Projects per year
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Cell Death Pathways and Heart Transplant Rejection
Heeger, P. S. & Ting, A.
National Institute of Allergy and Infectious Diseases
6/1/17 → 5/31/22
Project: Research project
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Auto-necroptosis in macrophages
National Institute of Allergy and Infectious Diseases
1/1/17 → 12/31/19
Project: Research project
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Regulation of programmed necrosis by CYLD cleavage.
National Institute of Allergy and Infectious Diseases
4/7/14 → 3/31/15
Project: Research project
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Regulation of TNF Receptor-Mediated Apoptosis
National Institute of Allergy and Infectious Diseases
6/1/08 → 11/30/08
Project: Research project
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Cloning Negative Regulators of TNF Signaling
National Institute of Allergy and Infectious Diseases
4/1/04 → 3/31/06
Project: Research project
Research output
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Human TBK1 deficiency leads to autoinflammation driven by TNF-induced cell death
Taft, J., Markson, M., Legarda, D., Patel, R., Chan, M., Malle, L., Richardson, A., Gruber, C., Martín-Fernández, M., Mancini, G. M. S., van Laar, J. A. M., van Pelt, P., Buta, S., Wokke, B. H. A., Sabli, I. K. D., Sancho-Shimizu, V., Chavan, P. P., Schnappauf, O., Khubchandani, R., Cüceoğlu, M. K. & 6 others, , Aug 19 2021, In: Cell. 184, 17, p. 4447-4463.e20Research output: Contribution to journal › Article › peer-review
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Immune dysregulation in SHARPIN-deficient mice is dependent on CYLD-mediated cell death
Ang, R. L., Chan, M., Legarda, D., Sundberg, J. P., Sun, S. C., Gillespie, V. L., Chun, N., Heeger, P. S., Xiong, H., Lira, S. A. & Ting, A. T., Dec 14 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 50Research output: Contribution to journal › Article › peer-review
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T cell–derived tumor necrosis factor induces cytotoxicity by activating RIPK1-dependent target cell death
Chun, N., Ang, R. L., Chan, M., Fairchild, R. L., Baldwin, W. M., Horwitz, J. K., Gelles, J. D., Chipuk, J. E., Kelliher, M. A., Pavlov, V. I., Li, Y., Homann, D., Heeger, P. S. & Ting, A. T., Dec 22 2021, In: JCI Insight. 6, 24, e148643.Research output: Contribution to journal › Article › peer-review
Open Access -
Correction: A20 protects cells from TNF-induced apoptosis through linear ubiquitin-dependent and -independent mechanisms (Cell Death & Disease, (2019), 10, 10, (692), 10.1038/s41419-019-1937-y)
Priem, D., Devos, M., Druw, S., Martens, A., Slowicka, K., Ting, A. T., Pasparakis, M., Declercq, W., Vandenabeele, P., van Loo, G. & Bertrand, M. J. M., Jan 1 2020, In: Cell Death and Disease. 11, 1, 60.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Reversal of CYLD phosphorylation as a novel therapeutic approach for adult T-cell leukemia/lymphoma (ATLL)
Xu, X., Kalac, M., Markson, M., Chan, M., Brody, J. D., Bhagat, G., Ang, R. L., Legarda, D., Justus, S. J., Liu, F., Li, Q., Xiong, H. & Ting, A. T., Feb 1 2020, In: Cell Death and Disease. 11, 2, 94.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations