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  • Gregory James Gores
2017

PPAR agonists for primary biliary cholangitis

Gossard, A. A. & Gores, G. J., Oct 1 2017, In : The Lancet Gastroenterology and Hepatology. 2, 10, p. 693-694 2 p.

Research output: Contribution to journalComment/debate

1 Scopus citations
2019

Diet Mimicking “Fast Food” Causes Structural Changes to the Retina Relevant to Age-Related Macular Degeneration

Roddy, G. W., Rosa, R. H., Viker, K. B., Holman, B. H., Hann, C. R., Krishnan, A., Gores, G. J., Bakri, S. J. & Fautsch, M. P., Jan 1 2019, (Accepted/In press) In : Current Eye Research.

Research output: Contribution to journalArticle

2017
Open Access
20 Scopus citations

Recent trends in the epidemiology of hepatocellular carcinoma in Olmsted County, Minnesota: A US population-based study

Yang, J. D., Mohammed, H. A., Harmsen, W. S., Enders, F. T., Gores, G. J. & Roberts, L. R., 2017, In : Journal of Clinical Gastroenterology. 51, 8, p. 742-748 7 p.

Research output: Contribution to journalArticle

13 Scopus citations
2016

Anti-GP2 IgA: A biomarker for disease severity and/or cholangiocarcinoma in primary sclerosing cholangitis?

Rizvi, S., Yang, J. D. & Gores, G. J., Sep 1 2016, (Accepted/In press) In : Gut.

Research output: Contribution to journalArticle

2 Scopus citations

Liver capsule: Cholangiocarcinoma (CCA)

Rizvi, S. & Gores, G. J., 2016, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

2 Scopus citations
2018

The circulating microbiome signature and inferred functional metagenomics in alcoholic hepatitis

Puri, P., Liangpunsakul, S., Christensen, J. E., Shah, V., Kamath, P. S., Gores, G. J., Walker, S., Comerford, M., Katz, B., Borst, A., Yu, Q., Kumar, D. P., Mirshahi, F., Radaeva, S., Chalasani, N. P., Crabb, D. W. & Sanyal, A. J., Jan 1 2018, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

29 Scopus citations
2019
1 Scopus citations
2016

A novel, minimally invasive technique for management of peristomal varices

Tabibian, J. H., Abu Dayyeh, B. K., Gores, G. J. & Levy, M. J., Apr 1 2016, In : Hepatology. 63, 4, p. 1398-1400 3 p.

Research output: Contribution to journalArticle

6 Scopus citations
2020

Phenotypic, Transcriptional, and Functional Analysis of Liver Mesenchymal Stromal Cells and Their Immunomodulatory Properties

Taner, T., Abrol, N., Park, W. D., Hansen, M. J., Gustafson, M. P., Lerman, L. O., van Wijnen, A. J., Dietz, A. B., Gores, G. J. & Stegall, M. D., Apr 1 2020, In : Liver Transplantation. 26, 4, p. 549-563 15 p.

Research output: Contribution to journalArticle

2019

GALAD score for hepatocellular carcinoma detection in comparison with liver ultrasound and proposal of Galadus score

Yang, J. D., Addissie, B. D., Mara, K. C., Harmsen, W. S., Dai, J., Zhang, N., Wongjarupong, N., Ali, H. M., Ali, H. A., Hassan, F. A., Lavu, S., Cvinar, J. L., Giama, N. H., Moser, C. D., Miyabe, K., Allotey, L. K., Algeciras-Schimnich, A., Theobald, J. P., Ward, M. M., Nguyen, M. H. & 11 others, Befeler, A. S., Reddy, K. R., Schwartz, M., Harnois, D. M., Yamada, H., Srivastava, S., Rinaudo, J. A., Gores, G. J., Feng, Z., Marrero, J. A. & Roberts, L. R., Mar 2019, In : Cancer Epidemiology Biomarkers and Prevention. 28, 3, p. 531-538 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Intrahepatic Cholangiocarcinoma: Continuing Challenges and Translational Advances

Sirica, A. E., Gores, G. J., Groopman, J. D., Selaru, F. M., Strazzabosco, M., Wei Wang, X. & Zhu, A. X., Apr 2019, In : Hepatology. 69, 4, p. 1803-1815 13 p.

