Diane F Jelinek, PhD

  • 10477 Citations
  • 60 Scopus h-Index
1981 …2020
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Research Output 1981 2019

  • 10477 Citations
  • 60 Scopus h-Index
  • 196 Article
  • 3 Chapter
  • 1 Letter
2019
9 Citations (Scopus)

Ibrutinib-Rituximab or Chemoimmunotherapy for Chronic Lymphocytic Leukemia

Shanafelt, T. D., Wang, X. V., Kay, N. E., Hanson, C. A., O'Brien, S., Barrientos, J., Jelinek, D. F., Braggio, E., Leis, J. F., Zhang, C. C., Coutre, S. E., Barr, P. M., Cashen, A. F., Mato, A. R., Singh, A. K., Mullane, M. P., Little, R. F., Erba, H., Stone, R. M., Litzow, M. & 1 others, Tallman, M., Aug 1 2019, In : The New England journal of medicine. 381, 5, p. 432-443 12 p.

Research output: Contribution to journalArticle

B-Cell Chronic Lymphocytic Leukemia
Disease-Free Survival
Confidence Intervals
Immunoglobulin Heavy Chains
Cyclophosphamide
1 Citation (Scopus)

Role of long non-coding RNAs in disease progression of early stage unmutated chronic lymphocytic leukemia

Tschumper, R. C., Shanafelt, T. D., Kay, N. E. & Jelinek, D. F., Jan 1 2019, In : Oncotarget. 10, 1, p. 60-75 16 p.

Research output: Contribution to journalArticle

Long Noncoding RNA
B-Cell Chronic Lymphocytic Leukemia
Disease Progression
Immunoglobulin Heavy Chains
Biological Phenomena
2018

Characterization and use of the novel human multiple myeloma cell line MC-B11/14 to study biological consequences of CRISPR-mediated loss of immunoglobulin A heavy chain

Walters, D. K., Arendt, B. K., Tschumper, R. C., Wu, X. & Jelinek, D. F., Jan 1 2018, In : Experimental Hematology. 57, p. 42-49.e1

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Immunoglobulin Heavy Chains
Multiple Myeloma
Immunoglobulin A
Cell Line
5 Citations (Scopus)

No improvement in long-term survival over time for chronic lymphocytic leukemia patients in stereotyped subsets #1 and #2 treated with chemo(Immuno)therapy

Baliakas, P., Mattsson, M., Hadzidimitriou, A., Minga, E., Agathangelidis, A., Sutton, L. A., Scarfo, L., Davis, Z., Yan, X. J., Plevova, K., Sandberg, Y., Vojdeman, F. J., Tzenou, T., Chu, C. C., Veronese, S., Mansouri, L., Smedby, K. E., Giudicelli, V., Nguyen-Khac, F., Panagiotidis, P. & 20 others, Juliusson, G., Anagnostopoulos, A., Lefranc, M. P., Trentin, L., Catherwood, M., Montillo, M., Niemann, C. U., Langerak, A. W., Pospisilova, S., Stavroyianni, N., Chiorazzi, N., Oscier, D., Jelinek, D. F., Shanafelt, T., Darzentas, N., Belessi, C., Davi, F., Ghia, P., Rosenquist, R. & Stamatopoulos, K., Mar 23 2018, In : Haematologica. 103, 4, p. e158-e161

Research output: Contribution to journalLetter

B-Cell Chronic Lymphocytic Leukemia
Survival
Therapeutics
2017
7 Citations (Scopus)

Akt inhibitor MK-2206 in combination with bendamustine and rituximab in relapsed or refractory chronic lymphocytic leukemia: Results from the N1087 alliance study

Larsen, J. T., Shanafelt, T. D., Leis, J. F., Laplant, B., Call, T., Pettinger, A., Hanson, C., Erlichman, C., Habermann, T. M., Reeder, C., Nikcevich, D., Bowen, D., Conte, M., Boysen, J., Secreto, C., Lesnick, C., Tschumper, R., Jelinek, D. F., Kay, N. E. & Ding, W. D., 2017, (Accepted/In press) In : American Journal of Hematology.

