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Darren J Baker, PhD

  • 6377 Citations
  • 32 Scopus h-Index
20032020
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  • 8 Similar Profiles
Cell Aging Medicine & Life Sciences
M Phase Cell Cycle Checkpoints Medicine & Life Sciences
Aneuploidy Medicine & Life Sciences
Carcinogenesis Medicine & Life Sciences
Phenotype Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Chromosomes Medicine & Life Sciences
Aging of materials Chemical Compounds

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Projects

The contribution of p16-expressing cells to tauopathy

Baker, D. J.

Project: Research project

Research Output 2003 2020

  • 6377 Citations
  • 32 Scopus h-Index
  • 50 Article
  • 4 Review article
  • 1 Chapter
  • 1 Letter

BubR1 allelic effects drive phenotypic heterogeneity in mosaic-variegated aneuploidy progeria syndrome

Sieben, C. J., Jeganathan, K. B., Nelson, G. G., Sturmlechner, I., Zhang, C., Van Deursen, W. H., Bakker, B., Foijer, F., Li, H., Baker, D. J. & Van Deursen, J. M., Jan 2 2020, In : Journal of Clinical Investigation. 130, 1, p. 171-188 18 p.

Research output: Contribution to journal › Article

Open Access
Progeria
Aneuploidy
Sarcopenia
Pathology
Phenotype
1 Citation (Scopus)

Cellular identification and quantification of senescence-associated β-galactosidase activity in vivo

Childs, B. G., Bussian, T. J. & Baker, D. J., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 31-38 8 p. (Methods in Molecular Biology; vol. 1896).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Galactosidases
Staining and Labeling
Biological Phenomena
Cell Cycle Checkpoints
Transmission Electron Microscopy

Cellular Senescence and the Immune System in Cancer

Prieto, L. I. & Baker, D. J., Jan 1 2019, In : Gerontology. 65, 5, p. 505-512 8 p.

Research output: Contribution to journal › Review article

Open Access
Cell Aging
Immune System
Neoplasms
Carcinogenesis
Cell Cycle Checkpoints

Chemotherapy-induced cellular senescence suppresses progression of Notch-driven T-ALL

Zhang, Y., Gundelach, J., Lindquist, L. D., Baker, D. J., Van Deursen, J. & Bram, R. J., Jan 1 2019, In : PloS one. 14, 10, e0224172.

Research output: Contribution to journal › Article

Open Access
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
lymphocytic leukemia
Chemotherapy
T-cells
Cell Aging

Pak2 kinase promotes cellular senescence and organismal aging

Lee, J. S., Mo, Y., Gan, H., Burgess, R. J., Baker, D. J., Van Deursen, J. & Zhang, Z., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 27, p. 13311-13319 9 p.

Research output: Contribution to journal › Article

Open Access
Cell Aging
Phosphotransferases
Heterochromatin
Nucleosomes
Fibroblasts