• 37670 Citations
  • 95 Scopus h-Index
1975 …2020

Research output per year

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Research Output

2020

B-type natriuretic peptide and cardiac remodelling after myocardial infarction: A randomised trial

Hubers, S. A., Schirger, J. A., Sangaralingham, S. J., Chen, Y., Burnett, J. C., Hodge, D. & Chen, H. H., 2020, (Accepted/In press) In : Heart.

Research output: Contribution to journalArticle

Cardiorenal syndrome: Multi-organ dysfunction involving the heart, kidney and vasculature

Savira, F., Magaye, R., Liew, D., Reid, C., Kelly, D. J., Kompa, A. R., Sangaralingham, S. J., Burnett, J. C., Kaye, D. & Wang, B. H., Jul 1 2020, In : British Journal of Pharmacology. 177, 13, p. 2906-2922 17 p.

Research output: Contribution to journalReview article

2 Scopus citations

Circulating Neprilysin in Patients With Heart Failure and Preserved Ejection Fraction

Lyle, M. A., Iyer, S. R., Redfield, M. M., Reddy, Y. N. V., Felker, G. M., Cappola, T. P., Hernandez, A. F., Scott, C. G., Burnett, J. C. & Pereira, N. L., Jan 2020, In : JACC: Heart Failure. 8, 1, p. 70-80 11 p.

Research output: Contribution to journalArticle

10 Scopus citations

C-type natriuretic peptide: The heart's guardian angel

Sangaralingham, S. J., Chen, Y. & Burnett, J. C., Mar 1 2020, In : European heart journal. 41, 9, p. 1021-1023 3 p.

Research output: Contribution to journalReview article

1 Scopus citations

Long-term blood pressure lowering and cGMP-activating actions of the novel ANP analog MANP

Chen, Y., Schaefer, J. J., Iyer, S. R., Harders, G. E., Pan, S., Sangaralingham, S. J., Chen, H. H., Redfield, M. M. & Burnett, J. C., Apr 2020, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 318, 4, p. R669-R676

Research output: Contribution to journalArticle

1 Scopus citations

Natriuretic Peptides, Inflammation, and Sounding the Alarm

Ramakrishnan, V. & Burnett, J. C., Jul 1 2020, In : Circulation: Heart Failure. 13, 7, p. 145-147 3 p.

Research output: Contribution to journalReview article

Natriuretic Peptides as Inclusion Criteria in Clinical Trials: A JACC: Heart Failure Position Paper

Ibrahim, N. E., Burnett, J. C., Butler, J., Camacho, A., Felker, G. M., Fiuzat, M., O'Connor, C., Solomon, S. D., Vaduganathan, M., Zile, M. R. & Januzzi, J. L., May 2020, In : JACC: Heart Failure. 8, 5, p. 347-358 12 p.

Research output: Contribution to journalReview article

4 Scopus citations
Open Access

Rationale and design for a multicenter, randomized, double-blind, placebo-controlled, phase 2 study evaluating the safety and efficacy of the soluble guanylate cyclase stimulator praliciguat over 12 weeks in patients with heart failure with preserved ejection fraction (CAPACITY HFpEF)

Udelson, J. E., Lewis, G. D., Shah, S. J., Zile, M. R., Redfield, M. M., Burnett, J., Mittleman, R. S., Profy, A. T., Seferovic, J. P., Reasner, D. & Konstam, M. A., Apr 2020, In : American heart journal. 222, p. 183-190 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Reply: The Role of miRNAs and lncRNAs in ANP Production Downregulation in Heart Failure

Reginauld, S. H. & Burnett, J. C., Jan 2020, In : JACC: Heart Failure. 8, 1, p. 85 1 p.

Research output: Contribution to journalLetter

Open Access

Vericiguat - Another victory for targeting cyclic GMP in heart failure

Burnett, J. C., May 14 2020, In : New England Journal of Medicine. 382, 20, p. 1952-1953 2 p.

Research output: Contribution to journalEditorial

2019

Association Between Cardiac Natriuretic Peptides and Lipid Profile: a Systematic Review and Meta-Analysis

Spannella, F., Giulietti, F., Bordicchia, M., Burnett, J. C. & Sarzani, R., Dec 1 2019, In : Scientific reports. 9, 1, 19178.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Atrial natriuretic peptide: A molecular target of novel therapeutic approaches to cardio-metabolic disease

Cannone, V., Cabassi, A., Volpi, R. & Burnett, J. C., Jul 1 2019, In : International journal of molecular sciences. 20, 13, 3265.

