Fergus J Couch

Fergus J Couch, PhD

Chair, Division of Experimental Pathology

1991 …2023

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  • Article

    Genome-wide association study identifies novel breast cancer susceptibility loci

    Easton, D. F., Pooley, K. A., Dunning, A. M., Pharoah, P. D. P., Thompson, D., Ballinger, D. G., Struewing, J. P., Morrison, J., Field, H., Luben, R., Wareham, N., Ahmed, S., Healey, C. S., Bowman, R., Meyer, K. B., Haiman, C. A., Kolonel, L. K., Henderson, B. E., Le Marchand, L., Brennan, P., & 212 othersSangrajrang, S., Gaborieau, V., Odefrey, F., Shen, C. Y., Wu, P. E., Wang, H. C., Eccles, D., Evans, D. G., Peto, J., Fletcher, O., Johnson, N., Seal, S., Stratton, M. R., Rahman, N., Chenevix-Trench, G., Bojesen, S. E., Nordestgaard, B. G., Axelsson, C. K., Garcia-Closas, M., Brinton, L., Chanock, S., Lissowska, J., Peplonska, B., Nevanlinna, H., Fagerholm, R., Eerola, H., Kang, D., Yoo, K. Y., Noh, D. Y., Ahn, S. H., Hunter, D. J., Hankinson, S. E., Cox, D. G., Hall, P., Wedren, S., Liu, J., Low, Y. L., Bogdanova, N., Schürmann, P., Dörk, T., Tollenaar, R. A. E. M., Jacobi, C. E., Devilee, P., Klijn, J. G. M., Sigurdson, A. J., Doody, M. M., Alexander, B. H., Zhang, J., Cox, A., Brock, I. W., MacPherson, G., Reed, M. W. R., Couch, F. J., Goode, E. L., Olson, J. E., Meijers-Heijboer, H., Van Den Ouweland, A., Uitterlinden, A., Rivadeneira, F., Milne, R. L., Ribas, G., Gonzalez-Neira, A., Benitez, J., Hopper, J. L., McCredie, M., Southey, M., Giles, G., Schroen, C., Justenhoven, C., Brauch, H., Hamann, U., Ko, Y. D., Spurdle, A. B., Beesley, J., Chen, X., Mannermaa, A., Kosma, V. M., Kataja, V., Hartikainen, J., Day, N. E., Cox, D. R., Ponder, B. A. J., Luccarini, C., Conroy, D., Shah, M., Munday, H., Jordan, C., Perkins, B., West, J., Redman, K., Driver, K., Aghmesheh, M., Amor, D., Andrews, L., Antill, Y., Armes, J., Armitage, S., Arnold, L., Balleine, R., Begley, G., Beilby, J., Bennett, I., Bennett, B., Berry, G., Blackburn, A., Brennan, M., Brown, M., Buckley, M., Burke, J., Butow, P., Byron, K., Callen, D., Campbell, I., Clarke, C., Colley, A., Cotton, D., Cui, J., Culling, B., Cummings, M., Dawson, S. J., Dixon, J., Dobrovic, A., Dudding, T., Edkins, T., Eisenbruch, M., Farshid, G., Fawcett, S., Field, M., Firgaira, F., Fleming, J., Forbes, J., Friedlander, M., Gaff, C., Gardner, M., Gattas, M., George, P., Gill, G., Goldblatt, J., Greening, S., Grist, S., Haan, E., Harris, M., Hart, S., Hayward, N., Hopper, J., Humphrey, E., Jenkins, M., Jones, A., Kefford, R., Kirk, J., Kollias, J., Kovalenko, S., Lakhani, S., Leary, J., Lim, J., Lindeman, G., Lipton, L., Lobb, L., Maclurcan, M., Mann, G., Marsh, D., McKay, M., Anne McLachlan, S., Meiser, B., Milne, R., Mitchell, G., Newman, B., O'Loughlin, I., Osborne, R., Peters, L., Phillips, K., Price, M., Reeve, J., Reeve, T., Richards, R., Rinehart, G., Robinson, B., Rudzki, B., Salisbury, E., Sambrook, J., Saunders, C., Scott, C., Scott, E., Scott, R., Seshadri, R., Shelling, A., Spurdle, A., Suthers, G., Taylor, D., Tennant, C., Thorne, H., Townshend, S., Tucker, K., Tyler, J., Venter, D., Visvader, J., Walpole, I., Ward, R., Waring, P., Warner, B., Warren, G., Watson, E., Williams, R., Wilson, J., Winship, I., Young, M. A., Bowtell, D., Bowtell, D., Green, A., DeFazio, A., Gertig, D. & Webb, P., Jun 28 2007, In: Nature. 447, 7148, p. 1087-1093 7 p.

    Research output: Contribution to journalArticlepeer-review

    1826 Scopus citations
  • Genome-Wide Association Study in BRCA1 Mutation Carriers Identifies Novel Loci Associated with Breast and Ovarian Cancer Risk

    Couch, F. J., Wang, X., McGuffog, L., Lee, A., Olswold, C., Kuchenbaecker, K. B., Soucy, P., Fredericksen, Z., Barrowdale, D., Dennis, J., Gaudet, M. M., Dicks, E., Kosel, M., Healey, S., Sinilnikova, O. M., Lee, A., Bacot, F., Vincent, D., Hogervorst, F. B. L., Peock, S., & 241 othersStoppa-Lyonnet, D., Jakubowska, A., Radice, P., Schmutzler, R. K., Domchek, S. M., Piedmonte, M., Singer, C. F., Friedman, E., Thomassen, M., Hansen, T. V. O., Neuhausen, S. L., Szabo, C. I., Blanco, I., Greene, M. H., Karlan, B. Y., Garber, J., Phelan, C. M., Weitzel, J. N., Montagna, M., Olah, E., Andrulis, I. L., Godwin, A. K., Yannoukakos, D., Goldgar, D. E., Caldes, T., Nevanlinna, H., Osorio, A., Terry, M. B., Daly, M. B., van Rensburg, E. J., Hamann, U., Ramus, S. J., Ewart Toland, A., Caligo, M. A., Olopade, O. I., Tung, N., Claes, K., Beattie, M. S., Southey, M. C., Imyanitov, E. N., Tischkowitz, M., Janavicius, R., John, E. M., Kwong, A., Diez, O., Balmaña, J., Barkardottir, R. B., Arun, B. K., Rennert, G., Teo, S. H., Ganz, P. A., Campbell, I., van der Hout, A. H., van Deurzen, C. H. M., Seynaeve, C., Gómez Garcia, E. B., van Leeuwen, F. E., Meijers-Heijboer, H. E. J., Gille, J. J. P., Ausems, M. G. E. M., Blok, M. J., Ligtenberg, M. J. L., Rookus, M. A., Devilee, P., Verhoef, S., van Os, T. A. M., Wijnen, J. T., Frost, D., Ellis, S., Fineberg, E., Platte, R., Evans, D. G., Izatt, L., Eeles, R. A., Adlard, J., Eccles, D. M., Cook, J., Brewer, C., Douglas, F., Hodgson, S., Morrison, P. J., Side, L. E., Donaldson, A., Houghton, C., Rogers, M. T., Dorkins, H., Eason, J., Gregory, H., McCann, E., Murray, A., Calender, A., Hardouin, A., Berthet, P., Delnatte, C., Nogues, C., Lasset, C., Houdayer, C., Leroux, D., Rouleau, E., Prieur, F., Damiola, F., Sobol, H., Coupier, I., Venat-Bouvet, L., Castera, L., Gauthier-Villars, M., Léoné, M., Pujol, P., Mazoyer, S., Bignon, Y. J., Złowocka-Perłowska, E., Gronwald, J., Lubinski, J., Durda, K., Jaworska, K., Huzarski, T., Spurdle, A. B., Peissel, B., Bonanni, B., Melloni, G., Ottini, L., Papi, L., Varesco, L., Tibiletti, M. G., Peterlongo, P., Volorio, S., Manoukian, S., Pensotti, V., Arnold, N., Engel, C., Deissler, H., Gadzicki, D., Gehrig, A., Kast, K., Rhiem, K., Meindl, A., Niederacher, D., Ditsch, N., Plendl, H., Preisler-Adams, S., Engert, S., Sutter, C., Varon-Mateeva, R., Wappenschmidt, B., Weber, B. H. F., Arver, B., Stenmark-Askmalm, M., Loman, N., Rosenquist, R., Einbeigi, Z., Nathanson, K. L., Rebbeck, T. R., Blank, S. V., Cohn, D. E., Rodriguez, G. C., Small, L., Friedlander, M., Bae-Jump, V. L., Fink-Retter, A., Rappaport, C., Gschwantler-Kaulich, D., Pfeiler, G., Tea, M. K., Lindor, N. M., Kaufman, B., Shimon Paluch, S., Laitman, Y., Skytte, A. B., Gerdes, A. M., Pedersen, I. S., Moeller, S. T., Kruse, T. A., Jensen, U. B., Vijai, J., Sarrel, K., Robson, M., Kauff, N., Mulligan, A. M., Glendon, G., Ozcelik, H., Ejlertsen, B., Nielsen, F. C., Jønson, L., Andersen, M. K., Ding, Y. C., Steele, L., Foretova, L., Teulé, A., Lazaro, C., Brunet, J., Pujana, M. A., Mai, P. L., Loud, J. T., Walsh, C., Lester, J., Orsulic, S., Narod, S. A., Herzog, J., Sand, S. R., Tognazzo, S., Agata, S., Vaszko, T., Weaver, J., Stavropoulou, A. V., Buys, S. S., Romero, A., de la Hoya, M., Aittomäki, K., Muranen, T. A., Duran, M., Chung, W. K., Lasa, A., Dorfling, C. M., Miron, A., Benitez, J., Senter, L., Huo, D., Chan, S. B., Sokolenko, A. P., Chiquette, J., Tihomirova, L., Friebel, T. M., Agnarsson, B. A., Lu, K. H., Lejbkowicz, F., James, P. A., Hall, P., Dunning, A. M., Tessier, D., Cunningham, J., Slager, S. L., Wang, C., Hart, S., Stevens, K., Simard, J., Pastinen, T., Pankratz, V. S., Offit, K., Easton, D. F., Chenevix-Trench, G. & Antoniou, A. C., 2013, In: PLoS genetics. 9, 3, e1003212.