Research output: Contribution to journalArticle

B-Cell Chronic Lymphocytic Leukemia
Maximum Tolerated Dose
Safety
Febrile Neutropenia
Exanthema
5 Citations (Scopus)

CD49d associates with nodal presentation and subsequent development of lymphadenopathy in patients with chronic lymphocytic leukaemia

Strati, P., Parikh, S. A., Chaffee, K. G., Achenbach, S. J., Slager, S. L., Call, T. G., Ding, W. D., Jelinek, D. F., Hanson, C. A., Kay, N. E. & Shanafelt, T. D., 2017, (Accepted/In press) In : British Journal of Haematology.

Research output: Contribution to journalArticle

B-Cell Chronic Lymphocytic Leukemia
Confidence Intervals
Fluorescence In Situ Hybridization
Lymphoid Leukemia
Cell Adhesion
5 Citations (Scopus)

Chronic lymphocytic leukemia with mutated IGHV4-34 receptors: Shared and distinct immunogenetic features and clinical outcomes

Xochelli, A., Baliakas, P., Kavakiotis, I., Agathangelidis, A., Sutton, L. A., Minga, E., Ntoufa, S., Tausch, E., Yan, X. J., Shanafelt, T., Plevova, K., Boudjogra, M., Rossi, D., Davis, Z., Navarro, A., Sandberg, Y., Vojdeman, F. J., Scarfo, L., Stavroyianni, N., Sudarikov, A. & 42 others, Veronese, S., Tzenou, T., Karan-Djurasevic, T., Catherwood, M., Kienle, D., Chatzouli, M., Facco, M., Bahlo, J., Pott, C., Pedersen, L. B., Mansouri, L., Smedby, K. E., Chu, C. C., Giudicelli, V., Lefranc, M. P., Panagiotidis, P., Juliusson, G., Anagnostopoulos, A., Vlahavas, I., Antic, D., Trentin, L., Montillo, M., Niemann, C., Dohner, H., Langerak, A. W., Pospisilova, S., Hallek, M., Campo, E., Chiorazzi, N., Maglaveras, N., Oscier, D., Gaidano, G., Jelinek, D. F., Stilgenbauer, S., Chouvarda, I., Darzentas, N., Belessi, C., Davi, F., Hadzidimitriou, A., Rosenquist, R., Ghia, P. & Stamatopoulos, K., Sep 1 2017, In : Clinical Cancer Research. 23, 17, p. 5292-5301 10 p.

Research output: Contribution to journalArticle

Immunogenetics
B-Cell Chronic Lymphocytic Leukemia
B-Lymphocytes
Immunoglobulin G
Immunoglobulin M
2016
20 Citations (Scopus)

Clonotypic light chain peptides identified for monitoring minimal residual disease in multiple myeloma without bone marrow aspiration

Bergen, H. R. B. III., Dasari, S., Dispenzieri, A., Mills, J. R., Ramirez-Alvarado, M., Tschumper, R. C., Jelinek, D. F., Barnidge, D. R. & Murray, D. L., Jan 1 2016, In : Clinical Chemistry. 62, 1, p. 243-251 9 p.

Research output: Contribution to journalArticle

Residual Neoplasm
Multiple Myeloma
Bone
Bone Marrow
Light
2015
53 Citations (Scopus)

BCL2 mutations are associated with increased risk of transformation and shortened survival in follicular lymphoma

Correia, C., Schneider, P. A., Dai, H., Dogan, A., Maurer, M. J., Church, A. K., Novak, A. J., Feldman, A. L., Wu, X., Ding, H., Meng, X. W., Cerhan, J. R., Slager, S. L., Macon, W. R., Habermann, T. M., Karp, J. E., Gore, S. D., Kay, N. E., Jelinek, D. F., Witzig, T. E. & 2 others, Nowakowski, G. S. & Kaufmann, S. H., Jan 22 2015, In : Blood. 125, 4, p. 658-667 10 p.

Research output: Contribution to journalArticle

Follicular Lymphoma
Mutation
Lymphoma
Immunoglobulins
Hazards
5 Citations (Scopus)

Cytogenetic prioritization with inclusion of molecular markers predicts outcome in previously untreated patients with chronic lymphocytic leukemia treated with fludarabine or fludarabine plus cyclophosphamide: A long-term follow-up study of the US intergroup phase III trial E2997

Lucas, D. M., Ruppert, A. S., Lozanski, G., Dewald, G. W., Lozanski, A., Claus, R., Plass, C., Flinn, I. W., Neuberg, D. S., Paietta, E. M., Bennett, J. M., Jelinek, D. F., Gribben, J. G., Hussein, M. A., Appelbaum, F. R., Larson, R. A., Moore, D. F., Tallman, M. S., Byrd, J. C. & Grever, M. R., Nov 2 2015, In : Leukemia and Lymphoma. 56, 11, p. 3031-3037 7 p.

