Vulnerable Plaque

Detection and Management

Mario Gössl, Daniele Versari, Heike Hildebrandt, Dallit Mannheim, Monica L. Olson, Lilach O Lerman, Amir Lerman

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Because most myocardial infarctions result from the rupture of a plaque that did not significantly compromise the coronary lumen before the event, experts widely accept that the morphology, composition, and degree of inflammation of a coronary atherosclerotic plaque is more important than the degree of luminal stenosis. Two depicting examples are the concentric, calcified lesion that shows significant luminal stenosis but is stable because of the stabilizing clasp of calcification. In contrast, a smaller but inflamed thin fibrous cap atheroma with a big lipid/necrotic core may rupture and cause an immediate fatal coronary occlusion.

Original languageEnglish (US)
Pages (from-to)573-601
Number of pages29
JournalMedical Clinics of North America
Volume91
Issue number4
DOIs
StatePublished - Jul 2007

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Atherosclerotic Plaques
Rupture
Pathologic Constriction
Coronary Occlusion
Myocardial Infarction
Inflammation
Lipids

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Vulnerable Plaque : Detection and Management. / Gössl, Mario; Versari, Daniele; Hildebrandt, Heike; Mannheim, Dallit; Olson, Monica L.; Lerman, Lilach O; Lerman, Amir.

In: Medical Clinics of North America, Vol. 91, No. 4, 07.2007, p. 573-601.

Research output: Contribution to journalArticle

Gössl, M, Versari, D, Hildebrandt, H, Mannheim, D, Olson, ML, Lerman, LO & Lerman, A 2007, 'Vulnerable Plaque: Detection and Management', Medical Clinics of North America, vol. 91, no. 4, pp. 573-601. https://doi.org/10.1016/j.mcna.2007.03.004
Gössl M, Versari D, Hildebrandt H, Mannheim D, Olson ML, Lerman LO et al. Vulnerable Plaque: Detection and Management. Medical Clinics of North America. 2007 Jul;91(4):573-601. https://doi.org/10.1016/j.mcna.2007.03.004
Gössl, Mario ; Versari, Daniele ; Hildebrandt, Heike ; Mannheim, Dallit ; Olson, Monica L. ; Lerman, Lilach O ; Lerman, Amir. / Vulnerable Plaque : Detection and Management. In: Medical Clinics of North America. 2007 ; Vol. 91, No. 4. pp. 573-601.
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