Virtual resection of gliomas: Effect of extent of resection on recurrence

K. R. Swanson, E. C. Alvord, J. D. Murray

Research output: Contribution to journalArticlepeer-review

51 Scopus citations

Abstract

Gliomas are diffuse and invasive neoplasms of the brain with the ability to recur despite extensive treatment. We have developed a mathematical model to describe the growth and invasion of glioma cells throughout an anatomically accurate virtual human brain as well as the effects of operation on these lesions. The model predicts behavior similar to that observed clinically and presents itself as a possible tool for future clinical application.

Original languageEnglish (US)
Pages (from-to)1177-1190
Number of pages14
JournalMathematical and Computer Modelling
Volume37
Issue number11
DOIs
StatePublished - Jun 1 2003

Keywords

  • Brain tumor
  • Glioma
  • Invasion
  • Mathematical model
  • Resection

ASJC Scopus subject areas

  • Modeling and Simulation
  • Computer Science Applications

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