• 2886 Citations
  • 28 Scopus h-Index
20012020
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Research Output 2001 2020

  • 2886 Citations
  • 28 Scopus h-Index
  • 132 Article
2020

Decreased core symptoms of mania and utilization of lithium/mood stabilizing anticonvulsants in U.S. bipolar I patients of African vs European ancestry

Akinhanmi, M., El-Amin, S., Balls-Berry, J., Vallender, E. J., Ladner, M., Geske, J., Coombes, B., Biernacka, J. M., Kelsoe, J. & Frye, M. A., Jan 1 2020, In : Journal of Affective Disorders. 260, p. 361-365 5 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Lithium
Anticonvulsants
Hallucinations
Interviews
2019

Alcohol Craving Predicts Relapse After Residential Addiction Treatment

Stohs, M. E., Schneekloth, T. D., Geske, J. R., Biernacka, J. M. & Karpyak, V. M., Mar 1 2019, In : Alcohol and alcoholism (Oxford, Oxfordshire). 54, 2, p. 167-172 6 p.

Research output: Contribution to journalArticle

Residential Treatment
Alcohols
Recurrence
Therapeutics
Craving

Association of Cytomegalovirus and Toxoplasma gondii Antibody Titers with Bipolar Disorder

Frye, M. A., Coombes, B. J., McElroy, S. L., Jones-Brando, L., Bond, D. J., Veldic, M. D., Romo-Nava, F., Bobo, W. V., Singh, B., Colby, C., Skime, M. K., Biernacka, J. M. & Yolken, R., Jan 1 2019, (Accepted/In press) In : JAMA Psychiatry.

Research output: Contribution to journalArticle

Toxoplasma
Cytomegalovirus
Bipolar Disorder
Antibodies
Psychotic Disorders
1 Citation (Scopus)

Associations of catechol-O-methyltransferase (rs4680) single nucleotide polymorphisms with opioid use and dose among adults with chronic pain

Hooten, W. M., Biernacka, J. M., OʼBrien, T. G., Cunningham, J. M. & Black, J. L., Jan 1 2019, In : Pain. 160, 1, p. 263-268 6 p.

Research output: Contribution to journalArticle

Catechol O-Methyltransferase
Chronic Pain
Opioid Analgesics
Single Nucleotide Polymorphism
Genotype

Clinical phenotype and genetic risk factors for bipolar disorder with binge eating: an update

Cuellar-Barboza, A. B., Winham, S. J., Biernacka, J. M., Frye, M. A. & McElroy, S. L., Sep 1 2019, In : Expert review of neurotherapeutics. 19, 9, p. 867-879 13 p.

Research output: Contribution to journalArticle

Bulimia
Bipolar Disorder
Phenotype
Psychiatry
Binge-Eating Disorder

Cytochrome P450 2C19 poor metabolizer phenotype in treatment resistant depression: Treatment and diagnostic implications

Veldic, M. D., Ahmed, A. T., Blacker, C. J., Geske, J. R., Biernacka, J. M., Borreggine, K. L., Moore, K. M., Prieto, M. L., Vande Voort, J., Croarkin, P. E., Hoberg, A. A., Kung, S., Alarcon, R. D., Keeth, N., Singh, B., Bobo, W. V. & Frye, M. A., Jan 1 2019, In : Frontiers in Pharmacology. 10, FEB, 83.

Research output: Contribution to journalArticle

Open Access
Treatment-Resistant Depressive Disorder
Cytochrome P-450 Enzyme System
Phenotype
Bipolar Disorder
Major Depressive Disorder

Factor analysis of the eating disorder diagnostic scale in individuals with bipolar disorder

Crow, S., Blom, T. J., Sim, L., Cuellar-Barboza, A. B., Biernacka, J. M., Frye, M. A. & McElroy, S. L., Apr 1 2019, In : Eating Behaviors. 33, p. 30-33 4 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Statistical Factor Analysis
Bulimia
Feeding Behavior
Psychopathology
1 Citation (Scopus)

Genetic variant in SLC1A2 is associated with elevated anterior cingulate cortex glutamate and lifetime history of rapid cycling

Veldic, M. D., Millischer, V., Port, J. D., Ho, A. M. C., Jia, Y. F., Geske, J. R., Biernacka, J. M., Backlund, L., McElroy, S. L., Bond, D. J., Villaescusa, J. C., Skime, M., Choi, D. S., Lavebratt, C., Schalling, M. & Frye, M. A., Dec 1 2019, In : Translational psychiatry. 9, 1, 149.