Research output: Contribution to journalReview article

17 Scopus citations
2016

Direct acting antiviral therapy and tumor recurrence after liver transplantation for hepatitis C-associated hepatocellular carcinoma

Yang, J. D., Aqel, B. A., Pungpapong, S., Gores, G. J., Roberts, L. R. & Leise, M. D., 2016, (Accepted/In press) In : Journal of Hepatology.

Research output: Contribution to journalArticle

87 Scopus citations
2017

Impact of country of birth on age at the time of diagnosis of hepatocellular carcinoma in the United States

Yang, J. D., Altekruse, S. F., Nguyen, M. H., Gores, G. J. & Roberts, L. R., Jan 1 2017, In : Cancer. 123, 1, p. 81-89 9 p.

Research output: Contribution to journalArticle

14 Scopus citations
2020

Living Donor Liver Transplantation for Perihilar Cholangiocarcinoma: Outcomes and Complications

Tan, E. K., Rosen, C. B., Heimbach, J. K., Gores, G. J., Zamora-Valdes, D. & Taner, T., Jan 1 2020, (Accepted/In press) In : Journal of the American College of Surgeons.

Research output: Contribution to journalArticle

2016

A Positive TGF-β/c-KIT Feedback Loop Drives Tumor Progression in Advanced Primary Liver Cancer

Rojas, A., Zhang, P., Wang, Y., Foo, W. C., Muñoz, N. M., Xiao, L., Wang, J., Gores, G. J., Hung, M. C. & Blechacz, B., Jun 1 2016, In : Neoplasia (United States). 18, 6, p. 371-386 16 p.

Research output: Contribution to journalArticle

12 Scopus citations
2017
20 Scopus citations
2016

Outcome of transplant-fallout patients with unresectable cholangiocarcinoma

Sio, T. T., Martenson, J. A., Haddock, M. G., Novotny, P. J., Gores, G. J., Alberts, S. R., Miller, R. C., Heimbach, J. K. & Rosen, C. B., Jan 1 2016, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 39, 3, p. 271-275 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

A hippo and fibroblast growth factor receptor autocrine pathway in cholangiocarcinoma

Rizvi, S., Yamada, D., Hirsova, P., Bronk, S. F., Werneburg, N. W., Krishnan, A., Salim, W., Zhang, L., Trushina, E., Truty, M. J. & Gores, G. J., Apr 8 2016, In : Journal of Biological Chemistry. 291, 15, p. 8031-8047 17 p.

Research output: Contribution to journalArticle

41 Scopus citations

Alcohol stimulates macrophage activation through caspase-dependent hepatocyte derived release of CD40L containing extracellular vesicles

Verma, V. K., Li, H., Wang, R., Hirsova, P., Mushref, M., Liu, Y., Cao, S., Contreras, P. C., Malhi, H. M., Kamath, P. S., Gores, G. J. & Shah, V., Mar 1 2016, In : Journal of Hepatology. 64, 3, p. 651-660 10 p.

Research output: Contribution to journalArticle

75 Scopus citations

Prognostic Significance of the Histologic Response of Perihilar Cholangiocarcinoma to Preoperative Neoadjuvant Chemoradiation in Liver Explants

Lehrke, H. D., Heimbach, J. K., Wu, T. T., Jenkins, S. M., Gores, G. J., Rosen, C. B. & Mounajjed, T., Jan 8 2016, (Accepted/In press) In : American Journal of Surgical Pathology.

Research output: Contribution to journalArticle

9 Scopus citations

Lipid-Induced Signaling Causes Release of Inflammatory Extracellular Vesicles from Hepatocytes

Hirsova, P., Ibrahim, S. C., Krishnan, A., Verma, V. K., Bronk, S. F., Werneburg, N. W., Charlton, M. R., Shah, V., Malhi, H. M. & Gores, G. J., Apr 1 2016, In : Gastroenterology. 150, 4, p. 956-967 12 p.

