Rochester, MN

Projects

Projects per year 1989 2002 2009 2010 2011 2014 2015 2016 2017 2018 2019 2020 2021 2025

• 29 Not started
• 321 Active
• 971 Finished

Projects per year

Search results

• Involution-based biomarkers of breast cancer risk

  Degnim, A. C., Radisky, D. C. & Sherman, M. E.

  National Cancer Institute

  9/1/20 → 5/31/22

  Project: Research project

  • Breast Neoplasms 100%
  • Breast Diseases 88%
  • Biomarkers 83%
  • Breast 43%
  • Milk 26%

• A new model for spatio-temporal coupling of bone formation and bone resorption governed by osteoclasts

  Mishina, Y., Park, D. & Weivoda, M.

  National Institute of Arthritis and Musculoskeletal and Skin Diseases

  9/1/20 → 8/31/22

  Project: Research project

  • Osteoclasts 100%
  • Temporal Bone 78%
  • Bone Resorption 72%
  • Osteogenesis 69%
  • Osteoblasts 66%

• Does obesity exacerbate age-related cognitive decline via senescence?

  Jurk, D.

  National Institute on Aging

  9/10/20 → 5/31/22

  Project: Research project

  • Obesity 100%
  • Cognitive Dysfunction 96%
  • Brain 30%
  • Lipidomics 20%
  • Healthy Aging 19%

• Discovery of Novel Pharmaceutical Agents for Skeletal Muscle Atrophy

  Adams, C., Ebert, S. & Talley, J. J.

  National Institute of Arthritis and Musculoskeletal and Skin Diseases

  9/10/20 → 8/31/22

  Project: Research project

  • Muscular Atrophy 100%
  • Skeletal Muscle 64%
  • Pharmaceutical Preparations 28%
  • Glucose Intolerance 19%
  • Obesity 19%

• A Randomized Controlled Trial of Sequential Bilateral Accelerated Theta Burst Stimulation in Adolescents with Suicidal Ideation Associated with Major Depressive Disorder

  Croarkin, P. E.

  National Institute of Mental Health, NATIONAL INSTITUTE OF MENTAL HEALTH

  9/10/20 → 8/31/22

  Project: Research project

  • Suicidal Ideation 100%
  • Psychological Inhibition 87%
  • Major Depressive Disorder 83%
  • gamma-Aminobutyric Acid 63%
  • Suicide 61%

• Improving Cardiac Rehabilitation outcomes through mobile case management (iCARE)

  Olson, T. P.

  National Institute of Nursing Research

  9/14/20 → 7/31/22

  Project: Research project

  • Cardiac Rehabilitation 100%
  • Case Management 66%
  • Telemedicine 20%
  • Cardiovascular Diseases 13%
  • Referral and Consultation 8%

• Non-pharmacological Options in postoperative Hospital-based And Rehabilitation pain Management (NOHARM) pragmatic clinical trial

  Cheville, A. L. & Tilburt, J. C.

  National Institute on Aging

  9/15/20 → 8/31/22

  Project: Research project

• Role of PAPP-A in Pulmonary Fibrosis

  Conover, C. A.

  National Institute on Aging

  9/15/20 → 5/31/22

  Project: Research project

  • Pregnancy-Associated Plasma Protein-A 100%
  • Pulmonary Fibrosis 57%
  • Idiopathic Pulmonary Fibrosis 27%
  • Somatomedins 18%
  • Transforming Growth Factors 17%

• Role of RBBP4/p300 Complex in Recovery from therapy induced DNA damage in glioblastoma

  Kitange, G.

  National Cancer Institute

  9/19/20 → 6/30/22

  Project: Research project

  • DNA Damage 100%
  • Glioblastoma 94%
  • Temozolomide 80%
  • Radiation 57%
  • Retinoblastoma Protein 48%

• Chronic Alcohol Exposure and Pathophysiology of Alzheimer's Disease.

  Choi, D. S. & Trushina, E. D.

  National Institute on Aging

  9/30/20 → 5/31/22

  Project: Research project

  • Alcohols 100%
  • Alzheimer Disease 73%
  • Alcohol Drinking 66%
  • Sex Characteristics 17%
  • Alcoholism 16%

• Independent brain metabolic patterns in Progressive Supranuclear Palsy

  Ali, F.

  National Institute of Neurological Disorders and Stroke

  9/30/20 → 5/31/22

  Project: Research project

  • Progressive Supranuclear Palsy 100%
  • Positron-Emission Tomography 24%
  • Brain 24%
  • Parkinsonian Disorders 19%
  • Tauopathies 11%

• Airway Structural Cells and Corticosteroid Resistance in Asthma

  Britt, R. J.

  National Heart, Lung, and Blood Institute

  12/20/20 → 11/30/22

  Project: Research project

  • Adrenal Cortex Hormones 100%
  • Asthma 89%
  • Smooth Muscle 29%
  • Inflammation 21%
  • Pediatrics 21%

• Pathogenesis of Primary Biliary Cholangitis

  Lazaridis, K. N.

  National Institute of Diabetes and Digestive and Kidney Diseases

  12/21/20 → 11/30/22

  Project: Research project

  • Biliary Liver Cirrhosis 100%
  • Autoimmune Diseases 12%
  • Liver Diseases 11%
  • Exposome 5%

• Genetic Biomarkers for Risk of CLL Progression among high-count MBLs

  Kleinstern, G., Slager, S. L. & Slager, S. L.

  National Cancer Institute

  1/1/21 → 12/31/22

  Project: Research project

  • Lymphocytosis 100%
  • B-Cell Chronic Lymphocytic Leukemia 67%
  • B-Lymphocytes 67%
  • Biomarkers 51%
  • Drive 19%

• Optimization of Drug Efflux and Brain Clearance to Improve CED of Targeted Therapy to H3K27M DMG

  Daniels, D.

  Alex's Lemonade Stand Foundation for Childhood Cancer

  1/1/21 → …

  Project: Research project

  • Blood-Brain Barrier 100%
  • Brain Stem Neoplasms 49%
  • Pharmaceutical Preparations 49%
  • Convection 49%
  • Child 44%

• ERβ repurposes EZH2 to suppress oncogenic NFκB signaling in TNBC

  Hawse, J. R.

  National Cancer Institute

  1/1/21 → 12/31/22

  Project: Research project

  • Estrogen Receptor beta 100%
  • Triple Negative Breast Neoplasms 80%
  • Drug Therapy 16%
  • Breast Neoplasms 14%
  • Neoplasms 13%

• Exploiting a Metabolic Dependency of PARPinhibitor-Resistant Ovarian Cancer

  Kanakkanthara, A.

  Ovarian Cancer Research Alliance

  1/1/21 → 12/31/23

  Project: Research project

  • Poly(ADP-ribose) Polymerase Inhibitors 100%
  • Ovarian Neoplasms 60%
  • Nicotinamide-Nucleotide Adenylyltransferase 51%
  • Homologous Recombination 21%
  • Platinum 9%

• Epigenetic dysregulation in diabetic enteric neuropathy

  Ordog, T.

  National Institute of Diabetes and Digestive and Kidney Diseases

  1/1/21 → 12/31/22

  Project: Research project

  • Intestinal Pseudo-Obstruction 100%
  • Gastroparesis 96%
  • Diabetic Neuropathies 83%
  • Epigenomics 62%
  • Nitric Oxide 54%

• Relating Molecular Subgroups of Endometriosis-Associated Ovarian Cancers to Survival and Risk

  Goode, E. L. & Goode, E. L.

  National Cancer Institute

  1/13/21 → 12/31/22

  Project: Research project

  • Ovarian Neoplasms 100%
  • Endometriosis 86%
  • taxane 35%
  • Neoplasms 26%
  • Survival 20%

• Overcoming immune checkpoint inhibition with therapeutic plasma exchange and radiotherapy in melanoma

  Orme, J. & Park, S. S.

  National Cancer Institute

  2/5/21 → 1/31/23

  Project: Research project

  • Melanoma 100%
  • Plasma Exchange 91%
  • Radiotherapy 52%
  • Psychological Inhibition 49%
  • Radiosurgery 41%

• Flortaucipir PET and histopathology in frontotemporal lobar degeneration and Alzheimer?s disease

  Josephs, K. A. & Whitwell, J. L.

  National Institute of Neurological Disorders and Stroke

  2/15/21 → 1/31/24

  Project: Research project

  • 7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indole 100%
  • Frontotemporal Lobar Degeneration 62%
  • Autopsy 16%
  • Ligands 9%
  • Neurofibrillary Tangles 7%

• Assessment of Metabolites Among Asymptomatic Precursor and Malignant Monoclonal Gammopathies

  Gonsalves, W.

  National Cancer Institute

  3/1/21 → 2/28/23

  Project: Research project

  • Paraproteinemias 100%
  • Plasma Cells 94%
  • Multiple Myeloma 69%
  • Smoldering Multiple Myeloma 58%
  • Monoclonal Gammopathy of Undetermined Significance 39%

• Novel multipronged Immunovirotherapy Approach for GBM Treatment

  Galanis, E.

  National Cancer Institute

  3/1/21 → 2/28/23

  Project: Research project

  • Janus Kinase Inhibitors 100%
  • Oncolytic Viruses 99%
  • Glioblastoma 93%
  • Toll-Like Receptor 2 90%
  • Critical Pathways 73%

• Role of pH-mediated metabolic reprogramming in β cell failure in Type 2 Diabetes Mellitus

  Matveyenko, A. V., Romero, M. F. & Matveyenko, A. V.

  National Institute of Diabetes and Digestive and Kidney Diseases

  4/1/21 → 2/28/23

  Project: Research project

  • Type 2 Diabetes Mellitus 100%
  • Cellular Reprogramming 65%
  • Glucose 17%
  • Sodium-Bicarbonate Symporters 15%
  • Ion Pumps 14%

• Stathmin-2 and TDP-43 neurodegeneration in Alzheimer?s and multi-etiology dementias

  Josephs, K. A. & Prudencio, M.

  National Institute of Neurological Disorders and Stroke

  4/1/21 → 3/31/24

  Project: Research project

  • Stathmin 100%
  • Alzheimer Disease 78%
  • Dementia 48%
  • Frontotemporal Lobar Degeneration 40%
  • Neurofibrillary Tangles 17%

• What is N? Towards operationalizing neurodegeneration in Alzheimer's and related dementias

  Graff-Radford, J., Mielke, M. M. & Vemuri, P. D.

  National Institute on Aging

  4/15/21 → 3/31/24

  Project: Research project

  • Alzheimer Disease 100%
  • Cognitive Dysfunction 77%
  • Cerebrovascular Disorders 73%
  • Dementia 71%
  • Amyloid 67%

• Identifying targetable mechanisms of TMEM38B/TRIC-B in liver fibrosis

  Maiers, J.

  National Center for Advancing Translational Sciences

  5/15/21 → 5/14/22

  Project: Research project

  • Hepatic Stellate Cells 100%
  • Liver Cirrhosis 51%
  • Procollagen 49%
  • Fibrosis 27%
  • Osteoblasts 14%

• Novel Strategies to Treat Diffuse Midline Glioma with CAR T Cell Therapy

  Vile, R. G.

  National Cancer Institute

  6/1/21 → 5/31/22

  Project: Research project

  • Chimeric Antigen Receptors 100%
  • CD40 Ligand 54%
  • Glioma 45%
  • Cell- and Tissue-Based Therapy 42%
  • T-Lymphocytes 40%

• Deve inlopment of A High-Throughput Screen for Identification of Targeted Therapies in Brainstem Tumors with the H3K27M Mutation

  Daniels, D.

  National Institute of Neurological Disorders and Stroke

  6/1/21 → 5/31/23

  Project: Research project

  • Brain Stem Neoplasms 100%
  • Diffuse Intrinsic Pontine Glioma 76%
  • Mutation 60%
  • Glioma 42%
  • Neoplasms 34%

• Sensitizing Ovarian Cancer To PARP inhibitor and platinum treatment

  Lou, Z.

  National Cancer Institute

  6/1/21 → 5/31/22

  Project: Research project

  • Homologous Recombination 100%
  • Poly(ADP-ribose) Polymerase Inhibitors 76%
  • Platinum 65%
  • Ovarian Neoplasms 60%
  • DNA Damage 30%

• NAD+ metabolism in PARP inhibitor resistance of ovarian cancer

  Kanakkanthara, A.

  National Cancer Institute

  6/15/21 → 5/31/22

  Project: Research project

  • Poly(ADP-ribose) Polymerase Inhibitors 100%
  • Nicotinamide-Nucleotide Adenylyltransferase 72%
  • Ovarian Neoplasms 66%
  • NAD 48%
  • Homologous Recombination 37%

• A randomized control trial of G-POEM for gastroparesis to assess feasibility, safety, efficacy and physiological mechanisms

  Camilleri, M. & Pasricha, P.

  National Institute of Diabetes and Digestive and Kidney Diseases

  6/15/21 → 5/31/22

  Project: Research project

  • Pyloromyotomy 100%
  • Gastroparesis 82%
  • Antral 33%
  • Gastric Emptying 25%
  • Safety 20%

• Cause and therapeutic impact of DNA-protein crosslink repair defect in myeloid leukemias

  Kaufmann, S. H. & Machida, Y.

  National Cancer Institute

  7/1/21 → 6/30/22

  Project: Research project

  • Myeloid Leukemia 100%
  • DNA 86%
  • Acute Myeloid Leukemia 71%
  • Topotecan 51%
  • Proteins 41%

• Germline and Somatic Genomic Studies in CLL Minorities

  Braggio, E. D. & Slager, S. L.

  National Cancer Institute

  7/1/21 → 6/30/22

  Project: Research project

  • B-Cell Chronic Lymphocytic Leukemia 100%
  • African Americans 58%
  • Population 7%
  • Genome-Wide Association Study 5%

• Role of Small Extracellular Vesicles in Beta Cell Failure and Autoimmunity in Type 1 Diabetes Mellitus

  Javeed, N.

  National Institute of Diabetes and Digestive and Kidney Diseases

  8/1/21 → 7/31/22

  Project: Research project

  • Extracellular Vesicles 100%
  • Type 1 Diabetes Mellitus 72%
  • Antigen Presentation 15%
  • Research Personnel 10%
  • Insulin 9%

• 2021 Physiology in Focus: The Role of Sex Hormones, Genetics and Gender in Physiology & Medicine

  Garovic, V. D. & Yanes Cardozo, L.

  National Heart, Lung, and Blood Institute

  8/1/21 → 7/31/22

  Project: Research project

  • physiology 100%
  • medicine 46%
  • trainee 37%
  • gender 34%
  • poster 28%

• Evaluating the role of the novel apoptosis inhibitor TRAILshort, in maintaining HIV persistence

  Badley, A. D.

  National Institute of Allergy and Infectious Diseases

  8/2/21 → 7/31/22

  Project: Research project

  • T-Lymphocytes 100%
  • HIV 98%
  • Apoptosis 53%
  • TNF-Related Apoptosis-Inducing Ligand Receptors 52%
  • T-Cell Antigen Receptor 37%

• PD-L1 Intracellular RNA binding function regulates immune suppression

  Mutter, R.

  National Cancer Institute

  9/1/21 → 8/31/22

  Project: Research project

  • Ligands 100%
  • RNA 62%
  • Triple Negative Breast Neoplasms 39%
  • Immunity 21%
  • TOR Serine-Threonine Kinases 14%

• Center of Innovation for Brain Tumor Therapeutics

  Bindra, R., Galanis, E., Omuro, A. & Sarkaria, J. N.

  National Cancer Institute

  9/1/21 → 8/31/22

  Project: Research project

  • Glioblastoma 100%
  • Brain Neoplasms 97%
  • Neoplasms 32%
  • Therapeutics 31%
  • Pharmaceutical Preparations 27%

• The Vascular, Autonomic, and Myocardial Phenotypes in Women with Myocardial Infarction due to Spontaneous Coronary Artery Dissection

  Tweet, M.

