Research output per year
Research output per year
- 1 - 50 out of 603 results
Search results
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2023
Natriuretic peptide pathways in heart failure: further therapeutic possibilities
Sangaralingham, S. J., Kuhn, M., Cannone, V., Chen, H. H. & Burnett, J. C., Feb 3 2023, In: Cardiovascular research. 118, 18, p. 3416-3433 18 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2022
Cardiorenal Effects of Long-Term Phosphodiesterase V Inhibition in Pre– Heart Failure
Hubers, S. A., Wan, S. H., Adel, F. W., Benike, S. L., Burnett, J. C., Scott, C. & Chen, H. H., Jan 18 2022, In: Journal of the American Heart Association. 11, 2, e022126.Research output: Contribution to journal › Article › peer-review
Open Access -
Cyclic GMP modulating drugs in cardiovascular diseases: mechanism-based network pharmacology
Petraina, A., Nogales, C., Krahn, T., Mucke, H., Lüscher, T. F., Fischmeister, R., Kass, D. A., Burnett, J. C., Hobbs, A. J. & Schmidt, H. H. H. W., May 1 2022, In: Cardiovascular research. 118, 9, p. 2085-2102 18 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
MANP (M-Atrial Natriuretic Peptide) Reduces Blood Pressure and Furosemide-Induced Increase in Aldosterone in Hypertension
Dzhoyashvili, N. A., Iyer, S. R., Chen, H. H. & Burnett, J. C., Apr 1 2022, In: Hypertension. 79, 4, p. 750-760 11 p.Research output: Contribution to journal › Article › peer-review
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MANP Activation of the cGMP Inhibits Aldosterone Via PDE2 and CYP11B2 in H295R Cells and in Mice
Chen, Y., Iyer, S. R., Nikolaev, V. O., Naro, F., Pellegrini, M., Cardarelli, S., Ma, X., Lee, H. C. & Burnett, J. C., Aug 1 2022, In: Hypertension. 79, 8, p. 1702-1712 11 p.Research output: Contribution to journal › Article › peer-review
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Natriuretic Peptides and Blood Pressure Homeostasis: Implications for MANP, a Novel Guanylyl Cyclase a Receptor Activator for Hypertension
Cannone, V. & Burnett, J. C., Feb 11 2022, In: Frontiers in Physiology. 12, 815796.Research output: Contribution to journal › Article › peer-review
Open Access -
Proteomic Biomarkers of Sacubitril/Valsartan Treatment Response in Heart Failure With Preserved Ejection Fraction: Molecular Insights Into Sex Differences
Nguyen, T. T. L., Wang, M., Liu, D., Iyer, S., Gonzalez Bonilla, H. M., Acker, N., Murthy, V., Shrivastava, S., Desai, V., Burnett, J. C., Redfield, M., Bailey, K. R., Weinshilboum, R. M. & Pereira, N. L., Sep 1 2022, In: Circulation: Heart Failure. 15, 9, p. E009629Research output: Contribution to journal › Article › peer-review
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Purification, characterization, and preliminary serial crystallography diffraction advances structure determination of full-length human particulate guanylyl cyclase A receptor
Zhang, S., Hansen, D. T., Martin-Garcia, J. M., Zook, J. D., Pan, S., Craciunescu, F. M., Burnett, J. C. & Fromme, P., Dec 2022, In: Scientific reports. 12, 1, 11824.Research output: Contribution to journal › Article › peer-review
Open Access -
2021
Angiotensin (1-12) in Humans With Normal Blood Pressure and Primary Hypertension
Ferrario, C. M., Iyer, S. R., Burnett, J. C., Ahmad, S., Wright, K. N., Voncannon, J. L., Saha, A. & Groban, L., Mar 3 2021, In: Hypertension. 77, 3, p. 882-890 9 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Atrial Natriuretic Peptide and Treatment With Sacubitril/Valsartan in Heart Failure With Reduced Ejection Fraction
Murphy, S. P., Prescott, M. F., Camacho, A., Iyer, S. R., Maisel, A. S., Felker, G. M., Butler, J., Piña, I. L., Ibrahim, N. E., Abbas, C., Burnett, J. C., Solomon, S. D. & Januzzi, J. L., Feb 2021, In: JACC: Heart Failure. 9, 2, p. 127-136 10 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