Research output: Contribution to journalReview article

Open Access
4 Scopus citations

Atrial natriuretic peptide, heart failure and the heart as an endocrine organ

Burnett, J. C., Jan 1 2019, In : Clinical chemistry. 65, 12, p. 1602-1603 2 p.

Research output: Contribution to journalComment/debate

1 Scopus citations
7 Scopus citations

Cardiac Versus Renal Response to Volume Expansion in Preclinical Systolic Dysfunction With PDEV Inhibition and BNP

Wan, S. H., Torres-Courchoud, I., McKie, P. M., Slusser, J. P., Redfield, M. M., Burnett, J. C., Hodge, D. O. & Chen, H. H., Dec 2019, In : JACC: Basic to Translational Science. 4, 8, p. 962-972 11 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Correction: Discovery of O-glycans on atrial natriuretic peptide (ANP) that affect both its proteolytic degradation and potency at its cognate receptor (Journal of Biological Chemistry (2019) 294 (12567–12578) DOI: 10.1074/jbc.RA119.008102)

Hansen, L. H., Madsen, T. D., Goth, C. K., Clausen, H., Chen, Y., Dzoyashvili, N., Iyer, S. R., Sangaralingham, S. J., Burnett, J. C., Rehfeld, J. F., Vakhrushev, S. Y., Schjoldager, K. T. & Goetze, J. P., Nov 29 2019, In : Journal of Biological Chemistry. 294, 48, p. 18516 1 p.

Research output: Contribution to journalComment/debate

Open Access

CRRl269: A novel particulate guanylyl cyclase a receptor peptide activator for acute kidney injury

Chen, Y., Harty, G. J., Zheng, Y., Iyer, S. R., Sugihara, S., Sangaralingham, S. J., Ichiki, T., Grande, J. P., Lee, H. C., Wang, X. & Burnett, J. C., May 10 2019, In : Circulation research. 124, 10, p. 1462-1472 11 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Design, synthesis, and actions of an innovative bispecific designer peptide: NPA7

Meems, L. M. G., Andersen, I. A., Pan, S., Harty, G., Chen, Y., Zheng, Y., Harders, G. E., Ichiki, T., Heublein, D. M., Iyer, S. R., Sangaralingham, S. J., McCormick, D. J. & Burnett, J. C., Apr 1 2019, In : Hypertension. 73, 4, p. 900-909 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Differential Regulation of ANP and BNP in Acute Decompensated Heart Failure: Deficiency of ANP

Reginauld, S. H., Cannone, V., Iyer, S., Scott, C., Bailey, K., Schaefer, J., Chen, Y., Sangaralingham, S. J. & Burnett, J. C., Oct 2019, In : JACC: Heart Failure. 7, 10, p. 891-898 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Discovery of O-glycans on atrial natriuretic peptide (ANP) that affect both its proteolytic degradation and potency at its cognate receptor

Hansen, L. H., Madsen, T. D., Goth, C. K., Clausen, H., Chen, Y., Dzhoyashvili, N., Iyer, S. R., Sangaralingham, S. J., Burnett, J. C., Rehfeld, J. F., Vakhrushev, S. Y., Schjoldager, K. T. & Goetze, J. P., Aug 23 2019, In : Journal of Biological Chemistry. 294, 34, p. 12567-12578 12 p.

Research output: Contribution to journalReview article

Open Access
12 Scopus citations

Effect of Neprilysin Inhibition on Various Natriuretic Peptide Assays

Ibrahim, N. E., McCarthy, C. P., Shrestha, S., Gaggin, H. K., Mukai, R., Szymonifka, J., Apple, F. S., Burnett, J. C., Iyer, S. & Januzzi, J. L., Mar 26 2019, In : Journal of the American College of Cardiology. 73, 11, p. 1273-1284 12 p.

Research output: Contribution to journalArticle

29 Scopus citations

Effect of Testosterone on Natriuretic Peptide Levels

Bachmann, K. N., Huang, S., Lee, H., Dichtel, L. E., Gupta, D. K., Burnett, J. C., Miller, K. K., Wang, T. J. & Finkelstein, J. S., Mar 26 2019, In : Journal of the American College of Cardiology. 73, 11, p. 1288-1296 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

High doses of ANP and BNP exacerbate lipolysis in humans and the lipolytic effect of BNP is associated with cardiac triglyceride content in pigs

Bartels, E. D., Guo, S., Kousholt, B. S., Larsen, J. R., Hasenkam, J. M., Burnett, J., Nielsen, L. B., Ashina, M. & Goetze, J. P., Feb 2019, In : Peptides. 112, p. 43-47 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

Myocardial Aging, the Cardiac Atria, and BNP: What Does it All Mean?

