Diane F Jelinek, PhD

  • 11070 Citations
  • 63 Scopus h-Index
1981 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

Filter
Article
2010

Phase II trials of single-agent anti-VEGF therapy for patients with chronic lymphocytic leukemia

Shanafelt, T., Zent, C., Byrd, J., Erlichman, C., Laplant, B., Ghosh, A., Call, T., Villalona-Calero, M., Jelinek, D., Bowen, D., Laumann, K., Wu, W., Hanson, C. & Kay, N., Dec 2010, In : Leukemia and Lymphoma. 51, 12, p. 2222-2229 8 p.

Research output: Contribution to journalArticle

26 Scopus citations

Platelet-derived growth factor (PDGF)-PDGF receptor interaction activates bone marrow-derived mesenchymal stromal cells derived from chronic lymphocytic leukemia: Implications for an angiogenic switch

Ding, W., Knox, T. R., Tschumper, R. C., Wu, W., Schwager, S. M., Boysen, J. C., Jelinek, D. F. & Kay, N. E., Oct 21 2010, In : Blood. 116, 16, p. 2984-2993 10 p.

Research output: Contribution to journalArticle

88 Scopus citations

Prevalence and risk of progression of light-chain monoclonal gammopathy of undetermined significance: a retrospective population-based cohort study

Dispenzieri, A., Katzmann, J. A., Kyle, R. A., Larson, D. R., Melton, L. J., Colby, C. L., Therneau, T. M., Clark, R., Kumar, S. K., Bradwell, A., Fonseca, R., Jelinek, DF. F. & Rajkumar, S. V., 2010, In : The Lancet. 375, 9727, p. 1721-1728 8 p.

Research output: Contribution to journalArticle

215 Scopus citations

Progressive but previously untreated CLL patients with greater array CGH complexity exhibit a less durable response to chemoimmunotherapy

Kay, N. E., Eckel-Passow, J. E., Braggio, E., VanWier, S., Shanafelt, T. D., Van Dyke, D. L., Jelinek, D. F., Tschumper, R. C., Kipps, T., Byrd, J. C. & Fonseca, R., Dec 2010, In : Cancer Genetics and Cytogenetics. 203, 2, p. 161-168 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

Selective Induction of DNA Repair Pathways in Human B Cells Activated by CD4+ T Cells

Wu, X., Tschumper, R. C., Gutierrez, A., Mihalcik, S. A., Nowakowski, G. S. & Jelinek, D. F., 2010, In : PloS one. 5, 12, e15549.

Research output: Contribution to journalArticle

7 Scopus citations

The structure of the TNFRSF13C promoter enables differential expression of BAFF-R during B cell ontogeny and terminal differentiation

Mihalcik, S. A., Huddleston, P. M., Wu, X. & Jelinek, D. F., Jul 15 2010, In : Journal of Immunology. 185, 2, p. 1045-1054 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

Transcriptional and post-transcriptional mechanisms of BAFF-receptor dysregulation in human B lineage malignancies

Mihalcik, S. A., Tschumper, R. C. & Jelinek, D. F., Dec 15 2010, In : Cell Cycle. 9, 24, p. 4884-4892 9 p.

Research output: Contribution to journalArticle

10 Scopus citations
2009

Autoimmune cytopenia in chronic lymphocytic leukemia/small lymphocytic lymphoma: Changes in clinical presentation and prognosis

Zent, C. S., Ding, W., Reinalda, M. S., Schwager, S. M., Hoyer, J. D., Bowen, D. A., Jelinek, D. F., Tschumper, R. C., Call, T. G., Shanafelt, T. D., Kay, N. E. & Slager, S. L., 2009, In : Leukemia and Lymphoma. 50, 8, p. 1261-1268 8 p.

Research output: Contribution to journalArticle

54 Scopus citations

B-cell count and survival: Differentiating chronic lymphocytic leukemia from monoclonal B-cell lymphocytosis based on clinical outcome

Shanafelt, T. D., Kay, N. E., Jenkins, G., Call, T. G., Zent, C. S., Jelinek, D. F., Morice, W. G., Boysen, J., Zakko, L., Schwager, S., Slager, S. L. & Hanson, C. A., 2009, In : Blood. 113, 18, p. 4188-4196 9 p.