B-type natriuretic peptide and cardiac remodelling after myocardial infarction: A randomised trial
Hubers, S. A., Schirger, J. A., Sangaralingham, S. J., Chen, Y., Burnett, J. C., Hodge, D. & Chen, H. H., Mar 1 2021, In: Heart. 107, 5, p. 396-402 7 p.Research output: Contribution to journal › Article › peer-review
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Discovery of small molecule guanylyl cyclase A receptor positive allosteric modulators
Sangaralingham, S. J., Whig, K., Peddibhotla, S., Kirby, R. J., Sessions, H. E., Maloney, P. R., Hershberger, P. M., Mose-Yates, H., Hood, B. L., Vasile, S., Pan, S., Zheng, Y., Malany, S. & Burnett, J. C., Dec 28 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 52, e2109386118.Research output: Contribution to journal › Article › peer-review
Open Access -
Effects of phosphodiesterase V inhibition alone and in combination with BNP on cardiovascular and renal response to volume load in human preclinical diastolic dysfunction
Wan, S. H., McKie, P. M., Slusser, J. P., Burnett, J. C., Hodge, D. O. & Chen, H. H., Aug 2021, In: Physiological reports. 9, 16, e14974.Research output: Contribution to journal › Article › peer-review
Open Access -
First-in-Human Study of MANP: A Novel ANP (Atrial Natriuretic Peptide) Analog in Human Hypertension
Chen, H. H., Wan, S. H., Iyer, S. R., Cannone, V., Sangaralingham, S. J., Nuetel, J. & Burnett, J. C., Dec 1 2021, In: Hypertension. 78, 6, p. 1859-1867 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Prognostic Value of Urinary and Plasma C-Type Natriuretic Peptide in Acute Decompensated Heart Failure
Ma, X., Chen, Y., Reginauld, S. H., Scott, C. G., Iyer, S. R., Schaefer, J. J., Ichiki, T., Chen, H. H., Rule, A. D., Burnett, J. C. & Sangaralingham, S. J., Sep 2021, In: JACC: Heart Failure. 9, 9, p. 613-623 11 p.Research output: Contribution to journal › Article › peer-review
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STOP-HF Trial: Higher Endogenous BNP and Cardiovascular Protection in Subjects at Risk for Heart Failure
Cannone, V., Ledwidge, M., Watson, C., McKie, P. M., Burnett, J. C. & McDonald, K., Jun 2021, In: JACC: Basic to Translational Science. 6, 6, p. 497-504 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Catalytic receptors
Alexander, S. P. H., Fabbro, D., Kelly, E., Mathie, A., Peters, J. A., Veale, E. L., Armstrong, J. F., Faccenda, E., Harding, S. D., Pawson, A. J., Southan, C., Davies, J. A., Beuve, A., Brouckaert, P., Bryant, C., Burnett, J. C., Farndale, R. W., Friebe, A., Garthwaite, J., Hobbs, A. J., & 9 others, Oct 2021, In: British Journal of Pharmacology. 178, S1, p. S264-S312Research output: Contribution to journal › Article › peer-review
Open Access -
2020
Cardiorenal syndrome: Multi-organ dysfunction involving the heart, kidney and vasculature
Savira, F., Magaye, R., Liew, D., Reid, C., Kelly, D. J., Kompa, A. R., Sangaralingham, S. J., Burnett, J. C., Kaye, D. & Wang, B. H., Jul 1 2020, In: British Journal of Pharmacology. 177, 13, p. 2906-2922 17 p.Research output: Contribution to journal › Review article › peer-review
Open Access5 Scopus citations -
Circulating Neprilysin in Patients With Heart Failure and Preserved Ejection Fraction
Lyle, M. A., Iyer, S. R., Redfield, M. M., Reddy, Y. N. V., Felker, G. M., Cappola, T. P., Hernandez, A. F., Scott, C. G., Burnett, J. C. & Pereira, N. L., Jan 2020, In: JACC: Heart Failure. 8, 1, p. 70-80 11 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
C-type natriuretic peptide: The heart's guardian angel
Sangaralingham, S. J., Chen, Y. & Burnett, J. C., Mar 1 2020, In: European heart journal. 41, 9, p. 1021-1023 3 p.Research output: Contribution to journal › Review article › peer-review
1 Scopus citations -
Effect of Praliciguat on Peak Rate of Oxygen Consumption in Patients with Heart Failure with Preserved Ejection Fraction: The CAPACITY HFpEF Randomized Clinical Trial