Research output: Contribution to journalArticle

B-Cell Chronic Lymphocytic Leukemia
Cytogenetics
Cyclophosphamide
Disease-Free Survival
Survival
25 Citations (Scopus)

Hypogammaglobulinemia in newly diagnosed chronic lymphocytic leukemia: Natural history, clinical correlates, and outcomes

Parikh, S. A., Leis, J. F., Chaffee, K. G., Call, T. G., Hanson, C. A., Ding, W. D., Chanan Khan, A. A., Bowen, D., Conte, M., Schwager, S., Slager, S. L., Van Dyke, D. L., Jelinek, D. F., Kay, N. E. & Shanafelt, T. D., 2015, (Accepted/In press) In : Cancer.

Research output: Contribution to journalArticle

Agammaglobulinemia
B-Cell Chronic Lymphocytic Leukemia
Natural History
Immunoglobulin G
Survival
32 Citations (Scopus)

Not all IGHV3-21 chronic lymphocytic leukemias are equal: Prognostic considerations

Baliakas, P., Agathangelidis, A., Hadzidimitriou, A., Sutton, L. A., Minga, E., Tsanousa, A., Scarfò, L., Davis, Z., Yan, X. J., Shanafelt, T., Plevova, K., Sandberg, Y., Vojdeman, F. J., Boudjogra, M., Tzenou, T., Chatzouli, M., Chu, C. C., Veronese, S., Gardiner, A., Mansouri, L. & 28 others, Smedby, K. E., Pedersen, L. B., Moreno, D., Van Lom, K., Giudicelli, V., Francova, H. S., Nguyen-Khac, F., Panagiotidis, P., Juliusson, G., Angelis, L., Anagnostopoulos, A., Lefranc, M. P., Facco, M., Trentin, L., Catherwood, M., Montillo, M., Geisler, C. H., Langerak, A. W., Pospisilova, S., Chiorazzi, N., Oscier, D., Jelinek, D. F., Darzentas, N., Belessi, C., Davi, F., Ghia, P., Rosenquist, R. & Stamatopoulos, K., Jan 29 2015, In : Blood. 125, 5, p. 856-859 4 p.

Research output: Contribution to journalArticle

B-Cell Chronic Lymphocytic Leukemia
Immunoglobulins
Genes
B-Lymphocytes
Cells
21 Citations (Scopus)

Proteomic detection of immunoglobulin light chain variable region peptides from amyloidosis patient biopsies

Dasari, S., Theis, J. D., Vrana, J. A., Meureta, O. M., Quint, P. S., Muppa, P., Zenka, R. M., Tschumper, R. C., Jelinek, D. F., Davila, J. I., Sarangi, V., Kurtin, P. J. & Dogan, A., Apr 3 2015, In : Journal of Proteome Research. 14, 4, p. 1957-1967 11 p.

Research output: Contribution to journalArticle

Immunoglobulin Light Chains
Biopsy
Amyloidosis
Proteomics
Workflow
24 Citations (Scopus)

The oncogenic transcription factor IRF4 is regulated by a novel CD30/NF-κB positive feedback loop in peripheral T-cell lymphoma

Luchtel, R., Kip, N. S., Xing, X., Zeng, Y., Yang, Z. Z., Lee, J. H., Almada, L. L., Elsawa, S. F., Knudson, R. A., Law, M. E., Ketterling, R. P., Cunningham, J. M., Wu, Y., Maurer, M. J., O'Byrne, M. M., Cerhan, J. R., Slager, S. L., Link, B. K., Porcher, J. C., Grote, D. M. & 5 others, Jelinek, D. F., Dogan, A., Ansell, S. M., Fernandez-Zapico, M. E. & Feldman, A. L., May 14 2015, In : Blood. 125, 20, p. 3118-3127 10 p.

