Vitamin D and calcium hormones in pregnancy

Rajiv Kumar, W. R. Cohen, F. H. Epstein

Research output: Contribution to journalArticle

35 Scopus citations


There is no time of life, and there are few diseases, in which such massive shifts in calcium occur so regularly as during pregnancy. Fetal bone formation demands that 25 to 30 g of calcium be deposited in the fetal skeleton, almost all of it during the second half of gestation. To prepare for this process and for the losses of calcium occur with lactation, maternal calcium accretion begins early in pregnancy. Well before the major fetal ossification of late pregnancy, intestinal absorption of calcium is enhanced in the mother and her bone mass increases, a unique event in the normal adult. New information has thrown light on the hormonal control of these changes in calcium metabolism and their close relation to vitamin D.

Original languageEnglish (US)
Pages (from-to)1143-1144
Number of pages2
JournalNew England Journal of Medicine
Issue number20
StatePublished - 1980


ASJC Scopus subject areas

  • Medicine(all)

Cite this

Kumar, R., Cohen, W. R., & Epstein, F. H. (1980). Vitamin D and calcium hormones in pregnancy. New England Journal of Medicine, 302(20), 1143-1144.