Why is evidence-based medicine so harsh on vaccines? An exploration of the method and its natural biases

Robert M. Jacobson, Paul V. Targonski, Gregory A. Poland

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Vaccines have been hailed as one of the greatest success stories of public health in the 20th century. The 20th century also produced a call for evidence-based medicine (EBM) with applications inclusive of preventive health. Since then, several major EBM analyses have called into question vaccine practices well-accepted by physicians, public health officials, and even the lay public. For example, while counter to existing studies and policies, EBM analyses have concluded that data are lacking to support influenza vaccination of healthcare workers to prevent flu complications among the elderly. In this review, we examine the criticisms and consider the shortcomings in the field of vaccinology as well as in the methodology of evidence-based medicine.

Original languageEnglish (US)
Pages (from-to)3165-3169
Number of pages5
JournalVaccine
Volume25
Issue number16 SPEC. ISS.
DOIs
StatePublished - Apr 20 2007

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Evidence-Based Medicine
medicine
Vaccines
vaccines
public health
Public Health
human influenza
vaccine development
health care workers
methodology
physicians
influenza
Human Influenza
Vaccination
vaccination
Delivery of Health Care
Physicians
Health

Keywords

  • Evidence-based medicine
  • Vaccination
  • Vaccines

ASJC Scopus subject areas

  • Immunology
  • Microbiology
  • Virology
  • Infectious Diseases
  • Public Health, Environmental and Occupational Health
  • veterinary(all)

Cite this

Why is evidence-based medicine so harsh on vaccines? An exploration of the method and its natural biases. / Jacobson, Robert M.; Targonski, Paul V.; Poland, Gregory A.

In: Vaccine, Vol. 25, No. 16 SPEC. ISS., 20.04.2007, p. 3165-3169.

Research output: Contribution to journalArticle

Jacobson, Robert M. ; Targonski, Paul V. ; Poland, Gregory A. / Why is evidence-based medicine so harsh on vaccines? An exploration of the method and its natural biases. In: Vaccine. 2007 ; Vol. 25, No. 16 SPEC. ISS. pp. 3165-3169.
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