Burnett, J. C., Ma, X. & McKie, P. M., Oct 8 2019, In : Journal of the American College of Cardiology. 74, 14, p. 1801-1803 3 p.

Research output: Contribution to journalEditorial

Natriuretic peptide based therapeutics for heart failure: Cenderitide: A novel first-in-class designer natriuretic peptide

Ichiki, T., Dzhoyashvili, N. & Burnett, J. C., Apr 15 2019, In : International Journal of Cardiology. 281, p. 166-171 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

Novel therapeutic approaches targeting the renin-angiotensin system and associated peptides in hypertension and heart failure

Arendse, L. B., Jan Danser, A. H., Poglitsch, M., Touyz, R. M., Burnett, J. C., Llorens-Cortes, C., Ehlers, M. R. & Sturrock, E. D., Oct 1 2019, In : Pharmacological Reviews. 71, 4, p. 539-570 32 p.

Research output: Contribution to journalArticle

Open Access
39 Scopus citations

NT-proBNP, race and endothelial function in the Multi-Ethnic Study of Atherosclerosis

Yang, S., Huang, S., Daniels, L. B., Yeboah, J., Lima, J. A. C., Cannone, V., Burnett, J. C., Beckman, J. A., Carr, J. J., Wang, T. J. & Gupta, D. K., Oct 1 2019, In : Heart. 105, 20, p. 1590-1596 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Soluble Neprilysin in the General Population: Clinical Determinants and Its Relationship to Cardiovascular Disease

Reddy, Y. N. V., Iyer, S. R., Scott, C. G., Rodeheffer, R. J., Bailey, K., Jenkins, G., Batzler, A., Redfield, M. M., Burnett, J. C. & Pereira, N. L., Aug 6 2019, In : Journal of the American Heart Association. 8, 15, e012943.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Enzymes

CGTP Collaborators, Dec 1 2019, In : British Journal of Pharmacology. 176, S1, p. S297-S396

Research output: Contribution to journalArticle

Open Access
150 Scopus citations

The Kidney, Bone Marrow, and Heart Connection in Acute Kidney Injury: Role of Galecin-3

Chen, Y. & Burnett, J. C., Oct 2019, In : JACC: Basic to Translational Science. 4, 6, p. 733-735 3 p.

Research output: Contribution to journalEditorial

Open Access
2018

A Human Study to Evaluate Safety, Tolerability, and Cyclic GMP Activating Properties of Cenderitide in Subjects With Stable Chronic Heart Failure

Kawakami, R., Lee, C. Y. W., Scott, C., Bailey, K. R., Schirger, J. A., Chen, H. H., Benike, S. L., Cannone, V., Martin, F. L., Sangaralingham, S. J., Ichiki, T. & Burnett, J. C., Sep 2018, In : Clinical pharmacology and therapeutics. 104, 3, p. 546-552 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Aldosterone, Hypertension, and Antihypertensive Therapy: Insights From a General Population

Cannone, V., Buglioni, A., Sangaralingham, S. J., Scott, C., Bailey, K. R., Rodeheffer, R., Redfield, M. M., Sarzani, R. & Burnett, J. C., Aug 2018, In : Mayo Clinic proceedings. 93, 8, p. 980-990 11 p.

Research output: Contribution to journalArticle

6 Scopus citations

Bioactive Signaling in Next-Generation Pharmacotherapies for Heart Failure: A Review

Oatmen, K. E., Zile, M. R., Burnett, J. C. J. & Spinale, F. G., Jan 1 2018, (Accepted/In press) In : JAMA Cardiology.

Research output: Contribution to journalArticle

3 Scopus citations

CRRL269: a novel designer and renal-enhancing pGC-A peptide activator

Chen, Y., Harty, G. J., Huntley, B. K., Iyer, S. R., Heublein, D. M., Harders, G. E., Meems, L., Pan, S., Sangaralingham, S. J., Ichiki, T. & Burnett, J. C., Mar 1 2018, In : American journal of physiology. Regulatory, integrative and comparative physiology. 314, 3, p. R407-R414

Research output: Contribution to journalArticle

9 Scopus citations
10 Scopus citations

Relaxing with c-type natriuretic peptide, the guanylyl cyclase b receptor, and pericytes

Sangaralingham, S. J. & Burnett, J. C., 2018, In : Circulation. 138, 5, p. 509-512 4 p.