Research output: Contribution to journalArticle

90 Scopus citations

Brief report: Natural history of individuals with clinically recognized monoclonal B-cell lymphocytosis compared with patients with Rai 0 chronic lymphocytic leukemia

Shanafelt, T. D., Kay, N. E., Rabe, K. G., Call, T. G., Zent, C. S., Maddocks, K., Jenkins, G., Jelinek, D. F., Morice, W. G., Boysen, J., Schwager, S., Bowen, D., Slager, S. L. & Hanson, C. A., Aug 20 2009, In : Journal of Clinical Oncology. 27, 24, p. 3959-3963 5 p.

Research output: Contribution to journalArticle

102 Scopus citations

Increased signaling through p62 in the marrow microenvironment increases myeloma cell growth and osteoclast formation

Hiruma, Y., Honjo, T., Jelinek, D. F., Windle, J. J., Shin, J., Roodman, G. D. & Kurihara, N., 2009, In : Blood. 113, 20, p. 4894-4902 9 p.

Research output: Contribution to journalArticle

40 Scopus citations

Mcl-1 expression predicts progression-free survival in chronic lymphocytic leukemia patients treated with pentostatin, cyclophosphamide, and rituximab

Awan, F. T., Kay, N. E., Davis, M. E., Wu, W., Geyer, S. M., Leung, N., Jelinek, D. F., Tschumper, R. C., Secreto, C. R., Lin, T. S., Grever, M. R., Shanafelt, T. D., Zent, C. S., Call, T. G., Heerema, N. A., Lozanski, G., Byrd, J. C. & Lucas, D. M., Jan 15 2009, In : Blood. 113, 3, p. 535-537 3 p.

Research output: Contribution to journalArticle

51 Scopus citations

Percentage of smudge cells on routine blood smear predicts survival in chronic lymphocytic leukemia

Nowakowski, G. S., Hoyer, J. D., Shanafelt, T. D., Zent, C. S., Call, T. G., Bone, N. D., Laplant, B., Dewald, G. W., Tschumper, R. C., Jelinek, D. F., Witzig, T. E. & Kay, N. E., Apr 10 2009, In : Journal of Clinical Oncology. 27, 11, p. 1844-1849 6 p.

Research output: Contribution to journalArticle

52 Scopus citations

Phase I trial of daily oral polyphenon E in patients with asymptomatic rai stage 0 to II chronic lymphocytic leukemia

Shanafelt, T. D., Call, T. G., Zent, C. S., LaPlant, B., Bowen, D. A., Roos, M., Secreto, C. R., Ghosh, A. K., Kabat, B. F., Lee, M. J., Yang, C. S., Jelinek, D. F., Erlichman, C. & Kay, N. E., Aug 10 2009, In : Journal of Clinical Oncology. 27, 23, p. 3808-3814 7 p.

Research output: Contribution to journalArticle

121 Scopus citations

Validation of a new prognostic index for patients with chronic lymphocytic leukemia

Shanafelt, T. D., Jenkins, G., Call, T. G., Zent, C. S., Slager, S., Bowen, D. A., Schwager, S., Hanson, C. A., Jelinek, D. F. & Kay, N. E., Jan 15 2009, In : Cancer. 115, 2, p. 363-372 10 p.

Research output: Contribution to journalArticle

62 Scopus citations
2008

Alternative splicing regulates activation-induced cytidine deaminase (AID): Implications for suppression of AID mutagenic activity in normal and malignant B cells

Wu, X., Darce, J. R., Chang, S. K., Nowakowski, G. S. & Jelinek, D. F., Dec 1 2008, In : Blood. 112, 12, p. 4675-4682 8 p.

