TY - JOUR
T1 - Why smaller animals have higher heart rates
AU - Westerhof, N.
AU - Elzinga, G.
AU - Chadwick, R.
AU - Allen, D.
AU - Li, J. K.
AU - Ford, L. E.
AU - Arts, T.
AU - Ritman, E.
PY - 1993
Y1 - 1993
N2 - Diastolic blood pressure is the main driving pressure for coronary perfusion. Diastolic pressure depends on mean pressure and the ratio of the decay time of aortic pressure in diastole (τ) and the duration of diastole (T(d)). The ratio of τ, a morphological, arterial parameter, and T(d), a functional, cardiac parameter, is the same in all mammals. This could mean that smaller animals have higher heart rates i.e. shorter duration of diastole to match the shorter time constant of the diastolic pressure decay and to guarantee adequate coronary perfusion.
AB - Diastolic blood pressure is the main driving pressure for coronary perfusion. Diastolic pressure depends on mean pressure and the ratio of the decay time of aortic pressure in diastole (τ) and the duration of diastole (T(d)). The ratio of τ, a morphological, arterial parameter, and T(d), a functional, cardiac parameter, is the same in all mammals. This could mean that smaller animals have higher heart rates i.e. shorter duration of diastole to match the shorter time constant of the diastolic pressure decay and to guarantee adequate coronary perfusion.
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U2 - 10.1007/978-1-4615-2946-0_31
DO - 10.1007/978-1-4615-2946-0_31
M3 - Article
C2 - 8184772
AN - SCOPUS:0027754795
SN - 0065-2598
VL - 346
SP - 319
EP - 323
JO - Advances in experimental medicine and biology
JF - Advances in experimental medicine and biology
ER -