Women, kidney disease, and pregnancy

Andrew Smyth, Milan Radovic, Vesna D. Garovic

Research output: Contribution to journalReview article

21 Scopus citations

Abstract

Several glomerular diseases may occur in women of childbearing age. Pregnancy in such patients should be planned when the disease has been in remission for a minimum of 6 months to minimize maternal and fetal complications. Immunosuppressive agents should be optimized before conception to include those that are safe for pregnancy. The complexity of medical management when caring for these patients calls for a multidisciplinary team approach consisting of a nephrologist, rheumatologist, obstetrician, and pharmacist. This review will address the physiological changes of pregnancy that may affect glomerular disease presentation, activity, and diagnosis; specific glomerular diseases primary and secondary to systemic diseases in the context of pregnancy; fetal and maternal complications and long-term effects; diagnosis and differential diagnosis; and treatment strategies that are considered relatively safe with respect to fetal intrauterine exposure.

Original languageEnglish (US)
Pages (from-to)402-410
Number of pages9
JournalAdvances in Chronic Kidney Disease
Volume20
Issue number5
DOIs
StatePublished - Sep 1 2013

Keywords

  • Glomerular disease
  • Kidney disease
  • Preeclampsia
  • Pregnancy
  • Proteinuria

ASJC Scopus subject areas

  • Nephrology

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