Research output: Contribution to journalReview article

2 Scopus citations
2017

A favorable cardiometabolic profile is associated with the G allele of the genetic variant rs5068 in African Americans: The Multi-Ethnic Study of Atherosclerosis (MESA)

Cannone, V., Scott, C. G., Decker, P. A., Larson, N. B., Palmas, W., Taylor, K. D., Wang, T. J., Gupta, D. K., Bielinski, S. J. & Burnett, J. C., Dec 2017, In : PloS one. 12, 12, e0189858.

Research output: Contribution to journalArticle

8 Scopus citations

Atrial natriuretic peptide: Old but new therapeutic in cardiovascular diseases

Ichiki, T. & Burnett, J. C., 2017, In : Circulation Journal. 81, 7, p. 913-919 7 p.

Research output: Contribution to journalReview article

10 Scopus citations

Biochemistry, therapeutics, and biomarker implications of neprilysin in cardiorenal disease

Chen, Y. & Burnett, J. C., Jan 2017, In : Clinical chemistry. 63, 1, p. 108-115 8 p.

Research output: Contribution to journalReview article

20 Scopus citations

BLAST-AHF: Insights into biased AT1 ligands and heart failure. Beginning of the end or end of the beginning?

Sugihara, S. & Burnett, J. C., Aug 7 2017, In : European heart journal. 38, 30, p. 2374-2376 3 p.

Research output: Contribution to journalReview article

1 Scopus citations

Differences in Natriuretic Peptide Levels by Race/Ethnicity (From the Multi-Ethnic Study of Atherosclerosis)

Gupta, D. K., Daniels, L. B., Cheng, S., deFilippi, C. R., Criqui, M. H., Maisel, A. S., Lima, J. A., Bahrami, H., Greenland, P., Cushman, M., Tracy, R., Siscovick, D., Bertoni, A. G., Cannone, V., Burnett, J. C., Carr, J. J. & Wang, T. J., Sep 15 2017, In : American Journal of Cardiology. 120, 6, p. 1008-1015 8 p.

Research output: Contribution to journalArticle

24 Scopus citations

Divergent effects of a designer natriuretic peptide CD-NP in the regulation of adipose tissue and metabolism

Glöde, A., Naumann, J., Gnad, T., Cannone, V., Kilic, A., Burnett, J. C. & Pfeifer, A., Mar 1 2017, In : Molecular Metabolism. 6, 3, p. 276-287 12 p.

Research output: Contribution to journalArticle

8 Scopus citations

Early activation of deleterious molecular pathways in the kidney in experimental heart failure with atrial remodeling

Ichiki, T., Huntley, B. K., Harty, G. J., Sangaralingham, S. J. & Burnett, J. C., May 2017, In : Physiological reports. 5, 9, e13283.

Research output: Contribution to journalArticle

4 Scopus citations

Experimental cardiac radiation exposure induces ventricular diastolic dysfunction with preserved ejection fraction

Saiki, H., Moulay, G., Guenzel, A. J., Liu, W., Decklever, T. D., Classic, K. L., Pham, L., Chen, H. H., Burnett, J. C., Russell, S. J. & Redfield, M. M., Aug 11 2017, In : American Journal of Physiology - Heart and Circulatory Physiology. 313, 2, p. H392-H407

Research output: Contribution to journalArticle

14 Scopus citations

Neurohumoral modulation during waon therapy in chronic heart failure: Subanalysis of Waon-CHF study

WAON-CHF Study Investigators, 2017, In : Circulation Journal. 81, 5, p. 700-716 17 p.

Research output: Contribution to journalArticle

6 Scopus citations
2016

Arterial remodeling in B-type natriuretic peptide knock-out females

Holditch, S. J., Schreiber, C. A., Burnett, J. C. & Ikeda, Y., May 10 2016, In : Scientific reports. 6, 25623.

Research output: Contribution to journalArticle

5 Scopus citations

Biomarker-based risk prediction in the community

Abou Ezzeddine, O., McKie, P., Scott, C. G., Rodeheffer, R. J., Chen, H. H., Michael Felker, G., Jaffe, A. S., Burnett, J. C. J. & Redfield, M. M., Nov 1 2016, In : European Journal of Heart Failure. 18, 11, p. 1342-1350 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Cardiorenal fibrosis and dysfunction in aging: Imbalance in mediators and regulators of collagen

Sangaralingham, S. J., Wang, B. H., Huang, L., Kumfu, S., Ichiki, T., Krum, H. & Burnett, J. C., Feb 1 2016, In : Peptides. 76, p. 108-114 7 p.

Research output: Contribution to journalArticle

22 Scopus citations
14 Scopus citations