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  Integration of Genomic and Clinical Data to Enhance Subtyping of Colon Cancer

  Sinicrope, F. A.

  National Cancer Institute

  Project: Research project

  • Colonic Neoplasms
  • Consensus
  • Gene Expression
  • Survival
  • Learning

• Measurement of surface lung tissue using ultrasound

  Zhang, X.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Lung
  • Interstitial Lung Diseases
  • Fibrosis
  • Longitudinal Studies
  • Clinical Studies

• Activation of the Secretin Receptor as a Strategy for the Treatment of Heart Failure

  Miller, L. J.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • secretin receptor
  • Treatment Failure
  • Heart Failure
  • Secretin
  • CHO Cells

• Natural History of Shoulder Pathology in Wheelchair Users

  Morrow, M. (. M. & Morrow, M. (. M.

  Eunice Kennedy Shriver National Institute of Child Health and Human Development

  Project: Research project

  • Wheelchairs
  • Pathology
  • Magnetic resonance imaging
  • Health
  • Environmental technology

• Small molecule mitochondria-targeted therapeutics for Huntingtons Disease

  Trushina, E. D.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • Huntington Disease
  • Mitochondria
  • Neuroprotection
  • Bacterial Artificial Chromosomes
  • Oxidative Stress

• Phase 3 stem cell transplant for light chain amyloidosis

  Gertz, M., Gertz, M. & Kinney, L.

  National Cancer Institute

  Project: Research project

  • Amyloidosis
  • Stem Cells
  • Light
  • Transplants
  • Amyloid

• The Role of Microglia in Epilepsy

  Wu, L. & Kinney, L.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • Microglia
  • Epilepsy
  • Seizures
  • Glutamic Acid
  • Chemotactic Factors

• Regulation of Necroptosis and inflammation

  Lou, Z.

  National Cancer Institute

  Project: Research project

  • AMP-Activated Protein Kinases
  • Inflammation
  • Neoplasms
  • Ubiquitination
  • Gene Deletion

• Factors Influencing Access and Utilization of Genetic Prenatal Care Services Among Women from Underserved Populations

  Allyse, M.

  National Human Genome Research Institute

  Project: Research project

  • utilization
  • genetic services
  • health
  • national minority
  • diagnostic services

• Brain Neurotropic Growth Factor Delivery to Prevent and Treat Alzheimer?s Disease

  Kanekiyo, T.

  National Institute on Aging

  Project: Research project

  • Liposomes
  • Cell-Penetrating Peptides
  • Transferrin
  • Intercellular Signaling Peptides and Proteins
  • Brain

• Epigenetic Heterogeneity as a Driver of Liver Disease and Cancer

  Robertson, K. D.

  National Institute on Alcohol Abuse and Alcoholism

  Project: Research project

  • Liver Neoplasms
  • Epigenomics
  • Liver Diseases
  • Hepatocellular Carcinoma
  • Hepacivirus

• Universal positive allosteric modulators of CCK1R without intrinsic agonist activity for the treatment of obesity

  Miller, L. J.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • CHO Cells
  • Obesity
  • cholecystokinin 58
  • Cholecystokinin Receptors
  • Small Molecule Libraries

• Astrocytic function in DBS for essential tremor

  Chang, S.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • Essential Tremor
  • Tremor
  • Astrocytes
  • Adenosine
  • Optogenetics

• Analyzing and Interpreting PRO-CTCAE with CTCAE and Other Clinical Data to Characterize Drug Tolerability

  Dueck, A. & Dueck, A.

  National Cancer Institute

  Project: Research project

  • Patient Reported Outcome Measures
  • Terminology
  • Clinical Trials
  • Pharmaceutical Preparations
  • Research Personnel

• Targeted chemotherapy delivery and capture

  Oklu, R.

  National Institute of Biomedical Imaging and Bioengineering

  Project: Research project

  • Drug Therapy
  • Pharmaceutical Preparations
  • Drug-Eluting Stents
  • Drug Liberation
  • Drug-Related Side Effects and Adverse Reactions

• Post-transcriptional Regulation of Satellite Cell Function

  Doles, J.

  National Institute of Arthritis and Musculoskeletal and Skin Diseases

  Project: Research project

  • Tristetraprolin
  • Messenger RNA
  • Muscle Cells
  • Adult Stem Cells
  • Stem Cells

• ST8Sia6 expression on tumors inhibits the immune response

  Shapiro, V. M.

