Ellen McPhail

2019

False-negative rates for MYC fluorescence in situ hybridization probes in B-cell neoplasms

King, R., McPhail, E., Meyer, R. G., Vasmatzis, G., Pearce, K., Smadbeck, J., Ketterling, R. P., Smoley, S. A., Greipp, P. T., Hoppman, N. L., Peterson, J. F. & Baughn, L., Jun 1 2019, In : Haematologica. 104, 6, p. e248-e251

Research output: Contribution to journal › Letter

6 Scopus citations

First Report of Bilateral External Auditory Canal Cochlin Aggregates (“Cochlinomas”) with Multifocal Amyloid-Like Deposits, Associated with Sensorineural Hearing Loss and a Novel Genetic Variant in COCH Encoding Cochlin

Basu, A., Boczek, N. J., Robertson, N. G., Nasr, S. H., Jethanamest, D., McPhail, E., Kurtin, P. J., Dasari, S., Butz, M., Morton, C. C., Highsmith, W. E. & Zhou, F., Jan 1 2019, (Accepted/In press) In : Head and Neck Pathology.

Research output: Contribution to journal › Article

Heavy Chain Fibrillary Glomerulonephritis: A Case Report

Nasr, S. H., Sirac, C., Bridoux, F., Javaugue, V., Bender, S., Rinsant, A., Kaaki, S., Pinault, E., Dasari, S., Alexander, M. P., Said, S. M., Hogan, J. J., Dispenzieri, A., Touchard, G., McPhail, E. & Leung, N., Jan 1 2019, In : American Journal of Kidney Diseases.

Research output: Contribution to journal › Article

3 Scopus citations

Monoclonal gammopathy plus positive amyloid biopsy does not always equal AL amyloidosis

Sidiqi, M. H., Dasari, S., McPhail, E., Buadi, F. K., Warsame, R., Lacy, M., Dingli, D. M., Gonsalves, W., Kapoor, P., Kourelis, T., Leung, N., Muchtar, E., Grogan, M., Lust, J. A., Kumar, S. K., Kyle, R. A., Rajkumar, S. V., Gertz, M. & Dispenzieri, A., Jan 1 2019, In : American journal of hematology.

Research output: Contribution to journal › Letter

Transthyretin amyloidosis: Putting myopathy on the map

Pinto, M. V., Milone, M., Mauermann, M. L., Dyck, P. J. B., Alhammad, R., McPhail, E. D., Grogan, M. & Liewluck, T., Jan 1 2019, (Accepted/In press) In : Muscle and Nerve.

Research output: Contribution to journal › Article

1 Scopus citations

Two types of amyloidosis presenting in a single patient: a case series

Sidiqi, M. H., McPhail, E., Theis, J. D., Dasari, S., Vrana, J. A., Drosou, M. E., Leung, N., Hayman, S., Rajkumar, S. V., Warsame, R., Ansell, S. M., Gertz, M., Grogan, M. & Dispenzieri, A., Mar 1 2019, In : Blood cancer journal. 9, 3, 30.

Research output: Contribution to journal › Article

3 Scopus citations

2018

Apolipoprotein CII Amyloidosis Associated With p.Lys41Thr Mutation

Sethi, S. M., Dasari, S., Plaisier, E., Ronco, P., Nasr, S. H., Brocheriou, I., Theis, J. D., Vrana, J. A., Zimmermann, M. T., Quint, P. S., McPhail, E. & Kurtin, P. J., Jan 1 2018, (Accepted/In press) In : Kidney International Reports.

Research output: Contribution to journal › Article

3 Scopus citations

Defining lymphoplasmacytic lymphoma: Does MYD88_L265P define a pathologically distinct entity among patients with an IgM paraprotein and bone marrow-based low-grade b-cell lymphomas with plasmacytic differentiation?

Fang, H., Kapoor, P., Gonsalves, W., Frederick, L. A., Viswanatha, D., Howard, M. T., He, R., Morice, W. G., McPhail, E., Greipp, P. T., Ansell, S. M., Kyle, R. A., Gertz, M., Paludo, J., Abeykoon, J. & King, R., Jul 3 2018, In : American Journal of Clinical Pathology. 150, 2, p. 168-176 9 p.