Research output: Contribution to journalArticle

Open Access
Gyrus Cinguli
Glutamic Acid
Alleles
Single Nucleotide Polymorphism
Mood Disorders
5 Citations (Scopus)

Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD

Pottier, C., Ren, Y., Perkerson, R. B., Baker, M., Jenkins, G. D., Van Blitterswijk, M., DeJesus-Hernandez, M., van Rooij, J. G. J., Murray, M. E., Christopher, E., McDonnell, S. K., Fogarty, Z., Batzler, A., Tian, S., Vicente, C. T., Matchett, B., Karydas, A. M., Hsiung, G. Y. R., Seelaar, H., Mol, M. O. & 85 others, Finger, E. C., Graff, C., Öijerstedt, L., Neumann, M., Heutink, P., Synofzik, M., Wilke, C., Prudlo, J., Rizzu, P., Simon-Sanchez, J., Edbauer, D., Roeber, S., Diehl-Schmid, J., Evers, B. M., King, A., Mesulam, M. M., Weintraub, S., Geula, C., Bieniek, K. F., Petrucelli, L., Ahern, G. L., Reiman, E. M., Woodruff, B. K., Caselli, R. J., Huey, E. D., Farlow, M. R., Grafman, J., Mead, S., Grinberg, L. T., Spina, S., Grossman, M., Irwin, D. J., Lee, E. B., Suh, E. R., Snowden, J., Mann, D., Taner, N., Uitti, R. J., Wszolek, Z. K., Josephs, K. A., Parisi, J. E., Knopman, D. S., Petersen, R. C., Hodges, J. R., Piguet, O., Geier, E. G., Yokoyama, J. S., Rissman, R. A., Rogaeva, E., Keith, J., Zinman, L., Tartaglia, M. C., Cairns, N. J., Cruchaga, C., Ghetti, B., Kofler, J., Lopez, O. L., Beach, T. G., Arzberger, T., Herms, J., Honig, L. S., Vonsattel, J. P., Halliday, G. M., Kwok, J. B., White, C. L., Gearing, M., Glass, J., Rollinson, S., Pickering-Brown, S., Rohrer, J. D., Trojanowski, J. Q., Van Deerlin, V., Bigio, E. H., Troakes, C., Al-Sarraj, S., Asmann, Y., Miller, B. L., Graff Radford, N. R., Boeve, B. F., Seeley, W. W., Mackenzie, I. R. A., van Swieten, J. C., Dickson, D. W., Biernacka, J. M. & Rademakers, R. V., Jan 1 2019, In : Acta neuropathologica.

Research output: Contribution to journalArticle

Frontotemporal Lobar Degeneration
Frontotemporal Dementia
Genome
Genes
Mutation
20 Citations (Scopus)

Genome-wide association study identifies 30 loci associated with bipolar disorder

eQTLGen Consortium, BIOS Consortium & the Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, May 1 2019, In : Nature Genetics. 51, 5, p. 793-803 11 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Bipolar Disorder
Genome
Neurotransmitter Transport Proteins
Endocannabinoids
3 Citations (Scopus)

Investigating polygenic burden in age at disease onset in bipolar disorder: Findings from an international multicentric study

Kalman, J. L., Papiol, S., Forstner, A. J., Heilbronner, U., Degenhardt, F., Strohmaier, J., Adli, M., Adorjan, K., Akula, N., Alda, M., Anderson-Schmidt, H., Andlauer, T. F. M., Anghelescu, I. G., Ardau, R., Arias, B., Arolt, V., Aubry, J. M., Backlund, L., Bartholdi, K., Bauer, M. & 123 others, Baune, B. T., Becker, T., Bellivier, F., Benabarre, A., Bengesser, S., Bhattacharjee, A. K., Biernacka, J. M., Birner, A., Brichant-Petitjean, C., Budde, M., Cervantes, P., Chillotti, C., Cichon, S., Clark, S. R., Colom, F., Comes, A. L., Cruceanu, C., Czerski, P. M., Dannlowski, U., Dayer, A., Del Zompo, M., DePaulo, J. R., Dietrich, D. E., Étain, B., Ethofer, T., Falkai, P., Fallgatter, A., Figge, C., Flatau, L., Folkerts, H., Frisen, L., Frye, M. A., Fullerton, J. M., Gade, K., Gard, S., Garnham, J. S., Goes, F. S., Grigoroiu-Serbanescu, M., Gryaznova, A., Hake, M., Hauser, J., Herms, S., Hoffmann, P., Hou, L., Jäger, M., Jamain, S., Jiménez, E., Juckel, G., Kahn, J. P., Kassem, L., Kelsoe, J., Kittel-Schneider, S., Kliwicki, S., Klohn-Sagatholislam, F., Koller, M., König, B., Konrad, C., Lackner, N., Laje, G., Landén, M., Lang, F. U., Lavebratt, C., Leboyer, M., Leckband, S. G., Maj, M., Manchia, M., Martinsson, L., McCarthy, M. J., McElroy, S. L., McMahon, F. J., Mitchell, P. B., Mitjans, M., Mondimore, F. M., Monteleone, P., Nieratschker, V., Nievergelt, C. M., Novák, T., Ösby, U., Pfennig, A., Potash, J. B., Reich-Erkelenz, D., Reif, A., Reimer, J., Reininghaus, E., Reitt, M., Ripke, S., Rouleau, G. A., Rybakowski, J. K., Schalling, M., Scherk, H., Schmauß, M., Schofield, P. R., Schubert, K. O., Schulte, E. C., Schulz, S., Senner, F., Severino, G., Shekhtman, T., Shilling, P. D., Simhandl, C., Slaney, C. M., Spitzer, C., Squassina, A., Stamm, T., Stegmaier, S., Stierl, S., Stopkova, P., Thiel, A., Tighe, S. K., Tortorella, A., Turecki, G., Vieta, E., Veeh, J., von Hagen, M., Wigand, M. E., Wiltfang, J., Witt, S., Wright, A., Zandi, P. P., Zimmermann, J., Nöthen, M., Rietschel, M. & Schulze, T. G., Feb 1 2019, In : Bipolar disorders. 21, 1, p. 68-75 8 p.