Research output: Contribution to journalArticle

116 Scopus citations
53 Scopus citations
2017

Proapoptotic signaling induced by deletion of receptor-interacting kinase 1 and TNF receptor-associated factor 2 results in liver carcinogenesis

Hirsova, P., Guicciardi, M. E. & Gores, G. J., Sep 1 2017, In : Hepatology. 66, 3, p. 983-985 3 p.

Research output: Contribution to journalComment/debate

4 Scopus citations
2018

cHCC-CCA: Consensus terminology for primary liver carcinomas with both hepatocytic and cholangiocytic differentation

Brunt, E., Aishima, S., Clavien, P. A., Fowler, K., Goodman, Z., Gores, G., Gouw, A., Kagen, A., Klimstra, D., Komuta, M., Kondo, F., Miksad, R., Nakano, M., Nakanuma, Y., Ng, I., Paradis, V., Nyun Park, Y., Quaglia, A., Roncalli, M., Roskams, T. & 14 others, Sakamoto, M., Saxena, R., Sempoux, C., Sirlin, C., Stueck, A., Thung, S., Tsui, W. M. S., Wang, X. W., Wee, A., Yano, H., Yeh, M., Zen, Y., Zucman-Rossi, J. & Theise, N., Jul 2018, In : Hepatology. 68, 1, p. 113-126 14 p.

Research output: Contribution to journalArticle

56 Scopus citations

Non-alcoholic steatohepatitis pathogenesis: Sublethal hepatocyte injury as a driver of liver inflammation

Ibrahim, S. C., Hirsova, P. & Gores, G. J., May 1 2018, In : Gut. 67, 5, p. 963-972 10 p.

Research output: Contribution to journalArticle

42 Scopus citations
2016

Implications of CA19-9 elevation for survival, staging, and treatment sequencing in intrahepatic cholangiocarcinoma: A national cohort analysis

Bergquist, J. R., Ivanics, T., Storlie, C., Groeschl, R. T., Tee, M. C., Habermann, E. B., Smoot, R. L., Kendrick, M. L., Farnell, M. B., Roberts, L. R., Gores, G. J., Nagorney, D. M. & Truty, M., Sep 15 2016, In : Journal of Surgical Oncology. 114, 4, p. 475-482 8 p.

Research output: Contribution to journalArticle

28 Scopus citations
2017

Biliary tract instillation of a SMAC mimetic induces TRAIL-dependent acute sclerosing cholangitis-like injury in mice

Guicciardi, M. E., Krishnan, A., Bronk, S. F., Hirsova, P., Griffith, T. S. & Gores, G. J., Jan 5 2017, In : Cell Death and Disease. 8, 1, e2535.

Research output: Contribution to journalArticle

5 Scopus citations
2018

Targeting senescent cholangiocytes and activated fibroblasts with B-cell lymphoma-extra large inhibitors ameliorates fibrosis in multidrug resistance 2 gene knockout (Mdr2−/−) mice

Moncsek, A., Al-Suraih, M. S., Trussoni, C. E., O'Hara, S. P., Splinter, P. L., Zuber, C., Patsenker, E., Valli, P. V., Fingas, C. D., Weber, A., Zhu, Y., Tchkonia, T., Kirkland, J. L., Gores, G. J., Müllhaupt, B., La Russo, N. F. & Mertens, J. C., Jan 1 2018, In : Hepatology. 67, 1, p. 247-259 13 p.

Research output: Contribution to journalArticle

34 Scopus citations
2019

The transcription factor ETS1 promotes apoptosis resistance of senescent cholangiocytes by epigenetically up-regulating the apoptosis suppressor BCL2L1

O'Hara, S. P., Splinter, P. L., Trussoni, C. E., Guicciardi, M. E., Splinter, N. P., Al Suraih, M. S., Nasser-Ghodsi, N., Stollenwerk, D., Gores, G. J. & LaRusso, N. F., Jan 1 2019, In : Journal of Biological Chemistry. 294, 49, p. 18698-18713 16 p.

