Viscoelastic tissue mimicking phantom validation study with shear wave elasticity imaging and viscoelastic spectroscopy

Carolina Amador, Randall R. Kinnick, Matthew W Urban, Mostafa Fatemi, James F Greenleaf

Research output: Chapter in Book/Report/Conference proceedingConference contribution

5 Scopus citations

Abstract

Acoustic radiation force-based shear wave elasticity (SWE) methods are used to characterize soft tissue pathologies by quantifying tissue viscoelastic (VE) properties. To adequately evaluate SWE methods measurements of VE properties, it is important to characterize VE properties of tissue mimicking phantoms with an independent method. In this study a VE tissue mimicking phantom was developed and its concentration was modified to vary the shear viscosity. Three VE phantoms were studied with SWE and hyper frequency viscoelastic spectroscopy (HFVS). The VE properties were quantified by fitting a Kelvin-Voigt fractional derivative model to the measured shear wave speed. The mean shear elasticity of the three phantoms was from 3.4 to 3.7 kPa, the mean shear viscosity was from 1.7 to 17.4 Pa•s and the power of the fractional derivative model varied from 0.6 to 0.9.

Original languageEnglish (US)
Title of host publication2015 IEEE International Ultrasonics Symposium, IUS 2015
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Print)9781479981823
DOIs
StatePublished - Nov 13 2015
EventIEEE International Ultrasonics Symposium, IUS 2015 - Taipei, Taiwan, Province of China
Duration: Oct 21 2015Oct 24 2015

Other

OtherIEEE International Ultrasonics Symposium, IUS 2015
CountryTaiwan, Province of China
CityTaipei
Period10/21/1510/24/15

Keywords

  • phantoms
  • spectroscopy
  • SWEI
  • viscoelasticity

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

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