
Secretory Vesicles