    Research output: Contribution to journalArticlepeer-review

    195 Scopus citations
  • Genome-wide association study of germline variants and breast cancer-specific mortality

    NBCS Collaborators, Mar 19 2019, In: British journal of cancer. 120, 6, p. 647-657 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    13 Scopus citations
  • Genome-wide interaction analysis of menopausal hormone therapy use and breast cancer risk among 62,370 women

    Wang, X., Kapoor, P. M., Auer, P. L., Dennis, J., Dunning, A. M., Wang, Q., Lush, M., Michailidou, K., Bolla, M. K., Aronson, K. J., Murphy, R. A., Brooks-Wilson, A., Lee, D. G., Cordina-Duverger, E., Guénel, P., Truong, T., Mulot, C., Teras, L. R., Patel, A. V., Dossus, L., & 60 othersKaaks, R., Hoppe, R., Lo, W. Y., Brüning, T., Hamann, U., Czene, K., Gabrielson, M., Hall, P., Eriksson, M., Jung, A., Becher, H., Couch, F. J., Larson, N. L., Olson, J. E., Ruddy, K. J., Giles, G. G., MacInnis, R. J., Southey, M. C., Le Marchand, L., Wilkens, L. R., Haiman, C. A., Olsson, H., Augustinsson, A., Krüger, U., Wagner, P., Scott, C., Winham, S. J., Vachon, C. M., Perou, C. M., Olshan, A. F., Troester, M. A., Hunter, D. J., Eliassen, H. A., Tamimi, R. M., Brantley, K., Andrulis, I. L., Figueroa, J., Chanock, S. J., Ahearn, T. U., García-Closas, M., Evans, G. D., Newman, W. G., van Veen, E. M., Howell, A., Wolk, A., Håkansson, N., Anton-Culver, H., Ziogas, A., Jones, M. E., Orr, N., Schoemaker, M. J., Swerdlow, A. J., Kitahara, C. M., Linet, M., Prentice, R. L., Easton, D. F., Milne, R. L., Kraft, P., Chang-Claude, J. & Lindström, S., Dec 2022, In: Scientific reports. 12, 1, 6199.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Genome-wide meta-analyses of breast, ovarian, and prostate cancer association studies identify multiple new susceptibility loci shared by at least two cancer types

    Kar, S. P., Beesley, J., Al Olama, A. A., Michailidou, K., Tyrer, J., Kote-Jarai, Z. A., Lawrenson, K., Lindstrom, S., Ramus, S. J., Thompson, D. J., Kibel, A. S., Dansonka-Mieszkowska, A., Michael, A., Dieffenbach, A. K., Gentry-Maharaj, A., Whittemore, A. S., Wolk, A., Monteiro, A., Peixoto, A., Kierzek, A., & 203 othersCox, A., Rudolph, A., Gonzalez-Neira, A., Wu, A. H., Lindblom, A., Swerdlow, A., Ziogas, A., Ekici, A. B., Burwinkel, B., Karlan, B. Y., Nordestgaard, B. G., Blomqvist, C., Phelan, C., McLean, C., Pearce, C. L., Vachon, C., Cybulski, C., Slavov, C., Stegmaier, C., Maier, C., Ambrosone, C. B., Hogdall, C. K., Teerlink, C. C., Kang, D., Tessier, D. C., Schaid, D. J., Stram, D. O., Cramer, D. W., Neal, D. E., Eccles, D., Flesch-Janys, D., Velez Edwards, D. R., Wokozorczyk, D., Levine, D. A., Yannoukakos, D., Sawyer, E. J., Bandera, E. V., Poole, E. M., Goode, E. L., Khusnutdinova, E., Hogdall, E., Song, F., Bruinsma, F., Heitz, F., Modugno, F., Hamdy, F. C., Wiklund, F., Giles, G. G., Olsson, H., Wildiers, H., Ulmer, H. U., Pandha, H., Risch, H. A., Darabi, H., Salvesen, H. B., Nevanlinna, H., Gronberg, H., Brenner, H., Brauch, H., Anton-Culver, H., Song, H., Lim, H. Y., McNeish, I., Campbell, I., Vergote, I., Gronwald, J., Lubiński, J., Stanford, J. L., Benitez, J., Doherty, J. A., Permuth, J. B., Chang-Claude, J., Donovan, J. L., Dennis, J., Schildkraut, J. M., Schleutker, J., Hopper, J. L., Kupryjanczyk, J., Park, J. Y., Figueroa, J., Clements, J. A., Knight, J. A., Peto, J., Cunningham, J. M., Pow-Sang, J., Batra, J., Czene, K., Lu, K. H., Herkommer, K., Khaw, K. T., Matsuo, K., Muir, K., Offitt, K., Chen, K., Moysich, K. B., Aittomaki, K., Odunsi, K., Kiemeney, L. A., Massuger, L. F. A. G., Fitzgerald, L. M., Cook, L. S., Cannon-Albright, L., Hooning, M. J., Pike, M. C., Bolla, M. K., Luedeke, M., Teixeira, M. R., Goodman, M. T., Schmidt, M. K., Riggan, M., Aly, M., Rossing, M. A., Beckmann, M. W., Moisse, M., Sanderson, M., Southey, M. C., Jones, M., Lush, M., Hildebrandt, M. A. T., Hou, M. F., Schoemaker, M. J., Garcia-Closas, M., Bogdanova, N., Rahman, N., Le, N. D., Orr, N., Wentzensen, N., Pashayan, N., Peterlongo, P., Guenel, P., Brennan, P., Paulo, P., Webb, P. M., Broberg, P., Fasching, P. A., Devilee, P., Wang, Q., Cai, Q., Li, Q., Kaneva, R., Butzow, R., Kopperud, R. K., Schmutzler, R. K., Stephenson, R. A., Macinnis, R. J., Hoover, R. N., Winqvist, R., Ness, R., Milne, R. L., Travis, R. C., Benlloch, S., Olson, S. H., McDonnell, S. K., Tworoger, S. S., Maia, S., Berndt, S., Lee, S. C., Teo, S. H., Thibodeau, S. N., Bojesen, S. E., Gapstur, S. M., Kjar, S. K., Pejovic, T., Tammela, T. L. J., Dork, T., Bruning, T., Wahlfors, T., Key, T. J., Edwards, T. L., Menon, U., Hamann, U., Mitev, V., Kosma, V. M., Setiawan, V. W., Kristensen, V., Arndt, V., Vogel, W., Zheng, W., Sieh, W., Blot, W. J., Kluzniak, W., Shu, X. O., Gao, Y. T., Schumacher, F., Freedman, M. L., Berchuck, A., Dunning, A. M., Simard, J., Haiman, C. A., Spurdle, A., Sellers, T. A., Hunter, D. J., Henderson, B. E., Kraft, P., Chanock, S. J., Couch, F. J., Hall, P., Gayther, S. A., Easton, D. F., Chenevix-Trench, G., Eeles, R., Pharoah, P. D. P. & Lambrechts, D., Sep 1 2016, In: Cancer discovery. 6, 9, p. 1052-1067 16 p.

    Research output: Contribution to journalArticlepeer-review

    79 Scopus citations
  • Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

    Day, F. R., Thompson, D. J., Helgason, H., Chasman, D. I., Finucane, H., Sulem, P., Ruth, K. S., Whalen, S., Sarkar, A. K., Albrecht, E., Altmaier, E., Amini, M., Barbieri, C. M., Boutin, T., Campbell, A., Demerath, E., Giri, A., He, C., Hottenga, J. J., Karlsson, R., & 196 othersKolcic, I., Loh, P. R., Lunetta, K. L., Mangino, M., Marco, B., McMahon, G., Medland, S. E., Nolte, I. M., Noordam, R., Nutile, T., Paternoster, L., Perjakova, N., Porcu, E., Rose, L. M., Schraut, K. E., Segrè, A. V., Smith, A. V., Stolk, L., Teumer, A., Andrulis, I. L., Bandinelli, S., Beckmann, M. W., Benitez, J., Bergmann, S., Bochud, M., Boerwinkle, E., Bojesen, S. E., Bolla, M. K., Brand, J. S., Brauch, H., Brenner, H., Broer, L., Brüning, T., Buring, J. E., Campbell, H., Catamo, E., Chanock, S., Chenevix-Trench, G., Corre, T., Couch, F. J., Cousminer, D. L., Cox, A., Crisponi, L., Czene, K., Davey Smith, G., De Geus, E. J. C. N., De Mutsert, R., De Vivo, I., Dennis, J., Devilee, P., Dos-Santos-Silva, I., Dunning, A. M., Eriksson, J. G., Fasching, P. A., Fernández-Rhodes, L., Ferrucci, L., Flesch-Janys, D., Franke, L., Gabrielson, M., Gandin, I., Giles, G. G., Grallert, H., Gudbjartsson, D. F., Guénel, P., Hall, P., Hallberg, E., Hamann, U., Harris, T. B., Hartman, C. A., Heiss, G., Hooning, M. J., Hopper, J. L., Hu, F., Hunter, D. J., Ikram, M. A., Im, H. K., Järvelin, M. R., Joshi, P. K., Karasik, D., Kellis, M., Kutalik, Z., Lachance, G., Lambrechts, D., Langenberg, C., Launer, L. J., Laven, J. S. E., Lenarduzzi, S., Li, J., Lind, P. A., Lindstrom, S., Liu, Y., Luan, JA., Mägi, R., Mannermaa, A., Mbarek, H., McCarthy, M. I., Meisinger, C., Meitinger, T., Menni, C., Metspalu, A., Michailidou, K., Milani, L., Milne, R. L., Montgomery, G. W., Mulligan, A. M., Nalls, M. A., Navarro, P., Nevanlinna, H., Nyholt, D. R., Oldehinkel, A. J., O'Mara, T. A., Padmanabhan, S., Palotie, A., Pedersen, N., Peters, A., Peto, J., Pharoah, P. D. P., Pouta, A., Radice, P., Rahman, I., Ring, S. M., Robino, A., Rosendaal, F. R., Rudan, I., Rueedi, R., Ruggiero, D., Sala, C. F., Schmidt, M. K., Scott, R. A., Shah, M., Sorice, R., Southey, M. C., Sovio, U., Stampfer, M., Steri, M., Strauch, K., Tanaka, T., Tikkanen, E., Timpson, N. J., Traglia, M., Truong, T., Tyrer, J. P., Uitterlinden, A. G., Edwards, D. R. V., Vitart, V., Völker, U., Vollenweider, P., Wang, Q., Widen, E., Van Dijk, K. W., Willemsen, G., Winqvist, R., Wolffenbuttel, B. H. R., Zhao, J. H., Zoledziewska, M., Zygmunt, M., Alizadeh, B. Z., Boomsma, D. I., Ciullo, M., Cucca, F., Esko, T., Franceschini, N., Gieger, C., Gudnason, V., Hayward, C., Kraft, P., Lawlor, D. A., Magnusson, P. K. E., Martin, N. G., Mook-Kanamori, D. O., Nohr, E. A., Polasek, O., Porteous, D., Price, A. L., Ridker, P. M., Snieder, H., Spector, T. D., Stöckl, D., Toniolo, D., Ulivi, S., Visser, J. A., Völzke, H., Wareham, N. J., Wilson, J. F., Spurdle, A. B., Thorsteindottir, U., Pollard, K. S., Easton, D. F., Tung, J. Y., Chang-Claude, J., Hinds, D., Murray, A., Murabito, J. M., Stefansson, K., Ong, K. K. & Perry, J. R. B., Jun 1 2017, In: Nature Genetics. 49, 6, p. 834-841 8 p.

