Gynecologic Surgery

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Endometrial Neoplasms Medicine & Life Sciences
Ovarian Neoplasms Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Survival Medicine & Life Sciences
Lymph Node Excision Medicine & Life Sciences
Gynecologic Surgical Procedures Medicine & Life Sciences
Hysterectomy Medicine & Life Sciences
Carcinoma Medicine & Life Sciences

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Projects 2002 2020

Poisoning of PARP and Topoisomerase I to Treat Ovarian Cancer

Kaufmann, S. H., Cliby, W. A., Bible, K. C., Goode, E. L., Galanis, E., Knutson, K. L., Hartmann, L. C., Oberg, A. L., Couch, F. J., Fields, A. P., Haluska, P. R. J., Long, H., Bell, D., Keeney, G., Lengyel, E., Keeney, G., Shridhar, V., Cliby, W. A., Goode, E. L., Peng, K., Hartmann, L. C. & Lingle, W. L.

National Institutes of Health

10/1/088/31/20

Project: Research project

Ovarian Neoplasms
alvocidib
Registries
Research
Translational Medical Research
Anti-Mullerian Hormone
Neoplasms
Therapeutics
Growth
Threonine
Ataxia Telangiectasia
Neoplasms
Therapeutics
DNA Damage
Cell Line

Research Output 1992 2019

A phase II, multicenter, open-label trial of OTL38 injection for the intra-operative imaging of folate receptor-alpha positive ovarian cancer

Randall, L. M., Wenham, R. M., Low, P. S., Dowdy, S. C. & Tanyi, J. L., Jan 1 2019, In : Gynecologic oncology.

Research output: Contribution to journalArticle

Folate Receptor 1
Ovarian Neoplasms
Injections
Folic Acid
Safety

BRCA1 deficiency upregulates NNMT, which reprograms metabolism and sensitizes ovarian cancer cells to mitochondrial metabolic targeting agents

Kanakkanthara, A., Kurmi, K., Ekstrom, T. L., Hou, X., Purfeerst, E. R., Heinzen, E. P., Correia, C., Huntoon, C. J., O'Brien, D., Wahner Hendrickson, A. E., Dowdy, S. C., Li, H., Oberg, A. L., Hitosugi, T., Kaufmann, S. H., Weroha, S. J. & Karnitz, L. M., Dec 1 2019, In : Cancer Research. 79, 23, p. 5920-5929 10 p.

Research output: Contribution to journalArticle

Nicotinamide N-Methyltransferase
Ovarian Neoplasms
Up-Regulation
Recombinational DNA Repair
Homologous Recombination

Coiled-Coil and C2 Domain-Containing Protein 1A (CC2D1A) Promotes Chemotherapy Resistance in Ovarian Cancer

Kumar, S., Oien, D. B., Khurana, A., Cliby, W., Hartmann, L., Chien, J. & Shridhar, V., Oct 1 2019, In : Frontiers in Oncology. 9, 986.

Research output: Contribution to journalArticle

Open Access
Ovarian Neoplasms
Drug Therapy
Proteins
Recurrence
Platinum