Research output: Contribution to journalArticle

34 Scopus citations

Biologic and genetic characterization of the novel amyloidogenic lambda light chain-secreting human cell lines, ALMC-1 and ALMC-2

Arendt, B. K., Ramirez-Alvarado, M., Sikkink, L. A., Keats, J. J., Ahmann, G. J., Dispenzieri, A., Fonseca, R., Ketterling, R. P., Knudson, R. A., Mulvihill, E. M., Tschumper, R. C., Wu, X., Zeldenrust, S. R. & Jelinek, D. F., Sep 1 2008, In : Blood. 112, 5, p. 1931-1941 11 p.

Research output: Contribution to journalArticle

44 Scopus citations

B lymphocyte stimulator regulates adaptive immune responses by directly promoting dendritic cell maturation

Chang, S. K., Mihalcik, S. A. & Jelinek, D. F., 2008, In : Journal of Immunology. 180, 11, p. 7394-7403 10 p.

Research output: Contribution to journalArticle

Open Access
40 Scopus citations

CD49d expression is an independent predictor of overall survival in patients with chronic lymphocytic leukaemia: A prognostic parameter with therapeutic potential

Shanafelt, T. D., Geyer, S. M., Bone, N. D., Tschumper, R. C., Witzig, T. E., Nowakowski, G. S., Zent, C. S., Call, T. G., LaPlant, B., Dewald, G. W., Jelinek, D. F. & Kay, N. E., Mar 2008, In : British journal of haematology. 140, 5, p. 537-546 10 p.

Research output: Contribution to journalArticle

111 Scopus citations

Direct and complement dependent cytotoxicity in CLL cells from patients with high-risk early-intermediate stage chronic lymphocytic leukemia (CLL) treated with alemtuzumab and rituximab

Zent, C. S., Secreto, C. R., LaPlant, B. R., Bone, N. D., Call, T. G., Shanafelt, T. D., Jelinek, D. F., Tschumper, R. C. & Kay, N. E., Dec 2008, In : Leukemia Research. 32, 12, p. 1849-1856 8 p.

Research output: Contribution to journalArticle

61 Scopus citations

Early treatment of high-risk chronic lymphocytic leukemia with alemtuzumab and rituximab

Zent, C. S., Call, T. G., Shanafelt, T. D., Tschumper, R. C., Jelinek, D. F., Bowen, D. A., Secreto, C. R., LaPlant, B. R., Kabat, B. F. & Kay, N. E., Oct 15 2008, In : Cancer. 113, 8, p. 2110-2118 9 p.

Research output: Contribution to journalArticle

70 Scopus citations

Immunoglobulin diversity gene usage predicts unfavorable outcome in a subset of chronic lymphocytic leukemia patients

Tschumper, R. C., Geyer, S. M., Campbell, M. E., Kay, N. E., Shanafelt, T. D., Zent, C. S., Nowakowski, G. S., Call, T. G., Dewald, G. W. & Jelinek, D. F., Jan 2 2008, In : Journal of Clinical Investigation. 118, 1, p. 306-315 10 p.

Research output: Contribution to journalArticle

20 Scopus citations

Immunoglobulin free light chain ratio is an independent risk factor for progression of smoldering (asymptomatic) multiple myeloma

Dispenzieri, A., Kyle, R. A., Katzmann, J. A., Therneau, T. M., Larson, D., Benson, J., Clark, R. J., Melton, L. J., Gertz, M. A., Kumar, S. K., Fonseca, R., Jelinek, D. F. & Rajkumar, S. V., Jan 15 2008, In : Blood. 111, 2, p. 785-789 5 p.

Research output: Contribution to journalArticle

289 Scopus citations

MBL or CLL: Which classification best categorizes the clinical course of patients with an absolute lymphocyte count ≥ 5 × 109 L-1 but a B-cell lymphocyte count < 5 × 109 L-1?

Shanafelt, T. D., Kay, N. E., Call, T. G., Zent, C. S., Jelinek, D. F., LaPlant, B., Morice, W. G. & Hanson, C. A., Sep 2008, In : Leukemia Research. 32, 9, p. 1458-1461 4 p.