Research output: Contribution to journalArticle

Peripheral T-Cell Lymphoma
T-cells
Transcription Factors
Feedback
interferon regulatory factor-4
2014
4 Citations (Scopus)

Acquired chromosomal anomalies in chronic lymphocytic leukemia patients compared with more than 50,000 quasi-normal participants

Laurie, C. C., Laurie, C. A., Smoley, S. A., Carlson, E. E., Flinn, I., Fridley, B. L., Greisman, H. A., Gribben, J. G., Jelinek, D. F., Nelson, S. C., Paietta, E., Schaid, D. J., Sun, Z., Tallman, M. S., Weinshilboum, R. M., Kay, N. E. & Shanafelt, T. D., 2014, In : Cancer genetics. 207, 1-2, p. 19-30 12 p.

Research output: Contribution to journalArticle

B-Cell Chronic Lymphocytic Leukemia
Uniparental Disomy
Genome-Wide Association Study
Disease-Free Survival
Single Nucleotide Polymorphism
33 Citations (Scopus)

A structurally distinct human mycoplasma protein that generically blocks antigen-antibody union

Grover, R. K., Zhu, X., Nieusma, T., Jones, T., Boero, I., MacLeod, A. S., Mark, A., Niessen, S., Kim, H. J., Kong, L., Assad-Garcia, N., Kwon, K., Chesi, M., Smider, V. V., Salomon, D. R., Jelinek, D. F., Kyle, R. A., Pyles, R. B., Glass, J. I., Ward, A. B. & 2 others, Wilson, I. A. & Lerner, R. A., 2014, In : Science. 343, 6171, p. 656-661 6 p.

Research output: Contribution to journalArticle

Antigens
Antibodies
Proteins
Carrier Proteins
Staphylococcal Protein A
29 Citations (Scopus)

Chronic lymphocytic leukemia in young (≤ 55 years) patients: A comprehensive analysis of prognostic factors and outcomes

Parikh, S. A., Rabe, K. G., Kay, N. E., Call, T. G., Ding, W. D., Schwager, S. M., Bowen, D. A., Conte, M., Jelinek, D. F., Slager, S. L. & Shanafelt, T. D., Jan 1 2014, In : Haematologica. 99, 1, p. 140-147 8 p.

Research output: Contribution to journalArticle

B-Cell Chronic Lymphocytic Leukemia
Survival
Population
Biomarkers
50 Citations (Scopus)

Clinical effect of stereotyped B-cell receptor immunoglobulins in chronic lymphocytic leukaemia: A retrospective multicentre study

Baliakas, P., Hadzidimitriou, A., Sutton, L. A., Minga, E., Agathangelidis, A., Nichelatti, M., Tsanousa, A., Scarfò, L., Davis, Z., Yan, X. J., Shanafelt, T., Plevova, K., Sandberg, Y., Vojdeman, F. J., Boudjogra, M., Tzenou, T., Chatzouli, M., Chu, C. C., Veronese, S., Gardiner, A. & 28 others, Mansouri, L., Smedby, K. E., Pedersen, L. B., van Lom, K., Giudicelli, V., Francova, H. S., Nguyen-Khac, F., Panagiotidis, P., Juliusson, G., Angelis, L., Anagnostopoulos, A., Lefranc, M. P., Facco, M., Trentin, L., Catherwood, M., Montillo, M., Geisler, C. H., Langerak, A. W., Pospisilova, S., Chiorazzi, N., Oscier, D., Jelinek, D. F., Darzentas, N., Belessi, C., Davi, F., Rosenquist, R., Ghia, P. & Stamatopoulos, K., 2014, In : The Lancet Haematology. 1, 2, p. e74-e84

Research output: Contribution to journalArticle

B-Cell Chronic Lymphocytic Leukemia
Multicenter Studies
Immunoglobulins
B-Lymphocytes
Retrospective Studies

Enter protein m

Grover, R. K., Zhu, X., Nieusma, T., Jones, T., Boero, I., MacLeod, A. S., Mark, A., Niessen, S., Kim, H. J., Kong, L., Assad-Garcia, N., Kwon, K., Chesi, M., Smider, V. V., Salomon, D. R., Jelinek, D. F., Kyle, R. A., Pyles, R. B., Glass, J. I., Ward, A. B. & 2 others, Wilson, I. A. & Lerner, R. A., May 1 2014, In : Assay and Drug Development Technologies. 12, 4, p. 204-206 3 p.