    Research output: Contribution to journalArticlepeer-review

    184 Scopus citations
  • Germline BRCA1/2 mutations and severe haematological toxicities in patients with breast cancer treated with neoadjuvant chemotherapy

    Furlanetto, J., Möbus, V., Schneeweiss, A., Rhiem, K., Tesch, H., Blohmer, J. U., Lübbe, K., Untch, M., Salat, C., Huober, J., Klare, P., Schmutzler, R., Couch, F. J., Lederer, B., Gerber, B., Zahm, D. M., Bauerfeind, I., Nekljudova, V., Hanusch, C., Jackisch, C., & 4 othersLink, T., Hahnen, E., Loibl, S. & Fasching, P. A., Mar 2021, In: European Journal of Cancer. 145, p. 44-52 9 p.

    Research output: Contribution to journalArticlepeer-review

  • Germ line fanconi anemia complementation group C mutations and pancreatic cancer

    Couch, F. J., Johnson, M. R., Rabe, K., Boardman, L., McWilliams, R., De Andrade, M. & Petersen, G., Jan 15 2005, In: Cancer research. 65, 2, p. 383-386 4 p.

    Research output: Contribution to journalArticlepeer-review

    110 Scopus citations
  • Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk

    NBCS Collaborators, OSBREAC & ABCTB Investigators, Dec 1 2020, In: Scientific reports. 10, 1, 9688.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Germline Pathogenic Variants in Cancer Predisposition Genes among Women with Invasive Lobular Carcinoma of the Breast

    Yadav, S., Hu, C., Nathanson, K. L., Weitzel, J. N., Goldgar, D. E., Kraft, P., Gnanaolivu, R. D., Na, J., Huang, H., Boddicker, N. J., Larson, N., Gaoc, C., Yao, S., Weinberg, C., Vachon, C. M., Trentham-Dietz, A., Taylor, J. A., Sandler, D. R., Patel, A., Palmer, J. R., & 22 othersOlson, J. E., Neuhausen, S., Martinez, E., Lindstrom, S., Lacey, J. V., Kurian, A. W., John, E. M., Haiman, C., Bernstein, L., Auer, P. W., Anton-Culver, H., Ambrosone, C. B., Karam, R., Chao, E., Yussuf, A., Pesaran, T., Dolinsky, J. S., Hart, S. N., LaDuca, H., Polley, E. C., Domchek, S. M. & Couch, F. J., Dec 10 2021, In: Journal of Clinical Oncology. 39, 35, p. 3918-3926 9 p.

    Research output: Contribution to journalArticlepeer-review

  • Germline variants and breast cancer survival in patients with distant metastases at primary breast cancer diagnosis

    kConFab/AOCS Investigators, Dec 2021, In: Scientific reports. 11, 1, 19787.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Germline variation in ADAMTSL1 is associated with prognosis following breast cancer treatment in young women

    Kadalayil, L., Khan, S., Nevanlinna, H., Fasching, P. A., Couch, F. J., Hopper, J. L., Liu, J., Maishman, T., Durcan, L., Gerty, S., Blomqvist, C., Rack, B., Janni, W., Collins, A., Eccles, D. & Tapper, W., Dec 1 2017, In: Nature communications. 8, 1, 1632.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    11 Scopus citations
  • Haplotype and phenotype analysis of six recurrent BRCA1 mutations in 61 families: Results of an international study

    Neuhausen, S. L., Mazoyer, S., Friedman, L., Stratton, M., Offit, K., Caligo, A., Tomlinson, G., Cannon-Albright, L., Bishop, T., Kelsell, D., Solomon, E., Weber, B., Couch, F., Struewing, J., Tonin, P., Durocher, F., Narod, S., Skolnick, M. H., Lenoir, G., Serova, O., & 5 othersPonder, B., Stoppa-Lyonnet, D., Easton, D., King, M. C. & Goldgar, D. E., 1996, In: American journal of human genetics. 58, 2, p. 271-280 10 p.

    Research output: Contribution to journalArticlepeer-review

    218 Scopus citations
  • Haplotype structure in Ashkenazi Jewish BRCA1 and BRCA2 mutation carriers

    The CONSIT TEAM study, Nov 1 2011, In: Human genetics. 130, 5, p. 685-699 15 p.

    Research output: Contribution to journalArticlepeer-review

    13 Scopus citations
  • Height and body mass index as Modifiers of breast cancer risk in BRCA1/2 mutation carriers: A Mendelian randomization study

    GEMO Study Collaborators, HEBON, EMBRACE, Apr 1 2019, In: Journal of the National Cancer Institute. 111, 4, p. 350-364 15 p.

    Research output: Contribution to journalArticlepeer-review

    7 Scopus citations
  • Height and breast cancer risk: Evidence from prospective studies and mendelian randomization

    Zhang, B., Shu, X. O., Delahanty, R. J., Zeng, C., Michailidou, K., Bolla, M. K., Wang, Q., Dennis, J., Wen, W., Long, J., Li, C., Dunning, A. M., Chang-Claude, J., Shah, M., Perkins, B. J., Czene, K., Darabi, H., Eriksson, M., Bojesen, S. E., Nordestgaard, B. G., & 151 othersNielsen, S. F., Flyger, H., Lambrechts, D., Neven, P., Wildiers, H., Floris, G., Schmidt, M. K., Rookus, M. A., Van Den Hurk, K., De Kort, W. L. A. M., Couch, F. J., Olson, J. E., Hallberg, E., Vachon, C., Rudolph, A., Seibold, P., Flesch-Janys, D., Peto, J., Dos-Santos-Silva, I., Fletcher, O., Johnson, N., Nevanlinna, H., Muranen, T. A., Aittomäki, K., Blomqvist, C., Li, J., Humphreys, K., Brand, J., Guénel, P., Truong, T., Cordina-Duverger, E., Menegaux, F., Burwinkel, B., Marme, F., Yang, R., Surowy, H., Benitez, J., Zamora, M. P., Perez, J. I. A., Cox, A., Cross, S. S., Reed, M. W. R., Andrulis, I. L., Knight, J. A., Glendon, G., Tchatchou, S., Sawyer, E. J., Tomlinson, I., Kerin, M. J., Miller, N., Chenevix-Trench, G., Haiman, C. A., Henderson, B. E., Schumacher, F., Le Marchand, L., Lindblom, A., Margolin, S., Hooning, M. J., Martens, J. W. M., Tilanus-Linthorst, M. M. A., Collée, J. M., Hopper, J. L., Southey, M. C., Tsimiklis, H., Apicella, C., Slager, S., Toland, A. E., Ambrosone, C. B., Yannoukakos, D., Giles, G. G., Milne, R. L., McLean, C., Fasching, P. A., Haeberle, L., Ekici, A. B., Beckmann, M. W., Brenner, H., Dieffenbach, A. K., Arndt, V., Stegmaier, C., Swerdlow, A. J., Ashworth, A., Orr, N., Jones, M., Figueroa, J., Garcia-Closas, M., Brinton, L., Lissowska, J., Dumont, M., Winqvist, R., Pylkäs, K., Jukkola-Vuorinen, A., Grip, M., Brauch, H., Brüning, T., Ko, Y. D., Peterlongo, P., Manoukian, S., Bonanni, B., Radice, P., Bogdanova, N., Antonenkova, N., Dörk, T., Mannermaa, A., Kataja, V., Kosma, V. M., Hartikainen, J. M., Devilee, P., Seynaeve, C., Van Asperen, C. J., Jakubowska, A., Lubiski, J., Jaworska-Bieniek, K., Durda, K., Hamann, U., Torres, D., Schmutzler, R. K., Neuhausen, S. L., Anton-Culver, H., Kristensen, V. N., Grenaker Alnæs, G. I., Pierce, B. L., Kraft, P., Peters, U., Lindstrom, S., Seminara, D., Burgess, S., Ahsan, H., Whittemore, A. S., John, E. M., Gammon, M. D., Malone, K. E., Tessier, D. C., Vincent, D., Bacot, F., Luccarini, C., Baynes, C., Ahmed, S., Maranian, M., Healey, C. S., González-Neira, A., Pita, G., Alonso, M. R., Álvarez, N., Herrero, D., Pharoah, P. D. P., Simard, J., Hall, P., Hunter, D. J., Easton, D. F. & Zheng, W., Nov 2015, In: Journal of the National Cancer Institute. 107, 11

