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Georges Mer, PhD

  • 3771 Citations
  • 27 Scopus h-Index
1991 …2019
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Histones Medicine & Life Sciences
Lysine Medicine & Life Sciences
DNA Damage Medicine & Life Sciences
Peptides Medicine & Life Sciences
Proteins Medicine & Life Sciences
Chromatin Medicine & Life Sciences
Acetylation Medicine & Life Sciences
Nucleosomes Medicine & Life Sciences

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Projects 2004 2019

Structural basis of RNF168-mediated ubiquitin signaling at chromosomal DNA breaks

Mer, G.

National Institutes of Health

9/22/15 → 8/31/19

Project: Research project

Chromosome Breakage
DNA Breaks
Ubiquitin
Histones
Homologous Recombination

Structural Biology of Lysine Methylation in DNA Damage and Checkpoint Signaling

Mer, G.

National Institutes of Health

4/1/08 → 11/30/18

Project: Research project

DNA Damage
Histones
Lysine
Methylation
Post Translational Protein Processing

Structural Basis of Cell Signaling by BRCT Domains

Mer, G.

National Institutes of Health

7/15/04 → 4/30/10

Project: Research project

Phosphoproteins
Tandem Repeat Sequences
Phosphopeptides
Proteins
Histones

Research Output 1991 2018

  • 3771 Citations
  • 27 Scopus h-Index
  • 57 Article
  • 2 Chapter
  • 1 Short survey
6 Citations (Scopus)

Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein

Botuyan, M. V., Cui, G., Drané, P., Oliveira, C., Detappe, A., Brault, M. E., Parnandi, N., Chaubey, S., Thompson, J. R., Bragantini, B., Zhao, D., Chapman, J. R., Chowdhury, D. & Mer, G., Jul 2 2018, (Accepted/In press) In : Nature Structural and Molecular Biology. p. 1-10 10 p.

Research output: Contribution to journal › Article

RNA
Post Translational Protein Processing
Chromatin
Protein Interaction Maps
Proteins
1 Citation (Scopus)

Structural Basis for the Interaction of Mutasome Assembly Factor REV1 with Ubiquitin

Cui, G., Botuyan, M. V. & Mer, G., Jul 6 2018, In : Journal of Molecular Biology. 430, 14, p. 2042-2050 9 p.

Research output: Contribution to journal › Article

Ubiquitin
DNA Damage
Mutagenesis
Nuclear Antigens
DNA-Directed DNA Polymerase

A New BRCT Binding Mode in TopBP1-BLM Helicase Interaction

Mer, G. & Botuyan, M. V., Oct 3 2017, In : Structure. 25, 10, p. 1471-1472 2 p.

Research output: Contribution to journal › Short survey

Bloom Syndrome
Solar System
Bloom syndrome protein
9 Citations (Scopus)

Genomic analysis reveals frequent TRAF7 mutations in intraneural perineuriomas

Klein, C. J., Wu, Y., Jentoft, M. E., Mer, G., Spinner, R. J., Dyck, P. J. B., Dyck, P. J. & Mauermann, M. M., Feb 1 2017, In : Annals of Neurology. 81, 2, p. 316-321 6 p.

Research output: Contribution to journal › Article

Nerve Sheath Neoplasms
Mutation
Meningioma
Chromosomes
Exome
22 Citations (Scopus)

Mechanisms of Ubiquitin-Nucleosome Recognition and Regulation of 53BP1 Chromatin Recruitment by RNF168/169 and RAD18

Hu, Q., Botuyan, M. V., Cui, G., Zhao, D. & Mer, G., May 18 2017, In : Molecular Cell. 66, 4, p. 473-487.e9

Research output: Contribution to journal › Article

Nucleosomes
Ubiquitin
Chromatin
Histones
Double-Stranded DNA Breaks