Virtual resection of gliomas: Effect of extent of resection on recurrence

K. R. Swanson; E. C. Alvord; J. D. Murray

doi:10.1016/S0895-7177(03)00129-8

Virtual resection of gliomas: Effect of extent of resection on recurrence

K. R. Swanson, E. C. Alvord, J. D. Murray

Neurologic Surgery

Research output: Contribution to journal › Article › peer-review

51 Scopus citations

Abstract

Gliomas are diffuse and invasive neoplasms of the brain with the ability to recur despite extensive treatment. We have developed a mathematical model to describe the growth and invasion of glioma cells throughout an anatomically accurate virtual human brain as well as the effects of operation on these lesions. The model predicts behavior similar to that observed clinically and presents itself as a possible tool for future clinical application.

Original language	English (US)
Pages (from-to)	1177-1190
Number of pages	14
Journal	Mathematical and Computer Modelling
Volume	37
Issue number	11
DOIs	https://doi.org/10.1016/S0895-7177(03)00129-8
State	Published - Jun 1 2003

Keywords

Brain tumor
Glioma
Invasion
Mathematical model
Resection

ASJC Scopus subject areas

Modeling and Simulation
Computer Science Applications

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10.1016/S0895-7177(03)00129-8

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abstract = "Gliomas are diffuse and invasive neoplasms of the brain with the ability to recur despite extensive treatment. We have developed a mathematical model to describe the growth and invasion of glioma cells throughout an anatomically accurate virtual human brain as well as the effects of operation on these lesions. The model predicts behavior similar to that observed clinically and presents itself as a possible tool for future clinical application.",

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T2 - Effect of extent of resection on recurrence

AU - Swanson, K. R.

AU - Alvord, E. C.

AU - Murray, J. D.

PY - 2003/6/1

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N2 - Gliomas are diffuse and invasive neoplasms of the brain with the ability to recur despite extensive treatment. We have developed a mathematical model to describe the growth and invasion of glioma cells throughout an anatomically accurate virtual human brain as well as the effects of operation on these lesions. The model predicts behavior similar to that observed clinically and presents itself as a possible tool for future clinical application.

AB - Gliomas are diffuse and invasive neoplasms of the brain with the ability to recur despite extensive treatment. We have developed a mathematical model to describe the growth and invasion of glioma cells throughout an anatomically accurate virtual human brain as well as the effects of operation on these lesions. The model predicts behavior similar to that observed clinically and presents itself as a possible tool for future clinical application.

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KW - Glioma

KW - Invasion

KW - Mathematical model

KW - Resection

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ER -

Virtual resection of gliomas: Effect of extent of resection on recurrence

Abstract

Keywords

ASJC Scopus subject areas

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