Darren J Baker, PhD

Assistant Professor

  • 5028 Citations
  • 29 h-Index
20032019
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Research Output 2003 2019

  • 5028 Citations
  • 29 h-Index
  • 47 Article
  • 3 Review article
  • 1 Chapter
  • 1 Letter

Cellular identification and quantification of senescence-associated β-galactosidase activity in vivo

Childs, B. G., Bussian, T. J. & Baker, D. J., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 31-38 8 p. (Methods in Molecular Biology; vol. 1896).

Research output: Chapter in Book/Report/Conference proceedingChapter

Galactosidases
Staining and Labeling
Biological Phenomena
Cell Cycle Checkpoints
Transmission Electron Microscopy
5 Citations (Scopus)

Cellular senescence in brain aging and neurodegenerative diseases: Evidence and perspectives

Baker, D. J. & Petersen, R. C., Apr 2 2018, In : Journal of Clinical Investigation. 128, 4, p. 1208-1216 9 p.

Research output: Contribution to journalReview article

Cell Aging
Brain Diseases
Neurodegenerative Diseases
Cell Cycle Checkpoints
Parkinson Disease
7 Citations (Scopus)

Circulating levels of monocyte chemoattractant protein-1 as a potential measure of biological age in mice and frailty in humans

Yousefzadeh, M. J., Schafer, M. J., Noren Hooten, N., Atkinson, E. J., Evans, M. K., Baker, D. J., Quarles, E. K., Robbins, P. D., Ladiges, W. C., LeBrasseur, N. K. & Niedernhofer, L. J., Jan 1 2018, (Accepted/In press) In : Aging Cell.

Research output: Contribution to journalArticle

Chemokine CCL2
Biomarkers
Progeria
Genetic Engineering
Aortic Valve Stenosis
16 Citations (Scopus)

Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline

Bussian, T. J., Aziz, A., Meyer, C. F., Swenson, B. L., Van Deursen, J. & Baker, D. J., Oct 25 2018, In : Nature. 562, 7728, p. 578-582 5 p.

Research output: Contribution to journalLetter

Neuroglia
Pathology
Cognition
Cell Cycle Proteins
Neurofibrillary Tangles
13 Citations (Scopus)

Age-related decline in BubR1 impairs adult hippocampal neurogenesis

Yang, Z., Jun, H., Choi, C. I., Yoo, K. H., Cho, C. H., Hussaini, S. M. Q., Simmons, A. J., Kim, S., Van Deursen, J., Baker, D. J. & Jang, M-H. D., Jun 1 2017, In : Aging Cell. 16, 3, p. 598-601 4 p.

Research output: Contribution to journalArticle

Neurogenesis
M Phase Cell Cycle Checkpoints
Phosphotransferases
Pathology
Neurons