Women-specific factors to consider in risk, diagnosis and treatment of cardiovascular disease

Ronée E. Harvey, Kirsten E. Coffman, Virginia M. Miller

Research output: Contribution to journalReview article

45 Scopus citations

Abstract

In the era of individualized medicine, gaps in knowledge remain about sex-specific risk factors, diagnostic and treatment options that might reduce mortality from cardiovascular disease (CVD) and improve outcomes for both women and men. In this review, contributions of biological mechanisms involving the sex chromosomes and the sex hormones on the cardiovascular system will be discussed in relationship to the female-specific risk factors for CVD: hypertensive disorders of pregnancy, menopause and use of hormonal therapies for contraception and menopausal symptoms. Additionally, sex-specific factors to consider in the differential diagnosis and treatment of four prevalent CVDs (hypertension, stroke, coronary artery disease and congestive heart failure) will be reviewed with emphasis on areas where additional research is needed.

Original languageEnglish (US)
Pages (from-to)239-257
Number of pages19
JournalWomen's Health
Volume11
Issue number2
DOIs
StatePublished - Mar 1 2015

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Keywords

  • estrogen
  • menopause
  • pregnancy
  • sex chromosomes

ASJC Scopus subject areas

  • Medicine(all)

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