Projects per year
Personal profile
Research Interests
The laboratory-based research program of Gregory J. Gores, M.D., is focused on mechanisms of liver cell death, especially apoptosis. He employs disease-relevant models to unravel the fundamental cellular processes contributing to liver injury during cholestasis and fatty liver diseases. In addition, Dr. Gores' lab is also interested in the mechanisms by which cancer cells escape from cell death in order to undergo malignant transformation and metastases.
URL
Areas of Research
- Gastrointestinal Cancer Program
- Cholestatic Liver Diseases
- Mayo Clinic Cancer Center - Research
- Advanced Liver Diseases: Patrick S. Kamath, Vijay Shah
- Center for Clinical and Translational Science (CCaTS)
- Liver Pathobiology - Gregory J. Gores
- Center for Cell Signaling in Gastroenterology (C-SiG)
- Physiology and Biomedical Engineering
- Gastroenterology and Hepatology Research
- Transplant Research Center
- Center for Regenerative Medicine
Faculty Profile:
Clinical Profile:
Gastroenterologist, Internist
Research Interests
The laboratory-based research program of Gregory J. Gores, M.D., is focused on mechanisms of liver cell death, especially apoptosis. He employs disease-relevant models to unravel the fundamental cellular processes contributing to liver injury during cholestasis and fatty liver diseases. In addition, Dr. Gores' lab is also interested in the mechanisms by which cancer cells escape from cell death in order to undergo malignant transformation and metastases.
URL
Areas of Research
- Gastrointestinal Cancer Program
- Cholestatic Liver Diseases
- Mayo Clinic Cancer Center - Research
- Advanced Liver Diseases: Patrick S. Kamath, Vijay Shah
- Center for Clinical and Translational Science (CCaTS)
- Liver Pathobiology - Gregory J. Gores
- Center for Cell Signaling in Gastroenterology (C-SiG)
- Physiology and Biomedical Engineering
- Gastroenterology and Hepatology Research
- Transplant Research Center
- Center for Regenerative Medicine
Faculty Profile:
Clinical Profile:
Gastroenterologist, Internist
Education/Academic qualification
Mayo Graduate School of Medicine, Mayo Clinic College of Medicine
University of North Dakota
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Cholestatic Liver Injury
National Institute of Diabetes and Digestive and Kidney Diseases
Project: Research project
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Multidisciplinary Training in Digestive Diseases
La Russo, N. F., Gores, G. J. & Faubion, W. A.
Project: Research project
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Research output
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Bile Acid Profiles in Primary Sclerosing Cholangitis and Their Ability to Predict Hepatic Decompensation
Mousa, O. Y., Juran, B. D., McCauley, B. M., Vesterhus, M. N., Folseraas, T., Turgeon, C. T., Ali, A. H., Schlicht, E. M., Atkinson, E. J., Hu, C., Harnois, D., Carey, E. J., Gossard, A. A., Oglesbee, D., Eaton, J. E., LaRusso, N. F., Gores, G. J., Karlsen, T. H. & Lazaridis, K. N., Jul 2021, In: Hepatology. 74, 1, p. 281-295 15 p.Research output: Contribution to journal › Article › peer-review
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CD40-mediated immune cell activation enhances response to anti-PD-1 in murine intrahepatic cholangiocarcinoma
Diggs, L. P., Ruf, B., Ma, C., Heinrich, B., Cui, L., Zhang, Q., McVey, J. C., Wabitsch, S., Heinrich, S., Rosato, U., Lai, W., Subramanyam, V., Longerich, T., Loosen, S. H., Luedde, T., Neumann, U. P., Desar, S., Kleiner, D., Gores, G., Wang, X. W. & 1 others, , May 2021, In: Journal of hepatology. 74, 5, p. 1145-1154 10 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Cerebral Venous Sinus Thrombosis is not Significantly Linked to COVID-19 Vaccines or Non-COVID Vaccines in a Large Multi-State Health System
Pawlowski, C., Rincón-Hekking, J., Awasthi, S., Pandey, V., Lenehan, P., Venkatakrishnan, A. J., Bade, S., O'Horo, J. C., Virk, A., Swift, M. D., Williams, A. W., Gores, G. J., Badley, A. D., Halamka, J. & Soundararajan, V., 2021, (Accepted/In press) In: Journal of Stroke and Cerebrovascular Diseases. 105923.Research output: Contribution to journal › Article › peer-review
Open Access -
Circulating Extracellular Vesicles Carrying Sphingolipid Cargo for the Diagnosis and Dynamic Risk Profiling of Alcoholic Hepatitis
Sehrawat, T. S., Arab, J. P., Liu, M., Amrollahi, P., Wan, M., Fan, J., Nakao, Y., Pose, E., Navarro-Corcuera, A., Dasgupta, D., Liao, C. Y., He, L., Mauer, A. S., Avitabile, E., Ventura-Cots, M., Bataller, R. A., Sanyal, A. J., Chalasani, N. P., Heimbach, J. K., Watt, K. D. & 7 others, , Feb 2021, In: Hepatology. 73, 2, p. 571-585 15 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
Direct-Acting Antiviral Therapy in Liver Transplant Patients with Hepatocellular Carcinoma and Hepatitis C
Tse, C. S., Yang, J. D., Mousa, O. Y., Nelson, K. M., Pungpapong, S., Keaveny, A., Aqel, B. A., Vargas, H., Dickson, R. C., Watt, K., Gores, G. J., Roberts, L. R. & Leise, M. D., 2021, (Accepted/In press) In: Transplantation Direct. e635.Research output: Contribution to journal › Article › peer-review
Open Access