Research output: Contribution to journalArticle

Eosinophil purification from human bone marrow

Wong, T. W. & Jelinek, D. F., 2014, In : Methods in molecular biology (Clifton, N.J.). 1178, p. 21-27 7 p.

Research output: Contribution to journalArticle

Eosinophils
Bone Marrow
Parasitic Diseases
Blood Cells
Asthma
24 Citations (Scopus)

Eosinophils regulate peripheral B cell numbers in both mice and humans

Wong, T. W., Doyle, A. D., Lee, J. J. & Jelinek, D. F., Apr 15 2014, In : Journal of Immunology. 192, 8, p. 3548-3558 11 p.

Research output: Contribution to journalArticle

Eosinophils
B-Lymphocytes
Cell Count
Cell Proliferation
Cell Survival
11 Citations (Scopus)

Immunoglobulin heavy variable (IGHV) genes and alleles: new entities, new names and implications for research and prognostication in chronic lymphocytic leukaemia

Xochelli, A., Agathangelidis, A., Kavakiotis, I., Minga, E., Sutton, L. A., Baliakas, P., Chouvarda, I., Giudicelli, V., Vlahavas, I., Maglaveras, N., Bonello, L., Trentin, L., Tedeschi, A., Panagiotidis, P., Geisler, C., Langerak, A. W., Pospisilova, S., Jelinek, D. F., Oscier, D., Chiorazzi, N. & 8 others, Darzentas, N., Davi, F., Ghia, P., Rosenquist, R., Hadzidimitriou, A., Belessi, C., Lefranc, M. P. & Stamatopoulos, K., 2014, In : Immunogenetics. 67, 1, p. 61-66 6 p.

Research output: Contribution to journalArticle

B-Cell Chronic Lymphocytic Leukemia
Directories
Immunogenetics
Names
Immunoglobulins
25 Citations (Scopus)

Monitoring M-proteins in patients with multiple myeloma using heavy-chain variable region clonotypic peptides and LC-MS/MS

Barnidge, D. R., Tschumper, R. C., Theis, J. D., Snyder, M. R., Jelinek, D. F., Katzmann, J. A., Dispenzieri, A. & Murray, D. L., Apr 4 2014, In : Journal of Proteome Research. 13, 4, p. 1905-1910 6 p.

Research output: Contribution to journalArticle

Multiple Myeloma
Peptides
Monitoring
Electrophoresis
Proteins

Monoclonal gammopathies of undetermined significance and smoldering multiple myeloma

Lust, J. A., Jelinek, D. F. & Donovan, K. A., Jan 1 2014, Multiple Myeloma: Diagnosis and Treatment. Springer New York, p. 65-80 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Monoclonal Gammopathy of Undetermined Significance
Multiple Myeloma
Paraproteinemias
Plasma Cells
Waldenstrom Macroglobulinemia
33 Citations (Scopus)

Multiple myeloma dell-derived microvesicles are enriched in CD147 expression and enhance tumor cell proliferation

Arendt, B. K., Walters, D. K., Wu, X., Tschumper, R. C. & Jelinek, D. F., 2014, In : Oncotarget. 5, 14, p. 5686-5699 14 p.

Research output: Contribution to journalArticle

Multiple Myeloma
Cell Proliferation
Cell Line
Neoplasms
Plasma Cells
18 Citations (Scopus)

Phenotyping polyclonal kappa and lambda light chain molecular mass distributions in patient serum using mass spectrometry

Barnidge, D. R., Dasari, S., Ramirez-Alvarado, M., Fontan, A., Willrich, M. A. V., Tschumper, R. C., Jelinek, D. F., Snyder, M. R., Dispenzieri, A., Katzmann, J. A. & Murray, D. L., Nov 7 2014, In : Journal of Proteome Research. 13, 11, p. 5198-5205 8 p.

Research output: Contribution to journalArticle

Molecular mass
Mass spectrometry
Mass Spectrometry
Hypergammaglobulinemia
Immunoglobulin Light Chains
8 Citations (Scopus)

TALEN-mediated genetic tailoring as a tool to analyze the function of acquired mutations in multiple myeloma cells

Wu, X., Blackburn, P. R., Tschumper, R. C., Ekker, S. C. & Jelinek, D. F., 2014, In : Blood Cancer Journal. 4, 5, 210.