    Research output: Contribution to journalArticlepeer-review

    Open Access
    70 Scopus citations
  • Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics

    Garcia-Closas, M., Hall, P., Nevanlinna, H., Pooley, K., Morrison, J., Richesson, D. A., Bojesen, S. E., Nordestgaard, B. G., Axelsson, C. K., Arias, J. I., Milne, R. L., Ribas, G., González-Neira, A., Benítez, J., Zamora, P., Brauch, H., Justenhoven, C., Hamann, U., Ko, Y. D., Bruening, T., & 91 othersHaas, S., Dörk, T., Schürmann, P., Hillemanns, P., Bogdanova, N., Bremer, M., Karstens, J. H., Fagerholm, R., Aaltonen, K., Aittomäki, K., Von Smitten, K., Blomqvist, C., Mannermaa, A., Uusitupa, M., Eskelinen, M., Tengström, M., Kosma, V. M., Kataja, V., Chenevix-Trench, G., Spurdle, A. B., Beesley, J., Chen, X., Devilee, P., Van Asperen, C. J., Jacobi, C. E., Tollenaar, R. A. E. M., Huijts, P. E. A., Klijn, J. G. M., Chang-Claude, J., Kropp, S., Slanger, T., Flesch-Janys, D., Mutschelknauss, E., Salazar, R., Wang-Gohrke, S., Couch, F., Goode, E. L., Olson, J. E., Vachon, C., Fredericksen, Z. S., Giles, G. G., Baglietto, L., Severi, G., Hopper, J. L., English, D. R., Southey, M. C., Haiman, C. A., Henderson, B. E., Kolonel, L. N., Le Marchand, L., Stram, D. O., Hunter, D. J., Hankinson, S. E., Cox, D. G., Tamimi, R., Kraft, P., Sherman, M. E., Chanock, S. J., Lissowska, J., Brinton, L. A., Peplonska, B., Hooning, M. J., Meijers-Heijboer, H., Collee, J. M., Van Den Ouweland, A., Uitterlinden, A. G., Liu, J., Low, Y. L., Yuqing, L., Humphreys, K., Czene, K., Cox, A., Balasubramanian, S. P., Cross, S. S., Reed, M. W. R., Blows, F., Driver, K., Dunning, A., Tyrer, J., Ponder, B. A. J., Sangrajrang, S., Brennan, P., McKay, J., Odefrey, F., Gabrieau, V., Sigurdson, A., Doody, M., Struewing, J. P., Alexander, B., Easton, D. F. & Pharoah, P. D., Apr 2008, In: PLoS genetics. 4, 4, e1000054.

    Research output: Contribution to journalArticlepeer-review

    279 Scopus citations
  • Heterogeneity of luminal breast cancer characterised by immunohistochemical expression of basal markers

    Sung, H., Garcia-Closas, M., Chang-Claude, J., Blows, F. M., Ali, H. R., Figueroa, J., Nevanlinna, H., Fagerholm, R., Heikkilä, P., Blomqvist, C., Giles, G. G., Milne, R. L., Southey, M. C., McLean, C., Mannermaa, A., Kosma, V. M., Kataja, V., Sironen, R., Couch, F. J., Olson, J. E., & 16 othersHallberg, E., Olswold, C., Cox, A., Cross, S. S., Kraft, P., Tamimi, R. M., Eliassen, A. H., Schmidt, M. K., Bolla, M. K., Wang, Q., Easton, D., Howat, W. J., Coulson, P., Pharoah, P. D. P., Sherman, M. E. & Yang, X. R., Feb 2 2016, In: British journal of cancer. 114, 3, p. 298-304 7 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    6 Scopus citations
  • High-throughput automated scoring of Ki67 in breast cancer tissue microarrays from the Breast Cancer Association Consortium

    Abubakar, M., Howat, W. J., Daley, F., Zabaglo, L., McDuffus, L. A., Blows, F., Coulson, P., Raza Ali, H., Benitez, J., Milne, R., Brenner, H., Stegmaier, C., Mannermaa, A., Chang-Claude, J., Rudolph, A., Sinn, P., Couch, F. J., Tollenaar, R. A. E. M., Devilee, P., Figueroa, J., & 23 othersSherman, M. E., Lissowska, J., Hewitt, S., Eccles, D., Hooning, M. J., Hollestelle, A., Martens, J., HM van Deurzen, C., Investigators, K. C. F., Bolla, M. K., Wang, Q., Jones, M., Schoemaker, M., Broeks, A., van Leeuwen, F. E., Van't Veer, L., Swerdlow, A. J., Orr, N., Dowsett, M., Easton, D., Schmidt, M. K., Pharoah, P. D. & Garcia-Closas, M., Jul 1 2016, In: Journal of Pathology: Clinical Research. 2, 3, p. 138-153 16 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    14 Scopus citations
  • Hi-Plex2: A simple and robust approach to targeted sequencing-based genetic screening

    Hammet, F., Mahmood, K., Green, T. R., Nguyen-Dumont, T., Southey, M. C., Buchanan, D. D., Lonie, A., Nathanson, K. L., Couch, F. J., Pope, B. J. & Park, D. J., 2019, In: BioTechniques. 67, 3, p. 118-122 5 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    5 Scopus citations
  • Hormone replacement therapy after oophorectomy and breast cancer risk among BRCA1 mutation carriers

    Hereditary Breast Cancer Clinical Study Group, Aug 2018, In: JAMA Oncology. 4, 8, p. 1059-1065 7 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    56 Scopus citations
  • Hormone therapy and the risk of breast cancer in BRCA1 mutation carriers

    Eisen, A., Lubinski, J., Gronwald, J., Moller, P., Lynch, H. T., Klijn, J., Kim-Sing, C., Neuhausen, S. L., Gilbert, L., Ghadirian, P., Manoukian, S., Rennert, G., Friedman, E., Isaacs, C., Rosen, E., Rosen, B., Daly, M., Sun, P., Narod, S. A., Olopade, O., & 37 othersCummings, S., Tung, N., Couch, F., Foulkes, W. D., Domchek, S., Stoppa-Lyonnet, D., Gershoni-Baruch, R., Horsman, D., Wagner, T., Saal, H., Warner, E., Meschino, W., Offit, K., Trivedi, A., Robson, M., Osborne, M., Gilchrist, D., Eng, C., Weitzel, J., McKinnon, W., Wood, M., Maugard, C., Pasini, B., Ainsworth, P., Sweet, K., Pasche, B., Fallen, T., Karlan, B., Kurz, R. N., Armel, S., Tulman, A., Lemire, E., Mclennan, J., Evans, G., Byrski, T., Huzarski, T. & Shulman, L., Oct 2008, In: Journal of the National Cancer Institute. 100, 19, p. 1361-1367 7 p.

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    147 Scopus citations
  • Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk

    The GENICA Network, The GENICA Network, The GENICA Network, The GENICA Network, The GENICA Network, The GENICA Network, The GENICA Network, KConFab investigators, Australian Ovarian Cancer Study Group, The Breast and Ovarian Cancer Susceptibility (BOCS) Study, Australian Ovarian Cancer Study Group & The GENICA Network, Jan 1 2015, In: Human molecular genetics. 24, 1, p. 285-298 14 p.

    Research output: Contribution to journalArticlepeer-review

    31 Scopus citations
  • Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31

    Permuth-Wey, J., Lawrenson, K., Shen, H. C., Velkova, A., Tyrer, J. P., Chen, Z., Lin, H. Y., Ann Chen, Y., Tsai, Y. Y., Qu, X., Ramus, S. J., Karevan, R., Lee, J., Lee, N., Larson, M. C., Aben, K. K., Anton-Culver, H., Antonenkova, N., Antoniou, A. C., Armasu, S. M., & 158 othersBacot, F., Baglietto, L., Bandera, E. V., Barnholtz-Sloan, J., Beckmann, M. W., Birrer, M. J., Bloom, G., Bogdanova, N., Brinton, L. A., Brooks-Wilson, A., Brown, R., Butzow, R., Cai, Q., Campbell, I., Chang-Claude, J., Chanock, S., Chenevix-Trench, G., Cheng, J. Q., Cicek, M. S., Coetzee, G. A., Cook, L. S., Couch, F. J., Cramer, D. W., Cunningham, J. M., Dansonka-Mieszkowska, A., Despierre, E., Doherty, J. A., Dörk, T., Du Bois, A., Dürst, M., Easton, D. F., Eccles, D., Edwards, R., Ekici, A. B., Fasching, P. A., Fenstermacher, D. A., Flanagan, J. M., Garcia-Closas, M., Gentry-Maharaj, A., Giles, G. G., Glasspool, R. M., Gonzalez-Bosquet, J., Goodman, M. T., Gore, M., Górski, B., Gronwald, J., Hall, P., Halle, M. K., Harter, P., Heitz, F., Hillemanns, P., Hoatlin, M., Høgdall, C. K., Høgdall, E., Hosono, S., Jakubowska, A., Jensen, A., Jim, H., Kalli, K. R., Karlan, B. Y., Kaye, S. B., Kelemen, L. E., Kiemeney, L. A., Kikkawa, F., Konecny, G. E., Krakstad, C., Krüger Kjaer, S., Kupryjanczyk, J., Lambrechts, D., Lambrechts, S., Lancaster, J. M., Le, N. D., Leminen, A., Levine, D. A., Liang, D., Kiong Lim, B., Lin, J., Lissowska, J., Lu, K. H., Lubiński, J., Lurie, G., Massuger, L. F. A. G., Matsuo, K., McGuire, V., McLaughlin, J. R., Menon, U., Modugno, F., Moysich, K. B., Nakanishi, T., Narod, S. A., Nedergaard, L., Ness, R. B., Nevanlinna, H., Nickels, S., Noushmehr, H., Odunsi, K., Olson, S. H., Orlow, I., Paul, J., Pearce, C. L., Pejovic, T., Pelttari, L. M., Pike, M. C., Poole, E. M., Raska, P., Renner, S. P., Risch, H. A., Rodriguez-Rodriguez, L., Anne Rossing, M., Rudolph, A., Runnebaum, I. B., Rzepecka, I. K., Salvesen, H. B., Schwaab, I., Severi, G., Shridhar, V., Shu, X. O., Shvetsov, Y. B., Sieh, W., Song, H., Southey, M. C., Spiewankiewicz, B., Stram, D., Sutphen, R., Teo, S. H., Terry, K. L., Tessier, D. C., Thompson, P. J., Tworoger, S. S., Van Altena, A. M., Vergote, I., Vierkant, R. A., Vincent, D., Vitonis, A. F., Wang-Gohrke, S., Palmieri Weber, R., Wentzensen, N., Whittemore, A. S., Wik, E., Wilkens, L. R., Winterhoff, B., Ling Woo, Y., Wu, A. H., Xiang, Y. B., Yang, H. P., Zheng, W., Ziogas, A., Zulkifli, F., Phelan, C. M., Iversen, E., Schildkraut, J. M., Berchuck, A., Fridley, B. L., Goode, E. L., Pharoah, P. D. P., Monteiro, A. N. A., Sellers, T. A. & Gayther, S. A., 2013, In: Nature communications. 4, 1627.