Udelson, J. E., Lewis, G. D., Shah, S. J., Zile, M. R., Redfield, M. M., Burnett, J., Parker, J., Seferovic, J. P., Wilson, P., Mittleman, R. S., Profy, A. T. & Konstam, M. A., Oct 20 2020, In: JAMA - Journal of the American Medical Association. 324, 15, p. 1522-1531 10 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Long-term blood pressure lowering and cGMP-activating actions of the novel ANP analog MANP
Chen, Y., Schaefer, J. J., Iyer, S. R., Harders, G. E., Pan, S., Sangaralingham, S. J., Chen, H. H., Redfield, M. M. & Burnett, J. C., Apr 2020, In: American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 318, 4, p. R669-R676Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Natriuretic Peptides, Inflammation, and Sounding the Alarm
Ramakrishnan, V. & Burnett, J. C., Jul 1 2020, In: Circulation: Heart Failure. 13, 7, p. 145-147 3 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
Natriuretic Peptides as Inclusion Criteria in Clinical Trials: A JACC: Heart Failure Position Paper
Ibrahim, N. E., Burnett, J. C., Butler, J., Camacho, A., Felker, G. M., Fiuzat, M., O'Connor, C., Solomon, S. D., Vaduganathan, M., Zile, M. R. & Januzzi, J. L., May 2020, In: JACC: Heart Failure. 8, 5, p. 347-358 12 p.Research output: Contribution to journal › Review article › peer-review
Open Access18 Scopus citations -
Neprilysin in HFrEF: Differential Regulation of Tissue Versus Circulating Neprilysin
Chen, H. H. & Burnett, J. C., Jul 2020, In: JACC: Basic to Translational Science. 5, 7, p. 727-729 3 p.Research output: Contribution to journal › Editorial › peer-review
Open Access -
Rationale and design for a multicenter, randomized, double-blind, placebo-controlled, phase 2 study evaluating the safety and efficacy of the soluble guanylate cyclase stimulator praliciguat over 12 weeks in patients with heart failure with preserved ejection fraction (CAPACITY HFpEF)
Udelson, J. E., Lewis, G. D., Shah, S. J., Zile, M. R., Redfield, M. M., Burnett, J., Mittleman, R. S., Profy, A. T., Seferovic, J. P., Reasner, D. & Konstam, M. A., Apr 2020, In: American heart journal. 222, p. 183-190 8 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Reply: The Role of miRNAs and lncRNAs in ANP Production Downregulation in Heart Failure
Reginauld, S. H. & Burnett, J. C., Jan 2020, In: JACC: Heart Failure. 8, 1, p. 85 1 p.Research output: Contribution to journal › Letter › peer-review
Open Access -
Vericiguat - Another victory for targeting cyclic GMP in heart failure
Burnett, J. C., May 14 2020, In: New England Journal of Medicine. 382, 20, p. 1952-1953 2 p.Research output: Contribution to journal › Editorial › peer-review
2 Scopus citations -
2019
Association Between Cardiac Natriuretic Peptides and Lipid Profile: a Systematic Review and Meta-Analysis
Spannella, F., Giulietti, F., Bordicchia, M., Burnett, J. C. & Sarzani, R., Dec 1 2019, In: Scientific reports. 9, 1, 19178.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Atrial natriuretic peptide: A molecular target of novel therapeutic approaches to cardio-metabolic disease
Cannone, V., Cabassi, A., Volpi, R. & Burnett, J. C., Jul 1 2019, In: International journal of molecular sciences. 20, 13, 3265.Research output: Contribution to journal › Review article › peer-review
Open Access11 Scopus citations -
Atrial natriuretic peptide, heart failure and the heart as an endocrine organ
Burnett, J. C., 2019, In: Clinical chemistry. 65, 12, p. 1602-1603 2 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access1 Scopus citations -
C53: A novel particulate guanylyl cyclase B receptor activator that has sustained activity in vivo with anti-fibrotic actions in human cardiac and renal fibroblasts