Research output: Contribution to journalArticle

Multiple Myeloma
Mutation
Genome
Green Fluorescent Proteins
Plasma Cells
2013
34 Citations (Scopus)

CD147 regulates the expression of MCT1 and lactate export in multiple myeloma cells

Walters, D. K., Arendt, B. K. & Jelinek, D. F., 2013, In : Cell Cycle. 12, 19, p. 3175-3183 9 p.

Research output: Contribution to journalArticle

Multiple Myeloma
Lactic Acid
Cell Line
Down-Regulation
Protons
5 Citations (Scopus)

Genetic characterization of SF3B1 mutations in single chronic lymphocytic leukemia cells

Wu, X., Tschumper, R. C. & Jelinek, D. F., Nov 2013, In : Leukemia. 27, 11, p. 2264-2267 4 p.

Research output: Contribution to journalArticle

U2 Small Nuclear Ribonucleoproteins
Cultured Tumor Cells
Phosphoproteins
B-Cell Chronic Lymphocytic Leukemia
Cohort Studies
55 Citations (Scopus)

Immunogenetics shows that not all MBL are equal: the larger the clone, the more similar to CLL.

Vardi, A., Dagklis, A., Scarfò, L., Jelinek, D. F., Newton, D., Bennett, F., Almeida, J., Rodriguez-Caballero, A., Allgood, S., Lanasa, M., Cortelezzi, A., Orlandi, E., Veronese, S., Montillo, M., Rawstron, A., Shanafelt, T., Orfao, A., Stamatopoulos, K. & Ghia, P., May 30 2013, In : Blood. 121, 22, p. 4521-4528 8 p.

Research output: Contribution to journalArticle

Immunogenetics
Lymphocytosis
B-Cell Chronic Lymphocytic Leukemia
B-Lymphocytes
Clone Cells
1 Citation (Scopus)

Immunoglobulin Structure and Function

Jelinek, D. F. & Li, J. T., Oct 18 2013, Middleton's Allergy: Principles and Practice: Eighth Edition. Elsevier Inc., Vol. 1-2. p. 30-44 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Immunoglobulins
18 Citations (Scopus)

Induction of Malignant Plasma Cell Proliferation by Eosinophils

Wong, T. W., Kita, H., Hanson, C. A., Walters, D. K., Arendt, B. K. & Jelinek, D. F., Jul 22 2013, In : PLoS One. 8, 7, e70554.

Research output: Contribution to journalArticle

myeloma
plasma cells
Cell proliferation
eosinophils
Plasma Cells
62 Citations (Scopus)

Infectious complications among individuals with clinical monoclonal B-cell lymphocytosis (MBL): A cohort study of newly diagnosed cases compared to controls

Moreira, J., Rabe, K. G., Cerhan, J. R., Kay, N. E., Wilson, J. W., Call, T. G., Leis, J. F., Jelinek, D. F., Schwager, S. M., Bowen, D. A., Hanson, C. A., Slager, S. L. & Shanafelt, T. D., Jan 2013, In : Leukemia. 27, 1, p. 136-141 6 p.

Research output: Contribution to journalArticle

Lymphocytosis
B-Cell Chronic Lymphocytic Leukemia
B-Lymphocytes
Cohort Studies
Infection
60 Citations (Scopus)

Long-term repair of T-cell synapse activity in a phase II trial of chemoimmunotherapy followed by lenalidomide consolidation in previously untreated chronic lymphocytic leukemia (CLL).

Shanafelt, T. D., Ramsay, A. G., Zent, C. S., Leis, J. F., Tun, H. W., Call, T. G., LaPlant, B., Bowen, D., Pettinger, A., Jelinek, D. F., Hanson, C. A. & Kay, N. E., May 16 2013, In : Blood. 121, 20, p. 4137-4141 5 p.

Research output: Contribution to journalArticle

T-cells
B-Cell Chronic Lymphocytic Leukemia
Pentostatin
Consolidation
Synapses
5 Citations (Scopus)

Molecular analysis of immunoglobulin genes reveals frequent clonal relatedness in double monoclonal gammopathies

Tschumper, R. C., Dispenzieri, A., Abraham, R. S., Henderson, K. J. & Jelinek, D. F., Apr 2013, In : Blood Cancer Journal. 3, 4, e112.