  National Cancer Institute

  Project: Research project

  • Sialic Acid Binding Immunoglobulin-like Lectins
  • Neoplasms
  • N-Acetylneuraminic Acid
  • Growth
  • Transferases

• Using Label-free Ultrasound Angio-Morphometry Analysis for Improving Ultrasound Specificity in Breast Cancer Detection and Treatment Monitoring

  Alizad, A. & Fatemi, M.

  National Cancer Institute

  Project: Research project

  • Labels
  • Ultrasonics
  • Biopsy
  • Monitoring
  • Chemotherapy

• The effect of endogenous GLP-1 secretion on islet function in vivo

  Vella, A.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • Glucagon-Like Peptide 1
  • Fasting
  • Glucagon-Like Peptide-1 Receptor
  • Glucagon
  • Glucose

• Structure and Function of New Blood Vessels

  Mukhopadhyay, D.

  National Cancer Institute

  Project: Research project

  • Vascular Endothelial Growth Factor Receptor
  • Vascular Endothelial Growth Factor Receptor-1
  • Vascular Endothelial Growth Factor A
  • Vascular Endothelial Growth Factor Receptor-2
  • Endothelial Cells

• ER? repurposes EZH2 to suppress oncogenic NF?B signaling in TNBC

  Hawse, J. R.

  National Cancer Institute

  Project: Research project

  • Estrogen Receptor beta
  • Triple Negative Breast Neoplasms
  • Breast Neoplasms
  • Neoplasms
  • Cell Line

• Role of LDLR in regulating metabolism of Apolipoprotein E and Amyloid-beta

  Kim, J.

  Project: Research project

• Detection of somatic, subclonal and mosaic CNVs from sequencing

  Abyzov, A.

  National Cancer Institute

  Project: Research project

  • Whole Genome Sequencing
  • Medicine
  • Genome
  • Neoplasms
  • Human Genetics

• Dominantly Inherited Alzheimer Network

  Carrasquillo, M. M.

  Project: Research project

• Identification and characterization of AD risk networks using multi-dimensional omics data

  Carrasquillo, M. M.

  Project: Research project

• ALZHEIMERS DISEASE

  Carrasquillo, M. M.

  Project: Research project

• Quantitative Ultrasound Imaging Biomarkers of Crohn's Disease

  Chen, S. D., Chen, S. D. & Bruining, D. H.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • Crohn Disease
  • Ultrasonography
  • Biomarkers
  • Fibrosis
  • Comb and Wattles

• Advanced MR Imaging and Image Analytics as a Precision Medicine Tool to Manage ADPKD

  Kline, T.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • autosomal dominant polycystic kidney disease
  • precision medicine
  • image analysis
  • kidneys
  • biomarkers

• Use of Chemically Modified RNA to Enhance Bone Healing

  Evans, C. H.

  National Institute of Arthritis and Musculoskeletal and Skin Diseases

  Project: Research project

  • bone morphogenetic proteins
  • bones
  • RNA
  • gene therapy
  • sheep

• SHARED SCIENTIFIC COMPUTING RESOURCE

  Khoor, A. & Leof, E. B.

  National Institutes of Health

  Project: Research project

• Chemically produced neural progenitors as a delivery vehicle for anti-glioma therapy

  Quinones-Hinojosa, A.

  National Cancer Institute

  Project: Research project

  • Glioma
  • Tropism
  • Bone Morphogenetic Protein 4
  • Neural Stem Cells
  • Stem Cells

• Modifier Genes that Influence Age at Onset or Protect Against Development of Alzheimer's Disease (AD)

  Carrasquillo, M. M.

  Project: Research project

• CANCER AND LEUKEMIA GROUP B

  Diasio, R. B. & Diasio, R. B.

  National Institutes of Health, National Cancer Institute

  Project: Research project

  • Leukemia
  • Historically Controlled Study
  • Neoplasms
  • Lung Neoplasms
  • Population Control

• Minimally Invasive Molecular Approaches for the Detection of Barrett?s Esophagus and Esophageal Adenocarcinoma

  Iyer, P. G. & Kisiel, J. B.

  National Cancer Institute

  Project: Research project

  • Adenocarcinoma Of Esophagus
  • Porifera
  • Adenocarcinoma
  • Gastroesophageal Reflux
  • Genetic Markers

• HEALTHY AGING AND SENILE DEMENTIA

  Carrasquillo, M. M.