Research output: Contribution to journalArticle

38 Scopus citations

Prognostic importance of T and NK-cells in a consecutive series of newly diagnosed patients with chronic lymphocytic leukaemia

Palmer, S., Hanson, C. A., Zent, C. S., Porrata, L. F., LaPlant, B., Geyer, S. M., Markovic, S. N., Call, T. G., Bowen, D. A., Jelinek, D. F., Kay, N. E. & Shanafelt, T. D., Jun 2008, In : British journal of haematology. 141, 5, p. 607-614 8 p.

Research output: Contribution to journalArticle

57 Scopus citations

The prognostic significance of cytopenia in chronic lymphocytic leukaemia/small lymphocytic lymphoma

Zent, C. S., Ding, W., Schwager, S. M., Reinalda, M. S., Hoyer, J. D., Jelinek, D. F., Tschumper, R. C., Bowen, D. A., Call, T. G., Shanafelt, T. D., Kay, N. E. & Slager, S. L., Jun 2008, In : British journal of haematology. 141, 5, p. 615-621 7 p.

Research output: Contribution to journalArticle

84 Scopus citations
2007

Clinical course and prognosis of smoldering (asymptomatic) multiple myeloma

Kyle, R. A., Remstein, E. D., Therneau, T. M., Dispenzieri, A., Kurtin, P. J., Hodnefield, J. M., Larson, D. R., Plevak, M. F., Jelinek, D. F., Fonseca, R., Melton, L. J. & Rajkumar, S. V., Jun 21 2007, In : New England Journal of Medicine. 356, 25, p. 2582-2590 9 p.

Research output: Contribution to journalArticle

484 Scopus citations

Combination chemoimmunotherapy with pentostatin, cyclophosphamide, and rituximab shows significant clinical activity with low accompanying toxicity in previously untreated B chronic lymphocytic leukemia

Kay, N. E., Geyer, S. M., Call, T. G., Shanafelt, T. D., Zent, C. S., Jelinek, D. F., Tschumper, R., Bone, N. D., Dewald, G. W., Lin, T. S., Heerema, N. A., Smith, L., Grever, M. R. & Byrd, J. C., Jan 15 2007, In : Blood. 109, 2, p. 405-411 7 p.

Research output: Contribution to journalArticle

252 Scopus citations

Comprehensive assessment of genetic and molecular features predicting outcome in patients with chronic lymphocytic leukemia: Results from the US intergroup phase III trial E2997

Grever, M. R., Lucas, D. M., Dewald, G. W., Neuberg, D. S., Reed, J. C., Kitada, S., Flinn, I. W., Tallman, M. S., Appelbaum, F. R., Larson, R. A., Paietta, E., Jelinek, D. F., Gribben, J. G. & Byrd, J. C., Mar 1 2007, In : Journal of Clinical Oncology. 25, 7, p. 799-804 6 p.

Research output: Contribution to journalArticle

276 Scopus citations

Divergent effects of BAFF on human memory B cell differentiation into Ig-secreting cells

Darce, J. R., Arendt, B. K., Sook, K. C. & Jelinek, D. F., May 1 2007, In : Journal of Immunology. 178, 9, p. 5612-5622 11 p.

Research output: Contribution to journalArticle

Open Access
47 Scopus citations

Elevation of soluble CD307 (IRTA2/FcRH5) protein in the blood and expression on malignant cells of patients with multiple myeloma, chronic lymphocytic leukemia, and mantle cell lymphoma

Ise, T., Nagata, S., Kreitman, R. J., Wilson, W. H., Wayne, A. S., Stetler-Stevenson, M., Bishop, M. R., Scheinberg, D. A., Rassenti, L., Kipps, T. J., Kyle, R. A., Jelinek, D. F. & Pastan, I., Jan 2007, In : Leukemia. 21, 1, p. 169-174 6 p.

Research output: Contribution to journalArticle

31 Scopus citations

Expression of TCL-1 as a potential prognostic factor for treatment outcome in B-cell chronic lymphocytic leukemia

Browning, R. L., Geyer, S. M., Johnson, A. J., Jelinek, D. F., Tschumper, R. C., Call, T. G., Shanafelt, T. D., Zent, C. S., Bone, N. D., Dewald, G. W., Lin, T. S., Heerema, N. A., Grever, M. R., Kay, N. E., Byrd, J. C. & Lucas, D. M., Dec 2007, In : Leukemia Research. 31, 12, p. 1737-1740 4 p.

Research output: Contribution to journalArticle

13 Scopus citations

Genetic variation in 1253 immune and inflammation genes and risk of non-Hodgkin lymphoma

Cerhan, J. R., Ansell, S. M., Fredericksen, Z. S., Kay, N. E., Liebow, M., Call, T. G., Dogan, A., Cunningham, J. M., Wang, A. H., Liu-Mares, W., Macon, W. R., Jelinek, D., Witzig, T. E., Habermann, T. M. & Slager, S. L., Dec 15 2007, In : Blood. 110, 13, p. 4455-4463 9 p.

Research output: Contribution to journalArticle

111 Scopus citations

Methylprednisolone-rituximab is an effective salvage therapy for patients with relapsed chronic lymphocytic leukemia including those with unfavorable cytogenetic features

Bowen, D. A., Call, T. G., Jenkins, G. D., Zent, C. S., Schwager, S. M., Van Dyke, D. L., Jelinek, D. F., Kay, N. E. & Shanafelt, T. D., Dec 1 2007, In : Leukemia and Lymphoma. 48, 12, p. 2412-2417 6 p.

Research output: Contribution to journalArticle

86 Scopus citations

Regulated expression of BAFF-binding receptors during human B cell differentiation

Darce, J. R., Arendt, B. K., Wu, X. & Jelinek, D. F., Dec 1 2007, In : Journal of Immunology. 179, 11, p. 7276-7286 11 p.

Research output: Contribution to journalArticle

Open Access
171 Scopus citations

Risk factors for development of a second lymphoid malignancy in patients with chronic lymphocytic leukaemia

Maddocks-Christianson, K., Slager, S. L., Zent, C. S., Reinalda, M., Call, T. G., Habermann, T. M., Bowen, D. A., Hoyer, J. D., Schwager, S., Jelinek, D. F., Kay, N. E. & Shanafelt, T. D., Nov 2007, In : British journal of haematology. 139, 3, p. 398-404 7 p.

Research output: Contribution to journalArticle

64 Scopus citations

Using smudge cells on routine blood smears to predict clinical outcome in chronic lymphocytic leukemia: A universally available prognostic test

Nowakowski, G. S., Hoyer, J. D., Shanafelt, T. D., Geyer, S. M., LaPlant, B. R., Call, T. G., Jelinek, D. F., Zent, C. S. & Kay, N. E., Apr 2007, In : Mayo Clinic proceedings. 82, 4, p. 449-453 5 p.

Research output: Contribution to journalArticle

33 Scopus citations
2006

A role for BLyS in the activation of innate immune cells

Sook, K. C., Arendt, B. K., Darce, J. R., Wu, X. & Jelinek, D. F., Oct 15 2006, In : Blood. 108, 8, p. 2687-2694 8 p.

Research output: Contribution to journalArticle

76 Scopus citations

Elevated serum B-lymphocyte stimulator levels in patients with familial lymphoproliferative disorders

Novak, A. J., Grote, D. M., Ziesmer, S. C., Kline, M. P., Manske, M. K., Slager, S., Witzig, T. E., Shanafelt, T., Call, T. G., Kay, N. E., Jelinek, D. F., Cerhan, J. R., Gross, J. A., Harder, B., Dillon, S. R. & Ansell, S. M., Feb 20 2006, In : Journal of Clinical Oncology. 24, 6, p. 983-987 5 p.

