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Dive into the research topics where Georges Mer is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Targeted Inhibition of DNA Repair Protein TIRR with Aptamers to Counteract Resistance of Ovarian Cancer Cells to PARP Inhibitors
6/1/20 → 6/1/20
Project: Research project
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Post-translational Modifications in DNA Damage Response: a Structural Perspective
4/1/08 → 5/31/20
Project: Research project
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Visualizing both nucleosome disassembly and reassembly during FACT chaperone activity
McCauley, M. J., Morse, M., Becker, N. A., Hu, Q., Botuyan, M. V., Navarrete, E., Huo, R., Muthurajan, U., Rouzina, I. F., Luger, K., Mer, G., Maher, L. J. & Williams, M. C., Feb 10 2023, In: Biophysical Journal. 122, 3S1, p. 129aResearch output: Contribution to journal › Article › peer-review
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A novel missense HNRNPA1 variant in the PY-NLS domain in a patient with late-onset distal myopathy
Chompoopong, P., Milone, M., Niu, Z., Cui, G., Mer, G. & Liewluck, T., Jun 2022, In: Neuromuscular Disorders. 32, 6, p. 521-526 6 p.Research output: Contribution to journal › Article › peer-review
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Human FACT subunits coordinate to catalyze both disassembly and reassembly of nucleosomes
McCauley, M. J., Morse, M., Becker, N., Hu, Q., Botuyan, M. V., Navarrete, E., Huo, R., Muthurajan, U. M., Rouzina, I., Luger, K., Mer, G., Maher, L. J. & Williams, M. C., Dec 27 2022, In: Cell reports. 41, 13, 111858.Research output: Contribution to journal › Article › peer-review
Open Access -
METTL16 antagonizes MRE11-mediated DNA end resection and confers synthetic lethality to PARP inhibition in pancreatic ductal adenocarcinoma
Zeng, X., Zhao, F., Cui, G., Zhang, Y., Deshpande, R. A., Chen, Y., Deng, M., Kloeber, J. A., Shi, Y., Zhou, Q., Zhang, C., Hou, J., Kim, W., Tu, X., Yan, Y., Xu, Z., Chen, L., Gao, H., Guo, G., Liu, J., & 12 others, Sep 2022, In: Nature Cancer. 3, 9, p. 1088-1104 17 p.Research output: Contribution to journal › Article › peer-review
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A rare germline CDKN2A variant (47T>G; p16-L16R) predisposes carriers to pancreatic cancer by reducing cell cycle inhibition
Horn, I. P., Marks, D. L., Koenig, A. N., Hogenson, T. L., Almada, L. L., Goldstein, L. E., Romecin Duran, P. A., Vera, R., Vrabel, A. M., Cui, G., Rabe, K. G., Bamlet, W. R., Mer, G., Sicotte, H., Zhang, C., Li, H., Petersen, G. M. & Fernandez-Zapico, M. E., Apr 3 2021, In: Journal of Biological Chemistry. 296, 100634.Research output: Contribution to journal › Article › peer-review
Open Access