Research output: Contribution to journalArticle

Open Access
Bipolar Disorder
Age of Onset
Schizophrenia
Public Opinion
Genomics

Multivariate generalized linear model for genetic pleiotropy

Schaid, D. J., Tong, X., Batzler, A., Sinnwell, J. P., Qing, J. & Biernacka, J. M., Jan 1 2019, In : Biostatistics (Oxford, England). 20, 1, p. 111-128 18 p.

Research output: Contribution to journalArticle

Generalized Linear Model
Null hypothesis
Null
Gene
Testing
2 Citations (Scopus)

Pharmacogenomics-Driven Prediction of Antidepressant Treatment Outcomes: A Machine-Learning Approach With Multi-trial Replication

Athreya, A. P., Neavin, D., Carrillo-Roa, T., Skime, M., Biernacka, J. M., Frye, M. A., Rush, A. J., Wang, L., Binder, E. B., Iyer, R. K., Weinshilboum, R. M. & Bobo, W. V., Jan 1 2019, In : Clinical pharmacology and therapeutics.

Research output: Contribution to journalArticle

Pharmacogenetics
Serotonin Uptake Inhibitors
Antidepressive Agents
Major Depressive Disorder
Citalopram
3 Citations (Scopus)
Citalopram
Major Depressive Disorder
Cytochrome P-450 CYP2D6
Treatment Failure
Pharmacokinetics

Sex-specific association of depressive disorder and transient emotional states with alcohol consumption in male and female alcoholics

Karpyak, V. M., Geske, J. R., Hall-Flavin, D. K., Loukianova, L. L., Schneekloth, T. D., Skime, M. K., Seppala, M., Dawson, G., Frye, M. A., Choi, D. S. & Biernacka, J. M., Mar 1 2019, In : Drug and Alcohol Dependence. 196, p. 31-39 9 p.

Research output: Contribution to journalArticle

Alcoholics
Depressive Disorder
Alcohol Drinking
Alcohols
Major Depressive Disorder
1 Citation (Scopus)

Sex-specific effects of gain-of-function P2RX7 variation on bipolar disorder

Winham, S. J., Bobo, W. V., Liu, J., Coombes, B., Backlund, L., Frye, M. A., Biernacka, J. M., Schalling, M. & Lavebratt, C., Feb 15 2019, In : Journal of Affective Disorders. 245, p. 597-601 5 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Sex Characteristics
Periodicity
Mood Disorders
Sample Size
2 Citations (Scopus)

The association of obesity and coronary artery disease genes with response to SSRIs treatment in major depression

Amare, A. T., Schubert, K. O., Tekola-Ayele, F., Hsu, Y. H., Sangkuhl, K., Jenkins, G., Whaley, R. M., Barman, P., Batzler, A., Altman, R. B., Arolt, V., Brockmöller, J., Chen, C. H., Domschke, K., Hall-Flavin, D. K., Hong, C. J., Illi, A., Ji, Y., Kampman, O., Kinoshita, T. & 17 others, Leinonen, E., Liou, Y. J., Mushiroda, T., Nonen, S., Skime, M. K., Wang, L. M., Kato, M., Liu, Y. L., Praphanphoj, V., Stingl, J. C., Bobo, W. V., Tsai, S. J., Kubo, M., Klein, T. E., Weinshilboum, R. M., Biernacka, J. M. & Baune, B. T., Jan 1 2019, (Accepted/In press) In : Journal of Neural Transmission.

Research output: Contribution to journalArticle

Serotonin Uptake Inhibitors
Coronary Artery Disease
Obesity
Depression
Genes
2018
2 Citations (Scopus)