Research output: Contribution to journal › Article

2 Scopus citations

DNAJB9 Is a Specific Immunohistochemical Marker for Fibrillary Glomerulonephritis

Nasr, S. H., Vrana, J. A., Dasari, S., Bridoux, F., Fidler, M. E., Kaaki, S., Quellard, N., Rinsant, A., Goujon, J. M., Sethi, S. M., Fervenza, F. C., Cornell, L. D., Said, S. M., McPhail, E., Herrera Hernandez, L. P., Grande, J. P., Hogan, M. C., Lieske, J. C., Leung, N., Kurtin, P. J. & 1 others, Alexander, M. P., Jan 1 2018, In : Kidney International Reports. 3, 1, p. 56-64 9 p.

Research output: Contribution to journal › Article

19 Scopus citations

Fifty-Year Incidence of Waldenström Macroglobulinemia in Olmsted County, Minnesota, From 1961 Through 2010: A Population-Based Study With Complete Case Capture and Hematopathologic Review

Kyle, R. A., Larson, D. R., McPhail, E., Therneau, T. M., Dispenzieri, A., Kumar, S. K., Kapoor, P., Cerhan, J. R. & Rajkumar, S. V., Jan 1 2018, (Accepted/In press) In : Mayo Clinic Proceedings.

Research output: Contribution to journal › Article

6 Scopus citations

Genetic subtyping of breast implant–associated anaplastic large cell lymphoma

Oishi, N., Brody, G. S., Ketterling, R. P., Viswanatha, D. S., He, R., Dasari, S., Mai, M., Benson, H. K., Sattler, C. A., Luchtel, R., McPhail, E., Bennani, N., Harless, C. A., Singh, K., Clemens, M. W., Medeiros, L. J., Miranda, R. N. & Feldman, A. L., Aug 2 2018, In : Blood. 132, 5, p. 544-547 4 p.

Research output: Contribution to journal › Letter

23 Scopus citations

Inferior survival in high-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements is not associated with MYC/IG gene rearrangements

McPhail, E., Maurer, M. J., Macon, W. R., Feldman, A. L., Kurtin, P. J., Ketterling, R. P., Vaidya, R., Cerhan, J. R., Ansell, S. M., Porrata, L. F., Nowakowski, G. S., Witzig, T. E. & Habermann, T. M., Nov 1 2018, In : Haematologica. 103, 11, p. 1899-1907 9 p.

Research output: Contribution to journal › Article

14 Scopus citations

MYD88 mutation status does not impact overall survival in Waldenström macroglobulinemia

Abeykoon, J. P., Paludo, J., King, R., Ansell, S. M., Gertz, M., LaPlant, B. R., Halvorson, A. E., Gonsalves, W., Dingli, D. M., Fang, H., Rajkumar, S. V., Lacy, M., He, R., Kourelis, T., Reeder, C. B., Novak, A. J., McPhail, E., Viswanatha, D. S., Witzig, T. E., Go, R. S. & 10 others, Habermann, T. M., Buadi, F. K., Dispenzieri, A., Leung, N., Lin, Y., Thompson, C. A., Hayman, S. R., Kyle, R. A., Kumar, S. K. & Kapoor, P., Feb 1 2018, In : American Journal of Hematology. 93, 2, p. 187-194 8 p.

Research output: Contribution to journal › Article

19 Scopus citations

Prognostic and therapeutic significance of phosphorylated STAT3 and protein tyrosine phosphatase-6 in peripheral-T cell lymphoma

Han, J. J., O'byrne, M., Stenson, M. J., Maurer, M. J., Wellik, L. E., Feldman, A. L., McPhail, E., Witzig, T. E. & Gupta, M., Nov 12 2018, In : Blood Cancer Journal. 8, 11, 1 p.

Research output: Contribution to journal › Article

4 Scopus citations

2017

High rate of event-free survival at 24 months with everolimus/RCHOP for untreated diffuse large B-cell lymphoma: updated results from NCCTG N1085 (Alliance)

Witzig, T. E., LaPlant, B., Habermann, T. M., McPhail, E., Inwards, D. J., Micallef, I., Colgan, J. P., Nowakowski, G. S., Ansell, S. M. & Johnston, P. B., Jun 23 2017, In : Blood Cancer Journal. 7, 6, p. e576

Research output: Contribution to journal › Article

7 Scopus citations

Immunophenotypic and laboratory features of t(11;14)(q13;q32)-positive plasma cell neoplasms

Shi, M., Ternus, J. A., Ketterling, R. P., Jevremovic, D. & McPhail, E., Dec 8 2017, (Accepted/In press) In : Leukemia and Lymphoma. p. 1-7 7 p.

