What factors predispose patients to acute respiratory distress syndrome?

Yewande Odeyemi, Alice Gallo De Moraes, Ognjen Gajic

Research output: Chapter in Book/Report/Conference proceedingChapter


Sepsis, pneumonia, and shock are the most common conditions predisposing to acute respiratory distress syndrome (ARDS) and certain host genetic variants have been associated with the development of ARDS. Risk modifiers include abuse of alcohol and tobacco, malnutrition, and obesity. The Lung Injury Prediction Score (LIPS) and the simplified Early Acute Lung Injury Score predict ARDS based on clinical and investigational criteria. Hospital-acquired ARDS may result from a medley factors of which high tidal volume ventilation, high oxygen concentration, and plasma transfusion are most commonly implicated. The Checklist for Lung Injury Prevention (CLIP) has been developed to ensure compliance with evidence-based practice that may affect ARDS occurrence. To date, no pharmacologic intervention has been shown to prevent ARDS.

Original languageEnglish (US)
Title of host publicationEvidence-Based Practice of Critical Care
ISBN (Electronic)9780323640688
StatePublished - Jan 1 2019


  • ARDS
  • CLIP
  • Genetics
  • LIPS
  • Prevention
  • Risk factors

ASJC Scopus subject areas

  • Medicine(all)


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