Analysis of the influence of microRNAs in lithium response in bipolar disorder

Reinbold, C. S., Forstner, A. J., Hecker, J., Fullerton, J. M., Hoffmann, P., Hou, L., Heilbronner, U., Degenhardt, F., Adli, M., Akiyama, K., Akula, N., Ardau, R., Arias, B., Backlund, L., Benabarre, A., Bengesser, S., Bhattacharjee, A. K., Biernacka, J. M., Birner, A., Marie-Claire, C. & 101 others, Cervantes, P., Chen, G. B., Chen, H. C., Chillotti, C., Clark, S. R., Colom, F., Cousins, D. A., Cruceanu, C., Czerski, P. M., Dayer, A., Étain, B., Falkai, P., Frisén, L., Gard, S., Garnham, J. S., Goes, F. S., Grof, P., Gruber, O., Hashimoto, R., Hauser, J., Herms, S., Jamain, S., Jiménez, E., Kahn, J. P., Kassem, L., Kittel-Schneider, S., Kliwicki, S., König, B., Kusumi, I., Lackner, N., Laje, G., Landén, M., Lavebratt, C., Leboyer, M., Leckband, S. G., Jaramillo, C. A. L., MacQueen, G., Manchia, M., Martinsson, L., Mattheisen, M., McCarthy, M. J., McElroy, S. L., Mitjans, M., Mondimore, F. M., Monteleone, P., Nievergelt, C. M., Ösby, U., Ozaki, N., Perlis, R. H., Pfennig, A., Reich-Erkelenz, D., Rouleau, G. A., Schofield, P. R., Schubert, K. O., Schweizer, B. W., Seemüller, F., Severino, G., Shekhtman, T., Shilling, P. D., Shimoda, K., Simhandl, C., Slaney, C. M., Smoller, J. W., Squassina, A., Stamm, T. J., Stopkova, P., Tighe, S. K., Tortorella, A., Turecki, G., Volkert, J., Witt, S. H., Wright, A. J., Trevor Young, L., Zandi, P. P., Potash, J. B., DePaulo, J. R., Bauer, M., Reininghaus, E., Novák, T., Aubry, J. M., Maj, M., Baune, B. T., Mitchell, P. B., Vieta, E., Frye, M. A., Rybakowski, J. K., Kuo, P. H., Kato, T., Grigoroiu-Serbanescu, M., Reif, A., Zompo, M. D., Bellivier, F., Schalling, M., Wray, N. R., Kelsoe, J. R., Alda, M., McMahon, F. J., Schulze, T. G., Rietschel, M., Nöthen, M. M. & Cichon, S., May 31 2018, In : Frontiers in Psychiatry. 9, MAY, 207.

Research output: Contribution to journalArticle

MicroRNAs
Bipolar Disorder
Lithium
Genome-Wide Association Study
Genome
1 Citation (Scopus)

Application of the parametric bootstrap for gene-set analysis of gene–environment interactions

Coombes, B. J. & Biernacka, J. M., Jan 1 2018, (Accepted/In press) In : European Journal of Human Genetics.

Research output: Contribution to journalArticle

Genes
Wnt Signaling Pathway
Bipolar Disorder
Single Nucleotide Polymorphism
Obesity
28 Citations (Scopus)

Association of polygenic score for schizophrenia and HLA antigen and inflammation genes with response to lithium in bipolar affective disorder: A genome-wide association study

International Consortium on Lithium Genetics (ConLi+Gen), Jan 1 2018, In : JAMA Psychiatry. 75, 1, p. 65-74 10 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
HLA Antigens
Mood Disorders
Bipolar Disorder
Lithium
5 Citations (Scopus)

Association of schizophrenia polygenic risk score with manic and depressive psychosis in bipolar disorder

Markota, M., Coombes, B. J., Larrabee, B. R., McElroy, S. L., Bond, D. J., Veldic, M. D., Colby, C. L., Chauhan, M., Cuellar-Barboza, A. B., Fuentes, M., Kung, S., Prieto, M. L., Rummans, T. A., Bobo, W. V., Frye, M. A. & Biernacka, J. M., Dec 1 2018, In : Translational Psychiatry. 8, 1, 188.

Research output: Contribution to journalArticle

Bipolar Disorder
Psychotic Disorders
Schizophrenia
Phenotype
Depression
2 Citations (Scopus)

Association of the polygenic scores for personality traits and response to selective serotonin reuptake inhibitors in patients with major depressive disorder

Amare, A. T., Schubert, K. O., Tekola-Ayele, F., Hsu, Y. H., Sangkuhl, K., Jenkins, G., Whaley, R. M., Barman, P., Batzler, A., Altman, R. B., Arolt, V., Brockmöller, J., Chen, C. H., Domschke, K., Hall-Flavin, D. K., Hong, C. J., Illi, A., Ji, Y., Kampman, O., Kinoshita, T. & 17 others, Leinonen, E., Liou, Y. J., Mushiroda, T., Nonen, S., Skime, M. K., Wang, L. M., Kato, M., Liu, Y. L., Praphanphoj, V., Stingl, J. C., Bobo, W. V., Tsai, S. J., Kubo, M., Klein, T. E., Weinshilboum, R. M., Biernacka, J. M. & Baune, B. T., Mar 6 2018, In : Frontiers in Psychiatry. 9, MAR, 65.

Research output: Contribution to journalArticle

Major Depressive Disorder
Serotonin Uptake Inhibitors
Personality
Genome-Wide Association Study
Meta-Analysis
10 Citations (Scopus)

Beta-defensin 1, aryl hydrocarbon receptor and plasma kynurenine in major depressive disorder: Metabolomics-informed genomics

Liu, D., Ray, B., Neavin, D. R., Zhang, J., Athreya, A. P., Biernacka, J. M., Bobo, W. V., Hall-Flavin, D. K., Skime, M. K., Zhu, H., Jenkins, G. D., Batzler, A., Kalari, K. R., Boakye-Agyeman, F., Matson, W. R., Bhasin, S. S., Mushiroda, T., Nakamura, Y., Kubo, M., Iyer, R. K. & 4 others, Wang, L. M., Frye, M. A., Kaddurah-Daouk, R. & Weinshilboum, R. M., Dec 1 2018, In : Translational Psychiatry. 8, 1, 56.

