Voxel-based morphometry and its application to movement disorders

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27 Scopus citations

Abstract

Voxel-based morphometry (VBM) is an automated technique that assesses patterns of regional grey and white matter atrophy on MRI between two groups of subjects. VBM has been used to assess patterns of regional atrophy in subjects with movement disorders. These studies have demonstrated specific patterns of regional loss in each disorder, compared different movement disorders to look for differences that could be diagnostically useful, and have correlated regions of loss to cognitive and motor deficits in these subjects. This article will review the findings of these studies and discuss the role of VBM in movement disorders.

Original languageEnglish (US)
Pages (from-to)S406-S416
JournalParkinsonism and Related Disorders
Volume13
Issue numberSUPPL. 3
DOIs
StatePublished - Dec 1 2007

Keywords

  • Corticobasal degeneration
  • Huntington's disease
  • Magnetic resonance imaging
  • Multiple system atrophy
  • Parkinson's disease
  • Progressive supranuclear palsy
  • Spinocerebellar ataxia
  • Voxel-based morphometry

ASJC Scopus subject areas

  • Neurology
  • Geriatrics and Gerontology
  • Clinical Neurology

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