Research output: Contribution to journalArticle

Immunoglobulin Genes
Paraproteinemias
Light
Immunoglobulin Heavy Chains
Proteins
39 Citations (Scopus)

Ofatumumab-based chemoimmunotherapy is effective and well tolerated in patients with previously untreated chronic lymphocytic leukemia (CLL)

Shanafelt, T., Lanasa, M. C., Call, T. G., Beaven, A. W., Leis, J. F., Laplant, B., Bowen, D., Conte, M., Jelinek, D. F., Hanson, C. A., Kay, N. E. & Zent, C. S., Nov 1 2013, In : Cancer. 119, 21, p. 3788-3796 9 p.

Research output: Contribution to journalArticle

B-Cell Chronic Lymphocytic Leukemia
Retreatment
Pentostatin
Residual Neoplasm
Cyclophosphamide
81 Citations (Scopus)

Phase 2 trial of daily, oral polyphenon e in patients with asymptomatic, Rai stage 0 to II chronic lymphocytic leukemia

Shanafelt, T. D., Call, T. G., Zent, C. S., Leis, J. F., Laplant, B., Bowen, D. A., Roos, M., Laumann, K., Ghosh, A. K., Lesnick, C., Lee, M. J., Yang, C. S., Jelinek, D. F., Erlichman, C. & Kay, N. E., Jan 15 2013, In : Cancer. 119, 2, p. 363-370 8 p.

Research output: Contribution to journalArticle

B-Cell Chronic Lymphocytic Leukemia
Lymphocyte Count
Lymph Nodes
National Cancer Institute (U.S.)
Tea
9 Citations (Scopus)

Purification of functional eosinophils from human bone marrow

Wong, T. W. & Jelinek, D. F., Jan 31 2013, In : Journal of Immunological Methods. 387, 1-2, p. 130-139 10 p.

Research output: Contribution to journalArticle

Eosinophils
Bone Marrow
Chemokine CXCL12
Interleukin-5
Tetradecanoylphorbol Acetate
10 Citations (Scopus)
Cell Line
Cytogenetics
Inhibitory Concentration 50
interferon regulatory factor-4
lenalidomide

Targeting the BAFF/APRIL cytokine network in multiple myeloma

Mihalcik, S. A. & Jelinek, D. F., Jan 1 2013, Advances in Biology and Therapy of Multiple Myeloma: Volume 1: Basic Science. Springer New York, p. 187-202 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Multiple Myeloma
Cytokines
Plasma Cells
B-Lymphocytes
NF-kappa B
25 Citations (Scopus)

The histone methyltransferase MMSET regulates class switch recombination

Pei, H., Wu, X., Liu, T., Yu, K., Jelinek, D. F. & Lou, Z., Jan 15 2013, In : Journal of Immunology. 190, 2, p. 756-763 8 p.

Research output: Contribution to journalArticle

Wolf-Hirschhorn Syndrome
Genetic Recombination
DNA Damage
Inborn Genetic Diseases
Cell Survival
25 Citations (Scopus)

Uncovering the biology of multiple myeloma among African Americans: a comprehensive genomics approach.

Baker, A., Braggio, E. D., Jacobus, S., Jung, S., Larson, D., Therneau, T. M., Dispenzieri, A., Van Wier, S. A., Ahmann, G., Levy, J., Perkins, L., Kim, S., Henderson, K., Vesole, D., Rajkumar, S. V., Jelinek, D. F., Carpten, J. & Fonseca, R., Apr 18 2013, In : Blood. 121, 16, p. 3147-3152 6 p.

Research output: Contribution to journalArticle

Oncology
Genomics
Multiple Myeloma
African Americans
Tumors
2012
15 Citations (Scopus)

Comprehensive assessment of potential multiple myeloma immunoglobulin heavy chain V-D-J intraclonal variation using massively parallel pyrosequencing

Tschumper, R. C., Asmann, Y., Hossain, A., Huddleston, P. M., Wu, X., Dispenzieri, A., Eckloff, B. W. & Jelinek, D. F., Apr 2012, In : Oncotarget. 3, 4, p. 502-513 12 p.