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    79 Scopus citations
  • Identification and validation of an anthracycline/cyclophosphamide-based chemotherapy response assay in breast cancer

    Mulligan, J. M., Hill, L. A., Deharo, S., Irwin, G., Boyle, D., Keating, K. E., Raji, O. Y., McDyer, F. A., O'Brien, E., Bylesjo, M., Quinn, J. E., Lindor, N. M., Mullan, P. B., James, C. R., Walker, S. M., Kerr, P., James, J., Davison, T. S., Proutski, V., Salto-Tellez, M., & 4 othersJohnston, P. G., Couch, F. J., Paul Harkin, D. & Kennedy, R. D., Jan 2014, In: Journal of the National Cancer Institute. 106, 1

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    62 Scopus citations
  • Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

    AOCS study group, EMBRACE Study, OPAL study group, KConFab investigators, GEMO Study Collaborators & HEBON Study, May 1 2017, In: Nature Genetics. 49, 5, p. 680-691 12 p.

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  • Identification of a BRCA2-Specific Modifier Locus at 6p24 Related to Breast Cancer Risk

    Gaudet, M. M., Kuchenbaecker, K. B., Vijai, J., Klein, R. J., Kirchhoff, T., McGuffog, L., Barrowdale, D., Dunning, A. M., Lee, A., Dennis, J., Healey, S., Dicks, E., Soucy, P., Sinilnikova, O. M., Pankratz, V. S., Wang, X., Eldridge, R. C., Tessier, D. C., Vincent, D., Bacot, F., & 287 othersHogervorst, F. B. L., Peock, S., Stoppa-Lyonnet, D., Coulet, F., Colas, C., Soubrier, F., Peterlongo, P., Schmutzler, R. K., Nathanson, K. L., Piedmonte, M., Singer, C. F., Thomassen, M., Sokolowska, J., Bronner, M., Hansen, T. V. O., Neuhausen, S. L., Blanco, I., Greene, M. H., Garber, J., Weitzel, J. N., Andrulis, I. L., Goldgar, D. E., D'Andrea, E., Caldes, T., Nevanlinna, H., Osorio, A., van Rensburg, E. J., Arason, A., Rennert, G., van den Ouweland, A. M. W., van der Hout, A. H., Kets, C. M., Aalfs, C. M., Wijnen, J. T., Ausems, M. G. E. M., Frost, D., Ellis, S., Fineberg, E., Platte, R., Evans, D. G., Jacobs, C., Adlard, J., Tischkowitz, M., Porteous, M. E., Damiola, F., Golmard, L., Barjhoux, L., Longy, M., Belotti, M., Ferrer, S. F., Mazoyer, S., Spurdle, A. B., Manoukian, S., Barile, M., Genuardi, M., Arnold, N., Meindl, A., Sutter, C., Wappenschmidt, B., Domchek, S. M., Pfeiler, G., Friedman, E., Jensen, U. B., Robson, M., Shah, S., Lazaro, C., Mai, P. L., Benitez, J., Southey, M. C., Schmidt, M. K., Fasching, P. A., Peto, J., Humphreys, M. K., Wang, Q., Michailidou, K., Sawyer, E. J., Burwinkel, B., Guénel, P., Bojesen, S. E., Milne, R. L., Brenner, H., Lochmann, M., Brauch, H., Ko, Y. D., Baisch, C., Fischer, H. P., Bruening, T., Pesch, B., Rabstein, S., Spickenheuer, A., Aittomäki, K., Dörk, T., Margolin, S., Mannermaa, A., Lambrechts, D., Chang-Claude, J., Radice, P., Giles, G. G., Haiman, C. A., Winqvist, R., Devillee, P., García-Closas, M., Schoof, N., Hooning, M. J., Cox, A., Pharoah, P. D. P., Jakubowska, A., Orr, N., González-Neira, A., Pita, G., Alonso, M. R., Hall, P., Couch, F. J., Simard, J., Altshuler, D., Easton, D. F., Chenevix-Trench, G., Antoniou, A. C., Offit, K., Rookus, M. A., van Leeuwen, F. E., Verhoef, S., de Lange, J. L., Collée, J. M., Seynaeve, C., van Deurzen, C. H. M., van Asperen, C. J., Tollenaar, R. A., Devilee, P., van Cronenburg, T. C. T. E. F., Mensenkamp, A. R., van der Luijt, R. B., van Os, T. A. M., Gille, J. J. P., Waisfisz, Q., Meijers-Heijboer, H. E. J., Gómez-Garcia, E. B., Blok, M. J., Oosterwijk, J. C., Mourits, M. J., de Bock, G. H., Vasen, H. F., Miedzybrodzka, Z., Gregory, H., Morrison, P., Jeffers, L., Cole, T., Ong, K. R., Hoffman, J., Donaldson, A., James, M., Paterson, J., Taylor, A., Murray, A., Rogers, M. T., McCann, E., Kennedy, M. J., Barton, D., Porteous, M., Drummond, S., Brewer, C., Kivuva, E., Searle, A., Goodman, S., Hill, K., Davidson, R., Murday, V., Bradshaw, N., Snadden, L., Longmuir, M., Watt, C., Gibson, S., Haque, E., Tobias, E., Duncan, A., Izatt, L., Langman, C., Brady, A., Dorkins, H., Melville, A., Randhawa, K., Barwell, J., Serra-Feliu, G., Ellis, I., Houghton, C., Lalloo, F., Taylor, J., Side, L., Male, A., Berlin, C., Eason, J., Douglas, F., Claber, O., Collier, R., Jobson, I., Walker, L., McLeod, D., Durell, S., Stayner, B., Eeles, R. A., Shanley, S., Rahman, N., Houlston, R., Bancroft, E., Page, E., Ardern-Jones, A., Kohut, K., Wiggins, J., Castro, E., Killick, E., Martin, S., Rea, G., Kulkarni, A., Cook, J., Quarrell, O., Bardsley, C., Hodgson, S., Goff, S., Brice, G., Winchester, L., Eddy, C., Tripathi, V., Attard, V., Lehmann, A., Eccles, D., Lucassen, A., Crawford, G., McBride, D., Smalley, S., Sinilnikova, O., Verny-Pierre, C., Giraud, S., Léone, M., Gauthier-Villars, M., Buecher, B., Houdayer, C., Moncoutier, V., Tirapo, C., de Pauw, A., Bressac-de-Paillerets, B., Caron, O., Bignon, Y. J., Uhrhammer, N., Lasset, C., Bonadona, V., Handallou, S., Hardouin, A., Berthet, P., Sobol, H., Bourdon, V., Noguchi, T., Remenieras, A., Coupier, I., Pujol, P., Peyrat, J. P., Fournier, J., Révillion, F., Vennin, P., Adenis, C., Rouleau, E., Lidereau, R., Demange, L., Nogues, C., Muller, D., Fricker, J. P., Barouk-Simonet, E., Bonnet, F., Bubien, V., Sevenet, N., Toulas, C., Guimbaud, R., Gladieff, L., Feillel, V., Dreyfus, H., Rebischung, C., Peysselon, M., Coron, F., Faivre, L., Prieur, F., Lebrun, M., Kientz, C., Frénay, M., Vénat-Bouvet, L., Delnatte, C., Mortemousque, I., Lynch, H. T. & Snyder, C. L., 2013, In: PLoS genetics. 9, 3, e1003173.

    Research output: Contribution to journalArticlepeer-review

    84 Scopus citations
  • Identification of a novel percent mammographic density locus at 12q24

    Stevens, K. N., Lindstrom, S., Scott, C. G., Thompson, D., Sellers, T. A., Wang, X., Wang, A., Atkinson, E., Rider, D. N., Eckel-passow, J. E., Varghese, J. S., Audley, T., Brown, J., Leyland, J., Luben, R. N., Warren, R. M. L., Loos, R. J. F., Wareham, N. J., Li, J., Hall, P., & 34 othersLiu, J., Eriksson, L., Czene, K., Olson, J. E., Shane pankratz, V., Fredericksen, Z., Diasio, R. B., Lee, A. M., Heit, J. A., Deandrade, M., Goode, E. L., Vierkant, R. A., Cunningham, J. M., Armasu, S. M., Weinshilboum, R., Fridley, B. L., Batzler, A., Ingle, J. N., Boyd, N. F., Paterson, A. D., Rommens, J., Martin, L. J., Hopper, J. L., Southey, M. C., Stone, J., Apicella, C., Kraft, P., Hankinson, S. E., Hazra, A., Hunter, D. J., Easton, D. F., Couch, F. J., Tamimi, R. M. & Vachon, C. M., Jul 2012, In: Human molecular genetics. 21, 14, p. 3299-3305 7 p., dds158.