Research output: Contribution to journalArticle

beta-Defensins
Kynurenine
Aryl Hydrocarbon Receptors
Metabolomics
Major Depressive Disorder
4 Citations (Scopus)

Bipolar disorder with binge eating behavior: A genome-wide association study implicates PRR5-ARHGAP8

McElroy, S. L., Winham, S. J., Cuellar-Barboza, A. B., Colby, C. L., Ho, A. M. C., Sicotte, H., Larrabee, B. R., Crow, S., Frye, M. A. & Biernacka, J. M., Dec 1 2018, In : Translational Psychiatry. 8, 1, 40.

Research output: Contribution to journalArticle

Bulimia
Genome-Wide Association Study
Feeding Behavior
Bipolar Disorder
Risk-Taking
3 Citations (Scopus)

Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: Meta-analysis of data from genome-wide association studies

Fabbri, C., Tansey, K. E., Perlis, R. H., Hauser, J., Henigsberg, N., Maier, W., Mors, O., Placentino, A., Rietschel, M., Souery, D., Breen, G., Curtis, C., Lee, S. H., Newhouse, S., Patel, H., O'Donovan, M., Lewis, G., Jenkins, G., Weinshilboum, R. M., Farmer, A. & 7 others, Aitchison, K. J., Craig, I., McGuffin, P., Schruers, K., Biernacka, J. M., Uher, R. & Lewis, C. M., Aug 1 2018, In : European Neuropsychopharmacology. 28, 8, p. 945-954 10 p.

Research output: Contribution to journalArticle

Citalopram
Genome-Wide Association Study
Cytochromes
Antidepressive Agents
Meta-Analysis
49 Citations (Scopus)

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium douglas.ruderfer@vanderbilt.edu, Psychosis Endophenotypes International Consortium & Wellcome Trust Case-Control Consortium, Jun 14 2018, In : Cell. 173, 7, p. 1705-1715.e16

Research output: Contribution to journalArticle

Dissection
Bipolar Disorder
Schizophrenia
Genes
Potassium

Identification of missing variants by combining multiple analytic pipelines

Ren, Y., Reddy, J. S., Pottier, C., Sarangi, V., Tian, S., Sinnwell, J. P., McDonnell, S. K., Biernacka, J. M., Carrasquillo, M. M., Ross, O. A., Taner, N., Rademakers, R. V., Hudson, M., Mainzer, L. S. & Asmann, Y., Apr 16 2018, In : BMC Bioinformatics. 19, 1, 139.

Research output: Contribution to journalArticle

Sample Size
Pipelines
Gene Frequency
Alzheimer Disease
Sequencing
1 Citation (Scopus)

Mapping depression rating scale phenotypes onto research domain criteria (RDoC) to inform biological research in mood disorders

The Mood Disorders Precision Medicine Consortium (MDPMC), Oct 1 2018, In : Journal of Affective Disorders. 238, p. 1-7 7 p.

Research output: Contribution to journalArticle

Mood Disorders
Depression
Phenotype
Research
Anxiety
9 Citations (Scopus)

New insights into the pharmacogenomics of antidepressant response from the GENDEP and STAR∗D studies: Rare variant analysis and high-density imputation

Fabbri, C., Tansey, K. E., Perlis, R. H., Hauser, J., Henigsberg, N., Maier, W., Mors, O., Placentino, A., Rietschel, M., Souery, D., Breen, G., Curtis, C., Sang-Hyuk, L., Newhouse, S., Patel, H., Guipponi, M., Perroud, N., Bondolfi, G., O'Donovan, M., Lewis, G. & 8 others, Biernacka, J. M., Weinshilboum, R. M., Farmer, A., Aitchison, K. J., Craig, I., McGuffin, P., Uher, R. & Lewis, C. M., May 22 2018, In : Pharmacogenomics Journal. 18, 3, p. 413-421 9 p.

Research output: Contribution to journalArticle

Pharmacogenetics
Antidepressive Agents
Gene Ontology
Exome
Single Nucleotide Polymorphism
2 Citations (Scopus)

PNPLA3 association with alcoholic liver disease in a cohort of heavy drinkers

Kolla, B. P., Schneekloth, T. D., Biernacka, J. M., Shah, V., Lazaridis, K. N., Geske, J. & Karpyak, V. M., Jan 1 2018, In : Alcohol and Alcoholism. 53, 4, p. 357-360 4 p.

Research output: Contribution to journalArticle

Alcoholic Liver Diseases
Liver
Polymorphism
Single Nucleotide Polymorphism
Nucleotides
5 Citations (Scopus)

Polygenic risk scores for major depressive disorder and neuroticism as predictors of antidepressant response: Meta-analysis of three treatment cohorts

Ward, J., Graham, N., Strawbridge, R. J., Ferguson, A., Jenkins, G., Chen, W., Hodgson, K., Frye, M. A., Weinshilboum, R. M., Uher, R., Lewis, C. M., Biernacka, J. M. & Smith, D. J., Sep 1 2018, In : PLoS One. 13, 9, e0203896.