Research output: Contribution to journalArticle

Immunoglobulin Heavy Chains
Multiple Myeloma
Gene Library
Plasma Cells
Complementarity Determining Regions
18 Citations (Scopus)

Increased expression of extracellular matrix metalloproteinase inducer (CD147) in multiple myeloma: Role in regulation of myeloma cell proliferation

Arendt, B. K., Walters, D. K., Wu, X., Tschumper, R. C., Huddleston, P. M., Henderson, K. J., Dispenzieri, A. & Jelinek, D. F., Oct 2012, In : Leukemia. 26, 10, p. 2286-2296 11 p.

Research output: Contribution to journalArticle

CD147 Antigens
Multiple Myeloma
Cell Proliferation
Plasma Cells
Monoclonal Gammopathy of Undetermined Significance
34 Citations (Scopus)

Longitudinal genome-wide analysis of patients with chronic lymphocytic leukemia reveals complex evolution of clonal architecture at disease progression and at the time of relapse

Braggio, E. D., Kay, N. E., Vanwier, S., Tschumper, R. C., Smoley, S., Eckel-Passow, J. E., Sassoon, T., Barrett, M., Van Dyke, D. L., Byrd, J. C., Jelinek, D. F., Shanafelt, T. D. & Fonseca, R., Jul 2012, In : Leukemia. 26, 7, p. 1698-1701 4 p.

Research output: Contribution to journalArticle

Clonal Evolution
Molecular Evolution
Human Genome
B-Cell Chronic Lymphocytic Leukemia
Chromosome Aberrations
84 Citations (Scopus)

Quantitative DNA methylation analysis identifies a single CpG dinucleotide important for ZAP-70 expression and predictive of prognosis in chronic lymphocytic leukemia

Claus, R., Lucas, D. M., Stilgenbauer, S., Ruppert, A. S., Yu, L., Zucknick, M., Mertens, D., Buḧler, A., Oakes, C. C., Larson, R. A., Kay, N. E., Jelinek, D. F., Kipps, T. J., Rassenti, L. Z., Gribben, J. G., Doḧner, H., Heerema, N. A., Marcucci, G., Plass, C. & Byrd, J. C., Jul 10 2012, In : Journal of Clinical Oncology. 30, 20, p. 2483-2491 9 p.

Research output: Contribution to journalArticle

DNA Methylation
B-Cell Chronic Lymphocytic Leukemia
Nucleic Acid Regulatory Sequences
Methylation
DNA Fingerprinting
14 Citations (Scopus)

Survival of patients with clinically identified monoclonal B-cell lymphocytosis (MBL) relative to the age-and sex-matched general population

Shanafelt, T. D., Kay, N. E., Rabe, K. G., Call, T. G., Zent, C. S., Schwager, S. M., Leis, J. F., Jelinek, D. F., Slager, S. L. & Hanson, C. A., Feb 2012, In : Leukemia. 26, 2, p. 373-376 4 p.

Research output: Contribution to journalArticle

Sex Factors
Lymphocytosis
Age Factors
B-Cell Lymphoma
B-Lymphocytes
2011

Biological evaluation of CpG stimulation of normal human B-cells: Implications for B-cell biology and cytogenetic analysis of CLL B-cells

Wu, X., Smoley, S. A., Peterson, M. A., Walters, D. K., Arendt, B. K., Nowakowski, G. S., Van Dyke, D. L., Kay, N. E. & Jelinek, D. F., May 2011, In : British Journal of Haematology. 153, 3, p. 402-405 4 p.

Research output: Contribution to journalArticle

Karyotyping
CpG Islands
Cytogenetic Analysis
B-Cell Chronic Lymphocytic Leukemia
Cytogenetics
67 Citations (Scopus)
Integrin alpha4beta1
B-Cell Lymphoma
Mesenchymal Stromal Cells
Integrins
Apoptosis
17 Citations (Scopus)

Differentiation of chronic lymphocytic leukemia b cells into immunoglobulin secreting cells decreases LEF-1 expression

Gutierrez, A., Arendt, B. K., Tschumper, R. C., Kay, N. E., Zent, C. S. & Jelinek, D. F., Oct 6 2011, In : PLoS One. 6, 10, e26056.

Research output: Contribution to journalArticle

Antibody-Producing Cells
lymphocytic leukemia
Lymphocytes
B-Cell Chronic Lymphocytic Leukemia
immunoglobulins