  Project: Research project

• Phase 1 Study of VSV-hIFN-B for the Treatment of Hepatocellular Carcinoma

  Borad, M. J., Borad, M. J. & Borad, M. J.

  U.S. Food and Drug Administration, National Institutes of Health

  Project: Research project

  • Vesicular Stomatitis
  • Hepatocellular Carcinoma
  • Interferon-beta
  • Cercopithecine Herpesvirus 1
  • Viruses

• Integration of germline and tumor genomes in CLL

  Braggio, E. D. & Slager, S. L.

  National Cancer Institute

  Project: Research project

  • B-Cell Chronic Lymphocytic Leukemia
  • Single Nucleotide Polymorphism
  • Genome
  • Neoplasms
  • Genome-Wide Association Study

• CTRA Software Solution for Fracture Risk Assessment of Axial Skeleton

  Yaszemski, M. J.

  National Institute on Aging

  Project: Research project

  • Skeleton
  • Risk Assessment
  • Software
  • Tomography
  • Neoplasm Metastasis

• Understanding the Bidirectional Relationship between Depression and Heart Failure

  Bobo, W. V.

  Agency for Healthcare Research and Quality

  Project: Research project

  • Heart Failure
  • Depression
  • Major Depressive Disorder
  • Electronic Health Records
  • Data Mining

• Novel genetic modifiers of C9orf72 and Tau toxicity

  Fryer, J. D. & Petrucelli, L.

  National Institute on Aging

  Project: Research project

  • Collaborative Cross Mice
  • Dependovirus
  • Frontotemporal Dementia With Motor Neuron Disease
  • Frontotemporal Lobar Degeneration
  • Validation Studies

• EHR-Based Strategies to Improve Outcomes in Familial Hypercholesterolemia

  Kullo, I. J.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Hyperlipoproteinemia Type II
  • Lipoprotein(a)
  • Inborn Genetic Diseases
  • LDL Cholesterol
  • Cardiovascular Diseases

• A network platform to connect drug response and prognosis phenotypes for cancers

  Li, H.

  Project: Research project

• Administrative Core

  Kantarci, K. M., Boeve, B. F., Dickson, D. W. & Knopman, D. S.

  National Institute on Aging

  Project: Research project

  • Frontotemporal Lobar Degeneration
  • dementia
  • Organized Financing
  • Biomarkers
  • African Americans

• Overcoming Drug Resistance in Multiple Myeloma

  Bergsagel, L., Stewart, A. K., Kumar, S. K., Meurice, N. & Meurice, N.

  Project: Research project

• Core A: Administrative Core

  Gores, G. J., Vile, R. G., Leof, E. B., Mandrekar, S. J., Torbenson, M. & Alberts, S. R.

  National Cancer Institute

  Project: Research project

  • biostatistics
  • Fibrolamellar hepatocellular carcinoma
  • research programs
  • Receptor, Fibroblast Growth Factor, Type 2
  • bioinformatics

• Capturing the molecular complexity of Alzheimer's disease through the lens of RNA binding proteins

  Li, H.

  National Institute on Aging

  Project: Research project

  • Microtubule-Associated Proteins
  • RNA-Binding Proteins
  • Lenses
  • Alzheimer Disease
  • Tauopathies

• Injectable and Moldable Composite Bone Scaffolds for Spinal Fusion

  Yaszemski, M. J.

  National Institute of Arthritis and Musculoskeletal and Skin Diseases

  Project: Research project

  • bones
  • fusion
  • composite materials
  • propylene
  • animal models

• Molecular pathobiology of soluble TREM2 in Alzheimer's disease.

  Bu, G. D.

  National Institute on Aging

  Project: Research project

  • Alzheimer disease type 2
  • Myeloid Cells
  • Genome-Wide Association Study
  • Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy
  • Cerebrospinal Fluid

• Protecting the Confidentiality of Participants in Studies of Alzheimer's Disease and Related Dementias by Replacing Face Imagery in MRI

  Schwarz, C.

  Project: Research project

• Enhancing Adaptations to Exercise

  Lanza, I. R.

  National Institute on Aging

  Project: Research project

  • Inflammation
  • Skeletal Muscle
  • Adipose Tissue
  • Muscles
  • Abdominal Subcutaneous Fat