Research output: Contribution to journalArticle

69 Scopus citations

Gene-expression profiling of Waldenström macroglobulinemia reveals a phenotype more similar to chronic lymphocytic leukemia than multiple myeloma

Chng, W. J., Schop, R. F., Price-Troska, T., Ghobrial, I., Kay, N., Jelinek, D. F., Gertz, M. A., Dispenzieri, A., Lacy, M., Kyle, R. A., Greipp, P. R., Tschumper, R. C., Fonseca, R. & Bergsagel, P. L., Oct 15 2006, In : Blood. 108, 8, p. 2755-2763 9 p.

Research output: Contribution to journalArticle

126 Scopus citations

Prospective evaluation of clonal evolution during long-term follow-up of patients with untreated early-stage chronic lymphocytic leukemia

Shanafelt, T. D., Witzig, T. E., Fink, S. R., Jenkins, R. B., Paternoster, S. F., Smoley, S. A., Stockero, K. J., Nast, D. M., Flynn, H. C., Tschumper, R. C., Geyer, S., Zent, C. S., Call, T. G., Jelinek, D. F., Kay, N. E. & Dewald, G. W., Oct 1 2006, In : Journal of Clinical Oncology. 24, 28, p. 4634-4641 8 p.

Research output: Contribution to journalArticle

198 Scopus citations
2005

A-Miz-ing BCL6

Wu, X. & Jelinek, D. F., Oct 1 2005, In : Nature immunology. 6, 10, p. 964-966 3 p.

Research output: Contribution to journalArticle

5 Scopus citations

A recombinant IL-4-Pseudomonas exotoxin inhibits protein synthesis and overcomes apoptosis resistance in human CLL B cells

Kay, N. E., Bone, N. D., Lee, Y. K., Jelinek, D. F., Leland, P., Battle, T. E., Frank, D. A. & Puri, R. K., Sep 1 2005, In : Leukemia Research. 29, 9, p. 1009-1018 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

CD38 expression levels in chronic lymphocytic leukemia B cells are associated with activation marker expression and differential responses to interferon stimulation

Pittner, B. T., Shanafelt, T. D., Kay, N. E. & Jelinek, D. F., Dec 2005, In : Leukemia. 19, 12, p. 2264-2272 9 p.

Research output: Contribution to journalArticle

41 Scopus citations

Fluorescent-labeled DNA probes applied to novel biological aspects of B-cell chronic lymphocytic leukemia

Fink, S. R., Paternoster, S. F., Smoley, S. A., Flynn, H. C., Geyer, S. M., Shanafelt, T. D., Lee, Y. K., Jelinek, D. F., Kay, N. E. & Dewald, G. W., Mar 1 2005, In : Leukemia Research. 29, 3, p. 253-262 10 p.

Research output: Contribution to journalArticle

27 Scopus citations

MIP-1α utilizes both CCR1 and CCR5 to induce osteoclast formation and increase adhesion of myeloma cells to marrow stromal cells

Oba, Y., Lee, J. W., Ehrlich, L. A., Chung, H. Y., Jelinek, D. F., Callander, N. S., Horuk, R., Choi, S. J. & Roodman, G. D., Mar 2005, In : Experimental Hematology. 33, 3, p. 272-278 7 p.

Research output: Contribution to journalArticle

118 Scopus citations
12 Scopus citations
15 Scopus citations

Selective inhibition of inflammatory gene expression in activated T lymphocytes: A mechanism of immune suppression by thiopurines

Thomas, C. W., Myhre, G. M., Tschumper, R., Sreekumar, R., Jelinek, D., McKean, D. J., Lipsky, J. J., Sandborn, W. J. & Egan, L. J., Feb 2005, In : Journal of Pharmacology and Experimental Therapeutics. 312, 2, p. 537-545 9 p.

Research output: Contribution to journalArticle

94 Scopus citations

VEGF receptors on chronic lymphocytic leukemia (CCL) B cells interact with STAT 1 and 3: Implication for apoptosis resistance

Lee, Y. K., Shanafelt, T. D., Bone, N. D., Strege, A. K., Jelinek, D. F. & Kay, N. E., Apr 2005, In : Leukemia. 19, 4, p. 513-523 11 p.

Research output: Contribution to journalArticle

110 Scopus citations