Research output: Contribution to journal › Article

1 Scopus citations

2016

Everolimus combined with R-CHOP-21 for new, untreated, diffuse large B-cell lymphoma (NCCTG 1085 [Alliance]): safety and efficacy results of a phase 1 and feasibility trial

Johnston, P. B., LaPlant, B., McPhail, E., Habermann, T. M., Inwards, D. J., Micallef, I., Colgan, J. P., Nowakowski, G. S., Ansell, S. M. & Witzig, T. E., Jul 1 2016, In : The Lancet Haematology. 3, 7, p. e309-e316

Research output: Contribution to journal › Article

27 Scopus citations

LMO2 is a specific marker of T-lymphoblastic leukemia/lymphoma

Jevremovic, D., Roden, A., Ketterling, R. P., Kurtin, P. J. & McPhail, E., Feb 1 2016, In : American Journal of Clinical Pathology. 145, 2, p. 180-190 11 p.

Research output: Contribution to journal › Article

3 Scopus citations

Lymph node

McPhail, E. & Kurtin, P. J., Feb 13 2016, Essentials of Anatomic Pathology: Fourth Edition. Springer International Publishing, p. 751-789 39 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2015

Analysis of Amyloid in Medullary Thyroid Carcinoma by Mass Spectrometry-Based Proteomic Analysis

Erickson, L. A., Vrana, J. A., Theis, J., Rivera, M., Lloyd, R. V., McPhail, E. & Zhang, J., Dec 1 2015, In : Endocrine Pathology. 26, 4, p. 291-295 5 p.

Research output: Contribution to journal › Article

16 Scopus citations

Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue of the salivary glands: A multicenter, international experience of 248 patients (IELSG 41)

Jackson, A. E., Mian, M., Kalpadakis, C., Pangalis, G. A., Stathis, A., Porro, E., Conconi, A., Cortelazzo, S., Gaidano, G., Guillermo, A. L., Johnson, P. W., Martelli, M., Martinelli, G., Thieblemont, C., McPhail, E., Copie-Bergman, C., Pileri, S. A., Jack, A., Campo, E., Mazzucchelli, L. & 5 others, Ristow, K., Habermann, T. M., Cavalli, F., Nowakowski, G. S. & Zucca, E., Aug 12 2015, In : Oncologist. 20, 10, p. 1149-1153 5 p.

Research output: Contribution to journal › Article

17 Scopus citations

Genome-wide analysis uncovers novel recurrent alterations in primary central nervous system lymphomas

Braggio, E. D., Van Wier, S., Ojha, J., McPhail, E., Asmann, Y., Egan, J., Da Silva, J. A., Schiff, D., Lopes, M. B., Decker, P. A., Valdez, R., Tibes, R., Eckloff, B., Witzig, T. E., Stewart, A. K., Fonseca, R. & O'Neill, B. P., Sep 1 2015, In : Clinical Cancer Research. 21, 17, p. 3986-3994 9 p.

Research output: Contribution to journal › Article

75 Scopus citations

Immunophenotypic features by multiparameter flow cytometry can help distinguish low grade B-cell lymphomas with plasmacytic differentiation from plasma cell proliferative disorders with an unrelated clonal B-cell process

Rosado, F. G., Morice, W. G., He, R., Howard, M. T., Timm, M. & McPhail, E., May 1 2015, In : British Journal of Haematology. 169, 3, p. 368-376 9 p.

Research output: Contribution to journal › Article

16 Scopus citations

Morphologic Features of ALK-negative Anaplastic Large Cell Lymphomas With DUSP22 Rearrangements

King, R., Dao, L. N., McPhail, E., Jaffe, E. S., Said, J., Swerdlow, S. H., Sattler, C. A., Ketterling, R. P., Sidhu, J. S., Hsi, E. D., Karikehalli, S., Jiang, L., Gibson, S. E., Ondrejka, S. L., Nicolae, A., Macon, W. R., Dasari, S., Castellar, E. P. & Feldman, A. L., Sep 16 2015, (Accepted/In press) In : American Journal of Surgical Pathology.