Research output: Contribution to journalArticle

antidepressants
Major Depressive Disorder
meta-analysis
Antidepressive Agents
Meta-Analysis
11 Citations (Scopus)

Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study

Pottier, C., Zhou, X., Perkerson, R. B., Baker, M., Jenkins, G. D., Serie, D. J., Ghidoni, R., Benussi, L., Binetti, G., López de Munain, A., Zulaica, M., Moreno, F., Le Ber, I., Pasquier, F., Hannequin, D., Sánchez-Valle, R., Antonell, A., Lladó, A., Parsons, T. M., Finch, N. C. A. & 113 others, Finger, E. C., Lippa, C. F., Huey, E. D., Neumann, M., Heutink, P., Synofzik, M., Wilke, C., Rissman, R. A., Slawek, J., Sitek, E., Johannsen, P., Nielsen, J. E., Ren, Y., Van Blitterswijk, M., DeJesus-Hernandez, M., Christopher, E., Murray, M. E., Bieniek, K. F., Evers, B. M., Ferrari, C., Rollinson, S., Richardson, A., Scarpini, E., Fumagalli, G. G., Padovani, A., Hardy, J., Momeni, P., Ferrari, R., Frangipane, F., Maletta, R., Anfossi, M., Gallo, M., Petrucelli, L., Suh, E. R., Lopez, O. L., Wong, T. H., van Rooij, J. G. J., Seelaar, H., Mead, S., Caselli, R. J., Reiman, E. M., Noel Sabbagh, M., Kjolby, M., Nykjaer, A., Karydas, A. M., Boxer, A. L., Grinberg, L. T., Grafman, J., Spina, S., Oblak, A., Mesulam, M. M., Weintraub, S., Geula, C., Hodges, J. R., Piguet, O., Brooks, W. S., Irwin, D. J., Trojanowski, J. Q., Lee, E. B., Josephs, K. A., Parisi, J. E., Taner, N., Knopman, D. S., Nacmias, B., Piaceri, I., Bagnoli, S., Sorbi, S., Gearing, M., Glass, J., Beach, T. G., Black, S. E., Masellis, M., Rogaeva, E., Vonsattel, J. P., Honig, L. S., Kofler, J., Bruni, A. C., Snowden, J., Mann, D., Pickering-Brown, S., Diehl-Schmid, J., Winkelmann, J., Galimberti, D., Graff, C., Öijerstedt, L., Troakes, C., Al-Sarraj, S., Cruchaga, C., Cairns, N. J., Rohrer, J. D., Halliday, G. M., Kwok, J. B., van Swieten, J. C., White, C. L., Ghetti, B., Murell, J. R., Mackenzie, I. R. A., Hsiung, G. Y. R., Borroni, B., Rossi, G., Tagliavini, F., Wszolek, Z. K., Petersen, R. C., Bigio, E. H., Grossman, M., Van Deerlin, V. M., Seeley, W. W., Miller, B. L., Graff Radford, N. R., Boeve, B. F., Dickson, D. W., Biernacka, J. M. & Rademakers, R. V., Jun 1 2018, In : The Lancet Neurology. 17, 6, p. 548-558 11 p.

Research output: Contribution to journalArticle

Frontotemporal Lobar Degeneration
Inborn Genetic Diseases
Genome-Wide Association Study
Age of Onset
Meta-Analysis
4 Citations (Scopus)

Racial disparities in bipolar disorder treatment and research: A call to action

Akinhanmi, M. O., Biernacka, J. M., Strakowski, S. M., Mcelroy, S. L., Balls-Berry, J., Merikangas, K. R., Assari, S., Mcinnis, M. G., Schulze, T. G., Leboyer, M., Tamminga, C., Patten, C. A. & Frye, M. A., Jan 1 2018, (Accepted/In press) In : Bipolar Disorders.

Research output: Contribution to journalArticle

Bipolar Disorder
Racism
Diagnostic Errors
Research
International Classification of Diseases
8 Citations (Scopus)

The relative influence of individual risk factors for attempted suicide in patients with bipolar I versus bipolar II disorder

Bobo, W. V., Na, P. J., Geske, J. R., McElroy, S. L., Frye, M. A. & Biernacka, J. M., Jan 1 2018, In : Journal of Affective Disorders. 225, p. 489-494 6 p.

Research output: Contribution to journalArticle

Attempted Suicide
Bipolar Disorder
Psychiatry
Suicide
Body Mass Index
33 Citations (Scopus)

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

23andMe Research Team, Dec 1 2018, In : Nature Neuroscience. 21, 12, p. 1656-1669 14 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Alcoholism
Psychiatry
Genome
Drinking Behavior
2017
5 Citations (Scopus)

A genome wide association study suggests the association of muskelin with early onset bipolar disorder: Implications for a GABAergic epileptogenic neurogenesis model

Nassan, M., Li, Q., Croarkin, P. E., Chen, W., Colby, C. L., Veldic, M. D., McElroy, S. L., Jenkins, G. D., Ryu, E., Cunningham, J. M., Leboyer, M., Frye, M. A. & Biernacka, J. M., Jan 15 2017, In : Journal of Affective Disorders. 208, p. 120-129 10 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Neurogenesis
Bipolar Disorder
Single Nucleotide Polymorphism
GABA-A Receptors
1 Citation (Scopus)

Association of the serotonin transporter-linked polymorphic region genotype with lower bone mineral density

Lapid, M. I., Kung, S., Frye, M. A., Biernacka, J. M., Geske, J. R., Drake, M. M., Jankowski, M. D. & Clarke, B., Aug 22 2017, In : Translational Psychiatry. 7, 8, p. e1213

Research output: Contribution to journalArticle

Serotonin Plasma Membrane Transport Proteins
Bone Density
Alleles
Genotype
Spine
5 Citations (Scopus)

Differential SLC1A2 promoter methylation in bipolar disorder with or without addiction

Jia, Y. F., Choi, Y. B., Ayers-Ringler, J. R., Biernacka, J. M., Geske, J. R., Lindberg, D. R., McElroy, S. L., Frye, M. A., Choi, D. S. & Veldic, M. D., Jul 21 2017, In : Frontiers in Cellular Neuroscience. 11, 217.