Chen, Y., Zheng, Y., Iyer, S. R., Harders, G. E., Pan, S., Chen, H. H., Ichiki, T., Burnett, J. C. & Sangaralingham, S. J., May 2019, In: Journal of Molecular and Cellular Cardiology. 130, p. 140-150 11 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Cardiac Versus Renal Response to Volume Expansion in Preclinical Systolic Dysfunction With PDEV Inhibition and BNP
Wan, S. H., Torres-Courchoud, I., McKie, P. M., Slusser, J. P., Redfield, M. M., Burnett, J. C., Hodge, D. O. & Chen, H. H., Dec 2019, In: JACC: Basic to Translational Science. 4, 8, p. 962-972 11 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Correction: Discovery of O-glycans on atrial natriuretic peptide (ANP) that affect both its proteolytic degradation and potency at its cognate receptor (Journal of Biological Chemistry (2019) 294 (12567–12578) DOI: 10.1074/jbc.RA119.008102)
Hansen, L. H., Madsen, T. D., Goth, C. K., Clausen, H., Chen, Y., Dzoyashvili, N., Iyer, S. R., Sangaralingham, S. J., Burnett, J. C., Rehfeld, J. F., Vakhrushev, S. Y., Schjoldager, K. T. & Goetze, J. P., Nov 29 2019, In: Journal of Biological Chemistry. 294, 48, p. 18516 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access1 Scopus citations -
CRRl269: A novel particulate guanylyl cyclase a receptor peptide activator for acute kidney injury
Chen, Y., Harty, G. J., Zheng, Y., Iyer, S. R., Sugihara, S., Sangaralingham, S. J., Ichiki, T., Grande, J. P., Lee, H. C., Wang, X. & Burnett, J. C., May 10 2019, In: Circulation research. 124, 10, p. 1462-1472 11 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Design, synthesis, and actions of an innovative bispecific designer peptide: NPA7
Meems, L. M. G., Andersen, I. A., Pan, S., Harty, G., Chen, Y., Zheng, Y., Harders, G. E., Ichiki, T., Heublein, D. M., Iyer, S. R., Sangaralingham, S. J., McCormick, D. J. & Burnett, J. C., Apr 1 2019, In: Hypertension. 73, 4, p. 900-909 10 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Differential Regulation of ANP and BNP in Acute Decompensated Heart Failure: Deficiency of ANP
Reginauld, S. H., Cannone, V., Iyer, S., Scott, C., Bailey, K., Schaefer, J., Chen, Y., Sangaralingham, S. J. & Burnett, J. C., Oct 2019, In: JACC: Heart Failure. 7, 10, p. 891-898 8 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Discovery of O-glycans on atrial natriuretic peptide (ANP) that affect both its proteolytic degradation and potency at its cognate receptor
Hansen, L. H., Madsen, T. D., Goth, C. K., Clausen, H., Chen, Y., Dzhoyashvili, N., Iyer, S. R., Sangaralingham, S. J., Burnett, J. C., Rehfeld, J. F., Vakhrushev, S. Y., Schjoldager, K. T. & Goetze, J. P., Aug 23 2019, In: Journal of Biological Chemistry. 294, 34, p. 12567-12578 12 p.Research output: Contribution to journal › Review article › peer-review
Open Access17 Scopus citations -
Effect of Neprilysin Inhibition on Various Natriuretic Peptide Assays
Ibrahim, N. E., McCarthy, C. P., Shrestha, S., Gaggin, H. K., Mukai, R., Szymonifka, J., Apple, F. S., Burnett, J. C., Iyer, S. & Januzzi, J. L., Mar 26 2019, In: Journal of the American College of Cardiology. 73, 11, p. 1273-1284 12 p.Research output: Contribution to journal › Article › peer-review
41 Scopus citations -
Effect of Testosterone on Natriuretic Peptide Levels
Bachmann, K. N., Huang, S., Lee, H., Dichtel, L. E., Gupta, D. K., Burnett, J. C., Miller, K. K., Wang, T. J. & Finkelstein, J. S., Mar 26 2019, In: Journal of the American College of Cardiology. 73, 11, p. 1288-1296 9 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
High doses of ANP and BNP exacerbate lipolysis in humans and the lipolytic effect of BNP is associated with cardiac triglyceride content in pigs
Bartels, E. D., Guo, S., Kousholt, B. S., Larsen, J. R., Hasenkam, J. M., Burnett, J., Nielsen, L. B., Ashina, M. & Goetze, J. P., Feb 2019, In: Peptides. 112, p. 43-47 5 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Myocardial Aging, the Cardiac Atria, and BNP: What Does it All Mean?