Research output: Contribution to journalArticle

1 Scopus citations

Ccne1 Overexpression Causes Chromosome Instability in Liver Cells and Liver Tumor Development in Mice

Aziz, K., Limzerwala, J. F., Sturmlechner, I., Hurley, E., Zhang, C., Jeganathan, K. B., Nelson, G., Bronk, S., Fierro Velasco, R. O., van Deursen, E. J., O'Brien, D. R., Kocher, J-P., Youssef, S. A., van Ree, J. H., de Bruin, A., van den Bos, H., Spierings, D. C. J., Foijer, F., van de Sluis, B., Roberts, L. R. & 3 others, Gores, G. J., Li, H. & Van Deursen, J., Jul 1 2019, In : Gastroenterology. 157, 1, p. 210-226.e12

Research output: Contribution to journalArticle

5 Scopus citations
2018

Macrophages contribute to the pathogenesis of sclerosing cholangitis in mice

Guicciardi, M. E., Trussoni, C. E., Krishnan, A., Bronk, S. F., Lorenzo Pisarello, M. J., O'Hara, S. P., Splinter, P. L., Gao, Y., Vig, P., Revzin, A., La Russo, N. F. & Gores, G. J., Jan 1 2018, (Accepted/In press) In : Journal of Hepatology.

Research output: Contribution to journalArticle

21 Scopus citations
2020

Diabetes Is Associated With Increased Risk of Hepatocellular Carcinoma in Patients With Cirrhosis From Nonalcoholic Fatty Liver Disease

Yang, J. D., Ahmed, F., Mara, K. C., Addissie, B. D., Allen, A. M., Gores, G. J. & Roberts, L. R., Mar 1 2020, In : Hepatology. 71, 3, p. 907-916 10 p.

Research output: Contribution to journalArticle

4 Scopus citations
2017

Emerging pharmacologic therapies for primary sclerosing cholangitis

Cheung, A. C., Lazaridis, K. N., La Russo, N. F. & Gores, G. J., Mar 2 2017, (Accepted/In press) In : Current Opinion in Gastroenterology.

Research output: Contribution to journalArticle

6 Scopus citations

Epigenetics in the Primary Biliary Cholangitis and Primary Sclerosing Cholangitis

Cheung, A. C., La Russo, N. F., Gores, G. J. & Lazaridis, K. N., May 1 2017, In : Seminars in Liver Disease. 37, 2, p. 159-174 16 p.

Research output: Contribution to journalArticle

9 Scopus citations
2016

Performance of magnetic resonance elastography in primary sclerosing cholangitis

Eaton, J. E., Dzyubak, B., Venkatesh, S. K., Smyrk, T. C., Gores, G. J., Ehman, R. L., La Russo, N. F., Gossard, A. A. & Lazaridis, K. N., Jun 1 2016, In : Journal of Gastroenterology and Hepatology (Australia). 31, 6, p. 1184-1190 7 p.

Research output: Contribution to journalArticle

37 Scopus citations
2017

Primary Sclerosing Cholangitis. What the Gastroenterologist and Hepatologist Needs to Know

Gossard, A. A. & Gores, G. J., 2017, (Accepted/In press) In : Clinics in Liver Disease.

Research output: Contribution to journalArticle

5 Scopus citations
2016

Vigilancia del colangiocarcinoma en pacientes con colangitis esclerosante primaria: ¿es efectiva y está justificada?

Razumilava, N. & Gores, G. J., Nov 1 2016, In : Clinical Liver Disease. 8, p. S20-S24

Research output: Contribution to journalReview article

2019

Translation to Practice: Accelerating the Cycle of Innovation to Impact

Anderson, J. R., Chung, T. D. Y., Clark, L., Weis, J. A., Danielsen, A. J., Khosla, S., Gores, G. J. & Badley, A. D., Jan 1 2019, In : Mayo Clinic proceedings.

Research output: Contribution to journalReview article

1 Scopus citations
2017

Improved performance of serum alpha-fetoprotein for hepatocellular carcinoma diagnosis in hcv cirrhosis with normal alanine transaminase

Yang, J. D., Dai, J., Singal, A. G., Gopal, P., Addissie, B. D., Nguyen, M. H., Befeler, A. S., Reddy, K. R., Schwartz, M., Harnois, D. M., Yamada, H., Gores, G. J., Feng, Z., Marrero, J. A. & Roberts, L. R., Jul 1 2017, In : Cancer Epidemiology Biomarkers and Prevention. 26, 7, p. 1085-1092 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Prohibitin 1 suppresses liver cancer tumorigenesis in mice and human hepatocellular and cholangiocarcinoma cells

