Viscoelastic measurements on perfused and non-perfused swine renal cortex in vivo

Carolina Amador, Matthew W. Urban, Randall Kinnick, Shigao Chen, James F. Greenleaf

Research output: Chapter in Book/Report/Conference proceedingConference contribution

6 Scopus citations

Abstract

Renal fibrosis threatens kidney viability and fibrosis has been associated with altered tissue structure affecting the biomechanical properties of the kidney, such as elasticity and viscosity. Although there are limited studies regarding viscoelastic properties of renal tissue, an in vivo renal MRE study suggests that shear elasticity changes as a result of hemodynamic variables. A newly emerging method called Shearwave Dispersion Ultrasound Vibrometry (SDUV) offers a tool to determine renal elasticity and viscosity in vivo. SDUV quantifies both elasticity and viscosity by evaluating dispersion of shear wave propagation speed versus its frequency. The purpose of this study is to evaluate the feasibility of SDUV for in vivo measurements of elasticity and viscosity on normal swine kidney consequent to acute changes in renal hemodynamics.

Original languageEnglish (US)
Title of host publication2010 IEEE International Ultrasonics Symposium, IUS 2010
Pages1530-1533
Number of pages4
DOIs
StatePublished - 2010
Event2010 IEEE International Ultrasonics Symposium, IUS 2010 - San Diego, CA, United States
Duration: Oct 11 2010Oct 14 2010

Publication series

NameProceedings - IEEE Ultrasonics Symposium
ISSN (Print)1051-0117

Other

Other2010 IEEE International Ultrasonics Symposium, IUS 2010
Country/TerritoryUnited States
CitySan Diego, CA
Period10/11/1010/14/10

Keywords

  • Renal cortex
  • elasticity
  • viscosity

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

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