Both ACTH and indomethacin induce antidiuresis when administered to conscious rats maintained on a sodium-deficient diet for at least two weeks. The present studies show that the ACTH-induced antidiuresis requires the presence of endogenous vasopressin whereas the indomethacin-induced antidiuresis apparently does not. Finally, endogenous vasopressin may play a role in the chronic adaptation to imposed salt states in rats.
|Original language||English (US)|
|Number of pages||5|
|Journal||Annals of the New York Academy of Sciences|
|State||Published - 1982|
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)