Fan, W., Yang, H., Liu, T., Wang, J., Li, T. W. H., Mavila, N., Tang, Y., Yang, J., Peng, H., Tu, J., Annamalai, A., Noureddin, M., Krishnan, A., Gores, G. J., Martínez-Chantar, M. L., Mato, J. M. & Lu, S. C., 2017, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

21 Scopus citations

Epidemiology, risk factors, and outcomes of infections in patients undergoing liver transplantation for hilar cholangiocarcinoma

Ramanan, P., Cummins, N. W., Wilhelm, M. P., Heimbach, J. K., Dierkhising, R., Kremers, W. K., Rosen, C. B., Gores, G. J. & Razonable, R. R., 2017, (Accepted/In press) In : Clinical Transplantation.

Research output: Contribution to journalArticle

3 Scopus citations

Platelet-derived growth factor regulates YAP transcriptional activity via Src family kinase dependent tyrosine phosphorylation

Smoot, R., Werneburg, N. W., Sugihara, T., Hernandez, M. C., Yang, L., Mehner, C., Graham, R., Bronk, S. F., Truty, M. & Gores, G. J., 2017, (Accepted/In press) In : Journal of Cellular Biochemistry.

Research output: Contribution to journalArticle

14 Scopus citations
2019

Animal models of cholangiocarcinoma

Loeuillard, E., Fischbach, S. R., Gores, G. J. & Rizvi, S., May 1 2019, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1865, 5, p. 982-992 11 p.

Research output: Contribution to journalReview article

7 Scopus citations
2016

Chapter 115B - Liver transplantation for nonhepatocellular malignant disease

Burns, J. M., Rosen, C. B., Heimbach, J. K. & Gores, G. J., Dec 2 2016, Blumgart's Surgery of the Liver, Biliary Tract and Pancreas: Sixth Edition. Elsevier Inc., Vol. 2-2. p. 1791-1800.e2

Research output: Chapter in Book/Report/Conference proceedingChapter

2020

Systemic therapies for intrahepatic cholangiocarcinoma

Kelley, R. K., Bridgewater, J., Gores, G. J. & Zhu, A. X., Feb 2020, In : Journal of hepatology. 72, 2, p. 353-363 11 p.

Research output: Contribution to journalReview article

2 Scopus citations
2018

Emerging Technologies for the Diagnosis of Perihilar Cholangiocarcinoma

Rizvi, S., Eaton, J., Yang, J. D., Chandrasekhara, V. & Gores, G. J., May 1 2018, In : Seminars in Liver Disease. 38, 2, p. 160-169 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Fibroblast Growth Factor Receptor Inhibition for Cholangiocarcinoma: Looking Through a Door Half-Opened

Rizvi, S. & Gores, G. J., Jan 1 2018, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

2017

Serum extracellular vesicles contain protein biomarkers for primary sclerosing cholangitis and cholangiocarcinoma

Arbelaiz, A., Azkargorta, M., Krawczyk, M., Santos-Laso, A., Lapitz, A., Perugorria, M. J., Erice, O., Gonzalez, E., Jimenez-Agüero, R., Lacasta, A., Ibarra, C., Sanchez-Campos, A., Jimeno, J. P., Lammert, F., Milkiewicz, P., Marzioni, M., Macias, R. I. R., Marin, J. J. G., Patel, T., Gores, G. J. & 5 others, Martinez, I., Elortza, F., Falcon-Perez, J. M., Bujanda, L. & Banales, J. M., Oct 2017, In : Hepatology. 66, 4, p. 1125-1143 19 p.

Research output: Contribution to journalArticle

62 Scopus citations
2016

Effects of Age, Sex, Body Weight, and Quantity of Alcohol Consumption on Occurrence and Severity of Alcoholic Hepatitis

Translational Research and Evolving Alcoholic Hepatitis Treatment Consortium & Translational Research and Evolving Alcoholic Hepatitis Treatment Consortium, Dec 1 2016, In : Clinical Gastroenterology and Hepatology. 14, 12, p. 1831-1838.e3

Research output: Contribution to journalArticle

19 Scopus citations