Projects per year
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Dive into the research topics where Georges Mer is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Post-translational Modifications in DNA Damage Response: a Structural Perspective
4/1/08 → 12/31/24
Project: Research project
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Structural biology of DNA damage response in chromatin
National Institute of General Medical Sciences
5/1/20 → 2/29/24
Project: Research project
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Structural basis of RNF168-mediated ubiquitin signaling at chromosomal DNA breaks
National Institute of General Medical Sciences
9/22/15 → 8/31/20
Project: Research project
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Adolescent-onset multisystem proteinopathy due to a novel VCP variant
Soontrapa, P., Seven, N. A., Liewluck, T., Cui, G., Mer, G. & Milone, M., Jan 2024, In: Neuromuscular Disorders. 34, p. 89-94 6 p.Research output: Contribution to journal › Article › peer-review
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Quantifying ATP-Independent Nucleosome Chaperone Activity with Single-Molecule Methods
McCauley, M. J., Joshi, J., Becker, N., Hu, Q., Botuyan, M. V., Rouzina, I., Mer, G., James Maher, L. & Williams, M. C., 2024, Methods in Molecular Biology. Humana Press Inc., p. 29-55 27 p. (Methods in Molecular Biology; vol. 2694).Research output: Chapter in Book/Report/Conference proceeding › Chapter
Open Access -
A chemical strategy to study transient states in substrate ubiquitylation by cryo-EM
Hu, Q., Botuyan, M. V. & Mer, G., May 11 2023, In: Chem. 9, 5, p. 1069-1071 3 p.Research output: Contribution to journal › Comment/debate › peer-review
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An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering
Cui, G., Botuyan, M. V., Drané, P., Hu, Q., Bragantini, B., Thompson, J. R., Schuller, D. J., Detappe, A., Perfetti, M. T., James, L. I., Frye, S. V., Chowdhury, D. & Mer, G., Dec 2023, In: Nature communications. 14, 1, 6091.Research output: Contribution to journal › Article › peer-review
Open Access -
Functional and Clinical Characterization of Variants of Uncertain Significance Identifies a Hotspot for Inactivating Missense Variants in RAD51C
Hu, C., Nagaraj, A. B., Shimelis, H., Montalban, G., Lee, K. Y., Huang, H., Lumby, C. A., Na, J., Susswein, L. R., Roberts, M. E., Marshall, M. L., Hiraki, S., LaDuca, H., Chao, E., Yussuf, A., Pesaran, T., Neuhausen, S. L., Haiman, C. A., Kraft, P., Lindstrom, S., & 24 others , Aug 1 2023, In: Cancer research. 83, 15, p. 2557-2571 15 p.Research output: Contribution to journal › Article › peer-review
Open Access