    Research output: Contribution to journalArticlepeer-review

    26 Scopus citations
  • Identification of a pyruvate-to-lactate signature in pancreatic intraductal papillary mucinous neoplasms

    Penheiter, A. R., Deelchand, D. K., Kittelson, E., Damgard, S. E., Murphy, S. J., O'Brien, D. R., Bamlet, W. R., Passow, M. R., Smyrk, T. C., Couch, F. J., Vasmatzis, G., Port, J. D., Marjańska, M. & Carlson, S. K., Jan 2018, In: Pancreatology. 18, 1, p. 46-53 8 p.

    Research output: Contribution to journalArticlepeer-review

    6 Scopus citations
  • Identification of BRCA1 missense substitutions that confer partial functional activity: Potential moderate risk variants?

    Lovelock, P. K., Spurdle, A. B., Mok, M. T. S., Farrugia, D. J., Lakhani, S. R., Healey, S., Arnold, S., Buchanan, D., Investigators, K. C. F., Couch, F. J., Henderson, B. R., Goldgar, D. E., Tavtigian, S. V., Chenevix-Trench, G. & Brown, M. A., Nov 26 2007, In: Breast Cancer Research. 9, 6, R82.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    42 Scopus citations
  • Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer

    Couch, F. J., Kuchenbaecker, K. B., Michailidou, K., Mendoza-Fandino, G. A., Nord, S., Lilyquist, J., Olswold, C., Hallberg, E., Agata, S., Ahsan, H., Aittomäki, K., Ambrosone, C., Andrulis, I. L., Anton-Culver, H., Arndt, V., Arun, B. K., Arver, B., Barile, M., Barkardottir, R. B., Barrowdale, D., & 229 othersBeckmann, L., Beckmann, M. W., Benitez, J., Blank, S. V., Blomqvist, C., Bogdanova, N. V., Bojesen, S. E., Bolla, M. K., Bonanni, B., Brauch, H., Brenner, H., Burwinkel, B., Buys, S. S., Caldes, T., Caligo, M. A., Canzian, F., Carpenter, J., Chang-Claude, J., Chanock, S. J., Chung, W. K., Claes, K. B. M., Cox, A., Cross, S. S., Cunningham, J. M., Czene, K., Daly, M. B., Damiola, F., Darabi, H., De La Hoya, M., Devilee, P., Diez, O., Ding, Y. C., Dolcetti, R., Domchek, S. M., Dorfling, C. M., Dos-Santos-Silva, I., Dumont, M., Dunning, A. M., Eccles, D. M., Ehrencrona, H., Ekici, A. B., Eliassen, H., Ellis, S., Fasching, P. A., Figueroa, J., Flesch-Janys, D., Försti, A., Fostira, F., Foulkes, W. D., Friebel, T., Friedman, E., Frost, D., Gabrielson, M., Gammon, M. D., Ganz, P. A., Gapstur, S. M., Garber, J., Gaudet, M. M., Gayther, S. A., Gerdes, A. M., Ghoussaini, M., Giles, G. G., Glendon, G., Godwin, A. K., Goldberg, M. S., Goldgar, D. E., González-Neira, A., Greene, M. H., Gronwald, J., Guénel, P., Gunter, M., Haeberle, L., Haiman, C. A., Hamann, U., Hansen, T. V. O., Hart, S., Healey, S., Heikkinen, T., Henderson, B. E., Herzog, J., Hogervorst, F. B. L., Hollestelle, A., Hooning, M. J., Hoover, R. N., Hopper, J. L., Humphreys, K., Hunter, D. J., Huzarski, T., Imyanitov, E. N., Isaacs, C., Jakubowska, A., James, P., Janavicius, R., Jensen, U. B., John, E. M., Jones, M., Kabisch, M., Kar, S., Karlan, B. Y., Khan, S., Khaw, K. T., Kibriya, M. G., Knight, J. A., Ko, Y. D., Konstantopoulou, I., Kosma, V. M., Kristensen, V., Kwong, A., Laitman, Y., Lambrechts, D., Lazaro, C., Lee, E., Le Marchand, L., Lester, J., Lindblom, A., Lindor, N., Lindstrom, S., Liu, J., Long, J., Lubinski, J., Mai, P. L., Makalic, E., Malone, K. E., Mannermaa, A., Manoukian, S., Margolin, S., Marme, F., Martens, J. W. M., Mcguffog, L., Meindl, A., Miller, A., Milne, R. L., Miron, P., Montagna, M., Mazoyer, S., Mulligan, A. M., Muranen, T. A., Nathanson, K. L., Neuhausen, S. L., Nevanlinna, H., Nordestgaard, B. G., Nussbaum, R. L., Offit, K., Olah, E., Olopade, O. I., Olson, J. E., Osorio, A., Park, S. K., Peeters, P. H., Peissel, B., Peterlongo, P., Peto, J., Phelan, C. M., Pilarski, R., Poppe, B., Pylkäs, K., Radice, P., Rahman, N., Rantala, J., Rappaport, C., Rennert, G., Richardson, A., Robson, M., Romieu, I., Rudolph, A., Rutgers, E. J., Sanchez, M. J., Santella, R. M., Sawyer, E. J., Schmidt, D. F., Schmidt, M. K., Schmutzler, R. K., Schumacher, F., Scott, R., Senter, L., Sharma, P., Simard, J., Singer, C. F., Sinilnikova, O. M., Soucy, P., Southey, M., Steinemann, D., Stenmark-Askmalm, M., Stoppa-Lyonnet, D., Swerdlow, A., Szabo, C. I., Tamimi, R., Tapper, W., Teixeira, M. R., Teo, S. H., Terry, M. B., Thomassen, M., Thompson, D., Tihomirova, L., Toland, A. E., Tollenaar, R. A. E. M., Tomlinson, I., Truong, T., Tsimiklis, H., Teulé, A., Tumino, R., Tung, N., Turnbull, C., Ursin, G., Van Deurzen, C. H. M., Van Rensburg, E. J., Varon-Mateeva, R., Wang, Z., Wang-Gohrke, S., Weiderpass, E., Weitzel, J. N., Whittemore, A., Wildiers, H., Winqvist, R., Yang, X. R., Yannoukakos, D., Yao, S., Zamora, M. P., Zheng, W., Hall, P., Kraft, P., Vachon, C., Slager, S., Chenevix-Trench, G., Pharoah, P. D. P., Monteiro, A. A. N., García-Closas, M., Easton, D. F. & Antoniou, A. C., Apr 27 2016, In: Nature communications. 7, 11375.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    55 Scopus citations
  • Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus

    on behalf of HEBON, on behalf of KConFab, AOCS Investigators, on behalf of EMBRACE & behalf of GEMO Study Collaborators, Jun 21 2016, In: Breast Cancer Research. 18, 1, 64.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    18 Scopus citations
  • Identification of inherited genetic variations influencing prognosis in early-onset breast cancer

    Rafiq, S., Tapper, W., Collins, A., Khan, S., Politopoulos, I., Gerty, S., Blomqvist, C., Couch, F. J., Nevanlinna, H., Liu, J. & Eccles, D., Mar 15 2013, In: Cancer research. 73, 6, p. 1883-1891 9 p.

    Research output: Contribution to journalArticlepeer-review

    32 Scopus citations
  • Identification of new genetic susceptibility loci for breast cancer through consideration of gene-environment interactions

    Schoeps, A., Rudolph, A., Seibold, P., Dunning, A. M., Milne, R. L., Bojesen, S. E., Swerdlow, A., Andrulis, I., Brenner, H., Behrens, S., Orr, N., Jones, M., Ashworth, A., Li, J., Cramp, H., Connley, D., Czene, K., Darabi, H., Chanock, S. J., Lissowska, J., & 61 othersFigueroa, J. D., Knight, J., Glendon, G., Mulligan, A. M., Dumont, M., Severi, G., Baglietto, L., Olson, J., Vachon, C., Purrington, K., Moisse, M., Neven, P., Wildiers, H., Spurdle, A., Kosma, V. M., Kataja, V., Hartikainen, J. M., Hamann, U., Ko, Y. D., Dieffenbach, A. K., Arndt, V., Stegmaier, C., Malats, N., Arias Perez, J. I., Benítez, J., Flyger, H., Nordestgaard, B. G., Truong, T., Cordina-Duverger, E., Menegaux, F., dos Santos Silva, I., Fletcher, O., Johnson, N., Häberle, L., Beckmann, M. W., Ekici, A. B., Braaf, L., Atsma, F., van den Broek, A. J., Makalic, E., Schmidt, D. F., Southey, M. C., Cox, A., Simard, J., Giles, G. G., Lambrechts, D., Mannermaa, A., Brauch, H., Guénel, P., Peto, J., Fasching, P. A., Hopper, J., Flesch-Janys, D., Couch, F., Chenevix-Trench, G., Pharoah, P. D. P., Garcia-Closas, M., Schmidt, M. K., Hall, P., Easton, D. F. & Chang-Claude, J., Jan 2014, In: Genetic epidemiology. 38, 1, p. 84-93 10 p.