Burnett, J. C., Ma, X. & McKie, P. M., Oct 8 2019, In: Journal of the American College of Cardiology. 74, 14, p. 1801-1803 3 p.Research output: Contribution to journal › Editorial › peer-review
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Natriuretic peptide based therapeutics for heart failure: Cenderitide: A novel first-in-class designer natriuretic peptide
Ichiki, T., Dzhoyashvili, N. & Burnett, J. C., Apr 15 2019, In: International Journal of Cardiology. 281, p. 166-171 6 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Novel therapeutic approaches targeting the renin-angiotensin system and associated peptides in hypertension and heart failure
Arendse, L. B., Jan Danser, A. H., Poglitsch, M., Touyz, R. M., Burnett, J. C., Llorens-Cortes, C., Ehlers, M. R. & Sturrock, E. D., Oct 1 2019, In: Pharmacological Reviews. 71, 4, p. 539-570 32 p.Research output: Contribution to journal › Article › peer-review
Open Access98 Scopus citations -
NT-proBNP, race and endothelial function in the Multi-Ethnic Study of Atherosclerosis
Yang, S., Huang, S., Daniels, L. B., Yeboah, J., Lima, J. A. C., Cannone, V., Burnett, J. C., Beckman, J. A., Carr, J. J., Wang, T. J. & Gupta, D. K., Oct 1 2019, In: Heart. 105, 20, p. 1590-1596 7 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Soluble Neprilysin in the General Population: Clinical Determinants and Its Relationship to Cardiovascular Disease
Reddy, Y. N. V., Iyer, S. R., Scott, C. G., Rodeheffer, R. J., Bailey, K., Jenkins, G., Batzler, A., Redfield, M. M., Burnett, J. C. & Pereira, N. L., Aug 6 2019, In: Journal of the American Heart Association. 8, 15, e012943.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Enzymes
CGTP Collaborators, Dec 1 2019, In: British Journal of Pharmacology. 176, S1, p. S297-S396Research output: Contribution to journal › Article › peer-review
Open Access331 Scopus citations -
The Kidney, Bone Marrow, and Heart Connection in Acute Kidney Injury: Role of Galecin-3
Chen, Y. & Burnett, J. C., Oct 2019, In: JACC: Basic to Translational Science. 4, 6, p. 733-735 3 p.Research output: Contribution to journal › Editorial › peer-review
Open Access -
2018
A Human Study to Evaluate Safety, Tolerability, and Cyclic GMP Activating Properties of Cenderitide in Subjects With Stable Chronic Heart Failure
Kawakami, R., Lee, C. Y. W., Scott, C., Bailey, K. R., Schirger, J. A., Chen, H. H., Benike, S. L., Cannone, V., Martin, F. L., Sangaralingham, S. J., Ichiki, T. & Burnett, J. C., Sep 2018, In: Clinical pharmacology and therapeutics. 104, 3, p. 546-552 7 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Aldosterone, Hypertension, and Antihypertensive Therapy: Insights From a General Population
Cannone, V., Buglioni, A., Sangaralingham, S. J., Scott, C., Bailey, K. R., Rodeheffer, R., Redfield, M. M., Sarzani, R. & Burnett, J. C., Aug 2018, In: Mayo Clinic proceedings. 93, 8, p. 980-990 11 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations