Mayo Clinic

Projects

Projects per year 1973 2021

• 45 Active
• 777 Not started
• 1574 Finished

Projects per year

Search results

• Drug Eluting Embolization Coils for Improved Treatment of Intracranial Aneurysms

  Kadirvel, R. D. & Kadirvel, R. D.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • Intracranial Aneurysm 100%
  • Aneurysm 97%
  • genipin 51%
  • Pharmaceutical Preparations 38%
  • Safety 32%

• Drug eluting injectable biomaterials for next generation chemoembolization

  Oklu, R.

  National Cancer Institute

  Project: Research project

  • liver 100%
  • cancer 97%
  • chemotherapy 93%
  • tumors 86%
  • drugs 84%

• Drug repurposing study for tobacco dependence treatment using zebrafish

  Klee, E. W. & Kinney, L.

  National Institute on Drug Abuse

  Project: Research project

  • Tobacco Use Disorder 100%
  • Zebrafish 95%
  • Drug Repositioning 95%
  • Varenicline 36%
  • Tobacco 34%

• Dynamics of Cytotoxic Lymphocyte-Glial Interactions During Acute Meningitis

  Kang, S. & Kinney, L.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • Lymphocytic choriomeningitis virus 100%
  • Neuroglia 56%
  • Meningitis 52%
  • Central Nervous System 47%
  • T-Lymphocytes 39%

• Dysregulation of Glutamine Metabolism in the Pathogenesis of Multiple Myeloma

  Gonsalves, W.

  National Cancer Institute

  Project: Research project

  • Multiple Myeloma 100%
  • Glutamine 92%
  • Monoclonal Gammopathy of Undetermined Significance 40%
  • Plasma Cells 35%
  • Metabolomics 23%

• EARLY INTERVENTION/CHRONIC OBSTRUCTIVE PULMONARY DISEASE

  Scanlon, P. D.

  Project: Research project

  • Chronic Obstructive Pulmonary Disease 100%
  • Tobacco Products 52%
  • Multicenter Studies 48%
  • Smokers 47%
  • Clinical Trials 36%

• Early prediction of colorectal liver metastases treatment response with ultrasound microvessel imaging

  Song, P.

  Project: Research project

• Ect2 Function in Lung Adenocarcinoma Initiation and Maintenance

  Justilien, V.

  National Cancer Institute

  Project: Research project

  • Adenocarcinoma of Lung 100%
  • Epithelial Cells 83%
  • Maintenance 56%
  • Neoplastic Stem Cells 43%
  • Ribosomal RNA 39%

• EFFECT OF CA ANTAGONISTS ON FOCAL ISCHEMIA &SEIZURES

  Meyer, F.

  Project: Research project

• Effects of Microengineered Interactions on Liver-Specific Gene Expression

  Revzin, A. & Kinney, L.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • Liver 100%
  • Hepatocytes 87%
  • Gene Expression 81%
  • Cell Culture Techniques 63%
  • Human Embryonic Stem Cells 50%

• Effects of senescence to Alzheimer's disease pathology

  Baker, D. J.

  National Institute on Aging

  Project: Research project

  • Neurodegenerative Diseases 100%
  • Pathology 68%
  • Alzheimer Disease 66%
  • Preliminary Data 31%
  • Drive 29%

• Efficacy of self-management of sedative therapy by ventilated ICU patients

  Chlan, L.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Self-Management 100%
  • Hypnotics and Sedatives 98%
  • Intensive Care Units 75%
  • Artificial Respiration 32%
  • Nurses 29%

• EHR-Based Strategies to Improve Outcomes in Familial Hypercholesterolemia

  Kullo, I. J.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Hyperlipoproteinemia Type II 100%
  • Lipoprotein(a) 46%
  • Inborn Genetic Diseases 34%
  • LDL Cholesterol 34%
  • Cardiovascular Diseases 27%

• Enabling Comparative Effectiveness Research in Silent Brain Infarction Through Natural Language Processing and Big Data

  Liu, H. D.

  Project: Research project

  • Brain Infarction 100%
  • Stroke 26%
  • Natural Language Processing 25%
  • Comparative Effectiveness Research 19%
  • Leukoencephalopathies 17%

• Enabling Independent Living by Expanding Access to Home-Based Pulmonary Rehabilitation

  Benzo, R. P.

  Project: Research project

  • Lung Diseases 100%
  • Rehabilitation 61%
  • Lung 34%
  • National Heart, Lung, and Blood Institute (U.S.) 21%
  • Independent Living 16%

• Endocytic Trafficking of ADCs in GBM cancer stem-like cells

  Sarkaria, J. N.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • ABT-414 100%
  • Neoplastic Stem Cells 64%
  • Glioblastoma 64%
  • Immunoconjugates 26%
  • Recycling 16%

• Engineered microtumor arrays for development of combination therapies

  Copland, J. A. I.

  Project: Research project

  • Melanoma 100%
  • Heterografts 77%
  • Standard of Care 33%
  • Neoplasms 33%
  • Nude Mice 32%

• Engineering an HIV-resistant immune system for HIV cure

  Fadel, H.

  National Institute of Allergy and Infectious Diseases

  Project: Research project

  • HIV-1 100%
  • Immune System 77%
  • HIV 74%
  • Hematopoietic Stem Cells 30%
  • Genetic Therapy 21%

• Engineering selective inhibition of metalloproteinases by tissue inhibitors of metalloproteinases (R01 GM132100 RESUB - *TIMPs)

  Radisky, E. S.

  National Institute of General Medical Sciences

  Project: Research project

  • Tissue Inhibitor of Metalloproteinases 100%
  • Matrix Metalloproteinases 85%
  • Metalloproteases 51%
  • Matrix Metalloproteinase Inhibitors 32%
  • Crotalus adamanteus proteinase II 12%

• Engineering tissue inhibitor of metalloproteinases-2 (TIMP-2) for triple negative breast cancer therapy

  Radisky, E. S.

  National Cancer Institute

  Project: Research project

  • Protein 100%
  • Biological Marker 54%
  • X-Ray Crystallography 50%
  • Drug 31%
  • Surface 19%

• Enhanced, EHR-facilitated Cancer Symptom Control (E2C2) Pragmatic Clinical Trial

  Cheville, A. L.

  National Cancer Institute

  Project: Research project

  • Pragmatic Clinical Trials 100%
  • Touch 50%
  • Patient Reported Outcome Measures 41%
  • Neoplasms 38%
  • Self-Management 26%

• Enhanced endothelialization of nanomatrix coated flow diverter for intracranial aneurysms

  Kadirvel, R. D.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • Intracranial Aneurysm 100%
  • Aneurysm 90%
  • Endothelial Cells 75%
  • Monocytes 33%
  • Ruptured Aneurysm 24%

• Enhancing Adaptations to Exercise

  Lanza, I. R.

  National Institute on Aging

  Project: Research project

  • Inflammation 100%
  • Skeletal Muscle 67%
  • Adipose Tissue 59%
  • Muscles 51%
  • Abdominal Subcutaneous Fat 20%

• ENHANCING CARDIOPOIETIC REGENERATION FOR ISCHEMIC CARDIOMYOPATHY

  Terzic, A.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Stem Cells 100%
  • Cardiomyopathies 94%
  • Regeneration 73%
  • Cell- and Tissue-Based Therapy 55%
  • Heart Failure 42%

• Enhancing Corticosteroid Sensitivity in Neonatal and Pediatric Lung Disease

  Britt, R. J.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Adrenal Cortex Hormones 100%
  • Lung Diseases 95%
  • Pediatrics 71%
  • Smooth Muscle 43%
  • Asthma 40%

• Enhancing Respiratory Motor Function after Spinal Cord Injury

  Mantilla, C. B. & Sieck, G. C.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Diaphragm 100%
  • Spinal Cord Injuries 82%
  • Motor Neurons 47%
  • Brain-Derived Neurotrophic Factor 32%
  • Muscles 29%

• Enhancing Treatment Response by Leveraging STAT5-OLIG2 signaling in GBM

  Tran, N.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • Glioblastoma 100%
  • Glioma 57%
  • epidermal growth factor receptor VIII 56%
  • Temozolomide 32%
  • Stem Cells 32%

• Enterochromaffin cell mechanotransduction and mechanosensitive serotonin release depend on calcium signaling downstream of Piezo2 activation

  Beyder, A.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • Enterochromaffin Cells 100%
  • Calcium Signaling 56%
  • Serotonin 47%
  • Irritable Bowel Syndrome 43%
  • Gastrointestinal Diseases 13%

• Eosinophil Regulation of Pulmonary IL-13 Levels

  Jacobsen, E. & Kinney, L.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Eosinophils 100%
  • Interleukin-13 73%
  • Asthma 53%
  • Lung 51%
  • Pulmonary Eosinophilia 40%

• Epidemiology and Genomics of Ovarian Clear Cell Carcinoma

  Goode, E. L.

  National Cancer Institute

  Project: Research project

  • Genomics 100%
  • Carcinoma 94%
  • Epidemiology 77%
  • Ovarian Epithelial Carcinoma 29%
  • Neoplasms 28%

• EPIDEMIOLOGY OF ALZHEIMER DISEASE IN A TOTAL POPULATION

  Knopman, D. S.

  National Institute on Aging

  Project: Research project

  • Dementia 100%
  • Alzheimer Disease 84%
  • Epidemiology 73%
  • Saints 47%
  • Population 43%

• Epidermal growth factor receptor signaling in glioma

  Uhm, J.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • ErbB Receptors 100%
  • Glioma 96%
  • Receptor Protein-Tyrosine Kinases 20%
  • erbB-1 Genes 12%
  • Mentors 11%

• Epigenetic dysregulation in diabetic enteric neuropathy

  Ordog, T.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • Intestinal Pseudo-Obstruction 100%
  • Gastroparesis 98%
  • Epigenomics 83%
  • Diabetic Neuropathies 83%
  • Gastric Emptying 82%

• Epigenetic Heterogeneity as a Driver of Liver Disease and Cancer

  Robertson, K. D.

  National Institute on Alcohol Abuse and Alcoholism

  Project: Research project

  • Hepatocellular Carcinoma 100%
  • Epigenomics 97%
  • Liver Neoplasms 94%
  • Liver Diseases 81%
  • Hepacivirus 30%

• Epigenetic Mechanisms Underlying Hepatitis C-Induced Hepatocarcinogenesis

  Robertson, K. D.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • Hepacivirus 100%
  • Hepatitis C 99%
  • Hepatocellular Carcinoma 86%
  • Epigenomics 84%
  • Liver Cirrhosis 49%

• Epigenetic Modulation of the Epiphyseal Growth Plate to Treat Pediatric Limb Deformities

  Larson, A. N.

  Project: Research project

• Epigenetic Regulation in Primary Sclerosing Cholangitis

  Huebert, R. C.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • Sclerosing Cholangitis 100%
  • Enhancer of Zeste Homolog 2 Protein 91%
  • Hepatic Stellate Cells 73%
  • Acetylation 62%
  • Epigenomics 61%

• Epigenomic Biomarkers of HIV-Associated Cancers in Nigeria

  Roberts, L. R.

  Project: Research project

  • HIV 100%
  • Epigenomics 87%
  • Biomarkers 50%
  • Hepatocellular Carcinoma 44%
  • Uterine Cervical Neoplasms 41%

• ER? repurposes EZH2 to suppress oncogenic NF?B signaling in TNBC

  Hawse, J. R.

  National Cancer Institute

  Project: Research project

  • Estrogen Receptor beta 100%
  • Triple Negative Breast Neoplasms 94%
  • Breast Neoplasms 17%
  • Neoplasms 13%
  • Cell Line 12%

• ESTROGEN, DIET, GENETICS AND ENDOMETRIAL CANCER

  Petersen, G. M.

  Project: Research project

• Evaluation of germline mutations associated with risk of nephrolithiasis

  Haley, W. E.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • Nephrolithiasis 100%
  • Kidney Calculi 93%
  • Germ-Line Mutation 63%
  • Causality 35%
  • Mutation 16%

• Evaluation of Patient-Matched Primary and Metastatic Samples to Identify and Vali

  Eckel-Passow, J. E. & Kinney, L.

  National Cancer Institute

  Project: Research project

  • Neoplasms 100%
  • Neoplasm Metastasis 95%
  • Tertiary Prevention 57%
  • Therapeutics 44%
  • Survival 42%

• Evidence Based Encounter Decision Aid for Elderly Patients to Promote Shared Decision Making on Treatment Choice in End Stage Renal Disease

  Thorsteinsdottir, B. (.

  Project: Research project

• Exceptional Aging: Identifying Modifiers of Alzheimer's Disease Trajectories

  Vemuri, P. D.

  Project: Research project

  • Adenosine Diphosphate 100%
  • Alzheimer Disease 78%
  • Amyloid 63%
  • Protective Factors 54%
  • Cognitive Dysfunction 41%

• Expanding access to CBT for childhood anxiety disorders via smart phones

  Whiteside, S. P. & Kinney, L.

  National Institute of Mental Health

  Project: Research project

  • Smartphone 100%
  • Anxiety Disorders 85%
  • Cognitive Behavioral Therapy 84%
  • Mentoring 58%
  • Anxiety 38%

• Expanding insights into FTD disease mechanisms

  Petrucelli, L.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • Frontotemporal Lobar Degeneration 100%
  • 3'-N-acetylfusarochromanone 15%
  • Biomarkers 12%
  • Progranulins 9%
  • Naphazoline 9%

• Exploring the Unmeasured Risk and Treating the Untreated Prognostic Factor: Towards Candidate Optimization in Heart and Lung Transplant

  Kennedy, C.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Self-Management 100%
  • Transplants 68%
  • Heart 61%
  • Lung 52%
  • Mentors 38%

• Extracellular alpha-synuclein in Parkinson's Disease

  McLean, P. J., Kinney, L. & Kinney, L.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • alpha-Synuclein 100%
  • Macroautophagy 12%
  • Disease Progression 9%
  • Lewy Bodies 5%
  • Neurons 5%

• Extracellular vesicle RNA signaling in liver tumor microenvironment

  Patel, T. C.

  National Cancer Institute

  Project: Research project

  • Extracellular Vesicles 100%
  • Tumor Microenvironment 81%
  • RNA 57%
  • Liver 40%
  • Liver Neoplasms 31%

• EXTRAMURAL RESEARCH FACILITIES IMPROVEMENT PROGRAM

  Burnett, J. C. J.

  National Center for Research Resources

  Project: Research project

  • National Institutes of Health 100%
  • research facilities 99%
  • image analysis 90%
  • funding 24%
  • principal investigators 18%