Research output: Contribution to journal › Article

33 Scopus citations

Synovial infiltration in human T lymphotropic virus type I-associated adult T cell leukemia/lymphoma

Koster, M., McPhail, E. & Chowdhary, V. R., Apr 1 2015, In : Arthritis and Rheumatology. 67, 4, p. 945 1 p.

Research output: Contribution to journal › Article

Whole-exome analysis reveals novel somatic genomic alterations associated with outcome in immunochemotherapytreated diffuse large B-cell lymphoma

Novak, A. J., Asmann, Y., Maurer, M. J., Wang, C., Slager, S. L., Hodge, L. S., Manske, M., Price-Troska, T., Yang, Z. Z., Zimmermann, M. T., Nowakowski, G. S., Ansell, S. M., Witzig, T. E., McPhail, E., Ketterling, R., Feldman, A. L., Dogan, A., Link, B. K., Habermann, T. M. & Cerhan, J. R., Aug 14 2015, In : Blood Cancer Journal. 5, 8, e346.

Research output: Contribution to journal › Article

34 Scopus citations

2014

A prospective, randomized crossover study comparing direct inspection by light microscopy versus projected images for teaching of hematopathology to medical students

Carlson, A. M., McPhail, E., Rodriguez, V., Schroeder, G. & Wolanskyj, A. P., Mar 2014, In : Anatomical Sciences Education. 7, 2, p. 130-134 5 p.

Research output: Contribution to journal › Article

5 Scopus citations

2013

Clonally related follicular lymphomas and langerhans cell neoplasms: Expanding the spectrum of transdifferentiation

West, D. S., Dogan, A., Quint, P. S., Tricker-Klar, M. L., Porcher, J. C., Ketterling, R. P., Law, M. E., McPhail, E., Viswanatha, D. S., Kurtin, P. J., Dao, L. N., Ritzer, R. D., Nowakowski, G. S. & Feldman, A. L., Jul 2013, In : American Journal of Surgical Pathology. 37, 7, p. 978-986 9 p.

Research output: Contribution to journal › Article

42 Scopus citations

2012

An Integrated Genomic and Expression Analysis of 7q Deletion in Splenic Marginal Zone Lymphoma

Watkins, A. J., Hamoudi, R. A., Zeng, N., Yan, Q., Huang, Y., Liu, H., Zhang, J., Braggio, E. D., Fonseca, R., de Leval, L., Isaacson, P. G., Wotherspoon, A., McPhail, E., Dogan, A. & Du, M. Q., Sep 13 2012, In : PLoS One. 7, 9, e44997.

Research output: Contribution to journal › Article

31 Scopus citations

Detection of human papilloma virus and p16 expression in high-grade adenoid cystic carcinoma of the head and neck

Boland, J. M., McPhail, E., García, J. J., Lewis, J. E. & Schembri-Wismayer, D. J., Apr 2012, In : Modern Pathology. 25, 4, p. 529-536 8 p.

Research output: Contribution to journal › Article

55 Scopus citations

Expression of MALT1 oncogene in hematopoietic stem/progenitor cells recapitulates the pathogenesis of human lymphoma in mice

Vicente-Dueñas, C., Fontán, L., Gonzalez-Herrero, I., Romero-Camarero, I., Segura, V., Aznar, M. A., Alonso-Escudero, E., Campos-Sanchez, E., Ruiz-Roca, L., Barajas-Diego, M., Sagardoy, A., Martinez-Ferrandis, J. I., Abollo-Jimenez, F., Bertolo, C., Peñuelas, I., Garcia-Criado, F. J., García-Cenador, M. B., Tousseyn, T., Agirre, X., Prosper, F. & 15 others, Garcia-Bragado, F., McPhail, E., Lossos, I. S., Du, M. Q., Flores, T., Hernandez-Rivas, J. M., Gonzalez, M., Salar, A., Bellosillo, B., Conde, E., Siebert, R., Sagaert, X., Cobaleda, C., Sanchez-Garcia, I. & Martinez-Climent, J. A., Jun 26 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 26, p. 10534-10539 6 p.

