Arun Kanakkanthara, PhD

  • 446 Citations
  • 12 Scopus h-Index
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  • 3 Similar Profiles
Microtubules Medicine & Life Sciences
Tubulin Medicine & Life Sciences
Excipients Medicine & Life Sciences
Paclitaxel Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences
Mutation Medicine & Life Sciences
Carcinoma Medicine & Life Sciences

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Research Output 2009 2019

  • 446 Citations
  • 12 Scopus h-Index
  • 12 Article
  • 4 Review article
  • 1 Short survey

ZC3H18 specifically binds and activates the BRCA1 promoter to facilitate homologous recombination in ovarian cancer

Kanakkanthara, A., Huntoon, C. J., Hou, X., Zhang, M., Heinzen, E. P., O’Brien, D. R., Oberg, A. L., John Weroha, S., Kaufmann, S. H. & Karnitz, L. M., Dec 1 2019, In : Nature communications. 10, 1, 4632.

Research output: Contribution to journalArticle

Open Access
Homologous Recombination
Ovarian Neoplasms
Messenger RNA
15 Citations (Scopus)

Marine Invertebrate Natural Products that Target Microtubules

Miller, J. H., Field, J. J., Kanakkanthara, A., Owen, J. G., Singh, A. J. & Northcote, P. T., Mar 23 2018, In : Journal of Natural Products. 81, 3, p. 691-702 12 p.

Research output: Contribution to journalReview article

Biological Products
28 Citations (Scopus)

Cyclin A2 is an RNA binding protein that controls Mre11 mRNA translation

Kanakkanthara, A., Jeganathan, K. B., Limzerwala, J. F., Baker, D. J., Hamada, M., Nam, H. J., Van Deursen, W. H., Hamada, N., Naylor, R. M., Becker, N. A., Davies, B. A., Van Ree, J. H., Mer, G., Shapiro, V. M., Maher III, L. J., Katzmann, D. J. & Van Deursen, J., Sep 30 2016, In : Science. 353, 6307, p. 1549-1552 4 p.

Research output: Contribution to journalArticle

Cyclin A2
RNA-Binding Proteins
Protein Biosynthesis
Genetic Recombination
S Phase
3 Citations (Scopus)

Microtubule-stabilizing properties of the avocado-derived toxins (+)-(R)-persin and (+)-(R)-tetrahydropersin in cancer cells and activity of related synthetic analogs

Field, J. J., Kanakkanthara, A., Brooke, D. G., Sinha, S., Pillai, S. D., Denny, W. A., Butt, A. J. & Miller, J. H., Jun 1 2016, In : Investigational New Drugs. 34, 3, p. 277-289 13 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Peloruside A: A lead non-taxoid-site microtubule-stabilizing agent with potential activity against cancer, neurodegeneration, and autoimmune disease

Kanakkanthara, A., Northcote, P. T. & Miller, J. H., Apr 1 2016, In : Natural Product Reports. 33, 4, p. 549-561 13 p.

Research output: Contribution to journalReview article

Autoimmune Diseases