    Research output: Contribution to journalArticlepeer-review

    22 Scopus citations
  • Identification of nine new susceptibility loci for endometrial cancer

    O’Mara, T. A., Glubb, D. M., Amant, F., Annibali, D., Ashton, K., Attia, J., Auer, P. L., Beckmann, M. W., Black, A., Bolla, M. K., Brauch, H., Brenner, H., Brinton, L., Buchanan, D. D., Burwinkel, B., Chang-Claude, J., Chanock, S. J., Chen, C., Chen, M. M., Cheng, T. H. T., & 105 othersClarke, C. L., Clendenning, M., Cook, L. S., Couch, F. J., Cox, A., Crous-Bous, M., Czene, K., Day, F., Dennis, J., Depreeuw, J., Doherty, J. A., Dörk, T., Dowdy, S. C., Dürst, M., Ekici, A. B., Fasching, P. A., Fridley, B. L., Friedenreich, C. M., Fritschi, L., Fung, J., García-Closas, M., Gaudet, M. M., Giles, G. G., Goode, E. L., Gorman, M., Haiman, C. A., Hall, P., Hankison, S. E., Healey, C. S., Hein, A., Hillemanns, P., Hodgson, S., Hoivik, E. A., Holliday, E. G., Hopper, J. L., Hunter, D. J., Jones, A., Krakstad, C., Kristensen, V. N., Lambrechts, D., Marchand, L. L., Liang, X., Lindblom, A., Lissowska, J., Long, J., Lu, L., Magliocco, A. M., Martin, L., McEvoy, M., Meindl, A., Michailidou, K., Milne, R. L., Mints, M., Montgomery, G. W., Nassir, R., Olsson, H., Orlow, I., Otton, G., Palles, C., Perry, J. R. B., Peto, J., Pooler, L., Prescott, J., Proietto, T., Rebbeck, T. R., Risch, H. A., Rogers, P. A. W., Rübner, M., Runnebaum, I., Sacerdote, C., Sarto, G. E., Schumacher, F., Scott, R. J., Setiawan, V. W., Shah, M., Sheng, X., Shu, X. O., Southey, M. C., Swerdlow, A. J., Tham, E., Trovik, J., Turman, C., Tyrer, J. P., Vachon, C., VanDen Berg, D., Vanderstichele, A., Wang, Z., Webb, P. M., Wentzensen, N., Werner, H. M. J., Winham, S. J., Wolk, A., Xia, L., Xiang, Y. B., Yang, H. P., Yu, H., Zheng, W., Pharoah, P. D. P., Dunning, A. M., Kraft, P., De Vivo, I., Tomlinson, I., Easton, D. F., Spurdle, A. B. & Thompson, D. J., Dec 1 2018, In: Nature communications. 9, 1, 3166.

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    Open Access
    33 Scopus citations
  • Identification of novel genetic markers of breast cancer survival

    Guo, Q., Schmidt, M. K., Kraft, P., Canisius, S., Chen, C., Khan, S., Tyrer, J., Bolla, M. K., Wang, Q., Dennis, J., Michailidou, K., Lush, M., Kar, S., Beesley, J., Dunning, A. M., Shah, M., Czene, K., Darabi, H., Eriksson, M., Lambrechts, D., & 126 othersWeltens, C., Leunen, K., Bojesen, S. E., Nordestgaard, B. G., Nielsen, S. F., Flyger, H., Chang-Claude, J., Rudolph, A., Seibold, P., Flesch-Janys, D., Blomqvist, C., Aittomäki, K., Fagerholm, R., Muranen, T. A., Couch, F. J., Olson, J. E., Vachon, C., Andrulis, I. L., Knight, J. A., Glendon, G., Mulligan, A. M., Broeks, A., Hogervorst, F. B., Haiman, C. A., Henderson, B. E., Schumacher, F., Le Marchand, L., Hopper, J. L., Tsimiklis, H., Apicella, C., Southey, M. C., Cox, A., Cross, S. S., Reed, M. W. R., Giles, G. G., Milne, R. L., McLean, C., Winqvist, R., Pylkäs, K., Jukkola-Vuorinen, A., Grip, M., Hooning, M. J., Hollestelle, A., Martens, J. W. M., Van Den Ouweland, A. M. W., Marme, F., Schneeweiss, A., Yang, R., Burwinkel, B., Figueroa, J., Chanock, S. J., Lissowska, J., Sawyer, E. J., Tomlinson, I., Kerin, M. J., Miller, N., Brenner, H., Dieffenbach, A. K., Arndt, V., Holleczek, B., Mannermaa, A., Kataja, V., Kosma, V. M., Hartikainen, J. M., Li, J., Brand, J. S., Humphreys, K., Devilee, P., Tollenaar, R. A. E. M., Seynaeve, C., Radice, P., Peterlongo, P., Bonanni, B., Mariani, P., Fasching, P. A., Beckmann, M. W., Hein, A., Ekici, A. B., Chenevix-Trench, G., Balleine, R., Phillips, K. A., Benitez, J., Zamora, M. P., Arias Perez, J. I., Menéndez, P., Jakubowska, A., Lubinski, J., Jaworska-Bieniek, K., Durda, K., Hamann, U., Kabisch, M., Ulmer, H. U., Rüdiger, T., Margolin, S., Kristensen, V., Nord, S., Evans, D. G., Abraham, J. E., Earl, H. M., Hiller, L., Dunn, J. A., Bowden, S., Berg, C., Campa, D., Diver, W. R., Gapstur, S. M., Gaudet, M. M., Hankinson, S. E., Hoover, R. N., Hüsing, A., Kaaks, R., Machiela, M. J., Willett, W., Barrdahl, M., Canzian, F., Chin, S. F., Caldas, C., Hunter, D. J., Lindstrom, S., García-Closas, M., Hall, P., Easton, D. F., Eccles, D. M., Rahman, N., Nevanlinna, H. & Pharoah, P. D. P., May 1 2015, In: Journal of the National Cancer Institute. 107, 5

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    35 Scopus citations
  • Identification of six new susceptibility loci for invasive epithelial ovarian cancer

    EMBRACE, GEMO Study Collaborators, Breast cancer Family Registry, HEBON, KConFab investigators, Australian cancer study (ovarian cancer Investigators), Australian Ovarian Cancer Study Group & consortium of Investigators of modifiers of BRCA1 and BRCA2, Jan 1 2015, In: Nature Genetics. 47, 2, p. 164-171 8 p.

    Research output: Contribution to journalArticlepeer-review

    155 Scopus citations
  • Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer

    Milne, R. L., Kuchenbaecker, K. B., Michailidou, K., Beesley, J., Kar, S., Lindström, S., Hui, S., Lemaçon, A., Soucy, P., Dennis, J., Jiang, X., Rostamianfar, A., Finucane, H., Bolla, M. K., McGuffog, L., Wang, Q., Aalfs, C. M., Abctctb, I., Adams, M., Adlard, J., & 461 othersAgata, S., Ahmed, S., Ahsan, H., Aittom, K. Ä., Fares, A. E., Allen, J., Ambrosone, C. B., Amos, C. I., Andrulis, I. L., Anton-Culver, H., Antonenkova, N. N., Arndt, V., Arnold, N., Aronson, K. J., Auber, B., Auer, P. L., Ausems, M. G. M., Azzollini, J., François, B., Balma, J. N., Barile, M., Barjhoux, L., Barkardottir, R. B., Barrdahl, M., Barnes, D., Barrowdale, D., Baynes, C., Beckmann, M. W., Benitez, J., Bermisheva, M., Bernstein, L., Bignon, Y. J., Blazer, K. R., Blok, M. J., Blomqvist, C., Blot, W., Bobolis, K., Boeckx, B., Bogdanova, N. V., Bojesen, A., Bojesen, S. E., Bonanni, B., Anne-Lise, B. D., Bozsik, A., Bradbury, A. R., Brand, J. S., Brauch, H., Brenner, H., Brigitte, B. D. P., Brewer, C., Brinton, L., Broberg, P., Angela, B. W., Brunet, J., Brüning, T., Burwinkel, B., Buys, S. S., Byun, J., Cai, Q., Cald, T. É., Caligo, M. A., Campbell, I., Canzian, F., Caron, O., Carracedo, A., Carter, B. D., Esteban, C., Castera, L., Virginie, C. M., Chan, S. B., Jenny, C. C., Chanock, S. J., Chen, X., Cheng, T. Y. D., Chiquette, J., Christiansen, H., Claes, K. B., Clarke, C. L., Conner, T., Conroy, D. M., Cook, J., Cordina-Duverger, E., Cornelissen, S., Coupier, I., Cox, A., Cox, D. G., Cross, S. S., Cuk, K., Cunningham, J. M., Czene, K., Daly, M. B., Damiola, F., Darabi, H., Davidson, R., Leeneer, K. D. L., Devilee, P., Dicks, E., Diez, O., Ding, Y. C., Ditsch, N., Doheny, K. F., Domchek, S. M., Dorfling, C. M., Dörk, T., Dos-Santos-Silva, I., Dubois, S., Dugué, P. A., Dumont, M., Dunning, A. M., Durcan, L., Dwek, M., Dworniczak, B., Eccles, D., Eeles, R., Ehrencrona, H., Eilber, U., Ejlertsen, B., Ekici, A. B., Eliassen, A. H., Engel, C., Eriksson, M., Fachal, L., Faivre, L., Fasching, P. A., Faust, U., Figueroa, J., Flesch-Janys, D., Fletcher, O., Flyger, H., Foulkes, W. D., Friedman, E., Fritschi, L., Frost, D., Gabrielson, M., Gaddam, P., Gammon, M. D., Ganz, P. A., Gapstur, S. M., Garber, J., Garcia-Barberan, V., Garciá-Saénz, J. A., Gaudet, M. M., Gauthier-Villars, M., Gehrig, A., Georgoulias, V., Gerdes, A. M., Giles, G. G., Glendon, G., Godwin, A. K., Goldberg, M. S., Goldgar, D. E., González-Neira, A., Goodfellow, P., Greene, M. H., Grenaker, G. A. I., Grip, M., Gronwald, J., Grundy, A., Gschwantler, D. K., Guénel, P., Guo, Q., Haeberle, L., Hahnen, E., Haiman, C. A., Håkansson, N., Hallberg, E., Hamann, U., Hamel, N., Hankinson, S., Hansen, T. V., Harrington, P., Hart, S. N., Hartikainen, J. M., Healey, C. S., Hein, A., Helbig, S., Henderson, A., Heyworth, J., Hicks, B., Hillemanns, P., Hodgson, S., Hogervorst, F. B., Hollestelle, A., Hooning, M. J., Hoover, B., Hopper, J. 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H., Lejbkowicz, F., Lesueur, F., Li, J., Lilyquist, J., Lincoln, A., Lindblom, A., Lissowska, J., Lo, W. Y., Loibl, S., Long, J., Loud, J. T., Lubinski, J., Luccarini, C., Lush, M., MacInnis, R. J., Maishman, T., Makalic, E., Kostovska, I. M., Malone, K. E., Siranoush, M., Manson, J. E., Margolin, S., Martens, J. W., Martinez, M. E., Matsuo, K., Mavroudis, D., Mazoyer, S., McLean, C., Meijers-Heijboer, H., Menéndez, P., Meyer, J., Miao, H., Miller, N., Mitchell, G., Montagna, M., Muir, K., Mulligan, A. M., Mulot, C., Nadesan, S., Nathanson, K. L., Neuhausen, S. L., Nevanlinna, H., Nevelsteen, I., Niederacher, D., Nielsen, S. F., Nordestgaard, B. G., Norman, A., Nussbaum, R. L., Olah, E., Olopade, O. I., Olson, J. E., Olswold, C., Ong, K. R., Oosterwijk, J. C., Orr, N., Osorio, A., Pankratz, V. S., Papi, L., Park-Simon, T. W., Paulsson-Karlsson, Y., Lloyd, R., Pedersen, I. S., Peissel, B., Peixoto, A., Perez, J. I., Peterlongo, P., Peto, J., Pfeiler, G., Phelan, C. 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E., Thöne, K., Thull, D. L., Tibiletti, M. G., Tihomirova, L., Tischkowitz, M., Toland, A. E., Tollenaar, R. A. M., Tomlinson, I., Tong, L., Torres, D., Tranchant, M., Truong, T., Tucker, K., Tung, N., Tyrer, J., Ulmer, H. U., Vachon, C., Christi, V. A. J., Den Berg, D. V., Ouweland, A. M. V., Van Rensburg, E. J., Varesco, L., Varon-Mateeva, R., Vega, A., Viel, A., Vijai, J., Vincent, D., Vollenweider, J., Walker, L., Wang, Z., Wang-Gohrke, S., Wappenschmidt, B., Weinberg, C. R., Weitzel, J. N., Wendt, C., Wesseling, J., Whittemore, A. S., Wijnen, J. T., Willett, W., Winqvist, R., Wolk, A., Wu, A. H., Xia, L., Yang, X. R., Yannoukakos, D., Zaffaroni, D., Zheng, W., Zhu, B., Ziogas, A., Ziv, E., Zorn, K. K., Gago-Dominguez, M., Mannermaa, A., Olsson, H., Teixeira, M. R., Stone, J., Offit, K., Ottini, L., Park, S. K., Thomassen, M., Hall, P., Meindl, A., Schmutzler, R. K., Droit, A., Bader, G. D., Pharoah, P. D., Couch, F. J., Easton, D. F., Kraft, P., Chenevix-Trench, G., Garciá-Closas, M., Antoniou, A. C. & Simard, J., Dec 1 2017, In: Nature Genetics. 49, 12, p. 1767-1778 12 p.