Research output: Contribution to journal › Article

55 Scopus citations

t(X;14)(p11;q32) in MALT lymphoma involving GPR34 reveals a role for GPR34 in tumor cell growth

Ansell, S. M., Akasaka, T., McPhail, E., Manske, M., Braggio, E. D., Price-Troska, T., Ziesmer, S., Secreto, F., Fonseca, R., Gupta, M., Law, M., Witzig, T. E., Dyer, M. J. S., Dogan, A., Cerhan, J. R. & Novak, A. J., Nov 8 2012, In : Blood. 120, 19, p. 3949-3957 9 p.

Research output: Contribution to journal › Article

25 Scopus citations

2011

BCL-6 expression in mesenchymal tumours: An immunohistochemical and fluorescence in situ hybridisation study

Walters, M. P., McPhail, E., Law, M. E. & Folpe, A. L., Oct 2011, In : Journal of Clinical Pathology. 64, 10, p. 866-869 4 p.

Research output: Contribution to journal › Article

4 Scopus citations

Influence of 6q22-23 on overall survival in primary central nervous system lymphoma. Analysis of North Central Cancer Treatment Group trials 86 72 52, 93 73 51 and 96 73 51

McPhail, E., Law, M. E., Decker, P. A. & O'Neill, B. P., Jul 2011, In : British Journal of Haematology. 154, 1, p. 146-150 5 p.

Research output: Contribution to journal › Article

3 Scopus citations

Primary central nervous system lymphomas: A validation study of array-based comparative genomic hybridization in formalin-fixed paraffin-embedded tumor specimens

Braggio, E. D., McPhail, E., Macon, W., Lopes, M. B., Schiff, D., Law, M., Fink, S., Sprau, D., Giannini, C., Dogan, A., Fonseca, R. & O'Neill, B. P., Jul 1 2011, In : Clinical Cancer Research. 17, 13, p. 4245-4253 9 p.

Research output: Contribution to journal › Article

35 Scopus citations

Relapsed hepatosplenic T-cell lymphoma heralded by a solitary skin nodule

Hocker, T. L., Wada, D. A., McPhail, E., Porrata, L. F., El-Azhary, R. A. & Gibson, L. E., Nov 2011, In : Journal of Cutaneous Pathology. 38, 11, p. 899-904 6 p.

Research output: Contribution to journal › Article

3 Scopus citations

2010

CD5+ B-cell lymphoproliferative disorders: Beyond chronic lymphocytic leukemia and mantle cell lymphoma

Jevremovic, D., Dronca, R. S., Morice, W. G., McPhail, E., Kurtin, P. J., Zent, C. S. & Hanson, C. A., Sep 2010, In : Leukemia Research. 34, 9, p. 1235-1238 4 p.

Research output: Contribution to journal › Article

23 Scopus citations

Coexisting follicular and mantle cell lymphoma with each having an in situ component: A novel, curious, and complex consultation case of coincidental, composite, colonizing lymphoma

Roullet, M. R., Martinez, D., Ma, L., Fowler, M. H., McPhail, E., Judkins, A., Arber, D. A. & Bagg, A., Apr 2010, In : American Journal of Clinical Pathology. 133, 4, p. 584-591 8 p.

Research output: Contribution to journal › Article

45 Scopus citations

Defining the borders of splenic marginal zone lymphoma: a multiparameter study

Dufresne, S. D., Felgar, R. E., Sargent, R. L., Surti, U., Gollin, S. M., McPhail, E., Cook, J. R. & Swerdlow, S. H., Apr 2010, In : Human Pathology. 41, 4, p. 540-551 12 p.

Research output: Contribution to journal › Article

17 Scopus citations

Expression of LMO2 is associated with t(14;18)/IGH-BCL2 fusion but not BCL6 translocations in diffuse large B-cell lymphoma

Durnick, D. K., Law, M. E., Maurer, M. J., Natkunam, Y., Levy, R., Lossos, I. S., Kurtin, P. J. & McPhail, E., Aug 2010, In : American Journal of Clinical Pathology. 134, 2, p. 278-281 4 p.