  National Heart, Lung, and Blood Institute

  9/1/21 → 8/31/22

  Project: Research project

  • Spontaneous Coronary Artery Dissection 100%
  • National Heart, Lung, and Blood Institute (U.S.) 30%
  • Myocardial Infarction 25%
  • Phenotype 23%
  • Blood Vessels 22%

• Collaborative Research: SCH: A Causal AI Digital Twin Framework to Transform Intensive Care Delivery

  Schulte, P., Gajic, O. & Dong, Y.

  National Science Foundation

  9/1/21 → 8/31/25

  Project: Research project

  • Digital twin 100%
  • Intensive care units 64%
  • Mathematical transformations 52%
  • Health 50%
  • Medicine 48%

• Targeting Protease Activated Receptor 1 for Repair of the Injured Spinal Cord

  Scarisbrick, I. A.

  National Institute of Neurological Disorders and Stroke

  9/1/21 → 8/31/22

  Project: Research project

  • Spinal Cord Injuries 100%
  • Spinal Cord Regeneration 91%
  • PAR-1 Receptor 89%
  • Neuroprotection 87%
  • Neuroglia 73%

• INvestigative Kyphoplasty Efficacy and Safety Trial (INKTEST)

  Jarvik, J. & Kallmes, D. F.

  National Institute of Arthritis and Musculoskeletal and Skin Diseases

  9/1/21 → 8/31/22

  Project: Research project

  • Kyphoplasty 100%
  • Vertebroplasty 89%
  • Safety 22%
  • Economic Inflation 18%
  • Randomized Controlled Trials 16%

• Role of endothelium in pathogenesis of cerebral amyloid angiopathy

  Katusic, Z. S.

  National Institute on Aging

  9/1/21 → 6/30/22

  Project: Research project

  • Cerebral Amyloid Angiopathy 100%
  • Endothelium 49%
  • Blood Vessels 14%
  • Cerebrovascular Trauma 10%
  • Endothelial Cells 9%

• Polygenic Risk of Disease in Populations of Diverse Ancestry

  Kullo, I. J. & Schaid, D. J.

  National Human Genome Research Institute

  9/8/21 → 6/30/22

  Project: Research project

  • Population 100%
  • Coronary Disease 85%
  • Hypercholesterolemia 38%
  • Datasets 30%
  • Medicine 28%

• Mayo Clinic HeartShare Clinical Center

  Borlaug, B. A. & Redfield, M. M.

  National Heart, Lung, and Blood Institute

  9/10/21 → 7/31/22

  Project: Research project

  • Data Science 100%
  • Machine learning 40%
  • Clinical research 25%
  • Biomarkers 23%
  • Hemodynamics 22%

• Epigenetic mechanisms of carcinogenesis by Parvimonas micra, an oral cavity commensal turned colon cancer pathogen

  Gounari, F., Khazaie, K. & Staley, C.

  National Cancer Institute

  9/13/21 → 8/31/22

  Project: Research project

  • Colorectal Neoplasms 100%
  • DNA Methylation 62%
  • Colonic Neoplasms 60%
  • Epigenomics 58%
  • Mouth 57%

• Liver Cirrhosis Network: Clinical Research Center - Mayo Clinic

  Shah, V. & Simonetto, D.

  National Institute of Diabetes and Digestive and Kidney Diseases

  9/13/21 → 8/31/22

  Project: Research project

  • Fibrosis 100%
  • Liver Cirrhosis 66%
  • Extracellular Traps 54%
  • Telomere 42%
  • Simvastatin 34%

• Enabling rapid and effective stroke thrombectomy procedures from a Transradial approach: Combining introducer sheath, guide catheter, and distal access catheter into a single device.

  Kallmes, D. F.

  National Institute of Neurological Disorders and Stroke

  9/15/21 → 8/31/22

  Project: Research project

  • Thrombectomy 100%
  • Catheters 49%
  • Stroke 39%
  • Equipment and Supplies 32%
  • Thoracic Aorta 26%

• Outcomes for CLL patients treated with novel therapy

  Kay, N. E. & Shanafelt, T. D.

  National Cancer Institute

  9/15/21 → 8/31/22

  Project: Research project

  • PCI 32765 100%
  • B-Cell Chronic Lymphocytic Leukemia 64%
  • Rituximab 51%
  • T-Lymphocytes 20%
  • Immunotherapy 11%