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    119 Scopus citations
  • Impact of amino acid substitutions at secondary structures in the BRCT domains of the tumor suppressor BRCA1: Implications for clinical annotation

    Fernandes, V. C., Golubeva, V. A., Pietro, G. D., Shields, C., Amankwah, K., Nepomuceno, T. C., de Gregoriis, G., Abreu, R. B. V., Harro, C., Gomes, T. T., Silva, R. F., Suarez-Kurtz, G., Couch, F. J., Iversen, E. S., Monteiro, A. N. A. & Carvalho, M. A., Apr 12 2019, In: Journal of Biological Chemistry. 294, 15, p. 5980-5992 13 p.

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    12 Scopus citations
  • Impact of histopathology, tumor-infiltrating lymphocytes, and adjuvant chemotherapy on prognosis of triple-negative breast cancer

    Leon-Ferre, R. A., Polley, M. Y., Liu, H., Gilbert, J. A., Cafourek, V., Hillman, D. W., Elkhanany, A., Akinhanmi, M., Lilyquist, J., Thomas, A., Negron, V., Boughey, J. C., Liu, M. C., Ingle, J. N., Kalari, K. R., Couch, F. J., Visscher, D. W. & Goetz, M. P., Jan 1 2018, In: Breast Cancer Research and Treatment. 167, 1, p. 89-99 11 p.

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    34 Scopus citations
  • Impact of personalized genetic breast cancer risk estimation with polygenic risk scores on preventive endocrine therapy intention and uptake

    Kim, J. O., Schaid, D. J., Vachon, C. M., Cooke, A., Couch, F. J., Kim, C. A., Sinnwell, J. P., Hasadsri, L., Stan, D. L., Goldenberg, B., Neal, L., Grenier, D., Degnim, A. C., Thicke, L. A. & Pruthi, S., Feb 1 2021, In: Cancer Prevention Research. 14, 2, p. 175-184 10 p.

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    Open Access
  • Impact that Timing of Genetic Mutation Diagnosis has on Surgical Decision Making and Outcome for BRCA1/BRCA2 Mutation Carriers with Breast Cancer

    Chiba, A., Hoskin, T. L., Hallberg, E. J., Cogswell, J. A., Heins, C. N., Couch, F. J. & Boughey, J. C., Oct 1 2016, In: Annals of surgical oncology. 23, 10, p. 3232-3238 7 p.

    Research output: Contribution to journalArticlepeer-review

    24 Scopus citations
  • Inactivation of Brca2 promotes Trp53-associated but inhibits KrasG12D-dependent pancreatic cancer development in mice

    Rowley, M., Ohashi, A., Mondal, G., Mills, L., Yang, L., Zhang, L., Sundsbak, R., Shapiro, V., Muders, M. H., Smyrk, T. & Couch, F. J., Apr 2011, In: Gastroenterology. 140, 4, p. 1303-1313.e3

    Research output: Contribution to journalArticlepeer-review

    56 Scopus citations
  • Increased prevalence of the BRCA2 polymorphic stop codon K3326X among individuals with familial pancreatic cancer

    Martin, S. T., Matsubayashi, H., Rogers, C. D., Philips, J., Couch, F. J., Brune, K., Yeo, C. J., Kern, S. E., Hruban, R. H. & Goggins, M., May 19 2005, In: Oncogene. 24, 22, p. 3652-3656 5 p.

    Research output: Contribution to journalArticlepeer-review

    65 Scopus citations
  • Induction of the BRCA2 promoter by nuclear factor-κB

    Wu, K., Jiang, S. W., Thangaraju, M., Wu, G. & Couch, F. J., Nov 10 2000, In: Journal of Biological Chemistry. 275, 45, p. 35548-35556 9 p.

    Research output: Contribution to journalArticlepeer-review

    35 Scopus citations
  • Influence of Cancer Susceptibility Gene Mutations and ABO Blood Group of Pancreatic Cancer Probands on Concomitant Risk to First-Degree Relatives

    Antwi, S. O., Rabe, K. G., Bamlet, W. R., Meyer, M., Chandra, S., Fagan, S. E., Hu, C., Couch, F. J., McWilliams, R. R., Oberg, A. L. & Petersen, G. M., Feb 2022, In: Cancer Epidemiology Biomarkers and Prevention. 31, 2, p. 372-381 10 p.

    Research output: Contribution to journalArticlepeer-review

  • Inheritance of deleterious mutations at both BRCA1 and BRCA2 in an international sample of 32,295 women

    HEBON & KConFab investigators, Nov 11 2016, In: Breast Cancer Research. 18, 1, 112.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    20 Scopus citations
  • Inherited mutations in 17 breast cancer susceptibility genes among a large triple-negative breast cancer cohort unselected for family history of breast cancer

    Couch, F. J., Hart, S. N., Sharma, P., Toland, A. E., Wang, X., Miron, P., Olson, J. E., Godwin, A. K., Pankratz, V. S., Olswold, C., Slettedahl, S., Hallberg, E., Guidugli, L., Davila, J., Beckmann, M. W., Janni, W., Rack, B., Ekici, A. B., Slamon, D. J., Konstantopoulou, I., & 21 othersFostira, F., Vratimos, A., Fountzilas, G., Pelttari, L. M., Tapper, W. J., Durcan, L., Cross, S. S., Pilarski, R., Shapiro, C. L., Klemp, J., Yao, S., Garber, J., Cox, A., Brauch, H., Ambrosone, C., Nevanlinna, H., Yannoukakos, D., Slager, S. L., Vachon, C. M., Eccles, D. M. & Fasching, P. A., Feb 1 2015, In: Journal of Clinical Oncology. 33, 4, p. 304-311 8 p.

    Research output: Contribution to journalArticlepeer-review

    370 Scopus citations
  • Inherited variants in the inner centromere protein (INCENP) gene of the chromosomal passenger complex contribute to the susceptibility of ER-negative breast cancer

    The GENICA Network, The GENICA Network, The GENICA Network, The GENICA Network, The GENICA Network, KConFab investigators, Australian Ovarian Cancer Study Group, Australian Ovarian Cancer Study Group, The GENICA Network, The GENICA Network & The GENICA Network, Feb 2014, In: Carcinogenesis. 36, 2, p. 256-271 16 p.

    Research output: Contribution to journalArticlepeer-review

    11 Scopus citations
  • Integrated evaluation of DNA sequence variants of unknown clinical significance: Application to BRCA1 and BRCA2

    Goldgar, D. E., Easton, D. F., Deffenbaugh, A. M., Monteiro, A. N. A., Tavtigian, S. V. & Couch, F. J., Oct 2004, In: American journal of human genetics. 75, 4, p. 535-544 10 p.

    Research output: Contribution to journalArticlepeer-review

    287 Scopus citations
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