Why should dialysis benefit schizophrenia?

I. M. Cohen, S. C. Scheiber, H. Yamamura

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

If dialysis is successful for the treatment of schzophrenia, the artificial kidney must be removing something which the human kidney cannot, unless other nonspecific factors are involved. Either there is an abnormal compound present which is retained by normal renal tubular transport processes, or the kidney of a schizophrenic must be abnormal in that it fails to excrete a normally present compound. Since the latter explanation is less probable, biochemical research should focus on classes of compounds which are known to be handled differently by the artificial kidney than by the human kidney. A dialyzable 'schizophrenic toxin' might be a nonprotein, nonprotein-bound compound of molecular weight below 500 daltons such as an organic acid or base. Proteins, peptides, amino acids, and trace elements are less likely possibilities.

Original languageEnglish (US)
Pages (from-to)475-477
Number of pages3
JournalJournal of Nervous and Mental Disease
Volume167
Issue number8
StatePublished - 1979
Externally publishedYes

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Dialysis
Schizophrenia
Artificial Kidneys
Kidney
Amino Acids, Peptides, and Proteins
Trace Elements
Molecular Weight
Acids
Research

ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

Cohen, I. M., Scheiber, S. C., & Yamamura, H. (1979). Why should dialysis benefit schizophrenia? Journal of Nervous and Mental Disease, 167(8), 475-477.

Why should dialysis benefit schizophrenia? / Cohen, I. M.; Scheiber, S. C.; Yamamura, H.

In: Journal of Nervous and Mental Disease, Vol. 167, No. 8, 1979, p. 475-477.

Research output: Contribution to journalArticle

Cohen, IM, Scheiber, SC & Yamamura, H 1979, 'Why should dialysis benefit schizophrenia?', Journal of Nervous and Mental Disease, vol. 167, no. 8, pp. 475-477.
Cohen IM, Scheiber SC, Yamamura H. Why should dialysis benefit schizophrenia? Journal of Nervous and Mental Disease. 1979;167(8):475-477.
Cohen, I. M. ; Scheiber, S. C. ; Yamamura, H. / Why should dialysis benefit schizophrenia?. In: Journal of Nervous and Mental Disease. 1979 ; Vol. 167, No. 8. pp. 475-477.
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