Research output: Contribution to journalArticle

Bipolar Disorder
Methylation
Excitatory Amino Acid Transporter 2
Nicotine
Genetic Promoter Regions
2 Citations (Scopus)

Exploring hepsin functional genetic variation association with disease specific protein expression in bipolar disorder: Applications of a proteomic informed genomic approach

Nassan, M., Jia, Y. F., Jenkins, G., Colby, C., Feeder, S., Choi, D. S., Veldic, M. D., McElroy, S. L., Bond, D. J., Weinshilboum, R. M., Biernacka, J. M. & Frye, M. A., Dec 1 2017, In : Journal of Psychiatric Research. 95, p. 208-212 5 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Proteomics
Quantitative Trait Loci
Alleles
Proteins
4 Citations (Scopus)

Genetic risk score analysis in early-onset bipolar disorder

Croarkin, P. E., Luby, J. L., Cercy, K., Geske, J. R., Veldic, M. D., Simonson, M., Joshi, P. T., Wagner, K. D., Walkup, J. T., Nassan, M. M., Cuellar-Barboza, A. B., Casuto, L., McElroy, S. L., Jensen, P. S., Frye, M. A. & Biernacka, J. M., Nov 1 2017, In : Journal of Clinical Psychiatry. 78, 9, p. 1337-1343 7 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Single Nucleotide Polymorphism
Ankyrins
Haplotypes
Ranvier's Nodes
28 Citations (Scopus)

Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia

Schizophrenia Working Group of the Psychiatric Genomics Consortium, Bipolar Disorders Working Group of the Psychiatric Genomics Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Jun 20 2017, In : Translational Psychiatry. 7, 6, p. e1155

Research output: Contribution to journalArticle

Borderline Personality Disorder
Genome-Wide Association Study
Bipolar Disorder
Schizophrenia
Depression
9 Citations (Scopus)

Metabolomics biomarkers to predict acamprosate treatment response in alcohol-dependent subjects

Hinton, D. J., Vázquez, M. S., Geske, J. R., Hitschfeld, M. J., Ho, A. M. C., Karpyak, V. M., Biernacka, J. M. & Choi, D. S., Dec 1 2017, In : Scientific Reports. 7, 1, 2496.

Research output: Contribution to journalArticle

Metabolomics
Biomarkers
Alcohols
Alcohol Drinking
Therapeutics
4 Citations (Scopus)

Mitochondrial DNA sequence data reveals association of haplogroup U with psychosis in bipolar disorder

Frye, M. A., Ryu, E., Nassan, M., Jenkins, G. D., Andreazza, A. C., Evans, J. M., McElroy, S. L., Oglesbee, D., Highsmith, W. E. J. & Biernacka, J. M., Jan 1 2017, In : Journal of Psychiatric Research. 84, p. 221-226 6 p.

Research output: Contribution to journalArticle

Mitochondrial DNA
Bipolar Disorder
Psychotic Disorders
Genes
Phenotype
2016
12 Citations (Scopus)

Accumulating evidence for a role of TCF7L2 variants in bipolar disorder with elevated body mass index

Cuellar-Barboza, A. B., Winham, S. J., Mcelroy, S. L., Geske, J. R., Jenkins, G. D., Colby, C. L., Prieto, M. L., Ryu, E., Cunningham, J. M., Frye, M. A. & Biernacka, J. M., Mar 1 2016, In : Bipolar Disorders. 18, 2, p. 124-135 12 p.

Research output: Contribution to journalArticle

T Cell Transcription Factor 1
Bipolar Disorder
Body Mass Index
Single Nucleotide Polymorphism
Wnt Signaling Pathway
9 Citations (Scopus)

Anterior Cingulate Glutamate Is Reduced by Acamprosate Treatment in Patients with Alcohol Dependence

Frye, M. A., Hinton, D. J., Karpyak, V. M., Biernacka, J. M., Gunderson, L. J., Feeder, S. E., Choi, D. S. & Port, J. D., Dec 1 2016, In : Journal of Clinical Psychopharmacology. 36, 6, p. 669-674 6 p.

Research output: Contribution to journalArticle

Gyrus Cinguli
Alcoholism
Glutamic Acid
Therapeutics
Alcohols
10 Citations (Scopus)

Clinical features of bipolar spectrum with binge eating behaviour

McElroy, S. L., Crow, S., Blom, T. J., Cuellar-Barboza, A. B., Prieto, M. L., Veldic, M. D., Winham, S. J., Bobo, W. V., Geske, J., Seymour, L. R., Mori, N., Bond, D. J., Biernacka, J. M. & Frye, M. A., Sep 1 2016, In : Journal of Affective Disorders. 201, p. 95-98 4 p.