Research output: Contribution to journal › Article

7 Scopus citations

Splenic marginal zone lymphoma: Characterization of 7q deletion and its value in diagnosis

James Watkins, A., Huang, Y., Ye, H., Chanudet, E., Johnson, N., Hamoudi, R., Liu, H., Dong, G., Attygalle, A., McPhail, E., Law, M. E., Isaacson, P. G., De Leval, L., Wotherspoon, A. & Du, M. Q., Mar 2010, In : Journal of Pathology. 220, 4, p. 461-474 14 p.

Research output: Contribution to journal › Article

42 Scopus citations

2009

Cyclin D1 positive follicular lymphoma

Olsen, B., Srkalovic, G., Hall, M. & McPhail, E., Sep 2009, In : Journal of Clinical Pathology. 62, 9, p. 855-857 3 p.

Research output: Contribution to journal › Article

5 Scopus citations

Gene expression profiling of pulmonary mucosa-associated lymphoid tissue lymphoma identifies new biologic insights with potential diagnostic and therapeutic applications

Chng, W. J., McPhail, E., Fonseca, R., Bergsagel, P. L., Vrana, J. A., Kurtin, P. J. & Dogan, A., Jan 15 2009, In : Blood. 113, 3, p. 635-645 11 p.

Research output: Contribution to journal › Article

30 Scopus citations

Novel immunophenotypic features of marrow lymphoplasmacytic lymphoma and correlation with Waldenström's macroglobulinemia

Morice, W. G., Chen, D., Kurtin, P. J., Hanson, C. A. & McPhail, E., Jun 2009, In : Modern Pathology. 22, 6, p. 807-816 10 p.

Research output: Contribution to journal › Article

112 Scopus citations

Recurrent translocations involving the IRF4 oncogene locus in peripheral T-cell lymphomas

Feldman, A. L., Law, M., McPhail, E., Macon, W. R., Erickson, L. A., Grogg, K. L., Kurtin, P. J. & Dogan, A., 2009, In : Leukemia. 23, 3, p. 574-580 7 p.

Research output: Contribution to journal › Article

141 Scopus citations

Sclerosing extramedullary hematopoietic tumor: emphasis on diagnosis by renal biopsy

Sukov, W. R., McPhail, E., Nascimento, A. G., Sethi, S. M. & Lewin, M., Apr 2009, In : Annals of Diagnostic Pathology. 13, 2, p. 127-131 5 p.

Research output: Contribution to journal › Article

8 Scopus citations

2008

Chromosomal translocations involving BCL6 in MALT lymphoma

Ye, H., McPhail, E., Bacon, C. M., Nicholson, A. G., Dogan, A. & Du, M. Q., Jan 2008, In : Haematologica. 93, 1, p. 145-146 2 p.

Research output: Contribution to journal › Article

19 Scopus citations

Del(6)(q22) and BCL6 rearrangements in primary CNS lymphoma are indicators of an aggressive clinical course

Cady, F. M., O'Neill, B. P., Law, M. E., Decker, P. A., Kurtz, D. M., Giannini, C., Porter Umphrey, A. B., Kurtin, P. J., Johnston, P. B., Dogan, A. & McPhail, E., Oct 10 2008, In : Journal of Clinical Oncology. 26, 29, p. 4814-4819 6 p.

Research output: Contribution to journal › Article

74 Scopus citations

Incidence of TCR and TCL1 gene translocations and isochromosome 7q in peripheral T-cell lymphomas using fluorescence in situ hybridization

Feldman, A. L., Law, M., Grogg, K. L., Thorland, E. C., Fink, S., Kurtin, P. J., Macon, W. R., McPhail, E. & Dogan, A., Aug 2008, In : American Journal of Clinical Pathology. 130, 2, p. 178-185 8 p.

Research output: Contribution to journal › Article

32 Scopus citations

Overexpression of Syk tyrosine kinase in peripheral T-cell lymphomas

Feldman, A. L., Sun, D. X., Law, M. E., Novak, A. J., Attygalle, A. D., Thorland, E. C., Fink, S. R., Vrana, J. A., Caron, B. L., Morice, W. G., McPhail, E., Grogg, K. L., Kurtin, P. J., Macon, W. R. & Dogan, A., Jun 2008, In : Leukemia. 22, 6, p. 1139-1143 5 p.

Research output: Contribution to journal › Article

103 Scopus citations

Ellen McPhail, MD