Projects per year
Personal profile
Research Interests
The laboratory-based research program of Gregory J. Gores, M.D., is focused on mechanisms of liver cell death, especially apoptosis. He employs disease-relevant models to unravel the fundamental cellular processes contributing to liver injury during cholestasis and fatty liver diseases. In addition, Dr. Gores' lab is also interested in the mechanisms by which cancer cells escape from cell death in order to undergo malignant transformation and metastases.
URL
Areas of Research
- Gastrointestinal Cancer Program
- Cholestatic Liver Diseases
- Mayo Clinic Cancer Center - Research
- Advanced Liver Diseases: Patrick S. Kamath, Vijay Shah
- Center for Clinical and Translational Science (CCaTS)
- Liver Pathobiology - Gregory J. Gores
- Center for Cell Signaling in Gastroenterology (C-SiG)
- Physiology and Biomedical Engineering
- Gastroenterology and Hepatology Research
- Transplant Research Center
- Center for Regenerative Medicine
Faculty Profile:
Clinical Profile:
Gastroenterologist, Internist
Research Interests
The laboratory-based research program of Gregory J. Gores, M.D., is focused on mechanisms of liver cell death, especially apoptosis. He employs disease-relevant models to unravel the fundamental cellular processes contributing to liver injury during cholestasis and fatty liver diseases. In addition, Dr. Gores' lab is also interested in the mechanisms by which cancer cells escape from cell death in order to undergo malignant transformation and metastases.
URL
Areas of Research
- Gastrointestinal Cancer Program
- Cholestatic Liver Diseases
- Mayo Clinic Cancer Center - Research
- Advanced Liver Diseases: Patrick S. Kamath, Vijay Shah
- Center for Clinical and Translational Science (CCaTS)
- Liver Pathobiology - Gregory J. Gores
- Center for Cell Signaling in Gastroenterology (C-SiG)
- Physiology and Biomedical Engineering
- Gastroenterology and Hepatology Research
- Transplant Research Center
- Center for Regenerative Medicine
Faculty Profile:
Clinical Profile:
Gastroenterologist, Internist
Education/Academic qualification
Mayo Graduate School of Medicine, Mayo Clinic College of Medicine
University of North Dakota
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Projects
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Cholestatic Liver Injury
National Institute of Diabetes and Digestive and Kidney Diseases
Project: Research project
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Core A: Administrative Core
Gores, G. J., Vile, R. G., Leof, E. B., Mandrekar, S. J., Torbenson, M. & Alberts, S. R.
Project: Research project
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Mayo Center for Cell Signaling in Gastroenterology
Ekker, S. C., Mc Niven, M. A., Mc Niven, M. A., Farrugia, G., Mc Niven, M. A., La Russo, N. F., La Russo, N. F., Ekker, S. C., Boardman, L. A., Farrugia, G., Faubion, W. A. & Gores, G. J.
National Institute of Diabetes and Digestive and Kidney Diseases
9/1/09 → 8/31/19
Project: Research project
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Organelle Dysfunction and Apoptosis in Liver Epithelia
Gores, G. J., Kinney, L. & Kinney, L.
National Institute of Diabetes and Digestive and Kidney Diseases
8/1/03 → 5/31/17
Project: Research project
Research output
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CD40-mediated immune cell activation enhances response to anti-PD-1 in murine intrahepatic cholangiocarcinoma
Diggs, L. P., Ruf, B., Ma, C., Heinrich, B., Cui, L., Zhang, Q., McVey, J. C., Wabitsch, S., Heinrich, S., Rosato, U., Lai, W., Subramanyam, V., Longerich, T., Loosen, S. H., Luedde, T., Neumann, U. P., Desar, S., Kleiner, D., Gores, G., Wang, X. W. & 1 others, , 2021, (Accepted/In press) In: Journal of hepatology.Research output: Contribution to journal › Article › peer-review
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Exploratory analysis of immunization records highlights decreased SARS-CoV-2 rates in individuals with recent non-COVID-19 vaccinations
Pawlowski, C., Puranik, A., Bandi, H., Venkatakrishnan, A. J., Agarwal, V., Kennedy, R., O’Horo, J. C., Gores, G. J., Williams, A. W., Halamka, J., Badley, A. D. & Soundararajan, V., Dec 2021, In: Scientific reports. 11, 1, 4741.Research output: Contribution to journal › Article › peer-review
Open Access -
Plasma IL-6 levels following corticosteroid therapy as an indicator of ICU length of stay in critically ill COVID-19 patients
Awasthi, S., Wagner, T., Venkatakrishnan, A. J., Puranik, A., Hurchik, M., Agarwal, V., Conrad, I., Kirkup, C., Arunachalam, R., O’Horo, J., Kremers, W., Kashyap, R., Morice, W., Halamka, J., Williams, A. W., Faubion, W. A., Badley, A. D., Gores, G. J. & Soundararajan, V., Jun 2021, In: Cell Death Discovery. 7, 1, 55.Research output: Contribution to journal › Article › peer-review
Open Access -
The Difference a Decade Makes
Gores, G. J., McNiven, M. A. & Roberts, L. R., Jan 2021, In: Hepatology. 73, S1, p. 1-3 3 p.Research output: Contribution to journal › Comment/debate › peer-review
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An Open-Label, Dose-Escalation Study to Assess the Safety and Efficacy of IL-22 Agonist F-652 in Patients With Alcohol-associated Hepatitis
Arab, J. P., Sehrawat, T. S., Simonetto, D. A., Verma, V. K., Feng, D., Tang, T., Dreyer, K., Yan, X., Daley, W. L., Sanyal, A., Chalasani, N., Radaeva, S., Yang, L., Vargas, H., Ibacache, M., Gao, B., Gores, G. J., Malhi, H., Kamath, P. S. & Shah, V. H., Aug 1 2020, In: Hepatology. 72, 2, p. 441-453 13 p.Research output: Contribution to journal › Article › peer-review
23 Scopus citations