Research output: Contribution to journalArticle

Bulimia
Feeding Behavior
Cost of Illness
Bipolar Disorder
Comorbidity
5 Citations (Scopus)

Elevated Glutamate Levels in the Left Dorsolateral Prefrontal Cortex Are Associated with Higher Cravings for Alcohol

Frye, M. A., Hinton, D. J., Karpyak, V. M., Biernacka, J. M., Gunderson, L. J., Geske, J., Feeder, S. E., Choi, D. S. & Port, J. D., Aug 1 2016, In : Alcoholism: Clinical and Experimental Research. 40, 8, p. 1609-1616 8 p.

Research output: Contribution to journalArticle

Prefrontal Cortex
Glutamic Acid
Alcohols
Cerebrospinal fluid
Aspartic Acid
13 Citations (Scopus)

Gender-specific effects of comorbid depression and anxiety on the propensity to drink in negative emotional states

Karpyak, V. M., Biernacka, J. M., Geske, J. R., Abulseoud, O. A., Brunner, M. D., Chauhan, M., Hall-Flavin, D. K., Lewis, K. A., Loukianova, L. L., Melnyk, G. J., Onsrud, D. A., Proctor, B. D., Schneekloth, T. D., Skime, M. K., Wittkopp, J. E., Frye, M. A. & Mrazek, D. A., 2016, (Accepted/In press) In : Addiction.

Research output: Contribution to journalArticle

Anxiety
Depression
Anxiety Disorders
Major Depressive Disorder
Alcoholism
96 Citations (Scopus)

Genetic variants associated with response to lithium treatment in bipolar disorder: A genome-wide association study

Hou, L., Heilbronner, U., Degenhardt, F., Adli, M., Akiyama, K., Akula, N., Ardau, R., Arias, B., Backlund, L., Banzato, C. E. M., Benabarre, A., Bengesser, S., Bhattacharjee, A. K., Biernacka, J. M., Birner, A., Brichant-Petitjean, C., Bui, E. T., Cervantes, P., Chen, G. B., Chen, H. C. & 103 others, Chillotti, C., Cichon, S., Clark, S. R., Colom, F., Cousins, D. A., Cruceanu, C., Czerski, P. M., Dantas, C. R., Dayer, A., Étain, B., Falkai, P., Forstner, A. J., Frisén, L., Fullerton, J. M., Gard, S., Garnham, J. S., Goes, F. S., Grof, P., Gruber, O., Hashimoto, R., Hauser, J., Herms, S., Hoffmann, P., Hofmann, A., Jamain, S., Jiménez, E., Kahn, J. P., Kassem, L., Kittel-Schneider, S., Kliwicki, S., König, B., Kusumi, I., Lackner, N., Laje, G., Landén, M., Lavebratt, C., Leboyer, M., Leckband, S. G., Jaramillo, C. A. L., Macqueen, G., Manchia, M., Martinsson, L., Mattheisen, M., McCarthy, M. J., McElroy, S. L., Mitjans, M., Mondimore, F. M., Monteleone, P., Nievergelt, C. M., Nöthen, M. M., Ösby, U., Ozaki, N., Perlis, R. H., Pfennig, A., Reich-Erkelenz, D., Rouleau, G. A., Schofield, P. R., Schubert, K. O., Schweizer, B. W., Seemüller, F., Severino, G., Shekhtman, T., Shilling, P. D., Shimoda, K., Simhandl, C., Slaney, C. M., Smoller, J. W., Squassina, A., Stamm, T., Stopkova, P., Tighe, S. K., Tortorella, A., Turecki, G., Volkert, J., Witt, S., Wright, A., Young, L. T., Zandi, P. P., Potash, J. B., Depaulo, J. R., Bauer, M., Reininghaus, E. Z., Novák, T., Aubry, J. M., Maj, M., Baune, B. T., Mitchell, P. B., Vieta, E., Frye, M. A., Rybakowski, J. K., Kuo, P. H., Kato, T., Grigoroiu-Serbanescu, M., Reif, A., Del Zompo, M., Bellivier, F., Schalling, M., Wray, N. R., Kelsoe, J. R., Alda, M., Rietschel, M., McMahon, F. J. & Schulze, T. G., Mar 12 2016, In : The Lancet. 387, 10023, p. 1085-1093 9 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Bipolar Disorder
Lithium
Single Nucleotide Polymorphism
Therapeutics
12 Citations (Scopus)

Genome-wide gene-environment interaction analysis of pesticide exposure and risk of Parkinson's disease

Biernacka, J. M., Chung, S. J., Armasu, S. M., Anderson, K. S., Lill, C. M., Bertram, L., Ahlskog, J. E., Brighina, L., Frigerio, R. & Maraganore, D. M., Nov 1 2016, In : Parkinsonism and Related Disorders. 32, p. 25-30 6 p.

Research output: Contribution to journalArticle

Gene-Environment Interaction
Pesticides
Parkinson Disease
Genome
Genes